In vitro organ culture models of asthma

Drug Discovery Today: Disease Models

Volumn 6, Issue 4, 2009, Pages 137-144

  Huang, Song ^a   Wiszniewski, Ludovic ^a   Derouette, Jean Paul ^a   Constant, Samuel ^a  

^a Epithelix   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E; INTERLEUKIN 17F; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8;

ANTIGEN PRESENTING CELL; ASTHMA; BACTERIAL INFECTION; BASOPHIL; CELL DIFFERENTIATION; CIGARETTE SMOKING; CROSS LINKING; DENDRITIC CELL; EOSINOPHIL; HELPER CELL; HUMAN; IMMUNE RESPONSE; IMMUNOMODULATION; IMMUNOSTIMULATION; IN VITRO STUDY; MAST CELL; NONHUMAN; PATHOGENESIS; RESPIRATORY EPITHELIUM; REVIEW; VIRUS INFECTION;

EID: 77956342684     PISSN: 17406757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddmod.2009.08.002     Document Type: Review

References (61)

1. K.C. Barnes, and D.G. Marsh The genetics and complexity of allergy and asthma Immunol. Today 19 1998 325 332
2. W.O. Cookson Asthma genetics Chest 121 Suppl 2002 7S 13S
3. The Collaborative Study on the Genetics of Asthma (CSGA) A genome-wide search for asthma susceptibility loci in ethnically diverse populations Nat. Genet. 15 1997 389 392
4. C. Ober, and S. Hoffjan Asthma genetics 2006: the long and winding road to gene discovery Genes Immun. 7 2006 95 100
5. Y. Yokouchi Significant evidence for linkage of mite-sensitive childhood asthma to chromosome 5q31-q33 near the interleukin 12 B locus by a genome-wide search in Japanese families Genomics 66 2000 152 160
6. M.M. Epstein Modeling allergic asthma: from in vitro assays to virtual patients Drug Discov. Today: Dis. Models 1 2004 387 394
7. S. Verstraelen Cell types involved in allergic asthma and their use in in vitro models to assess respiratory sensitization Toxicol. In Vitro 22 2008 1419 1431
8. Y. Rochman, and W.J. Leonard Thymic stromal lymphopoietin: a new cytokine in asthma Curr. Opin. Pharmacol. 8 2008 249 254
9. S.F. Ziegler, and Y.J. Liu Thymic stromal lymphopoietin in normal and pathogenic T cell development and function Nat. Immunol. 7 2006 709 714
10. S. Esnault Thymic stromal lymphopoietin (TSLP) as a bridge between infection and atopy Int. J. Clin. Exp. Pathol. 1 2008 325 330
11. L. Shi Local blockade of TSLP receptor alleviated allergic disease by regulating airway dendritic cells Clin. Immunol. 129 2008 202 210
12. S.L. Friend A thymic stromal cell line supports in vitro development of surface IgM+ B cells and produces a novel growth factor affecting B and T lineage cells Exp. Hematol. 22 1994 321 328
13. D.E. Isaksen Requirement for stat5 in thymic stromal lymphopoietin- mediated signal transduction J. Immunol. 163 1999 5971 5977
14. S. Ying Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity J. Immunol. 174 2005 8183 8190
15. A. Al-Shami A role for TSLP in the development of inflammation in an asthma model J. Exp. Med. 202 2005 829 839
16. B. Zhou Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice Nat. Immunol. 6 2005 1047 1053
17. J. Yoo Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin J. Exp. Med. 202 2005 541 549
18. C. Zaph Epithelial-cell-intrinsic IKK-beta expression regulates intestinal immune homeostasis Nature 446 2007 552 556
19. V. Soumelis Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP Nat. Immunol. 3 2002 673 680
20. S.T. Holgate The airway epithelium is central to the pathogenesis of asthma Allergol. Int. 57 2008 1 10
21. M.J. Holtzman Immunity, inflammation, and remodeling in the airway epithelial barrier: epithelial-viral-allergic paradigm Physiol. Rev. 82 2002 19 46
22. G. Folkerts, and F.P. Nijkamp Airway epithelium: more than just a barrier! Trends Pharmacol. Sci. 19 1998 334 341
23. S. Laberge, and S. El Bassam Cytokines, structural cells of the lungs and airway inflammation Paediatr. Respir. Rev. 5 Suppl. A 2004 S41 45
24. S. Suzuki Expression of interleukin-17F in a mouse model of allergic asthma Int. Arch. Allergy Immunol. 143 Suppl 1 2007 89 94
25. Y. Nakamura Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to T(H)2-type immune responses and airway inflammation J. Allergy Clin. Immunol. 122 2008 1208 1214
26. K. Ito Steroid-resistant neutrophilic inflammation in a mouse model of an acute exacerbation of asthma Am. J. Respir. Cell Mol. Biol. 39 2008 543 550
27. B. Raju In situ activation of helper T cells in the lung Infect. Immun. 69 2001 4790 4798
28. T.A. Out Local T-cell activation after segmental allergen challenge in the lungs of allergic dogs Immunology 105 2002 499 508
29. S.L. Constant Resident lung antigen-presenting cells have the capacity to promote Th2 T cell differentiation in situ J. Clin. Invest. 110 2002 1441 1448
30. S.T. Holgate Local genetic and environmental factors in asthma disease pathogenesis: chronicity and persistence mechanisms Eur. Respir. J. 29 2007 793 803
31. L. Zhang Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathology J. Virol. 76 2002 5654 5666
32. M. Kesimer Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways? Am. J. Physiol. Lung Cell Mol. Physiol. 296 2009 L92 L100
33. See MucilAir™ products on http://www.epithelix.com
34. See EpiAirway™ products on http://www.mattek.com
35. M. Harada Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells Am. J. Respir. Cell Mol. Biol. 40 2009 368 374
36. S.J. Santegoets Human dendritic cell line models for DC differentiation and clinical DC vaccination studies J. Leukoc. Biol. 84 2008 1364 1373
37. T.B. Casale, and J.R. Stokes Immunomodulators for allergic respiratory disorders J. Allergy Clin. Immunol. 121 2008 288 296 297-288 quiz
38. M. Frieri Montelukast inhibits interleukin-5 mRNA expression and cysteinyl leukotriene production in ragweed and mite-stimulated peripheral blood mononuclear cells from patients with asthma Allergy Asthma Proc. 24 2003 359 366
39. L. Tang Expression and characterization of recombinant canine IL-13 receptor alpha2 protein and its biological activity in vitro Mol. Immunol. 39 2003 719 727
40. C. Nilsson Low numbers of interleukin-12-producing cord blood mononuclear cells and immunoglobulin E sensitization in early childhood Clin. Exp. Allergy 34 2004 373 380
41. D.S. Lang Interactions between human bronchoepithelial cells and lung fibroblasts after ozone exposure in vitro Toxicol. Lett. 96-97 1998 13 24
42. M. Mogel A new coculture-system of bronchial epithelial and endothelial cells as a model for studying ozone effects on airway tissue Toxicol. Lett. 96-97 1998 25 32
43. C.K. Wong Role of p38 MAPK and NF-kB for chemokine release in coculture of human eosinophils and bronchial epithelial cells Clin. Exp. Immunol. 139 2005 90 100
44. H. Ishii Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment Respir. Res. 6 2005 87
45. S. Zhang Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: an in vitro co-culture model of airway remodeling in asthma Lab. Invest. 79 1999 395 405
46. A. Wohlsen The early allergic response in small airways of human precision-cut lung slices Eur. Respir. J. 21 2003 1024 1032
47. L. Tan Immunomodulatory effect of cytosine-phosphate-guanosine (CpG)-oligonucleotides in nonasthmatic chronic rhinosinusitis: an explant model Am. J. Rhinol. Allergy 23 2009 123 129
48. C. Morin Organ-cultured airway explants: a new model of airway hyperresponsiveness Exp. Lung Res. 31 2005 719 744
49. M. Henjakovic Ex vivo lung function measurements in precision-cut lung slices (PCLS) from chemical allergen-sensitized mice represent a suitable alternative to in vivo studies Toxicol. Sci. 106 2008 444 453
50. M.M. Epstein Do mouse models of allergic asthma mimic clinical disease? Int. Arch. Allergy Immunol. 133 2004 84 100
51. M.B. Headley TSLP conditions the lung immune environment for the generation of pathogenic innate and antigen-specific adaptive immune responses J. Immunol. 182 2009 1641 1647
52. C. Duez An in vivo model of allergic inflammation: pulmonary human cell infiltrate in allergen-challenged allergic Hu-SCID mice Eur. J. Immunol. 26 1996 1088 1093
53. C. Duez House dust mite-induced airway changes in hu-SCID mice Am. J. Respir. Crit. Care Med. 161 2000 200 206
54. U. Herz Increased airway responsiveness, allergy-type-I skin responses and systemic anaphylaxis in a humanized-severe combined immuno-deficiency mouse model Clin. Exp. Allergy 34 2004 478 487
55. D.A. Deshpande, and R.B. Penn Targeting G protein-coupled receptor signaling in asthma Cell Signal. 18 2006 2105 2120
56. L. Jacob Virtual screening of GPCRs: an in silico chemogenomics approach BMC Bioinformatics 9 2008 363
57. B. Fabry, and J.J. Fredberg Mechanotransduction, asthma, and airway smooth muscle Drug Discov. Today: Dis. Models 4 2007 131 137
58. J. Latourelle Dynamic equilibration of airway smooth muscle contraction during physiological loading J. Appl. Physiol. 92 2002 771 779
59. M.N. Oliver Airway hyperresponsiveness, remodeling, and smooth muscle mass: right answer, wrong reason? Am. J. Respir. Cell Mol. Biol. 37 2007 264 272
60. T. Martonen In silico modeling of asthma Adv. Drug Deliv. Rev. 55 2003 829 849
61. A. Llop-Guevara In vivo to in silico iterations to investigate aeroallergen-host interactions PLoS One 3 2008 e2426