Organ-cultured airway explants: A new model of airway hyperresponsiveness

Experimental Lung Research

Volumn 31, Issue 7, 2005, Pages 719-744

  Morin, Caroline ^a   Proteau, Sonia ^a   Rousseau, Eric ^a   Brayden, Joseph ^b  

^a UNIVERSITY OF SHERBROOKE   (Canada)

^b UNIVERSITY OF VERMONT   (United States)

Author keywords

Airway smooth muscle; Hyperresponsiveness; Isometric tension; Membrane potential; Organ culture

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; CALCIUM ION; CARBACHOL; HISTAMINE; HISTAMINE AGONIST; INDOMETACIN; ISOPRENALINE; MUSCARINIC AGENT; NORADRENALIN; POTASSIUM CHLORIDE; PROSTANOID; SEROTONIN AGONIST; SPASMOGEN; THAPSIGARGIN; THROMBOXANE RECEPTOR STIMULATING AGENT;

AIRWAY HYPERRESPONSIVENESS; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTHMA; BRONCHUS; CONTROLLED STUDY; CULTURE MEDIUM; ELECTROPHYSIOLOGY; EXPLANT; FEMALE; FLUORESCENCE MICROSCOPY; GUINEA PIG; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE DEPOLARIZATION; MEMBRANE STEADY POTENTIAL; MUSCLE ISOMETRIC CONTRACTION; NICK END LABELING; NONHUMAN; ORGAN CULTURE; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT DISEASE; SMOOTH MUSCLE; SUBMUCOSA; TIME; TRACHEA;

EID: 25444456605     PISSN: 01902148     EISSN: 15210499     Source Type: Journal    
DOI: 10.1080/01902140500248613     Document Type: Article

References (33)

1. Bergner A, Sanderson MJ: Acetylcholine-induced calcium signaling and contraction of airway smooth muscle cells in lung slices. J Gen Physiol. 2002;119:187-198.
2. Chakir J, Page N, Hamid Q, Laviolette M, Boulet LP, Rouabhia M: Bronchial mucosa produced by tissue engineering: a new tool to study cellular interactions in asthma. J Allergy Clin Immunol. 2001;107:36-40.
3. Halayko AJ, Camoretti-Mercado B, Forsythe SM, Vieira JE, Mitchell RW, Wylam ME, Hershenson MB, Solway J: Divergent differentiation paths in airway smooth muscle culture: induction of functionally contractile myocytes. Am J Physiol (Lung Cell Mol Physiol). 1999;27:L197-L206.
4. Goulet F, Boulet LP, Chakir J, Tremblay N, Dube J, Laviolette M, Boutet M, Xu W, Germain L, Auger FA: Morphologic and functional properties of bronchial cells isolated from normal and asthmatic subjects. Am J Respir Cell Mol Biol. 1996;15:312-318.
5. Joos GF: Bronchial hyperresponsiveness: too complex to be useful? Curr Opin Pharmacol. 2003; 3:233-238.
6. Naghshin J, Wang L, Pare PD, Seow CY: Adaptation to chronic length change in explanted airway smooth muscle. J Appl Physiol. 2003;95:448-453.
7. Moir LM, Ward JP, Hirst SJ: Contractility and phenotype of human bronchiole smooth muscle after prolonged fetal bovine serum exposure. Exp Lung Res. 2003;6:339-359.
8. Stoker AW, Streuli CH, Martins-Green M, Bissell MJ: Designer microenvironments for the analysis of cell and tissue function. Curr Opin Cell Biol. 1990;5:864-874.
9. Kelsen SG, Johnson RA, Mest S, Stauber Z, Zhou S, Aksoy M, Hilfer SR: Explant culture of rabbit tracheobronchial epithelium: structure and prostaglandin metabolism. Am J Respir Cell Mol Biol. 1993;8:472-479.
10. Bakker EN, Sorop O, Spaan JA, VanBavel E: Remodeling of resistance arteries in organ culture is modulated by pressure and pressure pulsation and depends on vasomotion. Am J Physiol Heart Circ Physiol. 2004;286:H2052-H2056.
11. Bakker EN, van Der Meulen ET, Spaan JA, VanBavel E: Organoid culture of cannulated rat resistance arteries: effect of serum factors on vasoactivity and remodeling. Am J Physiol Heart Circ Physiol. 2000;278:H1233-H1240.
12. Gross I, Freedman RM, Wilson CM, Lindsey S: Organotypic culture of fetal rat lung: evaluation and comparison with organ culture. Am Rev Respir Dis. 1981;123:313-319.
13. Morais R, Watters C, Binda A, Vauclair R, Band P: Epithelial lesions induced by alpha particles and cigarette smoke condensate in organotypic culture of human bronchus. Cancer Res. 1982;82: 21-31.
14. Adner M, Rose AC, Zhang Y, Sward K, Benson M, Uddman R, Shankley NP, Cardell LO: An assay to evaluate the long-term effects of inflammatory mediators on murine airway smooth muscle: evidence that TNFα up-regulates 5-HT (2A)-mediated contraction. Br J Pharmacol. 2002;137: 971-982.
15. Cloutier M, Campbell S, Basora N, Proteau S, Payet MD, Rousseau E: 20-HETE inotropic effects involve the activation of non-selective cationic current in airway mooth muscle. Am J Physiol (Lung Cell Mol Physiol). 2003;285:L560-L568.
16. 2+ pools and Rho kinase pathway. Am J Physiol Lung Cell Mol Physiol. 2004;287:L631-L640.
17. Hanna CJ, Roth SH: The guinea pig tracheobronchial spiral strip: responses to selected agonists. Can J Physiol Pharmacol. 1978;56:823-827.
18. Ca channel activation and hyperpolarization. Am J Physiol Lung Cell Mol Physiol. 2001;280:L965-L973.
19. Michalopoulos GK, Bowen WC, Mule K, Stolz DB: Histological organization in hepatocyte organoid cultures. Am J Pathol. 2001;159:1877-1887.
20. Lesur O, Brisebois M, Thibodeau A, Chagnon F, Lane D, Füllöp T: Role of IFN-γ and IL-2 in rat lung epithelial cell migration and apoptosis after oxidant injury. Am J Physiol. 2002;286: L4-L14.
21. Canning BJ, Undem BJ, Karakousis PC, Dey RD: Effects of organotypic culture on parasympathetic innervation of guinea pig trachealis. Am J Physiol. 1996;271:L698-L706.
22. Gosens R, Meurs H, Bromhaar MM, McKay S, Nelemans SA, Zaagsma J: Functional characterization of serum- and growth factor-induced phenotypic changes in intact bovine tracheal smooth muscle. Br J Pharmacol. 2002;137:459-466.
23. Somlyo AP, Somlyo AV: Signal transduction by G-protein, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. J Physiol. 2000;522:177-185.
24. Fedan JS, Frazer DG: Influence of epithelium on the reactivity of guinea pig isolated, perfused trachea to bronchoactive drugs. J Pharmacol Exp Then 1992;262:741-750.
25. Folkerts G, Nijkamp FP: Airway epithelium: more than just a barrier! Trends Pharmacol Sci. 1998;19:334-341.
26. Rogers MJ, Ward SM, Horner MA, Sanders KM, Horowitz B: Characterization of the properties of canine colonic smooth muscle in culture. Am J Physiol. 1993;265:C1433-C1442.
27. 2+. Can J Physiol pharmacol. 1996;74:1236-1248.
28. 2+ in bovine airway smooth muscle. Br J Pharmacol. 2003;139:1203-1211.
29. Takemoto M, Takagi K, Ogino K, Tomita T: Comparison of contractions produced by carbachol, thapsigargin and cyclopiazonic acid in the guinea-pig tracheal muscle. Br J Pharmacol. 1998;124:1449-1454.
30. Sims SM, Jiao Y, Zheng ZG: Intracellular calcium stores in isolated tracheal smooth muscle cells. Am J Physiol (Lung Cell Mol Physiol). 1996;271:L300-L309.
31. Featherstone RL, Robinson C, Holgate ST, Church MK: Evidence for thromboxane receptor mediated contraction of guinea-pig and human airways in vitro by prostaglandin (PG) D2, 9 alpha11 beta-PGF2 and PGF2 alpha. Naunyn Schmiedebergs Arch Pharmacol. 1990;341:439-443.
32. Funk CD: Prostaglandins and leukotrienes: advances in eicosanoid biology. Science. 2001;294:1871-1875.
33. Mitzner W, Brown RH: Potential mechanism of hyper-responsive airways. Am J Respir Crit Care Med. 2000;161:1619-1623.