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Volumn 23, Issue 2, 2009, Pages 123-129

Immunomodulatory effect of cytosine-phosphate-guanosine (CpG)-oligonucleotides in nonasthmatic chronic rhinosinusitis: An explant model

Author keywords

Asthma; CpG ODN; Eosinophilic mucus chronic rhinosinusitis; IL 5; Immunostimulatory sequences (ISS); Immunotherapy; Toll like receptor 9

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; CYTOKINE; ENTEROTOXIN; ENTEROTOXIN B; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 5; MESSENGER RNA; PROTEIN P53; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG; CPG ODN 2006; ENTEROTOXIN B, STAPHYLOCOCCAL; IMMUNOLOGIC FACTOR; OLIGODEOXYRIBONUCLEOTIDE; TLR9 PROTEIN, HUMAN;

EID: 67650317890     PISSN: 19458924     EISSN: 19458932     Source Type: Journal    
DOI: 10.2500/ajra.2009.23.3279     Document Type: Article
Times cited : (16)

References (32)
  • 1
    • 9644300929 scopus 로고    scopus 로고
    • Rhinosinusitis: Establishing definitions for clinical research and patient care
    • Meltzer EO, Hamilos DL, Hadley JA, et al. Rhinosinusitis: Establishing definitions for clinical research and patient care. J Allergy Clin Immunol 114:155-212, 2004.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 155-212
    • Meltzer, E.O.1    Hamilos, D.L.2    Hadley, J.A.3
  • 2
    • 33747167956 scopus 로고    scopus 로고
    • Eosinophilic mucus chronic rhinosinusitis: Clinical subgroups or a homogeneous pathogenic entity?
    • Pant H, Kette FE, Smith WB, et al. Eosinophilic mucus chronic rhinosinusitis: Clinical subgroups or a homogeneous pathogenic entity? Laryngoscope 116:1241-1247, 2006.
    • (2006) Laryngoscope , vol.116 , pp. 1241-1247
    • Pant, H.1    Kette, F.E.2    Smith, W.B.3
  • 3
    • 1142273302 scopus 로고    scopus 로고
    • Allergic rhinitis, rhinosinusitis, and asthma: One airway disease
    • Bachert C, Vignola AM, Gevaert P, et al. Allergic rhinitis, rhinosinusitis, and asthma: One airway disease. Immunol Allergy Clin North Am 24:19-43, 2004.
    • (2004) Immunol Allergy Clin North Am , vol.24 , pp. 19-43
    • Bachert, C.1    Vignola, A.M.2    Gevaert, P.3
  • 4
    • 5144227398 scopus 로고    scopus 로고
    • Allergic rhinitis, asthma, and rhinosinusitis: Diseases of the integrated airway
    • Meltzer EO, Szwarcberg J, and Pill MW. Allergic rhinitis, asthma, and rhinosinusitis: Diseases of the integrated airway. J Manag Care Pharm 10:310-317, 2004.
    • (2004) J Manag Care Pharm , vol.10 , pp. 310-317
    • Meltzer, E.O.1    Szwarcberg, J.2    Pill, M.W.3
  • 5
    • 0242719839 scopus 로고    scopus 로고
    • Features of airway remodeling and eosinophilic inflammation in chronic rhinosinusitis: Is the histopathology similar to asthma?
    • Ponikau JU, Sherris DA, Kephart GM, et al. Features of airway remodeling and eosinophilic inflammation in chronic rhinosinusitis: Is the histopathology similar to asthma? J Allergy Clin Immunol 112:877-882, 2003.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 877-882
    • Ponikau, J.U.1    Sherris, D.A.2    Kephart, G.M.3
  • 6
    • 33745946911 scopus 로고    scopus 로고
    • Therapeutic potential of Toll-like receptor 9 activation
    • Krieg AM. Therapeutic potential of Toll-like receptor 9 activation. Nat Rev Drug Discov 5:471-484, 2006.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 471-484
    • Krieg, A.M.1
  • 7
    • 0033980073 scopus 로고    scopus 로고
    • The role of CpG motifs in innate immunity
    • Krieg AM. The role of CpG motifs in innate immunity. Curr Opin Immunol 12:35-43, 2000.
    • (2000) Curr Opin Immunol , vol.12 , pp. 35-43
    • Krieg, A.M.1
  • 8
    • 0347360205 scopus 로고    scopus 로고
    • Toll-like receptors and innate antifungal responses
    • Roeder A, Kirschning CJ, Rupec RA, et al. Toll-like receptors and innate antifungal responses. Trends Microbiol 12:44-49, 2004.
    • (2004) Trends Microbiol , vol.12 , pp. 44-49
    • Roeder, A.1    Kirschning, C.J.2    Rupec, R.A.3
  • 9
    • 0035005506 scopus 로고    scopus 로고
    • CpG oligonucleotide modulation of allergic inflammation
    • Wild JS, and Sur S. CpG oligonucleotide modulation of allergic inflammation. Allergy 56:365-376, 2001.
    • (2001) Allergy , vol.56 , pp. 365-376
    • Wild, J.S.1    Sur, S.2
  • 10
    • 0032534602 scopus 로고    scopus 로고
    • Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice
    • Broide D, Schwarze J, Tighe H, et al. Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice. J Immunol 161:7054-7062, 1998.
    • (1998) J Immunol , vol.161 , pp. 7054-7062
    • Broide, D.1    Schwarze, J.2    Tighe, H.3
  • 11
    • 0034090116 scopus 로고    scopus 로고
    • Regulation of murine airway eosinophilia and Th2 cells by antigen-conjugated CpG oligodeoxynucleotides as a novel antigen-specific immunomodulator
    • Shirota H, Sano K, Kikuchi T, et al. Regulation of murine airway eosinophilia and Th2 cells by antigen-conjugated CpG oligodeoxynucleotides as a novel antigen-specific immunomodulator. J Immunol 164:5575-5582, 2000.
    • (2000) J Immunol , vol.164 , pp. 5575-5582
    • Shirota, H.1    Sano, K.2    Kikuchi, T.3
  • 12
    • 33646251833 scopus 로고    scopus 로고
    • Suppression of allergic response by CpG motif oligodeoxynucleotide-house-dust mite conjugate in animal model of allergic rhinitis
    • Mo JH, Park SW, Rhee CS, et al. Suppression of allergic response by CpG motif oligodeoxynucleotide-house-dust mite conjugate in animal model of allergic rhinitis. Am J Rhinol 20:212-218, 2006.
    • (2006) Am J Rhinol , vol.20 , pp. 212-218
    • Mo, J.H.1    Park, S.W.2    Rhee, C.S.3
  • 13
    • 33749436870 scopus 로고    scopus 로고
    • Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis
    • Creticos PS, Schroeder JT, Hamilton RG, et al. Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis. N Engl J Med 355:1445-1455, 2006.
    • (2006) N Engl J Med , vol.355 , pp. 1445-1455
    • Creticos, P.S.1    Schroeder, J.T.2    Hamilton, R.G.3
  • 14
    • 33646190155 scopus 로고    scopus 로고
    • Toll-like receptor ligands as adjuvants in allergen-specific immunotherapy
    • Johansen P, Senti G, Martinez Gomez JM, et al. Toll-like receptor ligands as adjuvants in allergen-specific immunotherapy. Clin Exp Allergy 35:1591-1598, 2005.
    • (2005) Clin Exp Allergy , vol.35 , pp. 1591-1598
    • Johansen, P.1    Senti, G.2    Martinez Gomez, J.M.3
  • 15
    • 34047108551 scopus 로고    scopus 로고
    • Advances in upper airway diseases and allergen immunotherapy
    • Nelson HS. Advances in upper airway diseases and allergen immunotherapy. J Allergy Clin Immunol 119:872-880, 2007.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 872-880
    • Nelson, H.S.1
  • 16
    • 34047209797 scopus 로고    scopus 로고
    • New allergy intervention strategies: Hitting the mucosal road
    • Wiedermann U, and Mercenier A. New allergy intervention strategies: Hitting the mucosal road. Clin Exp Allergy 37: 473-475, 2007.
    • (2007) Clin Exp Allergy , vol.37 , pp. 473-475
    • Wiedermann, U.1    Mercenier, A.2
  • 17
    • 0037379515 scopus 로고    scopus 로고
    • Intranasal immunotherapy is more effective than intradermal immunotherapy for the induction of airway allergen tolerance in Th2-sensitized mice
    • Takabayashi K, Libet L, Chisholm D, et al. Intranasal immunotherapy is more effective than intradermal immunotherapy for the induction of airway allergen tolerance in Th2-sensitized mice. J Immunol 170:3898-3905, 2003.
    • (2003) J Immunol , vol.170 , pp. 3898-3905
    • Takabayashi, K.1    Libet, L.2    Chisholm, D.3
  • 18
    • 33846914242 scopus 로고    scopus 로고
    • Sinonasal epithelial cell expression of toll-like receptor 9 is decreased in chronic rhinosinusitis with polyps
    • Ramanathan M Jr, Lee WK, Dubin MG, et al. Sinonasal epithelial cell expression of toll-like receptor 9 is decreased in chronic rhinosinusitis with polyps. Am J Rhinol 21:110-116, 2007.
    • (2007) Am J Rhinol , vol.21 , pp. 110-116
    • Ramanathan Jr, M.1    Lee, W.K.2    Dubin, M.G.3
  • 19
    • 38149126990 scopus 로고    scopus 로고
    • Staphylococcus aureus enterotoxin B, protein A, and lipoteichoic acid stimulations in nasal polyps
    • Patou J, Gevaert P, Van Zele T, et al. Staphylococcus aureus enterotoxin B, protein A, and lipoteichoic acid stimulations in nasal polyps. J Allergy Clin Immunol 121:110-115, 2008.
    • (2008) J Allergy Clin Immunol , vol.121 , pp. 110-115
    • Patou, J.1    Gevaert, P.2    Van Zele, T.3
  • 20
    • 39749169685 scopus 로고    scopus 로고
    • The effect of bacterial biofilms on post-sinus surgical outcomes
    • Psaltis A, Weitzel E, Ha KR, et al. The effect of bacterial biofilms on post-sinus surgical outcomes. Am J Rhinol 22: 1-6, 2008.
    • (2008) Am J Rhinol , vol.22 , pp. 1-6
    • Psaltis, A.1    Weitzel, E.2    Ha, K.R.3
  • 21
    • 34548445081 scopus 로고    scopus 로고
    • Human cathelicidin antimicrobial peptide is upregulated in the eosinophilic mucus subgroup of chronic rhinosinusitis patients
    • Ooi E, Wormald PJ, Carney AS, et al. Human cathelicidin antimicrobial peptide is upregulated in the eosinophilic mucus subgroup of chronic rhinosinusitis patients. Am J Rhinol 21:395-401, 2007.
    • (2007) Am J Rhinol , vol.21 , pp. 395-401
    • Ooi, E.1    Wormald, P.J.2    Carney, A.S.3
  • 22
    • 33846067633 scopus 로고    scopus 로고
    • Surfactant protein d expression in chronic rhinosinusitis patients and immune responses in vitro to Aspergillus and Alternaria in a nasal explant model
    • Ooi EH, Wormald PJ, Carney AS, et al. Surfactant protein d expression in chronic rhinosinusitis patients and immune responses in vitro to Aspergillus and Alternaria in a nasal explant model. Laryngoscope 117:51-57, 2007.
    • (2007) Laryngoscope , vol.117 , pp. 51-57
    • Ooi, E.H.1    Wormald, P.J.2    Carney, A.S.3
  • 23
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, and Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25:402-408, 2001.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 25
    • 0034065564 scopus 로고    scopus 로고
    • Eosinophilic mucin rhinosinusitis: A distinct clinicopathological entity
    • Ferguson BJ. Eosinophilic mucin rhinosinusitis: A distinct clinicopathological entity. Laryngoscope 110:799-813, 2000.
    • (2000) Laryngoscope , vol.110 , pp. 799-813
    • Ferguson, B.J.1
  • 26
    • 0037336026 scopus 로고    scopus 로고
    • Inflammation and remodeling of the sinus mucosa in children and adults with chronic sinusitis
    • Sobol SE, Fukakusa M, Christodoulopoulos P, et al. Inflammation and remodeling of the sinus mucosa in children and adults with chronic sinusitis. Laryngoscope 113:410-414, 2003.
    • (2003) Laryngoscope , vol.113 , pp. 410-414
    • Sobol, S.E.1    Fukakusa, M.2    Christodoulopoulos, P.3
  • 27
    • 0141924194 scopus 로고    scopus 로고
    • Eosinophil inflammation of nasal polyp tissue: Relationships with matrix metalloproteinases, tissue inhibitor of metalloproteinase-1, and transforming growth factor-beta1
    • Lee YM, Kim SS, Kim HA, et al. Eosinophil inflammation of nasal polyp tissue: Relationships with matrix metalloproteinases, tissue inhibitor of metalloproteinase-1, and transforming growth factor-beta1. J Kor Med Sci 18:97-102, 2003.
    • (2003) J Kor Med Sci , vol.18 , pp. 97-102
    • Lee, Y.M.1    Kim, S.S.2    Kim, H.A.3
  • 28
    • 38349137063 scopus 로고    scopus 로고
    • Effect of nerve growth factor and keratinocyte growth factor on wound healing of the sinus mucosa
    • Tan L, Hatzirodos N, and Wormald PJ. Effect of nerve growth factor and keratinocyte growth factor on wound healing of the sinus mucosa. Wound Repair Regen 16:108-116, 2008.
    • (2008) Wound Repair Regen , vol.16 , pp. 108-116
    • Tan, L.1    Hatzirodos, N.2    Wormald, P.J.3
  • 29
    • 0033429176 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides do not require TH1 cytokines to prevent eosinophilic airway inflammation in a murine model of asthma
    • Kline JN, Krieg AM, Waldschmidt TJ, et al. CpG oligodeoxynucleotides do not require TH1 cytokines to prevent eosinophilic airway inflammation in a murine model of asthma. J Allergy Clin Immunol 104:1258-1264, 1999.
    • (1999) J Allergy Clin Immunol , vol.104 , pp. 1258-1264
    • Kline, J.N.1    Krieg, A.M.2    Waldschmidt, T.J.3
  • 30
    • 33646232006 scopus 로고    scopus 로고
    • Altered expression of genes associated with innate immunity and inflammation in recalcitrant rhinosinusitis with polyps
    • Lane AP, Truong-Tran QA, and Schleimer RP. Altered expression of genes associated with innate immunity and inflammation in recalcitrant rhinosinusitis with polyps. Am J Rhinol 20:138-144, 2006.
    • (2006) Am J Rhinol , vol.20 , pp. 138-144
    • Lane, A.P.1    Truong-Tran, Q.A.2    Schleimer, R.P.3
  • 31
    • 17144403499 scopus 로고    scopus 로고
    • Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus
    • Wark PA, Johnston SL, Bucchieri F, et al. Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus. J Exp Med 201:937-947, 2005.
    • (2005) J Exp Med , vol.201 , pp. 937-947
    • Wark, P.A.1    Johnston, S.L.2    Bucchieri, F.3
  • 32
    • 36849045915 scopus 로고    scopus 로고
    • The inflammasome: A danger sensing complex triggering innate immunity
    • Petrilli V, Dostert C, Muruve DA, et al. The inflammasome: A danger sensing complex triggering innate immunity. Curr Opin Immunol 19:615-622, 2007.
    • (2007) Curr Opin Immunol , vol.19 , pp. 615-622
    • Petrilli, V.1    Dostert, C.2    Muruve, D.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.