-
1
-
-
0023617219
-
Multimodal action of antitumor agents on DNA: The ellipticine series
-
Auclair C. (1987). Multimodal action of antitumor agents on DNA: The ellipticine series. Arch Biochem Biophys 259: 1-14.
-
(1987)
Arch Biochem Biophys
, vol.259
, pp. 1-14
-
-
Auclair, C.1
-
2
-
-
0033194368
-
Expression analysis of multidrug resistance associated genes in neuroblastomas
-
Bader P, Schilling F, Schlaud M, Girgert R, Handgretinger R, Klingebiel T, Treuner J, Liu C, Niethammer D and Beck JF. (1999). Expression analysis of multidrug resistance associated genes in neuroblastomas. Onco. Rep 6: 1143-1146.
-
(1999)
Onco. Rep
, vol.6
, pp. 1143-1146
-
-
Bader, P.1
Schilling, F.2
Schlaud, M.3
Girgert, R.4
Handgretinger, R.5
Klingebiel, T.6
Treuner, J.7
Liu, C.8
Niethammer, D.9
Beck, J.F.10
-
3
-
-
0025826599
-
Expression of mdr-1/P-glycoprotein in human neuroblastoma
-
Bates SE, Shieh CY and Tsokos M. (1991). Expression of mdr-1/P-glycoprotein in human neuroblastoma. Am J Pathol 139: 305-315.
-
(1991)
Am J Pathol
, vol.139
, pp. 305-315
-
-
Bates, S.E.1
Shieh, C.Y.2
Tsokos, M.3
-
4
-
-
26044470519
-
Characterization of drug-resistant neuroblastoma cell lines by comparative genomic hybridization
-
Bedrnicek J, Vicha A, Jarosova M, Holzerova M, Cinatl J Jr, Michaelis M, Cinatl J and Eckschlager T. (2005). Characterization of drug-resistant neuroblastoma cell lines by comparative genomic hybridization. Neoplasma. 52: 415-419.
-
(2005)
Neoplasma
, vol.52
, pp. 415-419
-
-
Bedrnicek, J.1
Vicha, A.2
Jarosova, M.3
Holzerova, M.4
Cinatl Jr., J.5
Michaelis, M.6
Cinatl, J.7
Eckschlager, T.8
-
5
-
-
34249796391
-
Valproic acid inhibits adhesion of vincristine-and cisplatin-resistant neuroblastoma tumour cells to endothelium
-
Blaheta RA, Michaelis M, Natsheh I, Hasenberg C, Weich E, Relja B, Jonas D, Doerr HW and Cinatl J Jr. (2007). Valproic acid inhibits adhesion of vincristine-and cisplatin-resistant neuroblastoma tumour cells to endothelium. Br J Cancer 96: 1699-706.
-
(2007)
Br J Cancer
, vol.96
, pp. 1699-706
-
-
Blaheta, R.A.1
Michaelis, M.2
Natsheh, I.3
Hasenberg, C.4
Weich, E.5
Relja, B.6
Jonas, D.7
Doerr, H.W.8
Cinatl Jr., J.9
-
7
-
-
0037366067
-
Neuroblastoma: Biological insights into a clinical enigma
-
Brodeur GM. (2003). Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer 3: 203-216.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 203-216
-
-
Brodeur, G.M.1
-
8
-
-
33751505528
-
Valproic acid, a histone deacetylase inhibitor, enhances sensitivity to doxorubicin in anaplastic thyroid cancer cells
-
Catalano MG, Fortunati N, Pugliese M, Poli R, Bosco O, Mastrocola R, Aragno M and Boccuzzi G. (2006). Valproic acid, a histone deacetylase inhibitor, enhances sensitivity to doxorubicin in anaplastic thyroid cancer cells. J Endocrinol 191: 465-472.
-
(2006)
J Endocrinol
, vol.191
, pp. 465-472
-
-
Catalano, M.G.1
Fortunati, N.2
Pugliese, M.3
Poli, R.4
Bosco, O.5
Mastrocola, R.6
Aragno, M.7
Boccuzzi, G.8
-
9
-
-
49249098052
-
HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells
-
Chai G, Li L, Zhou W, Wu L, Zhao Y, Wang D, Lu S, Yu Y, Wang H, McNutt MA, Hu YG, Chen Y, Yang Y, Wu X, Otterson GA and Zhu WG. (2008). HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells. PLoS ONE 3: e2445.
-
(2008)
PLoS ONE
, vol.3
-
-
Chai, G.1
Li, L.2
Zhou, W.3
Wu, L.4
Zhao, Y.5
Wang, D.6
Lu, S.7
Yu, Y.8
Wang, H.9
McNutt, M.A.10
Hu, Y.G.11
Chen, Y.12
Yang, Y.13
Wu, X.14
Otterson, G.A.15
Zhu, W.G.16
-
10
-
-
0029909687
-
Antitumor activity of sodium valproate in cultures of human neuroblastoma cells
-
Cinatl J Jr, Cinatl J, Scholz M, Driever PH, Henrich D, Kabickova H, Vogel JU, Doerr HW and Kornhuber B. (1996). Antitumor activity of sodium valproate in cultures of human neuroblastoma cells. Anticancer Drugs 7: 766-773.
-
(1996)
Anticancer Drugs
, vol.7
, pp. 766-773
-
-
Cinatl Jr., J.1
Cinatl, J.2
Scholz, M.3
Driever, P.H.4
Henrich, D.5
Kabickova, H.6
Vogel, J.U.7
Doerr, H.W.8
Kornhuber, B.9
-
11
-
-
33846903310
-
Role of chemotherapy resistance genes in outcome of neuroblastoma 2007
-
de Cremoux P, Jourdan-Da-Silva N, Couturier J, Tran-Perennou C, Schleiermacher G, Fehlbaum P, Doz F, Mosseri V, Delattre O, Klijanienko J, Vielh P and Michon J. Role of chemotherapy resistance genes in outcome of neuroblastoma. (2007). Pediatr Blood Cancer 48: 311-317.
-
Pediatr Blood Cancer
, vol.48
, pp. 311-317
-
-
De Cremoux, P.1
Jourdan-Da-Silva, N.2
Couturier, J.3
Tran-Perennou, C.4
Schleiermacher, G.5
Fehlbaum, P.6
Doz, F.7
Mosseri, V.8
Delattre, O.9
Klijanienko, J.10
Vielh, P.11
Michon, J.12
-
12
-
-
0033093979
-
Antimitotic drugs cause increased tumorigenicity of multidrug resistant cells
-
Emanuel SL, Chamberlin HA and Cohen D. (1999). Antimitotic drugs cause increased tumorigenicity of multidrug resistant cells. Int J Oncol 14: 487-494.
-
(1999)
Int J Oncol
, vol.14
, pp. 487-494
-
-
Emanuel, S.L.1
Chamberlin, H.A.2
Cohen, D.3
-
13
-
-
0027104314
-
Stimulation of topoisomerase II-mediated DNA cleavage by ellipticine derivatives: Structure-activity relationships
-
FosśP, ReńB, Charra M, Paoletti C and Saucier JM (1992) Stimulation of topoisomerase II-mediated DNA cleavage by ellipticine derivatives: structure-activity relationships. Mol Pharmacol 42:590-595.
-
(1992)
Mol Pharmacol
, vol.42
, pp. 590-595
-
-
Fosś, P.1
Reń, B.2
Charra, M.3
Paoletti, C.4
Saucier, J.M.5
-
14
-
-
0029015354
-
Topoisomerase II binds to ellipticine in the absence or presence of DNA. Characterization of enzyme-drug interactions by fl uorescence spectroscopy
-
Froelich-Ammon SJ, Patchan MW, Osheroff N and Thompson RB. (1995). Topoisomerase II binds to ellipticine in the absence or presence of DNA. Characterization of enzyme-drug interactions by fl uorescence spectroscopy. J Biol Chem 270: 4998-5004.
-
(1995)
J Biol Chem
, vol.270
, pp. 4998-5004
-
-
Froelich-Ammon, S.J.1
Patchan, M.W.2
Osheroff, N.3
Thompson, R.B.4
-
15
-
-
33947153003
-
Inhibitors of histone deacetylases as potential therapeutic tools for high-risk embryonal tumors of the nervous system of childhood
-
Furchert SE, Lanvers-Kaminsky C, Júgens H, Jung M, Loidl A and Fŕwald MC. (2007). Inhibitors of histone deacetylases as potential therapeutic tools for high-risk embryonal tumors of the nervous system of childhood. Int J Cancer 120: 1787-1794.
-
(2007)
Int J Cancer
, vol.120
, pp. 1787-1794
-
-
Furchert, S.E.1
Lanvers-Kaminsky, C.2
Júgens, H.3
Jung, M.4
Loidl, A.5
Fŕwald, M.C.6
-
16
-
-
52949150776
-
Reduction of doxorubicin and oracin and induction of carbonyl reductase in human breast carcinoma MCF-7 cells
-
GavelováM, HlaďováJ, VildováL, NovotńR, Vondŕek J, Krcm P, Machala M and Sǩová L(2008) Reduction of doxorubicin and oracin and induction of carbonyl reductase in human breast carcinoma MCF-7 cells. Chem Biol Interact 176:9-18.
-
(2008)
Chem Biol Interact
, vol.176
, pp. 9-18
-
-
Gavelová, M.1
Hlaďová, J.2
Vildová, L.3
Novotń, R.4
Vondŕek, J.5
Krcm, P.6
MacHala, M.7
Sǩová, L.8
-
17
-
-
0037026635
-
Doxorubicin-induced death in neuroblastoma does not involve death receptors in S-type cells and is caspase-independent in N-type cells
-
Hopkins-Donaldson S, Yan P, Bourloud KB, Muhlethaler A, Bodmer JL and Gross N. (2002). Doxorubicin-induced death in neuroblastoma does not involve death receptors in S-type cells and is caspase-independent in N-type cells. Oncogene 21: 6132-37.
-
(2002)
Oncogene
, vol.21
, pp. 6132-6137
-
-
Hopkins-Donaldson, S.1
Yan, P.2
Bourloud, K.B.3
Muhlethaler, A.4
Bodmer, J.L.5
Gross, N.6
-
18
-
-
13944280578
-
Effects of suberoylanilide hydroxamic acid and trichostatin A on induction of cytochrome P450 enzymes and benzo[a] pyrene DNA adduct formation in human cells
-
Hooven LA, Mahadevan B, Keshava C, Johns C, Pereira C, Desai D, Amin S, Weston A and Baird WM. (2005). Effects of suberoylanilide hydroxamic acid and trichostatin A on induction of cytochrome P450 enzymes and benzo[a] pyrene DNA adduct formation in human cells. Bioorg Med Chem Lett 15: 1283-1287
-
(2005)
Bioorg Med Chem Lett
, vol.15
, pp. 1283-1287
-
-
Hooven, L.A.1
Mahadevan, B.2
Keshava, C.3
Johns, C.4
Pereira, C.5
Desai, D.6
Amin, S.7
Weston, A.8
Baird, W.M.9
-
19
-
-
77956329493
-
Histone deacetylase inhibitors valproate and trichostatin A are toxic to neuroblastoma cells and modulate cytochrome P450 1A1, 1B1 and 3A4 expression in these cells
-
HÝebǎkováJ, PoljakováJ, Eckschlager T, Hrabta J, Prochýka P, Smutń S and StiborováM. (2009). Histone deacetylase inhibitors valproate and trichostatin A are toxic to neuroblastoma cells and modulate cytochrome P450 1A1, 1B1 and 3A4 expression in these cells. Interdisc Toxicol 2: 205-210.
-
(2009)
Interdisc Toxicol
, vol.2
, pp. 205-210
-
-
Hýebǎková, J.1
Poljaková, J.2
Eckschlager, T.3
Hrabta, J.4
Prochýka, P.5
Smutń, S.6
Stiborová, M.7
-
20
-
-
0242610850
-
Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA
-
Kim MS, Blake M, Baek JH, Kohlhagen G, Pommier Y and Carrier F. (2003). Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA. Cancer Res 63: 7291-7300.
-
(2003)
Cancer Res
, vol.63
, pp. 7291-7300
-
-
Kim, M.S.1
Blake, M.2
Baek, J.H.3
Kohlhagen, G.4
Pommier, Y.5
Carrier, F.6
-
22
-
-
28144451848
-
Increased malignant behavior in neuroblastoma cells with acquired multi-drug resistance does not depend on P-gp expression
-
Kotchetkov R, Driever PH, Cinatl J, Michaelis M, Karaskova J, Blaheta R, Squire JA, Von Deimling A, Moog J and Cinatl J Jr. (2005). Increased malignant behavior in neuroblastoma cells with acquired multi-drug resistance does not depend on P-gp expression. Int J Oncol 27: 1029-1037.
-
(2005)
Int J Oncol
, vol.27
, pp. 1029-1037
-
-
Kotchetkov, R.1
Driever, P.H.2
Cinatl, J.3
Michaelis, M.4
Karaskova, J.5
Blaheta, R.6
Squire, J.A.7
Von Deimling, A.8
Moog, J.9
Cinatl Jr., J.10
-
23
-
-
0035713318
-
Signifi cance of P-glycoprotein expression in childhood malignant tumors
-
Kucerova H, Sumerauer D, Drahokoupilova E, Piskova M, Bedrnicek J and Eckschlager T. (2001). Signifi cance of P-glycoprotein expression in childhood malignant tumors. Neoplasma 48: 472-478.
-
(2001)
Neoplasma
, vol.48
, pp. 472-478
-
-
Kucerova, H.1
Sumerauer, D.2
Drahokoupilova, E.3
Piskova, M.4
Bedrnicek, J.5
Eckschlager, T.6
-
24
-
-
0031791723
-
Presence of classical multidrug resistance and P-glycoprotein expression in human neuroblastoma cells
-
Kurowski C and Berthold F. (1998). Presence of classical multidrug resistance and P-glycoprotein expression in human neuroblastoma cells. Ann Oncol 9: 1009-1014.
-
(1998)
Ann Oncol
, vol.9
, pp. 1009-1014
-
-
Kurowski, C.1
Berthold, F.2
-
25
-
-
77950815766
-
Pharmacogenetics of target genes across doxorubicin disposition pathway: A review
-
Lal S, Mahajan A, Chen WN and Chowbay B. (2010). Pharmacogenetics of target genes across doxorubicin disposition pathway: a review. Curr Drug Metab 11: 115-128.
-
(2010)
Curr Drug Metab
, vol.11
, pp. 115-128
-
-
Lal, S.1
Mahajan, A.2
Chen, W.N.3
Chowbay, B.4
-
26
-
-
41849091539
-
TP53, BCL-2, p21Waf1/Cip1 and metallothionein as markers of diff erentiation, response to treatment and prognosis in neuroblastic tumors
-
Lara-Bohýquez C, Gonźez-Ćpora R, Mendoza-Gaŕc E, R̂s-Mart JJ, Pareja-Megi MJ and LÍez-Beltŕ A. (2008). TP53, BCL-2, p21Waf1/Cip1 and metallothionein as markers of diff erentiation, response to treatment and prognosis in neuroblastic tumors. Anal. Quant Cytol Histol 30: 105-112.
-
(2008)
Anal. Quant Cytol Histol
, vol.30
, pp. 105-112
-
-
Lara-Bohýquez, C.1
Gonźez-Ćpora, R.2
Mendoza-Gaŕc, E.3
R̂s-Mart, J.J.4
Pareja-Megi, M.J.5
Líez-Beltŕ, A.6
-
27
-
-
18144373452
-
Valproic acid alters chromatin structure by regulation of chromatin modulation proteins
-
Marchion DC, Bicaku E, Daud AI, Sullivan DM and Munster PN. (2005a) Valproic acid alters chromatin structure by regulation of chromatin modulation proteins. Cancer Res 65: 3815-3822.
-
(2005)
Cancer Res
, vol.65
, pp. 3815-3822
-
-
Marchion, D.C.1
Bicaku, E.2
Daud, A.I.3
Sullivan, D.M.4
Munster, P.N.5
-
28
-
-
30344443991
-
In vivo synergy between topoisomerase II and histone deacetylase inhibitors: Predictive correlates
-
Marchion DC, Bicaku E, Daud AI, Sullivan DM and Munster PN. (2005b) In vivo synergy between topoisomerase II and histone deacetylase inhibitors: predictive correlates. Mol. Cancer Ther 4: 1993-2000.
-
(2005)
Mol. Cancer Ther
, vol.4
, pp. 1993-2000
-
-
Marchion, D.C.1
Bicaku, E.2
Daud, A.I.3
Sullivan, D.M.4
Munster, P.N.5
-
29
-
-
0033034390
-
Molecular biology of neuroblastoma
-
Maris JM and Matthay KK. (1999). Molecular biology of neuroblastoma. J Clin Oncol 17: 2264-2279.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2264-2279
-
-
Maris, J.M.1
Matthay, K.K.2
-
33
-
-
0025789701
-
Cutaneous NAD(P)H: Quinone reductase: A xenobiotica-metabolizing enzyme with potential cancer and oxidation stress-protecting properties
-
Merk HF and Jugert FK. (1991). Cutaneous NAD(P)H: quinone reductase: a xenobiotica-metabolizing enzyme with potential cancer and oxidation stress-protecting properties. Skin Pharmacol 4 Suppl 1: 95-100.
-
(1991)
Skin Pharmacol
, vol.4
, Issue.SUPPL. 1
, pp. 95-100
-
-
Merk, H.F.1
Jugert, F.K.2
-
34
-
-
16644379041
-
Valproic acid and interferon-alpha synergistically inhibit neuroblastoma cell growth in vitro and in vivo
-
Michaelis M, Suhan T, Cinatl J, Driever PH and Cinatl J Jr. (2004). Valproic acid and interferon-alpha synergistically inhibit neuroblastoma cell growth in vitro and in vivo. Int J Oncol 25: 1795-1799.
-
(2004)
Int J Oncol
, vol.25
, pp. 1795-1799
-
-
Michaelis, M.1
Suhan, T.2
Cinatl, J.3
Driever, P.H.4
Cinatl Jr., J.5
-
36
-
-
0026011643
-
DNA-drug recognition and effects on topoisomerase II-mediated cytotoxicity. A three-mode binding model for ellipticine derivatives
-
Monnot M, Mauff ret O, Simon V, Lescot E, Psaume B, Saucier JM, Charra M, Belehradek J Jr and Fermandjian S. (1991). DNA-drug recognition and effects on topoisomerase II-mediated cytotoxicity. A three-mode binding model for ellipticine derivatives. J Biol Chem 25: 1820-1829.
-
(1991)
J Biol Chem
, vol.25
, pp. 1820-1829
-
-
Monnot, M.1
Mauff Ret, O.2
Simon, V.3
Lescot, E.4
Psaume, B.5
Saucier, J.M.6
Charra, M.7
Belehradek Jr., J.8
Fermandjian, S.9
-
38
-
-
0030031845
-
Expression of the gene for multidrug-resistance-associated protein and outcome in patients with neuroblastoma
-
Norris MD, Bordow SB, Marshall GM, Haber PS, Cohn SL and Haber M. (1996). Expression of the gene for multidrug-resistance-associated protein and outcome in patients with neuroblastoma. N Engl J Med 334: 231-238.
-
(1996)
N Engl J Med
, vol.334
, pp. 231-238
-
-
Norris, M.D.1
Bordow, S.B.2
Marshall, G.M.3
Haber, P.S.4
Cohn, S.L.5
Haber, M.6
-
39
-
-
1042302133
-
Modulation of mutagenicity by phosphorylation of mutagen-metabolizing enzymes
-
Oesch-Bartlmowicz B and Oesch F. (2004 ) Modulation of mutagenicity by phosphorylation of mutagen-metabolizing enzymes. Arch Biochem Biophys 423: 31-36.
-
(2004)
Arch Biochem Biophys
, vol.423
, pp. 31-36
-
-
Oesch-Bartlmowicz, B.1
Oesch, F.2
-
40
-
-
0032513236
-
The binding properties and biological activities of Bcl-2 and Bax in cells exposed to apoptotic stimuli
-
Otter I, Conus S, Ravn U, Rager M, Olivier R, Monney L, Fabbro D and Borner C. (1998). The binding properties and biological activities of Bcl-2 and Bax in cells exposed to apoptotic stimuli. J Biol Chem 273: 6110-6120.
-
(1998)
J Biol Chem
, vol.273
, pp. 6110-6120
-
-
Otter, I.1
Conus, S.2
Ravn, U.3
Rager, M.4
Olivier, R.5
Monney, L.6
Fabbro, D.7
Borner, C.8
-
41
-
-
0035900820
-
MRP1 gene expression level regulates the death and diff erentiation response of neuroblastoma cells
-
Peaston AE, Gardaneh M, Franco AV, Hocker JE, Murphy KM, Farnsworth ML, Catchpoole DR, Haber M, Norris MD, Lock RB and Marshall GM. (2001). MRP1 gene expression level regulates the death and diff erentiation response of neuroblastoma cells. Br J Cancer 85: 1564-1571.
-
(2001)
Br J Cancer
, vol.85
, pp. 1564-1571
-
-
Peaston, A.E.1
Gardaneh, M.2
Franco, A.V.3
Hocker, J.E.4
Murphy, K.M.5
Farnsworth, M.L.6
Catchpoole, D.R.7
Haber, M.8
Norris, M.D.9
Lock, R.B.10
Marshall, G.M.11
-
42
-
-
77956325035
-
The comparison of cytotoxicity of anticancer drug doxorubicin and ellipticine to human neuroblastoma cells
-
PoljakováJ, Eckschlager T, HÝebǎkováJ, Hrabta J and StiborováM. (2008). The comparison of cytotoxicity of anticancer drug doxorubicin and ellipticine to human neuroblastoma cells. Interdisc Toxicol 1: 186-189.
-
(2008)
Interdisc Toxicol
, vol.1
, pp. 186-189
-
-
Poljaková, J.1
Eckschlager, T.2
Hýebǎková, J.3
Hrabta, J.4
Stiborová, M.5
-
43
-
-
63149114184
-
The mechanism of cytotoxicity and DNA adduct formation by the anticancer drug ellipticine in human neuroblastoma cells
-
Poljakova J, Eckschlager T, Hrabeta J, Hrebackova J, Smutny S, Frei E, Martinek V, Kizek R and Stiborova M. (2009). The mechanism of cytotoxicity and DNA adduct formation by the anticancer drug ellipticine in human neuroblastoma cells. Biochem Pharmacol 77: 1466-1479.
-
(2009)
Biochem Pharmacol
, vol.77
, pp. 1466-1479
-
-
Poljakova, J.1
Eckschlager, T.2
Hrabeta, J.3
Hrebackova, J.4
Smutny, S.5
Frei, E.6
Martinek, V.7
Kizek, R.8
Stiborova, M.9
-
44
-
-
34249033131
-
Histone deacetylase inhibitors: Molecular and biological activity as a premise to clinical application
-
Santini V, Gozzini A and Ferrari G. (2007). Histone deacetylase inhibitors: molecular and biological activity as a premise to clinical application. Curr Drug Metab 8: 383-393.
-
(2007)
Curr Drug Metab
, vol.8
, pp. 383-393
-
-
Santini, V.1
Gozzini, A.2
Ferrari, G.3
-
45
-
-
0027953894
-
Highfi eld NMR and restrained molecular modeling studies on a DNA heteroduplex containing a modifi ed apurinic abasic site in the form of covalently linked 9-aminoellipticine
-
Singh MP, Hill GC, Peoch D, Rayner B, Inabach JL and Lown JW. (1994). Highfi eld NMR and restrained molecular modeling studies on a DNA heteroduplex containing a modifi ed apurinic abasic site in the form of covalently linked 9-aminoellipticine. Biochemistry 33: 10271-10285.
-
(1994)
Biochemistry
, vol.33
, pp. 10271-10285
-
-
Singh, M.P.1
Hill, G.C.2
Peoch, D.3
Rayner, B.4
Inabach, J.L.5
Lown, J.W.6
-
46
-
-
33748458071
-
Hypoxia-induced resistance to cisplatin and doxorubicin in non-small cell lung cancer is inhibited by silencing of HIF-1alpha gene
-
Song X, Liu X, Chi W, Liu Y, Wei L, Wang X and Yu J. (2006). Hypoxia-induced resistance to cisplatin and doxorubicin in non-small cell lung cancer is inhibited by silencing of HIF-1alpha gene. Cancer Chemother Pharmacol 58: 776-784.
-
(2006)
Cancer Chemother Pharmacol
, vol.58
, pp. 776-784
-
-
Song, X.1
Liu, X.2
Chi, W.3
Liu, Y.4
Wei, L.5
Wang, X.6
Yu, J.7
-
47
-
-
0035894174
-
The anticancer agent ellipticine on activation by cytochrome P450 forms covalent DNA adducts
-
StiborováM, Bieler CA, Wiessler M and Frei E. (2001). The anticancer agent ellipticine on activation by cytochrome P450 forms covalent DNA adducts. Biochem Pharmacol 62: 675-684.
-
(2001)
Biochem Pharmacol
, vol.62
, pp. 675-684
-
-
Stiborová, M.1
Bieler, C.A.2
Wiessler, M.3
Frei, E.4
-
48
-
-
0242425937
-
DNA adduct formation by the anticancer drug ellipticine in rats determined by 32P-postlabeling
-
StiborováM, Breuer A, AimováD, Stiborová RupertováM, Wiessler M and Frei E. (2003a) DNA adduct formation by the anticancer drug ellipticine in rats determined by 32P-postlabeling. Int J Cancer 107: 885-890.
-
(2003)
Int J Cancer
, vol.107
, pp. 885-890
-
-
Stiborová, M.1
Breuer, A.2
Aimová, D.3
Stiborová rupertová, M.4
Wiessler, M.5
Frei, E.6
-
49
-
-
12244292673
-
Rat microsomes activating the anticancer drug ellipticine to species covalently binding to deoxyguanosine in DNA are a suitable model mimicking ellipticine bioactivation in humans
-
StiborováM, StiborováRupertováM, Bǒek-DohalskL, Wiessler M, Frei E(2003b) Rat microsomes activating the anticancer drug ellipticine to species covalently binding to deoxyguanosine in DNA are a suitable model mimicking ellipticine bioactivation in humans. Chem Res Toxicol 16:38-47.
-
(2003)
Chem Res Toxicol
, vol.16
, pp. 38-47
-
-
Stiborová, M.1
Stiborovárupertová, M.2
Bǒek-Dohalsk, L.3
Wiessler, M.4
Frei, E.5
-
50
-
-
8644288137
-
The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N2-oxide
-
StiborováM, Sejbal J, Bǒek-DohalskL, AimováD, PoljakováJ, ForsterováK, RupertováM, Wiesner J, Hudéek J, Wiessler M and Frei E(2004) The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N2-oxide. Cancer Res 64:8374-8380.
-
(2004)
Cancer Res
, vol.64
, pp. 8374-8380
-
-
Stiborová, M.1
Sejbal, J.2
Bǒek-Dohalsk, L.3
Aimová, D.4
Poljaková, J.5
Forsterová, K.6
Rupertová, M.7
Wiesner, J.8
Hudéek, J.9
Wiessler, M.10
Frei, E.11
-
52
-
-
33845624680
-
Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine
-
StiborováM, PoljakováJ, RyŝlaváH, Drǎ̂sk M, Eckschlager T and Frei E. (2007a) Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine. Int J Cancer 120: 243-251.
-
(2007)
Int J Cancer
, vol.120
, pp. 243-251
-
-
Stiborová, M.1
Poljaková, J.2
Ryŝlavá, H.3
Drǎ̂sk, M.4
Eckschlager, T.5
Frei, E.6
-
53
-
-
34248652696
-
Formation and persistence of DNA adducts of anticancer drug ellipticine in rats
-
StiborováM, RupertováM, AimováD, RyŝlaváH and Frei E. (2007b) Formation and persistence of DNA adducts of anticancer drug ellipticine in rats. Toxicology 236: 50-60.
-
(2007)
Toxicology
, vol.236
, pp. 50-60
-
-
Stiborová, M.1
Rupertová, M.2
Aimová, D.3
Ryŝlavá, H.4
Frei, E.5
-
54
-
-
38649108546
-
Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH: Cytochrome P450 reductase null mouse
-
StiborováM, Arlt VM, Henderson CJ, Wolf CR, KotrbováV, MoserováM, Hudéek J, Phillips DH and Frei E. (2008). Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: studies with the hepatic NADPH: cytochrome P450 reductase null mouse. Toxicol Appl Pharmacol 226: 318-327.
-
(2008)
Toxicol Appl Pharmacol
, vol.226
, pp. 318-327
-
-
Stiborová, M.1
Arlt, V.M.2
Henderson, C.J.3
Wolf, C.R.4
Kotrbová, V.5
Moserová, M.6
Hudéek, J.7
Phillips, D.H.8
Frei, E.9
-
55
-
-
77956298408
-
Cytochrome P450- and peroxidase-mediated oxidation of anticancer alkaloid ellipticine dictates its antitumor effi ciency
-
in press
-
StiborováM, RupertováM and Frei E. (2010). Cytochrome P450- and peroxidase-mediated oxidation of anticancer alkaloid ellipticine dictates its antitumor effi ciency. Biochim Biophys Acta, in press.
-
(2010)
Biochim Biophys Acta
-
-
Stiborová, M.1
Rupertová, M.2
Frei, E.3
-
56
-
-
0033039024
-
Human neuroblastoma: From basic science to clinical debut of cellular oncogenes
-
Schwab M. (1999). Human neuroblastoma: from basic science to clinical debut of cellular oncogenes. Naturwissenschaften 86: 71-78.
-
(1999)
Naturwissenschaften
, vol.86
, pp. 71-78
-
-
Schwab, M.1
-
57
-
-
33745561038
-
Morphological and molecular assessment of apoptotic mechanisms in peripheral neuroblastic tumours
-
Uccini S, Colarossi C, Scarpino S, Boldrini R, Natali PG, Nicotra MR, Perla FM, Mannarino O, Altavista P, Boglino C, Cappelli CA, Cozzi D, Donfrancesco A, Kokai G, Losty PD, McDowell HP and Dominici C. (2006). Morphological and molecular assessment of apoptotic mechanisms in peripheral neuroblastic tumours. Br J Cancer 95: 49-55
-
(2006)
Br J Cancer
, vol.95
, pp. 49-55
-
-
Uccini, S.1
Colarossi, C.2
Scarpino, S.3
Boldrini, R.4
Natali, P.G.5
Nicotra, M.R.6
Perla, F.M.7
Mannarino, O.8
Altavista, P.9
Boglino, C.10
Cappelli, C.A.11
Cozzi, D.12
Donfrancesco, A.13
Kokai, G.14
Losty, P.D.15
McDowell, H.P.16
Dominici, C.17
-
58
-
-
31544446626
-
Cancer treatment and pharmacogenetics of cytochrome P450 enzymes
-
van Schaik R. (2005). Cancer treatment and pharmacogenetics of cytochrome P450 enzymes. Invest New Drugs 23: 513-522.
-
(2005)
Invest New Drugs
, vol.23
, pp. 513-522
-
-
Van Schaik, R.1
-
59
-
-
46149095280
-
CYP450 pharmacogenetics for personalizing cancer therapy
-
van Schaik RH. (2008). CYP450 pharmacogenetics for personalizing cancer therapy. Drug Resist Updat 11: 77-98
-
(2008)
Drug Resist Updat
, vol.11
, pp. 77-98
-
-
Van Schaik, R.H.1
-
60
-
-
31844434762
-
Diff erentiation, proliferation and adhesion of human neuroblastoma cells after treatment with retinoic acid
-
Voigt A, Hartmann P and Zintl F. (2000). Diff erentiation, proliferation and adhesion of human neuroblastoma cells after treatment with retinoic acid. Cell Adhes Commun 7: 423-440.
-
(2000)
Cell Adhes Commun
, vol.7
, pp. 423-440
-
-
Voigt, A.1
Hartmann, P.2
Zintl, F.3
-
61
-
-
52449133102
-
CYP2B6: New insights into a historically overlooked cytochrome P450 isozyme
-
Wang H and Tompkins L. (2008). CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme. Curr Drug Metab 9: 598-610.
-
(2008)
Curr Drug Metab
, vol.9
, pp. 598-610
-
-
Wang, H.1
Tompkins, L.2
-
62
-
-
0037190798
-
Genetic parameters of neuroblastomas
-
Westermann F and Schwab M. (2002). Genetic parameters of neuroblastomas. Cancer Lett 184: 127-147.
-
(2002)
Cancer Lett
, vol.184
, pp. 127-147
-
-
Westermann, F.1
Schwab, M.2
-
63
-
-
64249143717
-
Targeting histone deacetylases in neuroblastoma
-
Witt O, Deubzer HE, Lodrini M, Milde T and Oehme I. (2009). Targeting histone deacetylases in neuroblastoma. Curr Pharm Des 15: 436-447.
-
(2009)
Curr Pharm des
, vol.15
, pp. 436-447
-
-
Witt, O.1
Deubzer, H.E.2
Lodrini, M.3
Milde, T.4
Oehme, I.5
-
64
-
-
0037276902
-
The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells
-
Zhu WG and Otterson GA. (2003). The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells. Curr Med Chem Anticancer Agents 3: 187-199.
-
(2003)
Curr Med Chem Anticancer Agents
, vol.3
, pp. 187-199
-
-
Zhu, W.G.1
Otterson, G.A.2
|