Induction of heme oxygenase-1, biliverdin reductase and h-ferritin in lung macrophage in smokers with primary spontaneous pneumothorax: Role of hif-1α

PLoS ONE

Volumn 5, Issue 5, 2010, Pages

  Goven, Delphine ^a   Boutten, Anne ^a   Leçon Malas, Véronique ^a,b   Marchal Sommé, Joëlle ^b   Soler, Paul ^a   Boczkowski, Jorge ^a,c,d   Bonay, Marcel ^a,b  

^a INSERM   (France)

^b BICHAT HOSPITAL   (France)

^c Centre d'Investigation Clinique   (France)

^d FACULTÉ DE MÉDECINE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; BILIVERDIN REDUCTASE; FERRITIN; HEAVY CHAIN FERRITIN; HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; OXIDOREDUCTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; APOFERRITIN; CD68 ANTIGEN, HUMAN; DIFFERENTIATION ANTIGEN; LEUKOCYTE ANTIGEN; OXYGEN; PLASMA PROTEIN; PRG2 PROTEIN, HUMAN; PROTEOGLYCAN; REACTIVE OXYGEN METABOLITE;

ARTICLE; CELL HYPOXIA; CELLULAR DISTRIBUTION; CELLULAR STRESS SIGNAL; CIGARETTE SMOKING; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENZYME INDUCTION; GENE EXPRESSION REGULATION; GENE SILENCING; GENE TRANSLOCATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTRACELLULAR TRANSPORT; LUNG ALVEOLUS MACROPHAGE; LUNG BIOPSY; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS REGULATION; RECURRENCE RISK; REOXYGENATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK FACTOR; SMOKING HABIT; SPONTANEOUS PNEUMOTHORAX; TRANSCRIPTION REGULATION; UPREGULATION; WESTERN BLOTTING; BIOPSY; BIOSYNTHESIS; CELL LINE; ENZYMOLOGY; GENETICS; LUNG; MACROPHAGE; METABOLISM; PATHOLOGY; PNEUMOTHORAX; SMOKING;

ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; APOFERRITINS; BIOPSY; BLOOD PROTEINS; CELL HYPOXIA; CELL LINE; ENZYME INDUCTION; GENE EXPRESSION REGULATION; GENE SILENCING; HEME OXYGENASE-1; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LUNG; MACROPHAGES; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; OXYGEN; PNEUMOTHORAX; PROTEOGLYCANS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SMOKING;

EID: 77956283252     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010886     Document Type: Article

References (39)

1. Sahn SA, Heffner JE (2000) Spontaneous pneumothorax. N Engl J Med 342: 868-874.
2. Schramel FM, Postmus PE, Vanderschueren RG (1997) Current aspects of spontaneous pneumothorax. Eur Respir J 10: 1372-1379.
3. Bense L, Eklund G, Wiman LG (1987) Smoking and the increased risk of contracting spontaneous pneumothorax. Chest 92: 1009-1012.
4. Lippert HL, Lund O, Blegvad S, Larsen HV (1991) Independent risk factors for cumulative recurrence rate after first spontaneous pneumothorax. Eur Respir J 4: 324-331.
5. De Smedt A, Vanderlinden E, Demanet C, De Waele M, Goossens A, et al. (2004) Characterisation of pleural inflammation occurring after primary spontaneous pneumothorax. Eur Respir J 23: 896-900.
6. Pryor WA, Stone K (1993) Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite. Ann N Y Acad Sci 686: 12-27; discussion 27-18.
7. Rahman I, Biswas SK, Kode A (2006) Oxidant and antioxidant balance in the airways and airway diseases. Eur J Pharmacol 533: 222-239.
8. Ciencewicki J, Trivedi S, Kleeberger SR (2008) Oxidants and the pathogenesis of lung diseases. J Allergy Clin Immunol 122: 456-468; quiz 469-470.
9. Goven D, Boutten A, Lecon-Malas V, Marchal-Somme J, Amara N, et al. (2008) Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema. Thorax 63: 916-924.
10. Goven D, Boutten A, Lecon-Malas V, Boczkowski J, Bonay M (2009) Prolonged cigarette smoke exposure decreases heme oxygenase-1 and alters Nrf2 and Bach1 expression in human macrophages: roles of the MAP kinases ERK(1/2) and JNK. FEBS Lett 583: 3508-3518.
11. Fredenburgh LE, Perrella MA, Mitsialis SA (2007) The role of heme oxygenase-1 in pulmonary disease. Am J Respir Cell Mol Biol 36: 158-165.
12. Subotic D, Mandaric D, Gajic M, Vukcevic M (2005) Uncertainties in the current understanding of gas exchange in spontaneous pneumothorax: effective lung ventilation may persist in a smaller-sized pneumothorax. Med Hypotheses 64: 1144-1149.
13. Walmsley SR, McGovern NN, Whyte MK, Chilvers ER (2008) The HIF/VHL pathway: from oxygen sensing to innate immunity. Am J Respir Cell Mol Biol 38: 251-255.
14. Kensler TW, Wakabayashi N, Biswal S (2007) Cell Survival Responses to Environmental Stresses Via the Keap1-Nrf2-ARE Pathway. Annu Rev Pharmacol Toxicol 47: 89-116.
15. Rahman I, van Schadewijk AA, Crowther AJ, Hiemstra PS, Stolk J, MacNee, et al. (2002) 4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 166: 490-495.
16. Cottin V, Streichenberger N, Gamondes JP, Thevenet F, Loire R, et al. (1998) Respiratory bronchiolitis in smokers with spontaneous pneumothorax. Eur Respir J 12: 702-704.
17. Tabakoglu E, Ciftci S, Hatipoglu ON, Altiay G, Caglar T (2004) Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax. Mediators Inflamm 13: 209-210.
18. Smit HJ, van den Heuvel MM, Barbierato SB, Beelen RJ, Postmus PE (1999) Analysis of pleural fluid in idiopathic spontaneous pneumothorax; correlation of eosinophil percentage with the duration of air in the pleural space. Respir Med 93: 262-267.
19. Otterbein LE, Kolls JK, Mantell LL, Cook JL, Alam J, et al. (1999) Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury. J Clin Invest 103: 1047-1054.
20. Hashiba T, Suzuki M, Nagashima Y, Suzuki S, Inoue S, et al. (2001) Adenovirus-mediated transfer of heme oxygenase-1 cDNA attenuates severe lung injury induced by the influenza virus in mice. Gene Ther 8: 1499-1507.
21. Hisada T, Salmon M, Nasuhara Y, Chung KF (2000) Involvement of haemoxygenase-1 in ozone-induced airway inflammation and hyperresponsiveness. Eur J Pharmacol 399: 229-234.
22. Jia YX, Sekizawa K, Okinaga S, Lie R, Sasaki H (1999) Role of heme oxygenase in pulmonary response to antigen challenge in sensitized rats in vivo. Int Arch Allergy Immunol 120: 141-145.
23. Pachori AS, Smith A, McDonald P, Zhang L, Dzau VJ, et al. (2007) Hemeoxygenase-1-induced protection against hypoxia/reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway. J Mol Cell Cardiol 43: 580-592.
24. Berberat PO, Katori M, Kaczmarek E, Anselmo D, Lassman C, et al. (2003) Heavy chain ferritin acts as an antiapoptotic gene that protects livers from ischemia reperfusion injury. Faseb J 17: 1724-1726.
25. Maestrelli P, El Messlemani AH, De Fina O, Nowicki Y, Saetta M, et al. (2001) Increased expression of heme oxygenase (HO)-1 in alveolar spaces and HO-2 in alveolar walls of smokers. Am J Respir Crit Care Med 164: 1508-1513.
26. Atzori L, Caramori G, Lim S, Jazrawi E, Donnelly L, et al. (2004) Effect of cigarette smoking on haem-oxygenase expression in alveolar macrophages. Respir Med 98: 530-535.
27. Lee PJ, Jiang BH, Chin BY, Iyer NV, Alam J, et al. (1997) Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia. J Biol Chem 272: 5375-5381.
28. Ning XH, Chen SH, Buroker NE, Xu CS, Li FR, et al. (2007) Short-cycle hypoxia in the intact heart: hypoxia-inducible factor 1alpha signaling and the relationship to injury threshold. Am J Physiol Heart Circ Physiol 292: H333-H341.
29. Li B, Takeda K, Yokoyama S, Shibahara S (2008) A prolyl-hydroxylase inhibitor, ethyl-3,4-dihydroxybenzoate, induces haem oxygenase-1 expression in human cells through a mechanism independent of hypoxia-inducible factor-1alpha. J Biochem 144: 643-654.
30. Knowles HJ, Mole DR, Ratcliffe PJ, Harris AL (2006) Normoxic stabilization of hypoxia-inducible factor-1alpha by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1. Cancer Res 66: 2600-2607.
31. Bouvry D, Planes C, Malbert-Colas L, Escabasse V, Clerici C (2006) Hypoxiainduced cytoskeleton disruption in alveolar epithelial cells. Am J Respir Cell Mol Biol 35: 519-527.
32. Zeng R, Yao Y, Han M, Zhao X, Liu XC, et al. (2008) Biliverdin reductase mediates hypoxia-induced EMT via PI3-kinase and Akt. J Am Soc Nephrol 19:380-387.
33. Lee DW, Andersen JK (2006) Role of HIF-1 in iron regulation: potential therapeutic strategy for neurodegenerative disorders. Curr Mol Med 6: 883-893.
34. Malhotra D, Thimmulappa R, Navas-Acien A, Sandford A, Elliott M, et al. (2008) Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1. Am J Respir Crit Care Med 178: 592-604.
35. Boutten A, Goven D, Boczkowski J, Bonay M (2010) Oxidative stress targets in pulmonary emphysema: focus on the Nrf2 pathway. Expert Opin Ther Targets 14: 329-346.
36. Bonay M, Boutten A, Lecon-Malas V, Marchal J, Soler P, et al. (2005) Hepatocyte and keratinocyte growth factors and their receptors in human lung emphysema. BMC Pulm Med 5: 13.
37. Fields WR, Leonard RM, Odom PS, Nordskog BK, Ogden MW, et al. (2005) Gene expression in normal human bronchial epithelial (NHBE) cells following in vitro exposure to cigarette smoke condensate. Toxicol Sci 86: 84-91.
38. Molliex S, Crestani B, Dureuil B, Bastin J, Rolland C, et al. (1994) Effects of halothane on surfactant biosynthesis by rat alveolar type II cells in primary culture. Anesthesiology 81: 668-676.
39. Amara N, Bachoual R, Desmard M, Golda S, Guichard C, et al. (2007) Diesel exhaust particles induce matrix metalloprotease-1 in human lung epithelial cells via a NADP(H) oxidase/NOX4 redox-dependent mechanism. Am J Physiol Lung Cell Mol Physiol 293: L170-L181