Involvement of haemoxygenase-1 in ozone-induced airway inflammation and hyperresponsiveness

European Journal of Pharmacology

Volumn 399, Issue 2-3, 2000, Pages 229-234

  Hisada, Takeshi ^a   Salmon, Michael ^a   Nasuhara, Yasuyuki ^a   Chung, K Fan ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Bronchial hyperresponsiveness; Carbon monoxide (CO); Haemoxygenase; Neutrophil; Ozone

Indexed keywords

ANTIOXIDANT; CARBON MONOXIDE; HEMOGLOBIN; HEMOXYGENASE 1; OZONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; MALE; NEUTROPHILIA; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ACETYLCHOLINE; ANIMALS; BRONCHIAL HYPERREACTIVITY; BRONCHITIS; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; ENZYME INHIBITORS; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; HEMOGLOBINS; LUNG; MALE; METALLOPORPHYRINS; NEUTROPHILS; OZONE; PROTOPORPHYRINS; RATS; RATS, INBRED BN; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 0034617354     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00369-1     Document Type: Article

References (32)

1. Anderson K.E., Simionatto C.S., Drummond G.S., Kappas A. Tissue distribution and disposition of tin-protoporphyrin, a potent competitive inhibitor of heme oxygenase. J. Pharmacol. Exp. Ther. 228:1984;327-331.
2. Applegate L.A., Luscher P., Tyrrell R.M. Induction of heme oxygenase: a general response to oxidant stress in cultured mammalian cells. Cancer Res. 51:1991;974-980.
3. Camhi S.L., Alam J., Otterbein L., Sylvester S.L., Choi A.M. Induction of heme oxygenase-1 gene expression by lipopolysaccharide is mediated by AP-1 activation. Am. J. Respir. Cell Mol. Biol. 13:1995;372-387.
4. Choi A.M., Alam J. Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury. Am. J. Respir. Cell Mol. Biol. 15:1996;9-13.
5. Choi A.M., Knobil K., Otterbein S.L., Eastman D.A., Jacoby D.B. Oxidant stress responses in influenza virus pneumonia: gene expression and transcription factor activation. Am. J. Physiol. 271:1996;L383-L387.
6. Dennery P.A., Sridhar K.J., Lee C.S., Wong H.E., Shokoohi V., Rodgers P.A., Spitz D.R. Heme oxygenase-mediated resistance to oxygen toxicity in hamster fibroblasts. J. Biol. Chem. 272:1997;14937-15001.
7. Drummond G.S., Kappas A. Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidation. Proc. Natl. Acad. Sci. U. S. A. 78:1981;6466-6469.
8. Drummond G.S., Kappas A. Chemoprevention of neonatal jaundice: potency of tin-protoporphyrin in an animal model. Science. 217:1982;1250.
9. Ewing J.F., Maines M.D. Glutathione depletion induces heme oxygenase-1 (HSP32) mRNA and protein in rat brain. J. Neurochem. 60:1993;1512-1517.
10. Haddad E.-B., Liu S., Salmon M., Koto H., Barnes P.J., Chung K.F. Expression of inducible nitric oxide synthase mRNA in Brown-Norway rats exposed to ozone: effect of dexamethasone. Eur. J. Environ. Toxicol. Pharmacol. 293:1995;287-290.
11. Haddad E.B., Salmon M., Sun J., Liu S., Das A., Adcock I., Barnes P.J., Chung K.F. Dexamethasone inhibits ozone-induced gene expression of macrophage inflammatory protein-2 in rat lung. FEBS Lett. 363:1995b;285-289.
12. Haddad E.-B., Salmon M., Koto H., Barnes P.J., Adcock I., Chung K.F. Ozone induction of cytokine-induced neutrophil chemoattractant (CINC) and nuclear factor-kB in rat lung: inhibition by corticosteroids. FEBS Lett. 379:1996;265-268.
13. Hershko C. The fate of circulating haemoglobin. Br. J. Haematol. 29:1975;199-202.
14. Kappas A., Drummond G.S. Control of heme metabolism with synthetic metalloporphyrins. J. Clin. Invest. 77:1986;335-339.
15. Kappas A., Drummond G.S., Simionatto C.S., Anderson K.E. Control of heme oxygenase and plasma levels of bilirubin by a synthetic heme analogue, tin-protoporphyrin. Hepatology. 4:1984;336-341.
16. Keyse S.M., Tyrrell R.M. Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. Proc. Natl. Acad. Sci. U. S. A. 86:1989;99-102.
17. Keyse S.M., Applegate L.A., Tromvoukis Y., Tyrrell R.M. Oxidant stress leads to transcriptional activation of the human heme oxygenase gene in cultured skin fibroblasts. Mol. Cell. Biol. 10:1990;4967-4970.
18. Koto H., Salmon M., Haddad el B., Huang T.J., Zagorski J., Chung K.F. Role of cytokine-induced neutrophil chemoattractant (CINC) in ozone-induced airway inflammation and hyperresponsiveness. Am. J. Respir. Crit. Care Med. 156:1997;234-242.
19. Lautier D., Luscher P., Tyrrell R.M. Endogenous glutathione levels modulate both constitutive and UVA radiation/hydrogen peroxide inducible expression of the human heme oxygenase gene. Carcinogenesis. 13:1992;227-232.
20. Lee P.J., Alam J., Sylvester S.L., Inamdar N., Otterbein L., Choi A.M. Regulation of heme oxygenase-1 expression in vivo and in vitro in hyperoxic lung injury. Am. J. Respir. Cell Mol. Biol. 14:1996;556-560.
21. Maines M.D. Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J. 2:1988;2557-2563.
22. Maines M.D., Trakshel G.M. Differential regulation of heme oxygenase isozymes by Sn- and Zn-protoporphyrins: possible relevance to suppression of hyperbilirubinemia. Biochim. Biophys. Acta. 1131:1992;166-172.
23. Neergard K.V., Wirz K. Die messung der stromuns-winderstande in den Atemwegen des menschen, inbe sondere bei asthma und emphysema. Z. Klin. Med. 105:1927;51-60.
24. Otterbein L., Sylvester S.L., Choi A.M. Hemoglobin provides protection against lethal endotoxemia in rats: the role of heme oxygenase-1. Am. J. Respir. Cell Mol. Biol. 13:1995;595-601.
25. Otterbein L.E., Mantell L.L., Choi A.M. Carbon monoxide provides protection against hyperoxic lung injury. Am. J. Physiol. 276:1999;L-688-L-695.
26. Pendino K.J., Shuler R.L., Laskin J.D., Laskin D.L. Enhanced production of linterleukin-1, tumor necrosis factor-α, and fibronectin by rat lung phagocytes following inhalation of a pulmonary irritant. Am. J. Respir. Cell Mol. Biol. 11:1994;279-283.
27. Pimstone N.R., Engel P., Tenhunen R., Seitz P.T., Marver H.S., Schmid R. Inducible heme oxygenase in the kidney: a model for the homeostatic control of hemoglobin catabolism. J. Clin. Invest. 50:1971;2042-2047.
28. Punjabi C.J., Laskin J.D., Pendino K.J., Goller N.L., Durham S.K., Laskin D.L. Production of nitric oxide by rat type II pneumocytes: increased expression of inducible nitric oxide synthase following inhalation of a pulmonary irritant. Am. J. Respir. Cell Mol. Biol. 11:1994;165-170.
29. Salmon M., Koto H., Lynch O.T., Haddad E.B., Lamb N.J., Quinlan G.J., Barnes P.J., Chung K.F. Proliferation of airway epithelium after ozone exposure: effect of apocynin and dexamethasone. Am. J. Respir. Crit. Care Med. 157:1998;970-977.
30. Taylor J.L., Carraway M.S., Piantadosi C.A. Lung-specific induction of heme oxygenase-1 and hyperoxic lung injury. Am. J. Physiol. 274:1998;L582-L590.
31. Tsukagoshi H., Haddad A.-B., Sun J., Barnes P.J., Chung K.F. Ozone-induced airway hyperresponsiveness: role of superoxide anions, neutral endopeptidase and bradykinin receptors. J. Appl. Physiol. 78:1995;1015-1020.
32. Yoshinaga T., Sassa S., Kappas A. Purification and properties of bovine spleen heme oxygenase. Amino acid composition and sites of action of inhibitors of heme oxidation. J. Biol. Chem. 257:1982;7778-7785.