Indoxyl sulfate, a uremic toxin, promotes cell senescence in aorta of hypertensive rats

Biochemical and Biophysical Research Communications

Volumn 399, Issue 4, 2010, Pages 637-641

  Adijiang, Ayinuer ^a   Higuchi, Yusuke ^b   Nishijima, Fuyuhiko ^b   Shimizu, Hidehisa ^a   Niwa, Toshimitsu ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KUREHA CORPORATION   (Japan)

Author keywords

Aorta; Cell senescence; Hypertension; Indoxyl sulfate; Uremic toxin

Indexed keywords

ALKALINE PHOSPHATASE; BETA GALACTOSIDASE; CORE BINDING FACTOR; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; INDICAN; OSTEOCALCIN; OSTEOPONTIN; PROTEIN P53; RETINOBLASTOMA PROTEIN; CDKN1A PROTEIN, RAT; CYCLIN DEPENDENT KINASE INHIBITOR 1A;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTERIAL WALL THICKNESS; ARTERY CALCIFICATION; ARTICLE; CELL AGING; CONTROLLED STUDY; DAHL SALT SENSITIVE RAT; HYPERTENSION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SYSTOLIC BLOOD PRESSURE; ANIMAL; AORTA DISEASE; CALCINOSIS; CHEMICALLY INDUCED; DAHL RAT; DRUG EFFECTS; METABOLISM; PATHOLOGY; TOXICITY; UREMIA;

ANIMALS; AORTA; AORTIC DISEASES; BETA-GALACTOSIDASE; CALCINOSIS; CELL AGING; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; HYPERTENSION; INDICAN; RATS; RATS, INBRED DAHL; RETINOBLASTOMA PROTEIN; TUMOR SUPPRESSOR PROTEIN P53; UREMIA;

RATTUS;

EID: 77956266118     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.07.130     Document Type: Article

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