Are osteoclasts needed for the bone anabolic response to parathyroid hormone?: A study of intermittent parathyroid hormone with denosumab or alendronate in knock-in mice expressing humanized RANKL

Journal of Biological Chemistry

Volumn 285, Issue 36, 2010, Pages 28164-28173

  Pierroz, Dominique D ^a   Bonnet, Nicolas ^a   Baldock, Paul A ^b   Ominsky, Michael S ^c   Stolina, Marina ^c   Kostenuik, Paul J ^c   Ferrari, Serge L ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b ST VINCENT S HOSPITAL   (Australia)

^c AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METABOLISM;

ADDITIVE EFFECTS; ALENDRONATE; ALN; ANABOLIC RESPONSE; BONE FORMATION; BONE FORMATION RATES; BONE MASS; BONE SURFACE; BONE TURNOVER; CANCELLOUS BONE; COUPLING FACTOR; HIGH DOSE; MICRO ARCHITECTURES; OSTEOBLASTIC CELLS; OSTEOCALCIN; PARATHYROID HORMONES;

BONE;

ALENDRONIC ACID; DENOSUMAB; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; PARATHYROID HORMONE[1-34]; BIOLOGICAL MARKER; MONOCLONAL ANTIBODY; PARATHYROID HORMONE; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MASS; BONE STRENGTH; BONE STRUCTURE; BONE TURNOVER; CANCELLOUS BONE; CELL COUNT; CELL FUNCTION; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HORMONE RESPONSE; MALE; MOUSE; NONHUMAN; OSSIFICATION; OSTEOCLAST; OSTEOLYSIS; OVARIECTOMY; PRIORITY JOURNAL; WILD TYPE; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE; BONE DENSITY; BONE DEVELOPMENT; CYTOLOGY; DEFICIENCY; DOSE RESPONSE; DRUG EFFECTS; DRUG THERAPY; GENE EXPRESSION; GENE TARGETING; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY;

MUS;

ALENDRONATE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, MONOCLONAL, HUMANIZED; BIOLOGICAL MARKERS; BONE AND BONES; BONE DENSITY; BONE RESORPTION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION; GENE KNOCK-IN TECHNIQUES; HUMANS; MALE; MICE; OSTEOCLASTS; OSTEOGENESIS; OVARIECTOMY; PARATHYROID HORMONE; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B;

EID: 77956246270     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.101964     Document Type: Article

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