-
1
-
-
42049110350
-
OPG and RANKL regulation of bone remodeling in health and disease
-
Kearns AE, Khosla S, Kostenuik PJ 2008 OPG and RANKL regulation of bone remodeling in health and disease. Endocr Rev 29:155-192.
-
(2008)
Endocr Rev
, vol.29
, pp. 155-192
-
-
Kearns, A.E.1
Khosla, S.2
Kostenuik, P.J.3
-
2
-
-
0033568341
-
RANK is essential for osteoclast and lymph node development
-
DOI 10.1101/gad.13.18.2412
-
Dougall WC, Glaccum M, Charrier K, Rohrbach K, Brasel K, De Smedt T, Daro E, Smith J, Tometsko ME, Malisczewski CR, Armstrong A, Shen V, Bain S, Cosman D, Anderson D, Morrissey PJ, Peschon JJ, Schuh J 1999 RANK is essential for osteoclast and lymph node development. Genes Dev 13:2412-2424. (Pubitemid 29453612)
-
(1999)
Genes and Development
, vol.13
, Issue.18
, pp. 2412-2424
-
-
Dougall, W.C.1
Glaccum, M.2
Charrier, K.3
Rohrbach, K.4
Brasel, K.5
De Smedt, T.6
Daro, E.7
Smith, J.8
Tometsko, M.E.9
Maliszewski, C.R.10
Armstrong, A.11
Shen, V.12
Bain, S.13
Cosman, D.14
Anderson, D.15
Morrissey, P.J.16
Peschon, J.J.17
Schuh, J.18
-
3
-
-
12944262423
-
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism
-
DOI 10.1073/pnas.97.4.1566
-
Li J, Sarosi I, Yan XQ, Morony S, Capparelli C, Tan HL, McCabe S, Elliot R, Scully S, Van G, Kaufman S, Juan SC, Sun Y, Tarpley J, Martin L, Christensen K, McCabe J, Kostenuik PJ, Hsu H, Fletcher F, Dunstan CR, Lacey DL, Boyle WJ 2000 RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis, and regulation of bone mass and calcium metabolism. Proc Natl Acad Sci USA 97:1566-1571. (Pubitemid 30118482)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.4
, pp. 1566-1571
-
-
Li, J.1
Sarosi, I.2
Yan, X.-Q.3
Morony, S.4
Capparelli, C.5
Tan, H.-L.6
McCabe, S.7
Elliott, R.8
Scully, S.9
Van, G.10
Kaufman, S.11
Juan, S.-C.12
Sun, Y.13
Tarpley, J.14
Martin, L.15
Christensen, K.16
McCabe, J.17
Kostenuik, P.18
Hsu, H.19
Fletcher, F.20
Dunstan, C.R.21
Lacey, D.L.22
Boyle, W.J.23
more..
-
4
-
-
0033611467
-
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph node organogenesis
-
Kong YY, Yoshida H, Sarosi I, Tan HL, Timms E, Capparelli C, Morony S, Oliveira-dos-Santos AJ, Van G, Itie A, Khoo W, Wakeham A, Dunstan C, Lacey DL, Mak TW, Boyle WJ, Penninger JM 1999 OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph node organogenesis. Nature 397:315-323.
-
(1999)
Nature
, vol.397
, pp. 315-323
-
-
Kong, Y.Y.1
Yoshida, H.2
Sarosi, I.3
Tan, H.L.4
Timms, E.5
Capparelli, C.6
Morony, S.7
Oliveira-dos-Santos, A.J.8
Van, G.9
Itie, A.10
Khoo, W.11
Wakeham, A.12
Dunstan, C.13
Lacey, D.L.14
Mak, T.W.15
Boyle, W.J.16
Penninger, J.M.17
-
5
-
-
0032577903
-
Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin
-
DOI 10.1006/bbrc.1998.8697
-
Mizuno A, Amizuka N, Irie K, Murakami A, Fujise N, Kanno T, Sato Y, Nakagawa N, Yasuda H, Mochizuki SI, Gomibuchi T, Yano K, Shima N, Washida N, Tsuda E, Morinaga T, Higashio K, Ozawa H 1998 Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin. Biochem Biophys Res Commun 247:610-615. (Pubitemid 28418439)
-
(1998)
Biochemical and Biophysical Research Communications
, vol.247
, Issue.3
, pp. 610-615
-
-
Mizuno, A.1
Amizuka, N.2
Irie, K.3
Murakami, A.4
Fujise, N.5
Kanno, T.6
Sato, Y.7
Nakagawa, N.8
Yasuda, H.9
Mochizuki, S.-I.10
Gomibuchi, T.11
Yano, K.12
Shima, N.13
Washida, N.14
Tsuda, E.15
Morinaga, T.16
Higashio, K.17
Ozawa, H.18
-
6
-
-
0032079445
-
Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification
-
Bucay N, Sarosi I, Dunstan C, Morony S, Tarpley J, Capparelli C, Scully S, Tan HL, Xu W, Lacey DL, Boyle WJ, Simonet WS 1998 Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev 12:1260-1268. (Pubitemid 28213402)
-
(1998)
Genes and Development
, vol.12
, Issue.9
, pp. 1260-1268
-
-
Bucay, N.1
Sarosi, I.2
Dunstan, C.R.3
Morony, S.4
Tarpley, J.5
Capparelli, C.6
Scully, S.7
Tan, H.L.8
Xu, W.9
Lacey, D.L.10
Boyle, W.J.11
Simonet, W.S.12
-
7
-
-
18444379071
-
Transgenic mice overexpressing soluble osteoclast differentiation factor (sODF) exhibit severe osteoporosis
-
DOI 10.1007/s007740200049
-
Mizuno A, Kanno T, Hoshi M, Shibata O, Yano K, Fujise N, Kinosaki M, Yamaguchi K, Tsuda E, Murakami A, Yasuda H, Higashio K 2002 Transgenic mice overexpressing soluble osteoclast differentiation factor (sODF) exhibit severe osteoporosis. J Bone Miner Metab 20:337-344. (Pubitemid 40645655)
-
(2002)
Journal of Bone and Mineral Metabolism
, vol.20
, Issue.6
, pp. 337-344
-
-
Mizuno, A.1
Kanno, T.2
Hoshi, M.3
Shibata, O.4
Yano, K.5
Fujise, N.6
Kinosaki, M.7
Yamaguchi, K.8
Tsuda, E.9
Murakami, A.10
Yasuda, H.11
Higashio, K.12
-
8
-
-
0031005576
-
Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
-
Simonet WS, Lacey DL, Dunstan C, Kelly M, Chang MS, Luthy R, Nhuyen HQ, Wooden S, Bennett L, Boone T, Shimamoto G, DeRose M, Elliot R, Colombero A, Tan HL, Trail G, Sullivan J, Davy E, Bucay N, Renshaw-Gegg L, Hughes TM, Hill D, Pattison W, Campbell P, Sander S, Van G, Tarpley J, Derby P, Lee R, Boyle WJ 1997 Osteoprotegerin: A novel secreted protein involved in the regulation of bone density. Cell 89:309-319. (Pubitemid 27199902)
-
(1997)
Cell
, vol.89
, Issue.2
, pp. 309-319
-
-
Simonet, W.S.1
Lacey, D.L.2
Dunstan, C.R.3
Kelley, M.4
Chang, M.-S.5
Luthy, R.6
Nguyen, H.Q.7
Wooden, S.8
Bennett, L.9
Boone, T.10
Shimamoto, G.11
Derose, M.12
Elliott, R.13
Colombero, A.14
Tan, H.-L.15
Trall, G.16
Sullivan, J.17
Davy, E.18
Bucay, N.19
Renshaw-Gegg, L.20
Hughes, T.M.21
Hill, D.22
Pattison, W.23
Campbell, P.24
Sander, S.25
Van, G.26
Tarpley, J.27
Derby, P.28
Lee, R.29
Boyle, W.J.30
more..
-
9
-
-
0034915025
-
The effects of osteoprotegerin on the mechanical properties of rat bone
-
DOI 10.1023/A:1011229324412
-
Ross AB, Bateman TA, Kostenuik PJ, Ferguson VL, Lacey DL, Dunstan CR, Simske SJ 2001 The effects of osteoprotegerin on the mechanical properties of rat bone. J Mater Sei Mater Med 12:583-588. (Pubitemid 32682113)
-
(2001)
Journal of Materials Science: Materials in Medicine
, vol.12
, Issue.7
, pp. 583-588
-
-
Ross, A.B.1
Bateman, T.A.2
Kostenuik, P.J.3
Ferguson, V.L.4
Lacey, D.L.5
Dunstan, C.R.6
Simske, S.J.7
-
10
-
-
0034816809
-
OPG and PTH-(1-34) have additive effects on bone density and mechanical strength in osteopenic ovariectomized rats
-
DOI 10.1210/en.142.10.4295
-
Kostenuik PJ, Capparelli C, Morony S, Adamu S, Shimamoto G, Shen V, Lacey DL, Dunstan CR 2001 OPG and PTH-(1-34) have additive effects on bone density and mechanical strength in osteopenic ovariectomized rats. Endocrinology 142:4295-4305. (Pubitemid 32907057)
-
(2001)
Endocrinology
, vol.142
, Issue.10
, pp. 4295-4304
-
-
Kostenuik, P.J.1
Capparelli, C.2
Morony, S.3
Adamu, S.4
Shimamoto, G.5
Shen, V.6
Lacey, D.L.7
Dunstan, C.R.8
-
11
-
-
33845934478
-
Co-treatment of PTH with osteoprotegerin or alendronate increases its anabolic effect on the skeleton of oophorectomized mice
-
DOI 10.1359/jbmr.060915
-
Samadfam R, Xia Q, Goltzman D 2007 Co-treatment of PTH with osteoprotegerin or alendronate increases its anabolic effect on the skeleton of oophorectomized mice. J Bone Miner Res 22:55-63. (Pubitemid 46032597)
-
(2007)
Journal of Bone and Mineral Research
, vol.22
, Issue.1
, pp. 55-63
-
-
Samadfam, R.1
Xia, Q.2
Goltzman, D.3
-
12
-
-
11244334478
-
Osteoclastogenesis inhibitory factor/osteoprotegerin reduced bone loss induced by mechanical unloading
-
DOI 10.1007/s00223-004-0028-x
-
Ichinose Y, Tanaka H, Inoue M, Mochizuki S, Tsuda E, Seino Y 2004 Osteoclastogenesis inhibitor factor/osteoprotegerin reduced bone loss induced by mechanical unloading. Calcif Tissue Int 75:338-343. (Pubitemid 40064236)
-
(2004)
Calcified Tissue International
, vol.75
, Issue.4
, pp. 338-343
-
-
Ichinose, Y.1
Tanaka, H.2
Inoue, M.3
Mochizuki, S.4
Tsuda, E.5
Seino, Y.6
-
13
-
-
27744599521
-
Review: Circulating osteoprotegerin and receptor activator for nuclear factor κB ligand: Clinical utility in metabolic bone disease assessment
-
DOI 10.1210/jc.2005-0794
-
Rogers A, Eastell R 2005 REVIEW: Circulating osteoprotegerin ligand and receptor activator for nuclear factor κB ligand: Clinical utility in metabolic bone disease assessment. J Clin Endocrinol Metab 90:6323-6331. (Pubitemid 41606564)
-
(2005)
Journal of Clinical Endocrinology and Metabolism
, vol.90
, Issue.11
, pp. 6323-6331
-
-
Rogers, A.1
Eastell, R.2
-
14
-
-
27744529640
-
Osteoprotegerin and RANKL regulate bone resorption, density, geometry and strength
-
Kostenuik PJ 2005 Osteoprotegerin and RANKL regulate bone resorption, density, geometry and strength. Curr Opin Pharmacol 5:618-625.
-
(2005)
Curr Opin Pharmacol
, vol.5
, pp. 618-625
-
-
Kostenuik, P.J.1
-
15
-
-
24644434101
-
RANKL is a marker and mediator of local and systemic bone loss in two rat models of inflammatory arthritis
-
DOI 10.1359/JBMR.050601
-
Stolina M, Adamu S, Ominsky MS, Dzamba BJ, Asuncion F, Geng Z, Middleton S, Brown H, Pretorius J, Schett G, Bolon B, Feige U, Zack D, Kostenuik PJ 2005 RANKL is a marker and mediator of local and systemic bone loss in two rat models of inflammatory arthritis. J Bone Miner Res 20:1756-1765. (Pubitemid 41361876)
-
(2005)
Journal of Bone and Mineral Research
, vol.20
, Issue.10
, pp. 1756-1765
-
-
Stolina, M.1
Adamu, S.2
Ominsky, M.3
Dwyer, D.4
Asuncion, F.5
Geng, Z.6
Middleton, S.7
Brown, H.8
Pretorius, J.9
Schett, G.10
Bolon, B.11
Feige, U.12
Zack, D.13
Kostenuik, P.J.14
-
16
-
-
0018306059
-
THRESHOLD SELECTION METHOD from GRAY-LEVEL HISTOGRAMS
-
Otsu N 1979 A threshold selection method from gray-level histograms. IEEE Trans Syst Man Cybern 9:62-66. (Pubitemid 9413341)
-
(1979)
IEEE Trans Syst Man Cybern
, vol.SMC-9
, Issue.1
, pp. 62-66
-
-
Otsu, N.1
-
17
-
-
38849169884
-
ContinuousRANKL inhibition in OPG transgenic mice and rats suppresses bone resorption without impairing lymphorganogenesis or functional immune responses
-
Stolina M, Dwyer D, Ominsky MS, Corbin T, Van G, Bolon B, Sarosi I, McCabe J, Zack D, Kostenuik PJ 2007 ContinuousRANKL inhibition in OPG transgenic mice and rats suppresses bone resorption without impairing lymphorganogenesis or functional immune responses. J Immunol 179:7497-7505.
-
(2007)
J Immunol
, vol.179
, pp. 7497-7505
-
-
Stolina, M.1
Dwyer, D.2
Ominsky, M.S.3
Corbin, T.4
Van, G.5
Bolon, B.6
Sarosi, I.7
McCabe, J.8
Zack, D.9
Kostenuik, P.J.10
-
18
-
-
23044509872
-
The inhibition of RANKL causes greater suppression of bone resorption and hypercalcemia compared with bisphosphonates in two models of humoral hypercalcemia of malignancy
-
DOI 10.1210/en.2004-1583
-
Morony S, Warmington K, Adamu S, Asuncion F, Geng Z, Grisanti M, Tan HL, Capparelli C, Starnes C, Weimann B, Dunstan CR, Kostenuik PJ 2005 The RANKL inhibitor osteoprotegerin (OPG) causes greater suppression of bone resorption and hypercalcemia compared to bisphosphonates in two models of humoral hypercalcemia of malignancy. Endocrinology 146:3235-3243. (Pubitemid 41058092)
-
(2005)
Endocrinology
, vol.146
, Issue.8
, pp. 3235-3243
-
-
Morony, S.1
Warmington, K.2
Adamu, S.3
Asuncion, F.4
Geng, Z.5
Grisanti, M.6
Hong, L.T.7
Capparelli, C.8
Starnes, C.9
Weimann, B.10
Dunstan, C.R.11
Kostenuik, P.J.12
-
19
-
-
33344469853
-
Denosumab in postmenopausal women with low bone mineral density
-
DOI 10.1056/NEJMoa044459
-
McClung MR, Lewiecki EM, Cohen SB, Bolognese MA, Woodson GC, Moffett AH, Peacock M, Miller PD, Lederman SN, Chesnut CH, Lain D, Kivitz AJ, Holloway DL, Zhang C, Peterson MC, Bekker PJ 2006 Denosumab in postmenopausal women with low bone mineral density. N Engl J Med 354: 821-831. (Pubitemid 43290920)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.8
, pp. 821-831
-
-
McClung, M.R.1
Michael Lewiecki, E.2
Cohen, S.B.3
Bolognese, M.A.4
Woodson, G.C.5
Moffett, A.H.6
Peacock, M.7
Miller, P.D.8
Lederman, S.N.9
Chesnut, C.H.10
Lain, D.11
Kivitz, A.J.12
Holloway, D.L.13
Zhang, C.14
Peterson, M.C.15
Bekker, P.J.16
-
20
-
-
58149099647
-
Comparison of the effect of denosumab and alendronate on bone mineral density and biochemical markers of bone turnover in postmenopausal women with low bone mass: A randomized, blinded, phase 3 trial
-
Brown JP, Prince RL, Deal C, Recker RR, Kiel DP, de Gregorio LH, Hadji P, Hofbauer LC, Alvaro-Gracia JM, Wang H, Austin M, Wagman RB, Newmark R, Libanati C, San Martin J, Bone HG 2009 Comparison of the effect of denosumab and alendronate on bone mineral density and biochemical markers of bone turnover in postmenopausal women with low bone mass: A randomized, blinded, phase 3 trial. J Bone Miner Res 24:153-161.
-
(2009)
J Bone Miner Res
, vol.24
, pp. 153-161
-
-
Brown, J.P.1
Prince, R.L.2
Deal, C.3
Recker, R.R.4
Kiel, D.P.5
De Gregorio, L.H.6
Hadji, P.7
Hofbauer, L.C.8
Alvaro-Gracia, J.M.9
Wang, H.10
Austin, M.11
Wagman, R.B.12
Newmark, R.13
Libanati, C.14
San Martin, J.15
Bone, H.G.16
-
21
-
-
70349112916
-
Serum OPG levels are correlated positively with bone strength and inversely with bone turnover in mature OPG transgenic rats
-
Ominsky MS, Corbin T, Stolina M, Dwyer D, Li X, Morony S, Warmington KS, Geng Z, Grisanti M, Tan H, Adamu S, Asuncion F, Bolon B, McCabe J, Kostenuik PJ 2006 Serum OPG levels are correlated positively with bone strength and inversely with bone turnover in mature OPG transgenic rats. Calcif Tissue Int 78:S34.
-
(2006)
Calcif Tissue Int
, vol.78
-
-
Ominsky, M.S.1
Corbin, T.2
Stolina, M.3
Dwyer, D.4
Li, X.5
Morony, S.6
Warmington, K.S.7
Geng, Z.8
Grisanti, M.9
Tan, H.10
Adamu, S.11
Asuncion, F.12
Bolon, B.13
McCabe, J.14
Kostenuik, P.J.15
-
22
-
-
0036284616
-
Changes in bone density and turnover explain the reductions in incidence of nonvertebral fractures that occur during treatment with antiresorptive agents
-
DOI 10.1210/jc.87.4.1586
-
Hochberg MC, Greenspan S, Wasnich RD, Miller P, Thompson DE, Ross PD 2002 Changes in bone density and turnover explain the reduction in incidence of nonvertebral fractures that occur during treatment with antiresorptive agents. J Clin Endocrinol Metab 87:1586-1592. (Pubitemid 34615244)
-
(2002)
Journal of Clinical Endocrinology and Metabolism
, vol.87
, Issue.4
, pp. 1586-1592
-
-
Hochberg, M.C.1
Greenspan, S.2
Wasnich, R.D.3
Miller, P.4
Thompson, D.E.5
Ross, P.D.6
-
23
-
-
0036020416
-
Age and distance from the surface but not menopause reduce osteocyte density in human cancellous bone
-
DOI 10.1016/S8756-3282(02)00819-0, PII S8756328202008190
-
Qiu S, Rao DS, Palnitkar S, Parfitt AM 2002 Age and distance from the surface but not menopause reduce osteocyte density in human cancellous bone. Bone 31:313-318. (Pubitemid 34822826)
-
(2002)
Bone
, vol.31
, Issue.2
, pp. 313-318
-
-
Qiu, S.1
Rao, D.S.2
Palnitkar, S.3
Parfitt, A.M.4
-
24
-
-
0000345316
-
In vivo osteocyte death
-
Frost HM 1960 In vivo osteocyte death. J Bone Joint Surg Am 42:138-143.
-
(1960)
J Bone Joint Surg Am
, vol.42
, pp. 138-143
-
-
Frost, H.M.1
-
25
-
-
41649087740
-
Quantitative associations between osteocyte density and biomechanics, microcrack and microstructure in OVX rats vertebral trabeculae
-
Ma Y-L, Dai RC, Sheng ZF, Jin Y, Zhang YH, Fang LN, Fan HJ, Liao EY 2008 Quantitative associations between osteocyte density and biomechanics, microcrack and microstructure in OVX rats vertebral trabeculae. J Biomech 41:1324-1332.
-
(2008)
J Biomech
, vol.41
, pp. 1324-1332
-
-
Ma, Y.-L.1
Dai, R.C.2
Sheng, Z.F.3
Jin, Y.4
Zhang, Y.H.5
Fang, L.N.6
Fan, H.J.7
Liao, E.Y.8
-
26
-
-
42449146580
-
RANKL inhibition with osteoprotegerin increases bone strength by improving cortical and trabecular bone architecture in ovariectomized rats
-
DOI 10.1359/jbmr.080109
-
Ominsky MS, Li X, Asuncion F, Barrero M, Warmington K, Dwyer D, Stolina M, Geng Z, Grisanti M, Tan HL, Corbin T, McCabe J, Simonet WS, Ke HZ, Kostenuik PJ 2008 RANKL inhibition with osteoprotegerin (OPG) increases bone strength by improving cortical and trabecular bone achitecture in ovariectomized rats. J Bone Miner Res 23:672-682. (Pubitemid 351575021)
-
(2008)
Journal of Bone and Mineral Research
, vol.23
, Issue.5
, pp. 672-682
-
-
Ominsky, M.S.1
Li, X.2
Asuncion, F.J.3
Barrero, M.4
Warmington, K.S.5
Dwyer, D.6
Stolina, M.7
Geng, Z.8
Grisanti, M.9
Tan, H.-L.10
Corbin, T.11
McCabe, J.12
Simonet, W.S.13
Ke, H.Z.14
Kostenuik, P.J.15
-
27
-
-
0142187130
-
Serum levels of osteoprotegerin increase with age in a healthy adult population
-
DOI 10.1016/S8756-3282(03)00090-5
-
Kudlacek S, Schneider B, Woloszczuk W, Pietschmann P, Willvonseder R 2003 Serum levels of osteoprotegerin increase with age in a healthy adult population. Bone 32:681-686. (Pubitemid 37303940)
-
(2003)
Bone
, vol.32
, Issue.6
, pp. 681-686
-
-
Kudlacek, S.1
Schneider, B.2
Woloszczuk, W.3
Pietschmann, P.4
Willvonseder, R.5
-
28
-
-
41849123884
-
Differential bone metabolism between postmenopausal women with osteoarthritis and osteoporosis
-
Jiang LS, Zhang ZM, Jiang SD, Chen WH, Dai LY 2008 Differential bone metabolism between postmenopausal women with osteoarthritis and osteoporosis. J Bone Miner Res 23:475-483.
-
(2008)
J Bone Miner Res
, vol.23
, pp. 475-483
-
-
Jiang, L.S.1
Zhang, Z.M.2
Jiang, S.D.3
Chen, W.H.4
Dai, L.Y.5
-
29
-
-
18044394042
-
Circulating amounts of osteoprotegerin and RANK ligand: Genetic influence and relationship with BMD assessed in female twins
-
DOI 10.1016/j.bone.2004.12.015
-
Abrahamsen B, Hjelmborg J, Kostenuik PJ, Stilgren LS, Kyvik K, Adamu S, Brixen K, Langdahl BL 2005 Circulating amounts of osteoprotegerin and RANK ligand: Genetic influence and relationship with BMD assessed in female twins. Bone 36:727-735. (Pubitemid 40602267)
-
(2005)
Bone
, vol.36
, Issue.4
, pp. 727-735
-
-
Abrahamsen, B.1
Hjelmborg, J.V.2
Kostenuik, P.3
Stilgren, L.S.4
Kyvik, K.5
Adamu, S.6
Brixen, K.7
Langdahl, B.L.8
-
30
-
-
33751536723
-
No associations between OPG gene polymorphisms or serum levels and measures of osteoporosis in elderly Australian women
-
DOI 10.1016/j.bone.2006.06.022, PII S8756328206005813
-
Ueland T, Bollerslev J, Wilson SG, Dick IM, Islam F, Mullin BH, Devine A, Prince RL 2007 No associations between OPG gene polymorphisms or serum levels and measures of osteoporosis in elderly Australian women. Bone 40:175-181. (Pubitemid 44839322)
-
(2007)
Bone
, vol.40
, Issue.1
, pp. 175-181
-
-
Ueland, T.1
Bollerslev, J.2
Wilson, S.G.3
Dick, I.M.4
Islam, F.M.A.5
Mullin, B.H.6
Devine, A.7
Prince, R.L.8
-
31
-
-
0142122879
-
Sustained Antiresorptive Effects after a Single Treatment with Human Recombinant Osteoprotegerin (OPG): A Pharmacodynamic and Pharmacokinetic Analysis in Rats
-
DOI 10.1359/jbmr.2003.18.5.852
-
Capparelli C, Morony S, Warmington K, Adamu S, Lacey D, Dunstan CR, Stouch B, Martin S, Kostenuik PJ 2003 Sustained antiresorptive effects after a single treatment with human recombinant osteoprotegerin (OPG): A pharmacodynamic and pharmacokinetic analysis in rats. J Bone Miner Res 18:852-858. (Pubitemid 37294968)
-
(2003)
Journal of Bone and Mineral Research
, vol.18
, Issue.5
, pp. 852-858
-
-
Capparelli, C.1
Morony, S.2
Warmington, K.3
Adamu, S.4
Lacey, D.5
Dunstan, C.R.6
Stouch, B.7
Martin, S.8
Kostenuik, P.J.9
-
32
-
-
0033555651
-
Osteoprotegerin and osteoprotegerin ligand effects on osteoclast formation from human peripheral blood mononuclear cell precursors
-
DOI 10.1002/(SICI)1097-4644(19990201)72:2<251::AID-JCB9>3.0.CO;2-W
-
Shalhoub V, Faust J, Boyle WJ, Dunstan C, Kelley MJ, Kaufman S, Scully S, van Auken M, Lacey DL 1999 Osteoprotegerin and osteoprotegerin ligand effects on osteoclast formation from human peripheral blood mononuclear cell precursors. J Cell Biochem 72:251-261. (Pubitemid 29021938)
-
(1999)
Journal of Cellular Biochemistry
, vol.72
, Issue.2
, pp. 251-261
-
-
Shalhoub, V.1
Faust, J.2
Boyle, W.J.3
Dunstan, C.R.4
Kelley, M.5
Kaufman, S.6
Scully, S.7
Van, G.8
Lacey, D.L.9
-
33
-
-
37049239211
-
Osteopetrosis cured by temporary parabiosis
-
Walker DG 1973 Osteopetrosis cured by temporary parabiosis. Science 180:875.
-
(1973)
Science
, vol.180
, pp. 875
-
-
Walker, D.G.1
-
34
-
-
0034913371
-
Expression profiles of receptor activator of nuclear factor κB ligand, receptor activator of nuclear factor κB, and osteoprotegerin messenger RNA in aged and ovariectomized rat bones
-
Ikeda T, Utsuyama M, Hirokawa K 2001 Expression profiles of receptor activator of nuclear factor κB ligand, receptor activator of nuclear factor KB, and osteoprotegerin messenger mRAN in aged ovariectomized rat bones. J Bone Miner Res 16:1416-1425. (Pubitemid 32675193)
-
(2001)
Journal of Bone and Mineral Research
, vol.16
, Issue.8
, pp. 1416-1425
-
-
Ikeda, T.1
Utsuyama, M.2
Hirokawa, K.3
-
35
-
-
17744388339
-
Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function
-
DOI 10.1210/en.141.9.3478
-
Udagawa N, Takahashi N, Yasuda H, Mizuno A, Itoh K, Ueno Y, Shinki T, Gillespie MT, Martin TJ, Higashio K, Suda T 2000 Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function. Endocrinology 141:3478-3484. (Pubitemid 32269038)
-
(2000)
Endocrinology
, vol.141
, Issue.9
, pp. 3478-3484
-
-
Udagawa, N.1
Takahashi, N.2
Yasuda, H.3
Mizuno, A.4
Itoh, K.5
Ueno, Y.6
Shinki, T.7
Gillespie, M.T.8
Martin, T.J.9
Higashio, K.10
Suda, T.11
-
36
-
-
0036069455
-
Localization of osteoprotegerin (OPG) on bone surfaces and cement lines in rat tibia
-
Nakamura H, Tsuji T, Hirata A, Yamamoto T 2002 Localization of osteoprotegerin (OPG) on bone surfaces and cement lines in rat tibia. J Histochem Cytochem 50:945-953. (Pubitemid 34774605)
-
(2002)
Journal of Histochemistry and Cytochemistry
, vol.50
, Issue.7
, pp. 945-953
-
-
Nakamura, H.1
Tsuji, T.2
Hirata, A.3
Yamamoto, T.4
-
37
-
-
34250008136
-
Dried plum prevents bone loss in a male osteoporosis model via IGF-I and the RANK pathway
-
DOI 10.1016/j.bone.2006.05.024, PII S8756328206005527
-
Franklin M, Bu SY, Lerner MR, Lancaster EA, Bellmer D, Marlow D, Lightfoot SA, Arjmandi BH, Brackett DJ, Lucas EA, Smith BJ 2006 Dried plum prevents bone loss in a male osteoporosis model via IGF-I and the RANK pathway. Bone 39:1331-1342. (Pubitemid 44827913)
-
(2006)
Bone
, vol.39
, Issue.6
, pp. 1331-1342
-
-
Franklin, M.1
Bu, S.Y.2
Lerner, M.R.3
Lancaster, E.A.4
Bellmer, D.5
Marlow, D.6
Lightfoot, S.A.7
Arjmandi, B.H.8
Brackett, D.J.9
Lucas, E.A.10
Smith, B.J.11
-
38
-
-
41049097330
-
OPG and RANKL mRNA and protein expressions in the primary and secondary metaphyseal trabecular bone of PTH-treated rats are independent of that of SOST
-
Silvestrini G, Ballanti P, Sebastiani M, Leopizzi M, Di Vito M, Bonucci E 2008 OPG and RANKL mRNA and protein expressions in the primary and secondary metaphyseal trabecular bone of PTH-treated rats are independent of that of SOST. J Mol Histol 39:237-242.
-
(2008)
J Mol Histol
, vol.39
, pp. 237-242
-
-
Silvestrini, G.1
Ballanti, P.2
Sebastiani, M.3
Leopizzi, M.4
Di Vito, M.5
Bonucci, E.6
-
39
-
-
34547481944
-
RANKL inhibition via osteoprotegerin blocks bone loss in experimental periodontitis
-
Jin Q, Cirelli JA, Park CH, Sugai JV, Taba M, Kostenuik PJ, Giannobile WV 2007 RANKL inhibition via osteoprotegerin blocks bone loss in experimental periodontitis. J Periodontol 78:1300-1308.
-
(2007)
J Periodontol
, vol.78
, pp. 1300-1308
-
-
Jin, Q.1
Cirelli, J.A.2
Park, C.H.3
Sugai, J.V.4
Taba, M.5
Kostenuik, P.J.6
Giannobile, W.V.7
-
40
-
-
33845206554
-
RANKL inhibition: A novel strategy to decrease femoral head deformity after ischemic osteonecrosis
-
DOI 10.1359/jbmr.060905
-
Kim H, Morgan-Bagley S, Kostenuik PJ 2006 RANKL inhibition: A novel strategy to decrease femoral head deformity after ischemic necrosis. J Bone Miner Res 21:1946-1954. (Pubitemid 44851571)
-
(2006)
Journal of Bone and Mineral Research
, vol.21
, Issue.12
, pp. 1946-1954
-
-
Kim, H.K.W.1
Morgan-Bagley, S.2
Kostenuik, P.3
-
41
-
-
0032540137
-
Characterization of monomeric and homodimeric forms of osteoclastogenesis inhibitory factor
-
DOI 10.1006/bbrc.1998.8443
-
Tomoyasu A, Goto M, Fujise N, Mochizuki SI, Yasuda H, Morinaga T, Tsuda E, Higashio K 1998 Characterization of monomeric and homodimeric forms of osteoclastogenesis inhibitory factor. Biochem Biophys Res Commun 245:382-387. (Pubitemid 28418509)
-
(1998)
Biochemical and Biophysical Research Communications
, vol.245
, Issue.2
, pp. 382-387
-
-
Tomoyasu, A.1
Goto, M.2
Fujise, N.3
Mochizuki, S.-I.4
Yasuda, H.5
Morinaga, T.6
Tsuda, E.7
Higashio, K.8
-
42
-
-
61849154722
-
The evolving systemic and local biomarker milieu at different stages of disease progression in rat adjuvant-induced arthritis
-
in press
-
Stolina M, Bolon B, Middleton S, Dwyer D, Brown H, Duryea D, Zhu L, Rohner A, Pretorius J, Kostenuik PJ, Feige U, Zack D 2008 The evolving systemic and local biomarker milieu at different stages of disease progression in rat adjuvant-induced arthritis. J Clin Immunol (in press).
-
(2008)
J Clin Immunol
-
-
Stolina, M.1
Bolon, B.2
Middleton, S.3
Dwyer, D.4
Brown, H.5
Duryea, D.6
Zhu, L.7
Rohner, A.8
Pretorius, J.9
Kostenuik, P.J.10
Feige, U.11
Zack, D.12
-
43
-
-
0027508198
-
Interrelationships between densitometric, geometric, and mechanical properties of rat femora: Inferences concerning mechanical regulation of bone modeling
-
Ferretti JL, Capozza RF, Mondelo N, Zanchetta JR 1993 Interrelationships between densitometric, geometric and mechanical properties of rat femora: Inferences concerning mechanical regulation of bone modeling. J Bone Miner Res 8:1389-1396. (Pubitemid 23321701)
-
(1993)
Journal of Bone and Mineral Research
, vol.8
, Issue.11
, pp. 1389-1396
-
-
Ferretti, J.L.1
Capozza, R.F.2
Mondelo, N.3
Zanchetta, J.R.4
-
44
-
-
0023492075
-
Bone "mass" and the "mechanostat": A proposal
-
Frost HM 1987 Bone "mass" and the "mechanostat": A proposal. Anat Rec 219:1-9.
-
(1987)
Anat Rec
, vol.219
, pp. 1-9
-
-
Frost, H.M.1
-
45
-
-
34249930052
-
Sclerosing bone disorders
-
Favus MJ (ed.) American Society for Bone and Mineral Research, Washington, DC, USA
-
Whyte MP 2006 Sclerosing bone disorders. In: Favus MJ (ed.) Primer on the Metabolic Bone Disease and Disorders of Mineral Metabolism, 6th ed. American Society for Bone and Mineral Research, Washington, DC, USA, pp. 398-414.
-
(2006)
Primer on the Metabolic Bone Disease and Disorders of Mineral Metabolism, 6th Ed.
, pp. 398-414
-
-
Whyte, M.P.1
-
46
-
-
20444394771
-
Quantification of metaphyseal modeling in children treated with bisphosphonates
-
DOI 10.1016/j.bone.2005.02.016, PII S8756328205000645
-
Ward K, Cowell CT, Little DG 2005 Quantification of metaphyseal modeling in children treated with bisphosphonates. Bone 36:999-1002. (Pubitemid 40798000)
-
(2005)
Bone
, vol.36
, Issue.6
, pp. 999-1002
-
-
Ward, K.1
Cowell, C.T.2
Little, D.G.3
-
47
-
-
0036139938
-
Mechanical properties in long bones of rat osteopetrotic mutations
-
DOI 10.1016/S0021-9290(01)00203-2, PII S0021929001002032
-
Jamsa T, Rho JY, Fan Z, Mackay CA, Marks SC, Tuukkanen J 2002 Mechanical properties in long bones of rat osteopetrotic mutations. J Biomech 35:161-165. (Pubitemid 34037091)
-
(2002)
Journal of Biomechanics
, vol.35
, Issue.2
, pp. 161-165
-
-
Jamsa, T.1
Rho, J.-Y.2
Fan, Z.3
MacKay, C.A.4
Marks Jr., S.C.5
Tuukkanen, J.6
-
48
-
-
0033819342
-
Mineral density and bone strength are dissociated in long bones of rat osteopetrotic mutations
-
Tuukkanen J, Koivukangas A, Jamsa T, Sundquist K, Mackay CA, Marks SC 2000 Mineral density and bone strength are dissociated in long bones of rat osteopetrotic mutations. J Bone Miner Res 25:1905-1911. (Pubitemid 30760632)
-
(2000)
Journal of Bone and Mineral Research
, vol.15
, Issue.10
, pp. 1905-1911
-
-
Tuukkanen, J.1
Koivukangas, A.2
Jamsa, T.3
Sundquist, K.4
Mackay, C.A.5
Marks Jr., S.C.6
-
49
-
-
17644376504
-
Intravenous neridronate in children with osteogenesis imperfecta: A randomized controlled study
-
DOI 10.1359/JBMR.041232
-
Gatti D, Antoniazzi F, Prizzi R, Braga V, Rossini M, Tato L, Viapiana O, Adami S 2005 Intravenous neridronate in children with osteogenesis imperfecta: A randomized controlled study. J Bone Miner Res 20:758-763. (Pubitemid 40571632)
-
(2005)
Journal of Bone and Mineral Research
, vol.20
, Issue.5
, pp. 758-763
-
-
Gatti, D.1
Antoniazzi, F.2
Prizzi, R.3
Braga, V.4
Rossini, M.5
Tato, L.6
Viapiana, O.7
Adami, S.8
-
50
-
-
33646502801
-
Should children with osteogenesis imperfecta be treated with bisphosphonates?
-
Marini JC 2006 Should children with osteogenesis imperfecta be treated with bisphosphonates?. Nat Clin Pract Endocrinol Metab 2:14-15.
-
(2006)
Nat Clin Pract Endocrinol Metab
, vol.2
, pp. 14-15
-
-
Marini, J.C.1
-
51
-
-
0041842634
-
Bisphosphonate-induced osteopetrosis
-
Whyte MP, Wenkert D, Clements KL, McAlister WH, Mumm S 2003 Bisphosphonate-induced osteopetrosis. N Engl J Med 349:457-463.
-
(2003)
N Engl J Med
, vol.349
, pp. 457-463
-
-
Whyte, M.P.1
Wenkert, D.2
Clements, K.L.3
McAlister, W.H.4
Mumm, S.5
-
52
-
-
0034083360
-
Osteoprotegerin mitigates tail suspension-induced osteopenia
-
Bateman TA, Dunstan CR, Ferguson VL, Lacey DL, Ayers RA, Simske SJ 2000 Osteoprotegerin mitigates tail suspension-induced osteopenia. Bone 26:443-449.
-
(2000)
Bone
, vol.26
, pp. 443-449
-
-
Bateman, T.A.1
Dunstan, C.R.2
Ferguson, V.L.3
Lacey, D.L.4
Ayers, R.A.5
Simske, S.J.6
-
53
-
-
34347394402
-
The RANKL inhibitor OPG-Fc increases cortical and trabecular bone mass in young gonad-intact cynomolgus monkeys
-
DOI 10.1007/s00198-007-0363-7
-
Ominsky MS, Kostenuik PJ, Cranmer P, Smith SY, Atkinson JE 2007 The RANKL inhibitor OPG-Fc increases cortical and trabecular bone mass in intact cynomolgus monkeys. Osteoporos Int 18:1073-1082. (Pubitemid 47020009)
-
(2007)
Osteoporosis International
, vol.18
, Issue.8
, pp. 1073-1082
-
-
Ominsky, M.S.1
Kostenuik, P.J.2
Cranmer, P.3
Smith, S.Y.4
Atkinson, J.E.5
-
54
-
-
0027279616
-
Continuous alendronate treatment throughout growth, maturation, and aging in the rat results in increases in bone mass and mechanical properties
-
Guy JA, Shea M, Peter CP, Morrissey R, Hayes WC 1993 Continuous alendronate treatment throughout growth, maturation, and aging in the rat results in increases in bone mass and mechanical properties. Calcif Tissue Int 53:283-288. (Pubitemid 23275192)
-
(1993)
Calcified Tissue International
, vol.53
, Issue.4
, pp. 283-288
-
-
Guy, J.A.1
Shea, M.2
Peter, C.P.3
Morrissey, R.4
Hayes, W.C.5
|