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Volumn 148, Issue 9, 2007, Pages 4466-4474

The effects of combination of alendronate and human parathyroid hormone(1-34) on bone strength are synergistic in the lumbar vertebra and additive in the femur of C57BL/6J mice

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; PARATHYROID HORMONE[1-34];

EID: 34548089429     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2007-0229     Document Type: Article
Times cited : (26)

References (46)
  • 1
    • 0030804947 scopus 로고    scopus 로고
    • Randomised controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosis
    • Lindsay R, Nieves J, Formica C, Henneman E, Woelfert L, Shen V, Dempster D, Cosman F 1997 Randomised controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosis. Lancet 350:550-555
    • (1997) Lancet , vol.350 , pp. 550-555
    • Lindsay, R.1    Nieves, J.2    Formica, C.3    Henneman, E.4    Woelfert, L.5    Shen, V.6    Dempster, D.7    Cosman, F.8
  • 3
    • 33846332080 scopus 로고    scopus 로고
    • New mechanisms and targets in the treatment of bone fragility
    • Martin TJ, Seeman E 2007 New mechanisms and targets in the treatment of bone fragility. Clin Sci (Lond) 112:77-91
    • (2007) Clin Sci (Lond) , vol.112 , pp. 77-91
    • Martin, T.J.1    Seeman, E.2
  • 4
    • 0242503684 scopus 로고    scopus 로고
    • New insights into the molecular mechanisms of actions of bisphosphonates
    • Rogers MJ 2003 New insights into the molecular mechanisms of actions of bisphosphonates. Curr Pharm Des 9:2643-2658
    • (2003) Curr Pharm Des , vol.9 , pp. 2643-2658
    • Rogers, M.J.1
  • 6
    • 33646565019 scopus 로고    scopus 로고
    • Drug insights: Bisphosphonates for postmenopausal osteoporosis
    • Chapurlat RD, Delmas PD 2006 Drug insights: bisphosphonates for postmenopausal osteoporosis. Nat Clin Pract Endocrinol Metab 2:211-219
    • (2006) Nat Clin Pract Endocrinol Metab , vol.2 , pp. 211-219
    • Chapurlat, R.D.1    Delmas, P.D.2
  • 7
    • 0034520352 scopus 로고    scopus 로고
    • In vivo effects of bisphosphonates on the osteoclast mevalonate pathway
    • Fisher JE, Rodan GA, Reszka AA 2000 In vivo effects of bisphosphonates on the osteoclast mevalonate pathway. Endocrinology 141:4793-4796
    • (2000) Endocrinology , vol.141 , pp. 4793-4796
    • Fisher, J.E.1    Rodan, G.A.2    Reszka, A.A.3
  • 8
    • 0037204816 scopus 로고    scopus 로고
    • Inhibitory action of bisphosphonates on bone resorption does not involve the regulation of RANKL and OPG expression
    • Kim YH, Kim G-S, Baek J-H 2002 Inhibitory action of bisphosphonates on bone resorption does not involve the regulation of RANKL and OPG expression. Exp Mol Med 34:145-151
    • (2002) Exp Mol Med , vol.34 , pp. 145-151
    • Kim, Y.H.1    Kim, G.-S.2    Baek, J.-H.3
  • 9
    • 0027313988 scopus 로고
    • Early histomorphometric changes in response to parathyroid hormone therapy in osteoporosis: Evidence for de novo bone formation on quiescent cancellous surfaces
    • Hodsman AB, Steer BM 1993 Early histomorphometric changes in response to parathyroid hormone therapy in osteoporosis: evidence for de novo bone formation on quiescent cancellous surfaces. Bone 523-527
    • (1993) Bone , pp. 523-527
    • Hodsman, A.B.1    Steer, B.M.2
  • 10
    • 0029116964 scopus 로고
    • Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells
    • Dobnig H, Turner RT 1995 Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells. Endocrinology 136:3632-3638
    • (1995) Endocrinology , vol.136 , pp. 3632-3638
    • Dobnig, H.1    Turner, R.T.2
  • 11
    • 33144457259 scopus 로고    scopus 로고
    • A novel tetracycline labeling schedule for longitudinal evaluation of the short-term effects of anabolic therapy with a single iliac crest bone biopsy: Early actions of teriparatide
    • Lindsay R, Cosman F, Zhou H, Bostrom MP, Shen VW, Cruz JD, Nieves JW, Dempster DW 2006 A novel tetracycline labeling schedule for longitudinal evaluation of the short-term effects of anabolic therapy with a single iliac crest bone biopsy: early actions of teriparatide. J Bone Miner Res 21:366-373
    • (2006) J Bone Miner Res , vol.21 , pp. 366-373
    • Lindsay, R.1    Cosman, F.2    Zhou, H.3    Bostrom, M.P.4    Shen, V.W.5    Cruz, J.D.6    Nieves, J.W.7    Dempster, D.W.8
  • 12
  • 14
    • 0030962888 scopus 로고    scopus 로고
    • Parathyroid hormone exerts disparate effects on osteoblast differentiation depending on exposure time in rat osteoblastic cells
    • Ishizuya T, Yokose S, Hori M, Noda T, Suda T, Yoshiki S 1997 Parathyroid hormone exerts disparate effects on osteoblast differentiation depending on exposure time in rat osteoblastic cells. J Clin Invest 99:2961-2970
    • (1997) J Clin Invest , vol.99 , pp. 2961-2970
    • Ishizuya, T.1    Yokose, S.2    Hori, M.3    Noda, T.4    Suda, T.5    Yoshiki, S.6
  • 15
    • 0035063315 scopus 로고    scopus 로고
    • Parathyroid hormone added to established hormone therapy: Effects on vertebral fracture and maintenance of bone mass after PTH withdrawal
    • Cosman F, Nieves J, Woelfert L, Formica C, Gordon S, Shen V, Lindsay R 2001 Parathyroid hormone added to established hormone therapy: effects on vertebral fracture and maintenance of bone mass after PTH withdrawal. J Bone Miner Res 16:925-931
    • (2001) J Bone Miner Res , vol.16 , pp. 925-931
    • Cosman, F.1    Nieves, J.2    Woelfert, L.3    Formica, C.4    Gordon, S.5    Shen, V.6    Lindsay, R.7
  • 16
    • 23444435838 scopus 로고    scopus 로고
    • Daily and cyclic parathyroid hormone in women receiving alendronate alone for treatment
    • Cosman F, Nieves JW, Lucky MM, Zion M, Woelfert L, Lindsay R 2005 Daily and cyclic parathyroid hormone in women receiving alendronate alone for treatment. N Engl J Med 353:566-575
    • (2005) N Engl J Med , vol.353 , pp. 566-575
    • Cosman, F.1    Nieves, J.W.2    Lucky, M.M.3    Zion, M.4    Woelfert, L.5    Lindsay, R.6
  • 17
    • 33144482005 scopus 로고    scopus 로고
    • Effects of cyclic vs. daily PTH regimens on bone strength in association with bone density, biochemical markers and bone structure in mice
    • Iida-Klein A, Hughes C, Shen V, Moreno A, Lu SS, Dempster DW, Cosman F, Lindsay R 2006 Effects of cyclic vs. daily PTH regimens on bone strength in association with bone density, biochemical markers and bone structure in mice. J Bone Miner Res 21:274-282
    • (2006) J Bone Miner Res , vol.21 , pp. 274-282
    • Iida-Klein, A.1    Hughes, C.2    Shen, V.3    Moreno, A.4    Lu, S.S.5    Dempster, D.W.6    Cosman, F.7    Lindsay, R.8
  • 18
    • 33845995061 scopus 로고    scopus 로고
    • Effects of cyclic vs. daily PTH on murine bone structure and cellular activity
    • Iida-Klein A, Lu SS, Dempster DW, Cosman F, Lindsay R 2007 Effects of cyclic vs. daily PTH on murine bone structure and cellular activity. Bone 40:391-398
    • (2007) Bone , vol.40 , pp. 391-398
    • Iida-Klein, A.1    Lu, S.S.2    Dempster, D.W.3    Cosman, F.4    Lindsay, R.5
  • 19
    • 0141684971 scopus 로고    scopus 로고
    • Black DM, Greenspan SL, Ensrud KE, Palermo L, McGowan JA, Lang TF, Garnero P, Bouxsein ML, Bilezikian JP, Rosen CJ; PaTH Study Investigators 2003 The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis. N Engl J Med 349:1207-1215
    • Black DM, Greenspan SL, Ensrud KE, Palermo L, McGowan JA, Lang TF, Garnero P, Bouxsein ML, Bilezikian JP, Rosen CJ; PaTH Study Investigators 2003 The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis. N Engl J Med 349:1207-1215
  • 21
    • 3242762388 scopus 로고    scopus 로고
    • Differential effects of teriparatide onBMDafter treatment with raloxifene or alendronate
    • Ettinger B, San Martin J, Crans G, Pavo I 2004 Differential effects of teriparatide onBMDafter treatment with raloxifene or alendronate. J Bone Miner Res 19:745-751
    • (2004) J Bone Miner Res , vol.19 , pp. 745-751
    • Ettinger, B.1    San Martin, J.2    Crans, G.3    Pavo, I.4
  • 22
    • 0029091836 scopus 로고
    • The anabolic effect of human PTH(1-34) on bone formation is blunted when bone resorption is inhibited by the bisphosphonate - is activated resorption a prerequisite for the in vivo effect of PTH on formation in a remodeling system?
    • Delmas PD, Vergnaud P, Arlot ME, Pastoureau P, Meunier PJ, Nilssen MH 1995 The anabolic effect of human PTH(1-34) on bone formation is blunted when bone resorption is inhibited by the bisphosphonate - is activated resorption a prerequisite for the in vivo effect of PTH on formation in a remodeling system? Bone 16:603-610
    • (1995) Bone , vol.16 , pp. 603-610
    • Delmas, P.D.1    Vergnaud, P.2    Arlot, M.E.3    Pastoureau, P.4    Meunier, P.J.5    Nilssen, M.H.6
  • 25
    • 0037733123 scopus 로고    scopus 로고
    • New bone formation with teriparatide [human parathyroid hormone( 1-34)] is not retarded by long-term pretreatment with alendronate, estrogen, or raloxifene in ovariectomized rats
    • Ma YL, Bryant HU, Zeng Q, Schmidt A, Hoover J, Cole HW, Yao W, Jee WS, Sato M 2003 New bone formation with teriparatide [human parathyroid hormone( 1-34)] is not retarded by long-term pretreatment with alendronate, estrogen, or raloxifene in ovariectomized rats. Endocrinology 144:2008-2015
    • (2003) Endocrinology , vol.144 , pp. 2008-2015
    • Ma, Y.L.1    Bryant, H.U.2    Zeng, Q.3    Schmidt, A.4    Hoover, J.5    Cole, H.W.6    Yao, W.7    Jee, W.S.8    Sato, M.9
  • 26
    • 34548105034 scopus 로고    scopus 로고
    • Anabolic actions of PTH in bone: Role of osteoblast proliferation, differentiation, and combinatorial treatment with bisphosphonates
    • Pettway GJ, Meganck JA, Wei CL, Goldstein SA, McCauley, LK 2006 Anabolic actions of PTH in bone: role of osteoblast proliferation, differentiation, and combinatorial treatment with bisphosphonates. J Bone Miner Res 21(Suppl 1):S114
    • (2006) J Bone Miner Res , vol.21 , Issue.SUPPL. 1
    • Pettway, G.J.1    Meganck, J.A.2    Wei, C.L.3    Goldstein, S.A.4    McCauley, L.K.5
  • 27
    • 0037365442 scopus 로고    scopus 로고
    • Precision, accuracy, and reproducibility of dual x-ray absorptiometry measurements in mice in vivo
    • Iida-Klein A, Lu SS, Yokoyama K, Dempster DW, Nieves J, Lindsay R 2003 Precision, accuracy, and reproducibility of dual x-ray absorptiometry measurements in mice in vivo. J Clin Densitom 6:25-33
    • (2003) J Clin Densitom , vol.6 , pp. 25-33
    • Iida-Klein, A.1    Lu, S.S.2    Yokoyama, K.3    Dempster, D.W.4    Nieves, J.5    Lindsay, R.6
  • 29
    • 26044477471 scopus 로고    scopus 로고
    • Short-term continuous infusion of human parathyroid 1-34 fragment is catabolic with decreased trabecular connectivity density accompanied by hypercalcemia in C57BL/J6 mice
    • Iida-Klein A, Lu SS, Kapadia R, Burkhart M, Moreno A, Dempster DW, Lindsay R 2005 Short-term continuous infusion of human parathyroid 1-34 fragment is catabolic with decreased trabecular connectivity density accompanied by hypercalcemia in C57BL/J6 mice. J Endocrinol 186:549-557
    • (2005) J Endocrinol , vol.186 , pp. 549-557
    • Iida-Klein, A.1    Lu, S.S.2    Kapadia, R.3    Burkhart, M.4    Moreno, A.5    Dempster, D.W.6    Lindsay, R.7
  • 30
    • 33845934478 scopus 로고    scopus 로고
    • Co-treatment of PTH with osteoprotegerin or alendronate increases its anabolic effect on the skeleton of oophorectomized mice
    • Samadfam R, Xia Q, Goltzman D 2006 Co-treatment of PTH with osteoprotegerin or alendronate increases its anabolic effect on the skeleton of oophorectomized mice. J Bone Miner Res 22:55-63
    • (2006) J Bone Miner Res , vol.22 , pp. 55-63
    • Samadfam, R.1    Xia, Q.2    Goltzman, D.3
  • 32
    • 33749518855 scopus 로고    scopus 로고
    • Bisphosphonates suppress periosteal osteoblast activity independently of resorption in rat femur and tibia
    • Iwata K, Li J, Follet H, Phipps RJ, Burr DB 2006 Bisphosphonates suppress periosteal osteoblast activity independently of resorption in rat femur and tibia. Bone 39:1053-1058
    • (2006) Bone , vol.39 , pp. 1053-1058
    • Iwata, K.1    Li, J.2    Follet, H.3    Phipps, R.J.4    Burr, D.B.5
  • 33
    • 33750549653 scopus 로고    scopus 로고
    • Antiremodeling agents influence osteoblast activity differently in modeling and remodeling sites of canine rib
    • Allen MR, Follet H, Khurana M, Sato M, Burr DB 2006 Antiremodeling agents influence osteoblast activity differently in modeling and remodeling sites of canine rib. Calcif Tissue Int 79:255-261
    • (2006) Calcif Tissue Int , vol.79 , pp. 255-261
    • Allen, M.R.1    Follet, H.2    Khurana, M.3    Sato, M.4    Burr, D.B.5
  • 34
    • 34548108245 scopus 로고    scopus 로고
    • Bone formation in the periosteal, endocortical, and trabecular envelopes of the ilium of adult women
    • Bare S, Recker S, Recker R, Kimmel D 2005 Bone formation in the periosteal, endocortical, and trabecular envelopes of the ilium of adult women. J Bone Miner Res 20(Suppl 1):S274
    • (2005) J Bone Miner Res , vol.20 , Issue.SUPPL. 1
    • Bare, S.1    Recker, S.2    Recker, R.3    Kimmel, D.4
  • 35
    • 33646871267 scopus 로고    scopus 로고
    • Teriparatide increases bone formation in modeling and remodeling osteons and enhances IGF-II immunoreactivity in postmenopausal women with osteoporosis
    • Ma YL, Zeng Q, Donley DW, Ste-Marie L, Gallagher JC, Dalsky GP, Marcus R Eriksen EF 2006 Teriparatide increases bone formation in modeling and remodeling osteons and enhances IGF-II immunoreactivity in postmenopausal women with osteoporosis. J Bone Miner Res 21:855-864
    • (2006) J Bone Miner Res , vol.21 , pp. 855-864
    • Ma, Y.L.1    Zeng, Q.2    Donley, D.W.3    Ste-Marie, L.4    Gallagher, J.C.5    Dalsky, G.P.6    Marcus, R.7    Eriksen, E.F.8
  • 37
    • 0025324285 scopus 로고
    • Treatment of osteoporosis with human parathyroid peptide and observations on effect of sodium fluoride
    • Reeves J, Davies UM, Hesp R, McNally E, Katz D 1990 Treatment of osteoporosis with human parathyroid peptide and observations on effect of sodium fluoride. Br Med J 301:314-318
    • (1990) Br Med J , vol.301 , pp. 314-318
    • Reeves, J.1    Davies, U.M.2    Hesp, R.3    McNally, E.4    Katz, D.5
  • 38
    • 34248506476 scopus 로고    scopus 로고
    • Effects of a one-month treatment with PTH(1-34) on bone formation on cancellous, endocortical and periosteal surfaces of the human ilium
    • Lindsay R, Zhou H, Cosman F, Nieves J, Dempster DW, Hodsman A 2007 Effects of a one-month treatment with PTH(1-34) on bone formation on cancellous, endocortical and periosteal surfaces of the human ilium. J Bone Miner Res 22:495-502
    • (2007) J Bone Miner Res , vol.22 , pp. 495-502
    • Lindsay, R.1    Zhou, H.2    Cosman, F.3    Nieves, J.4    Dempster, D.W.5    Hodsman, A.6
  • 42
    • 21644456893 scopus 로고    scopus 로고
    • The effect of static torsion on the compressive strength of the spine: An in vitro analysis using a porcine spine model
    • Aultman CD, Drake JD, Callaghan JP, McGill SM 2004 The effect of static torsion on the compressive strength of the spine: an in vitro analysis using a porcine spine model. Spine 29: E304-E309
    • (2004) Spine , vol.29
    • Aultman, C.D.1    Drake, J.D.2    Callaghan, J.P.3    McGill, S.M.4
  • 43
    • 34548072691 scopus 로고    scopus 로고
    • Overview of osteoporosis: Pathophysiology and determinants of bone strength
    • Aebi M, Gunzburg R, Szpalski MP, eds, Heidelberg: Springer-Berlin;
    • Bono CM, Einhorn TA 2005 Overview of osteoporosis: pathophysiology and determinants of bone strength. In: Aebi M, Gunzburg R, Szpalski MP, eds. The aging spine. Heidelberg: Springer-Berlin; 8-14
    • (2005) The aging spine , pp. 8-14
    • Bono, C.M.1    Einhorn, T.A.2
  • 44
    • 34250854249 scopus 로고    scopus 로고
    • Pretreatment with anticatabolic agents blunts but does not eliminate the skeletal anabolic response to parathyroid hormone in oophorectomized mice
    • Samadfam R, Xia Q, Golzman D 2007 Pretreatment with anticatabolic agents blunts but does not eliminate the skeletal anabolic response to parathyroid hormone in oophorectomized mice. Endocrinology 148:2778-2787
    • (2007) Endocrinology , vol.148 , pp. 2778-2787
    • Samadfam, R.1    Xia, Q.2    Golzman, D.3
  • 45
    • 0023871244 scopus 로고
    • Effects of a synthetic peptide of a parathyroid hormone-related protein on calcium homeostasis, renal tubular calcium reabsorption, and bone metabolism in vivo and in vitro rodents
    • Yates AJP, Gutierrez GE, Smolens P, Travis PS, Katz MS, Aufdemorte TB, Boyce BF, Hymer TK, Poser JW, Mundy GR 1988 Effects of a synthetic peptide of a parathyroid hormone-related protein on calcium homeostasis, renal tubular calcium reabsorption, and bone metabolism in vivo and in vitro rodents. J Clin Invest 88:932-938
    • (1988) J Clin Invest , vol.88 , pp. 932-938
    • Yates, A.J.P.1    Gutierrez, G.E.2    Smolens, P.3    Travis, P.S.4    Katz, M.S.5    Aufdemorte, T.B.6    Boyce, B.F.7    Hymer, T.K.8    Poser, J.W.9    Mundy, G.R.10
  • 46
    • 0029874050 scopus 로고    scopus 로고
    • Sequential effects of chronic human PTH (1- 84) treatment of estrogen deficiency osteopenia in the rat
    • Mitlak BH, Burdette-Miller P, Schoenfeld D, Neer RM 1996 Sequential effects of chronic human PTH (1- 84) treatment of estrogen deficiency osteopenia in the rat. J Bone Miner Res 11:430-439
    • (1996) J Bone Miner Res , vol.11 , pp. 430-439
    • Mitlak, B.H.1    Burdette-Miller, P.2    Schoenfeld, D.3    Neer, R.M.4


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