Contribution of the S5-pore-S6 domain to the gating characteristics of the cation channels TRPM2 and TRPM8

Journal of Biological Chemistry

Volumn 285, Issue 35, 2010, Pages 26806-26814

  Kühn, Frank J P ^a   Witschas, Katja ^a   Kühn, Cornelia ^a   Lückhoff, Andreas ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADP-RIBOSE; C TERMINUS; CATION CHANNELS; COLD TEMPERATURES; DEPENDENT PROCESS; EXTRACELLULAR; GAIN INSIGHT; HIGH CONCENTRATION; HYPERPOLARIZATION; IN-CONTROL; INTRACELLULAR CA; MEMBRANE POTENTIALS; SINGLE CHANNEL RECORDING; SINGLE-CHANNEL; VOLTAGE SENSITIVITY; VOLTAGE SENSOR; WILD TYPES;

CALCIUM; HYDROGEN; HYDROGEN PEROXIDE; OXIDATION; POSITIVE IONS;

ENZYME ACTIVITY;

1 (2 HYDROXYPHENYL) 4 (3 NITROPHENYL) 1,2,3,6 TETRAHYDROPYRIMIDIN 2 ONE; ADENOSINE DIPHOSPHATE RIBOSE; CALCIUM ION; HYDROGEN PEROXIDE; MENTHOL; REAGENT; TRANSIENT RECEPTOR POTENTIAL CHANNEL M2; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE POTENTIAL; CELL STRAIN HEK293; CHANNEL GATING; CHIMERA; COLD SENSITIVITY; CONTROLLED STUDY; EXTRACELLULAR CALCIUM; HYPERPOLARIZATION; ION CURRENT; MOLECULAR INTERACTION; POROSITY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; REGULATORY MECHANISM; WILD TYPE;

ADENOSINE DIPHOSPHATE RIBOSE; ANTIPRURITICS; CALCIUM; CELL LINE; COLD TEMPERATURE; HUMANS; HYDROGEN PEROXIDE; ION CHANNEL GATING; MEMBRANE POTENTIALS; MENTHOL; OXIDANTS; PROTEIN STRUCTURE, TERTIARY; PYRIMIDINONES; RECOMBINANT FUSION PROTEINS; TRPM CATION CHANNELS;

EID: 77956243271     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.109975     Document Type: Article

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