-
1
-
-
77956244821
-
Method of treating organophosphorous poisoning
-
inventors; University of Maryland, Baltimore, assignee. International Patent Application PCT/US05/33789. 2005 Sept 23
-
Albuquerque EX, Adler M, and Pereira EFR (2005) inventors; University of Maryland, Baltimore, assignee. Method of treating organophosphorous poisoning. International Patent Application PCT/US05/33789. 2005 Sept 23.
-
(2005)
-
-
Albuquerque, E.X.1
Adler, M.2
Pereira, E.F.R.3
-
2
-
-
0022337137
-
Multiple actions of anticholinesterase agents on chemo-sensitive synapses: Molecular basis for prophylaxis and treatment of organophosphate poisoning
-
Albuquerque EX, Deshpande SS, Kawabuchi M, Aracava Y, Idriss M, Rickett DL, and Boyne AF (1985) Multiple actions of anticholinesterase agents on chemo-sensitive synapses: molecular basis for prophylaxis and treatment of organophosphate poisoning. Fundam Appl Toxicol 5:S182-S203.
-
(1985)
Fundam Appl Toxicol
, vol.5
-
-
Albuquerque, E.X.1
Deshpande, S.S.2
Kawabuchi, M.3
Aracava, Y.4
Idriss, M.5
Rickett, D.L.6
Boyne, A.F.7
-
4
-
-
33748366780
-
Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents
-
Albuquerque EX, Pereira EFR, Aracava Y, Fawcett WP, Oliveira M, Randall WR, Hamilton TA, Kan RK, Romano JA Jr, and Adler M (2006) Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents. Proc Natl Acad Sci USA 103:13220-13225.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 13220-13225
-
-
Albuquerque, E.X.1
Pereira, E.F.R.2
Aracava, Y.3
Fawcett, W.P.4
Oliveira, M.5
Randall, W.R.6
Hamilton, T.A.7
Kan, R.K.8
Romano Jr., J.A.9
Adler, M.10
-
5
-
-
59149103232
-
A single in vivo application of cholinesterase inhibitors has neuron type-specific effects on nicotinic receptor activity in guinea pig hippocampus
-
Alkondon M, Aracava Y, Pereira EFR, and Albuquerque EX (2009) A single in vivo application of cholinesterase inhibitors has neuron type-specific effects on nicotinic receptor activity in guinea pig hippocampus. J Pharmacol Exp Ther 328:69-82.
-
(2009)
J Pharmacol Exp Ther
, vol.328
, pp. 69-82
-
-
Alkondon, M.1
Aracava, Y.2
Pereira, E.F.R.3
Albuquerque, E.X.4
-
6
-
-
0033815626
-
Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus
-
Alkondon M, Pereira EFR, Almeida LEF, Randall WR, and Albuquerque EX (2000) Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus. Neuropharmacology 39:2726-2739.
-
(2000)
Neuropharmacology
, vol.39
, pp. 2726-2739
-
-
Alkondon, M.1
Pereira, E.F.R.2
Almeida, L.E.F.3
Randall, W.R.4
Albuquerque, E.X.5
-
7
-
-
73349083978
-
Effectiveness of donepezil, rivastigmine, and (±)huperzine A in counteracting the acute toxicity of organophosphorus nerve agents: Comparison with galantamine
-
Aracava Y, Pereira EFR, Akkerman M, Adler M, and Albuquerque EX (2009) Effectiveness of donepezil, rivastigmine, and (±)huperzine A in counteracting the acute toxicity of organophosphorus nerve agents: comparison with galantamine. J Pharmacol Exp Ther 331:1014-1024.
-
(2009)
J Pharmacol Exp Ther
, vol.331
, pp. 1014-1024
-
-
Aracava, Y.1
Pereira, E.F.R.2
Akkerman, M.3
Adler, M.4
Albuquerque, E.X.5
-
8
-
-
0027473711
-
Cholinergic modulation of synaptic inhibition in the guinea pig hippocampus in vitro: Excitation of GABAergic interneurons and inhibition of GABA release
-
Behrends JC and ten Bruggencate G (1993) Cholinergic modulation of synaptic inhibition in the guinea pig hippocampus in vitro: excitation of GABAergic interneurons and inhibition of GABA release. J Neurophysiol 69:626-629.
-
(1993)
J Neurophysiol
, vol.69
, pp. 626-629
-
-
Behrends, J.C.1
Ten Bruggencate, G.2
-
9
-
-
0021921141
-
Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy
-
Ben-Ari Y (1985) Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy. Neuroscience 14:375-403.
-
(1985)
Neuroscience
, vol.14
, pp. 375-403
-
-
Ben-Ari, Y.1
-
10
-
-
39349088308
-
Presynaptic signaling by heterotrimeric G-proteins
-
Brown DA and Sihra TS (2008) Presynaptic signaling by heterotrimeric G-proteins. Handb Exp Pharmacol 184:207-260.
-
(2008)
Handb Exp Pharmacol
, vol.184
, pp. 207-260
-
-
Brown, D.A.1
Sihra, T.S.2
-
11
-
-
0034759619
-
Hippocampal GABAergic interneurons: A physiological perspective
-
Buzsáki G (2001) Hippocampal GABAergic interneurons: a physiological perspective. Neurochem Res 26:899-905.
-
(2001)
Neurochem Res
, vol.26
, pp. 899-905
-
-
Buzsáki, G.1
-
12
-
-
0025295961
-
Soman- or kainic acid-induced convulsions decrease muscarinic receptors but not benzodiazepine receptors
-
Churchill L, Pazdernik TL, Cross RS, Nelson SR, and Samson FE (1990) Soman- or kainic acid-induced convulsions decrease muscarinic receptors but not benzodiazepine receptors. Neurotoxicology 11:57-71.
-
(1990)
Neurotoxicology
, vol.11
, pp. 57-71
-
-
Churchill, L.1
Pazdernik, T.L.2
Cross, R.S.3
Nelson, S.R.4
Samson, F.E.5
-
13
-
-
13444288245
-
Cholinergic modulation of hippocampal cells and circuits
-
Cobb SR and Davies CH (2005) Cholinergic modulation of hippocampal cells and circuits. J Physiol 562:81-88.
-
(2005)
J Physiol
, vol.562
, pp. 81-88
-
-
Cobb, S.R.1
Davies, C.H.2
-
14
-
-
35448951405
-
Muscarinic receptor dysfunction induced by exposure to low levels of soman vapor
-
Dabisch PA, Horsmon MS, Muse WT, Mioduszewski RJ, and Thomson S (2007) Muscarinic receptor dysfunction induced by exposure to low levels of soman vapor. Toxicol Sci 100:281-289.
-
(2007)
Toxicol Sci
, vol.100
, pp. 281-289
-
-
Dabisch, P.A.1
Horsmon, M.S.2
Muse, W.T.3
Mioduszewski, R.J.4
Thomson, S.5
-
15
-
-
0034760772
-
Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: Supersensitivity of acetylcholinesterase knockout mouse to VX lethality
-
Duysen EG, Li B, Xie W, Schopfer LM, Anderson RS, Broomfield CA, and Lockridge O (2001) Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality. J Pharmacol Exp Ther 299:528-535.
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 528-535
-
-
Duysen, E.G.1
Li, B.2
Xie, W.3
Schopfer, L.M.4
Anderson, R.S.5
Broomfield, C.A.6
Lockridge, O.7
-
16
-
-
0032873707
-
Memory impairment after soman intoxication in rat: Correlation with central neuropathology. Improvement with anticholinergic and antiglutamatergic therapeutics
-
Filliat P, Baubichon D, Burckhart MF, Pernot-Marino I, Foquin A, Masqueliez C, Perrichon C, Carpentier P, and Lallement G (1999) Memory impairment after soman intoxication in rat: correlation with central neuropathology. Improvement with anticholinergic and antiglutamatergic therapeutics. Neurotoxicology 20:535-549.
-
(1999)
Neurotoxicology
, vol.20
, pp. 535-549
-
-
Filliat, P.1
Baubichon, D.2
Burckhart, M.F.3
Pernot-Marino, I.4
Foquin, A.5
Masqueliez, C.6
Perrichon, C.7
Carpentier, P.8
Lallement, G.9
-
17
-
-
0025069827
-
Neurotransmitter changes in guinea-pig brain regions following soman intoxication
-
Fosbraey P, Wetherell JR, and French MC (1990) Neurotransmitter changes in guinea-pig brain regions following soman intoxication. J Neurochem 54:72-79.
-
(1990)
J Neurochem
, vol.54
, pp. 72-79
-
-
Fosbraey, P.1
Wetherell, J.R.2
French, M.C.3
-
18
-
-
2942538498
-
Two distinct classes of muscarinic action on hippocampal inhibitory synapses: M2-mediated direct suppression and M1/M3-mediated indirect suppression through endocannabinoid signaling
-
Fukudome Y, Ohno-Shosaku T, Matsui M, Omori Y, Fukaya M, Tsubokawa H, Taketo MM, Watanabe M, Manabe T, and Kano M (2004) Two distinct classes of muscarinic action on hippocampal inhibitory synapses: M2-mediated direct suppression and M1/M3-mediated indirect suppression through endocannabinoid signaling. Eur J Neurosci 19:2682-2692.
-
(2004)
Eur J Neurosci
, vol.19
, pp. 2682-2692
-
-
Fukudome, Y.1
Ohno-Shosaku, T.2
Matsui, M.3
Omori, Y.4
Fukaya, M.5
Tsubokawa, H.6
Taketo, M.M.7
Watanabe, M.8
Manabe, T.9
Kano, M.10
-
19
-
-
74249112977
-
Magnetic resonance imaging reveals that galantamine prevents structural brain damage induced by an acute exposure of guinea pigs to soman
-
Gullapalli RP, Aracava Y, Zhuo J, Helal Neto E, Wang J, Makris G, Merchenthaler I, Pereira EFR, and Albuquerque EX (2010) Magnetic resonance imaging reveals that galantamine prevents structural brain damage induced by an acute exposure of guinea pigs to soman. Neurotoxicology 31:67-76.
-
(2010)
Neurotoxicology
, vol.31
, pp. 67-76
-
-
Gullapalli, R.P.1
Aracava, Y.2
Zhuo, J.3
Helal Neto, E.4
Wang, J.5
Makris, G.6
Merchenthaler, I.7
Pereira, E.F.R.8
Albuquerque, E.X.9
-
20
-
-
0242653505
-
Distinct interneuron types express m2 muscarinic receptor immunoreactivity on their dendrites or axon terminals in the hippocampus
-
Hájos N, Papp EC, Acsády L, Levey AI, and Freund TF (1998) Distinct interneuron types express m2 muscarinic receptor immunoreactivity on their dendrites or axon terminals in the hippocampus. Neuroscience 82:355-376.
-
(1998)
Neuroscience
, vol.82
, pp. 355-376
-
-
Hájos, N.1
Papp, E.C.2
Acsády, L.3
Levey, A.I.4
Freund, T.F.5
-
21
-
-
33744982075
-
Nicotinic mechanisms contribute to soman-induced symptoms and lethality
-
Hassel B (2006) Nicotinic mechanisms contribute to soman-induced symptoms and lethality. Neurotoxicology 27:501-507.
-
(2006)
Neurotoxicology
, vol.27
, pp. 501-507
-
-
Hassel, B.1
-
22
-
-
0028326401
-
Chlorpyrifos oxon binds directly to muscarinic receptors and inhibits cAMP accumulation in rat striatum
-
Huff RA, Corcoran JJ, Anderson JK, and Abou-Donia MB (1994) Chlorpyrifos oxon binds directly to muscarinic receptors and inhibits cAMP accumulation in rat striatum. J Pharmacol Exp Ther 269:329-335.
-
(1994)
J Pharmacol Exp Ther
, vol.269
, pp. 329-335
-
-
Huff, R.A.1
Corcoran, J.J.2
Anderson, J.K.3
Abou-Donia, M.B.4
-
23
-
-
0003633755
-
-
Institute of Laboratory Animal Resources 7th ed, Institute of Laboratory Animal Resources, Commission on Life Science, National Research Council, Washington, DC
-
Institute of Laboratory Animal Resources (1996) Guide for the Care and Use of Laboratory Animals, 7th ed, Institute of Laboratory Animal Resources, Commission on Life Science, National Research Council, Washington, DC.
-
(1996)
Guide for the Care and Use of Laboratory Animals
-
-
-
24
-
-
0037339003
-
Adenosine A1 receptor-mediated presynaptic inhibition of GABAergic transmission in immature rat hippocampal CA1 neurons
-
Jeong HJ, Jang IS, Nabekura J, and Akaike N (2003) Adenosine A1 receptor-mediated presynaptic inhibition of GABAergic transmission in immature rat hippocampal CA1 neurons. J Neurophysiol 89:1214-1222.
-
(2003)
J Neurophysiol
, vol.89
, pp. 1214-1222
-
-
Jeong, H.J.1
Jang, I.S.2
Nabekura, J.3
Akaike, N.4
-
25
-
-
0033622115
-
Distinct internalization of M2 muscarinic acetylcholine receptors confers selective and long-lasting desensitization of signaling to phospholipase C
-
Krudewig R, Langer B, Vögler O, Markschies N, Erl M, Jakobs KH, and van Koppen CJ (2000) Distinct internalization of M2 muscarinic acetylcholine receptors confers selective and long-lasting desensitization of signaling to phospholipase C. J Neurochem 74:1721-1730.
-
(2000)
J Neurochem
, vol.74
, pp. 1721-1730
-
-
Krudewig, R.1
Langer, B.2
Vögler, O.3
Markschies, N.4
Erl, M.5
Jakobs, K.H.6
Van Koppen, C.J.7
-
26
-
-
0026015303
-
Effects of some organophosphorus compounds on the binding of a radioligand (8-cyclopentyl 1, 3-[3H]dipropylxanthine) to adenosine receptors in ovine cardiac membranes
-
Lau WM, Szilagyi M, and Freeman SE (1991) Effects of some organophosphorus compounds on the binding of a radioligand (8-cyclopentyl 1, 3-[3H]dipropylxanthine) to adenosine receptors in ovine cardiac membranes. J Appl Toxicol 11:411-414.
-
(1991)
J Appl Toxicol
, vol.11
, pp. 411-414
-
-
Lau, W.M.1
Szilagyi, M.2
Freeman, S.E.3
-
27
-
-
0031919243
-
Differential recovery of acetylcholinesterase in guinea pig muscle and brain regions after soman treatment
-
Lintern MC, Wetherell JR, and Smith ME (1998) Differential recovery of acetylcholinesterase in guinea pig muscle and brain regions after soman treatment. Hum Exp Toxicol 17:157-162.
-
(1998)
Hum Exp Toxicol
, vol.17
, pp. 157-162
-
-
Lintern, M.C.1
Wetherell, J.R.2
Smith, M.E.3
-
28
-
-
0034732104
-
Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease
-
DOI 10.1016/S0014-2999(00)00093-5, PII S0014299900000935
-
Maelicke A and Albuquerque EX (2000) Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease. Eur J Pharmacol 393:165-170. (Pubitemid 30193413)
-
(2000)
European Journal of Pharmacology
, vol.393
, Issue.1-3
, pp. 165-170
-
-
Maelicke, A.1
Albuquerque, E.X.2
-
29
-
-
34548024623
-
Neuronal structures involved in the induction and propagation of seizures caused by nerve agents: Implications for medical treatment
-
Myhrer T (2007) Neuronal structures involved in the induction and propagation of seizures caused by nerve agents: implications for medical treatment. Toxicology 239:1-14.
-
(2007)
Toxicology
, vol.239
, pp. 1-14
-
-
Myhrer, T.1
-
30
-
-
7444232206
-
Soman-induced convulsions in rats terminated with pharmacological agents after 45 min: Neuropathology and cognitive performance
-
Myhrer T, Andersen JM, Nguyen NH, and Aas P (2005) Soman-induced convulsions in rats terminated with pharmacological agents after 45 min: neuropathology and cognitive performance. Neurotoxicology 26:39-48.
-
(2005)
Neurotoxicology
, vol.26
, pp. 39-48
-
-
Myhrer, T.1
Andersen, J.M.2
Nguyen, N.H.3
Aas, P.4
-
31
-
-
0019882992
-
Minireview. Kainic acid as a tool for the study of temporal lobe epilepsy
-
Nadler JV (1981) Minireview. Kainic acid as a tool for the study of temporal lobe epilepsy. Life Sci 29:2031-2042.
-
(1981)
Life Sci
, vol.29
, pp. 2031-2042
-
-
Nadler, J.V.1
-
32
-
-
33846247849
-
Nerve agents
-
Newmark J (2007) Nerve agents. Neurologist 13:20-32.
-
(2007)
Neurologist
, vol.13
, pp. 20-32
-
-
Newmark, J.1
-
33
-
-
61349089693
-
Novel medical countermeasure for organophosphorus intoxication: Connection to Alzheimer's disease and dementia
-
(Romano JA Jr, Lukey BJ, and Salem H eds) CRC Press, Boca Raton, FL
-
Pereira EFR, Burt DR, Aracava Y, Kan RK, Hamilton TA, Romano JA Jr, Adler M, and Albuquerque EX (2008) Novel medical countermeasure for organophosphorus intoxication: connection to Alzheimer's disease and dementia, in Chemical Warfare Agents (Romano JA Jr, Lukey BJ, and Salem H eds) pp 219-232, CRC Press, Boca Raton, FL.
-
(2008)
Chemical Warfare Agents
, pp. 219-232
-
-
Pereira, E.F.R.1
Burt, D.R.2
Aracava, Y.3
Kan, R.K.4
Hamilton, T.A.5
Romano Jr., J.A.6
Adler, M.7
Albuquerque, E.X.8
-
34
-
-
0036891169
-
Unconventional ligands and modulators of nicotinic receptors
-
Pereira EFR, Hilmas C, Santos MD, Alkondon M, Maelicke A, and Albuquerque EX (2002) Unconventional ligands and modulators of nicotinic receptors. J Neurobiol 53:479-500.
-
(2002)
J Neurobiol
, vol.53
, pp. 479-500
-
-
Pereira, E.F.R.1
Hilmas, C.2
Santos, M.D.3
Alkondon, M.4
Maelicke, A.5
Albuquerque, E.X.6
-
35
-
-
15744364468
-
Long-term effects of diazepam and phenobarbital treatment during development on GABA receptors, transporters and glutamic acid decarboxylase
-
Raol YH, Zhang G, Budreck EC, and Brooks-Kayal AR (2005) Long-term effects of diazepam and phenobarbital treatment during development on GABA receptors, transporters and glutamic acid decarboxylase. Neuroscience 132:399-407.
-
(2005)
Neuroscience
, vol.132
, pp. 399-407
-
-
Raol, Y.H.1
Zhang, G.2
Budreck, E.C.3
Brooks-Kayal, A.R.4
-
36
-
-
0037214547
-
Low concentrations of pyridostigmine prevents somaninduced inhibition of GABAergic transmission in the central nervous system: Involvement of muscarinic receptors
-
Santos MD, Pereira EFR, Aracava Y, Castro NG, Fawcett WP, Randall WR, and Albuquerque EX (2003) Low concentrations of pyridostigmine prevents somaninduced inhibition of GABAergic transmission in the central nervous system: involvement of muscarinic receptors. J Pharmacol Exp Ther 304:254-265.
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 254-265
-
-
Santos, M.D.1
Pereira, E.F.R.2
Aracava, Y.3
Castro, N.G.4
Fawcett, W.P.5
Randall, W.R.6
Albuquerque, E.X.7
-
37
-
-
0030839411
-
Neurochemical mechanisms in soman-induced seizures
-
Shih TM and McDonough JH Jr (1997) Neurochemical mechanisms in soman-induced seizures. J Appl Toxicol 17:255-264.
-
(1997)
J Appl Toxicol
, vol.17
, pp. 255-264
-
-
Shih, T.M.1
McDonough Jr., J.H.2
-
38
-
-
0033231230
-
Triggering of soman-induced seizures in rats: Multiparametric analysis with special correlation between enzymatic, neurochemical and electrophysiological data
-
Tonduli LS, Testylier G, Marino IP, and Lallement G (1999) Triggering of soman-induced seizures in rats: multiparametric analysis with special correlation between enzymatic, neurochemical and electrophysiological data. J Neurosci Res 58:464-473.
-
(1999)
J Neurosci Res
, vol.58
, pp. 464-473
-
-
Tonduli, L.S.1
Testylier, G.2
Marino, I.P.3
Lallement, G.4
-
39
-
-
72849124697
-
The direct relationship between inhibitory currents and local field potentials
-
Trevelyan AJ (2009) The direct relationship between inhibitory currents and local field potentials. J Neurosci 29:15299-15307.
-
(2009)
J Neurosci
, vol.29
, pp. 15299-15307
-
-
Trevelyan, A.J.1
-
40
-
-
0021175775
-
Behavioral changes in the rat after low doses of cholinesterase inhibitors
-
Wolthuis OL and Vanwersch RA (1984) Behavioral changes in the rat after low doses of cholinesterase inhibitors. Fundam Appl Toxicol 4:S195-S208.
-
(1984)
Fundam Appl Toxicol
, vol.4
-
-
Wolthuis, O.L.1
Vanwersch, R.A.2
-
41
-
-
0025941928
-
Cholinergic systems in the mammalian brain and spinal cord
-
Woolf NJ (1991) Cholinergic systems in the mammalian brain and spinal cord. Prog Neurobiol 37:475-524.
-
(1991)
Prog Neurobiol
, vol.37
, pp. 475-524
-
-
Woolf, N.J.1
|