메뉴 건너뛰기




Volumn 54, Issue 4, 2004, Pages 943-949

KRIT1/Cerebral Cavernous Malformation 1 Protein Localizes to Vascular Endothelium, Astrocytes, and Pyramidal Cells of the Adult Human Cerebral Cortex

Author keywords

Astrocytes; Blood brain barrier; Cerebral cavernous malformation; Endothelium; KRIT1

Indexed keywords

INTEGRIN; INTEGRIN CYTOPLASMIC DOMAIN ASSOCIATED PROTEIN 1ALPHA; MICROTUBULE PROTEIN; PROTEIN KRIT1; UNCLASSIFIED DRUG;

EID: 12144290066     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.NEU.0000114512.59624.A5     Document Type: Article
Times cited : (57)

References (31)
  • 3
    • 0030924021 scopus 로고    scopus 로고
    • ICAP-1, a novel β1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of β 1 integrin
    • Chang DD, Wong C, Smith H, Liu J: ICAP-1, a novel β1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of β1 integrin. J Cell Biol 138:1149-1157, 1997.
    • (1997) J Cell Biol , vol.138 , pp. 1149-1157
    • Chang, D.D.1    Wong, C.2    Smith, H.3    Liu, J.4
  • 4
    • 0037090688 scopus 로고    scopus 로고
    • Cerebral cavernous malformation: Novel mutation in a Chinese family and evidence for heterogeneity
    • Chen DH, Lipe HP, Qin Z, Bird TD: Cerebral cavernous malformation: Novel mutation in a Chinese family and evidence for heterogeneity. J Neurol Sci 196:91-96, 2002.
    • (2002) J Neurol Sci , vol.196 , pp. 91-96
    • Chen, D.H.1    Lipe, H.P.2    Qin, Z.3    Bird, T.D.4
  • 5
    • 0036726875 scopus 로고    scopus 로고
    • Vertebral hemangiomas associated with familial cerebral cavernous malformation: Segmental disease expression-Case report
    • Clatterbuck RE, Cohen B, Gailloud P, Murphy K, Rigamonti D: Vertebral hemangiomas associated with familial cerebral cavernous malformation: Segmental disease expression-Case report. J Neurosurg 97:227-230, 2002.
    • (2002) J Neurosurg , vol.97 , pp. 227-230
    • Clatterbuck, R.E.1    Cohen, B.2    Gailloud, P.3    Murphy, K.4    Rigamonti, D.5
  • 6
    • 0034925464 scopus 로고    scopus 로고
    • Ultrastructural and immunocytochemical evidence that an incompetent blood-brain barrier is related to the pathophysiology of cavernous malformations
    • Clatterbuck RE, Eberhart CG, Crain BJ, Rigamonti D: Ultrastructural and immunocytochemical evidence that an incompetent blood-brain barrier is related to the pathophysiology of cavernous malformations. J Neurol Neurosurg Psychiatry 71:188-192, 2001.
    • (2001) J Neurol Neurosurg Psychiatry , vol.71 , pp. 188-192
    • Clatterbuck, R.E.1    Eberhart, C.G.2    Crain, B.J.3    Rigamonti, D.4
  • 7
    • 0036128428 scopus 로고    scopus 로고
    • A novel KRIT1/CCM 1 truncating mutation in a patient with cerebral and retinal cavernous angiomas
    • Couteulx SL, Brezin AP, Fontaine B, Tournier-Lasserve E, Labauge P: A novel KRIT1/CCM1 truncating mutation in a patient with cerebral and retinal cavernous angiomas. Arch Ophthalmol 120:217-218, 2002.
    • (2002) Arch Ophthalmol , vol.120 , pp. 217-218
    • Couteulx, S.L.1    Brezin, A.P.2    Fontaine, B.3    Tournier-Lasserve, E.4    Labauge, P.5
  • 10
    • 0036768349 scopus 로고    scopus 로고
    • Krit1/cerebral cavernous malformation 1 mRNA is preferentially expressed in neurons and epithelial cells in embryo and adult
    • Denier C, Gasc JM, Chapon F, Domenga V, Lescoat C, Joutel A, Toumier-Lasserve E: Krit1/cerebral cavernous malformation 1 mRNA is preferentially expressed in neurons and epithelial cells in embryo and adult. Mech Dev 117:363-367, 2002.
    • (2002) Mech Dev , vol.117 , pp. 363-367
    • Denier, C.1    Gasc, J.M.2    Chapon, F.3    Domenga, V.4    Lescoat, C.5    Joutel, A.6    Toumier-Lasserve, E.7
  • 11
    • 0034702087 scopus 로고    scopus 로고
    • KRIT1 is mutated in hyperkeratotic cutaneous capillary-venous malformation associated with cerebral capillary malformation
    • Eerola I, Plate KH, Spiegel R, Boon LM, Mulliken JB, Vikkula M: KRIT1 is mutated in hyperkeratotic cutaneous capillary-venous malformation associated with cerebral capillary malformation. Hum Mol Genet 9:1351-1355, 2000.
    • (2000) Hum Mol Genet , vol.9 , pp. 1351-1355
    • Eerola, I.1    Plate, K.H.2    Spiegel, R.3    Boon, L.M.4    Mulliken, J.B.5    Vikkula, M.6
  • 13
    • 0036945852 scopus 로고    scopus 로고
    • Mutation and expression analysis of the KRIT1 gene associated with cerebral cavernous malformations (CCM1)
    • Kehrer-Sawatzki H, Wilda M, Braun VM, Richter HP, Hameister H: Mutation and expression analysis of the KRIT1 gene associated with cerebral cavernous malformations (CCM1). Acta Neuropathol (Berl) 104:231-240, 2002.
    • (2002) Acta Neuropathol (Berl) , vol.104 , pp. 231-240
    • Kehrer-Sawatzki, H.1    Wilda, M.2    Braun, V.M.3    Richter, H.P.4    Hameister, H.5
  • 14
    • 0024600222 scopus 로고
    • A ras-related gene with transformation suppressor activity
    • Kitayama H, Sugimoto Y, Matsuzaki T, Ikawa Y, Noda M: A ras-related gene with transformation suppressor activity. Cell 56:77-84, 1989.
    • (1989) Cell , vol.56 , pp. 77-84
    • Kitayama, H.1    Sugimoto, Y.2    Matsuzaki, T.3    Ikawa, Y.4    Noda, M.5
  • 15
    • 0037083415 scopus 로고    scopus 로고
    • Rap 1 GTPase regulation of adherens junction positioning and cell adhesion
    • Knox AL, Brown NH: Rap1 GTPase regulation of adherens junction positioning and cell adhesion. Science 295:1285-1288, 2002.
    • (2002) Science , vol.295 , pp. 1285-1288
    • Knox, A.L.1    Brown, N.H.2
  • 17
    • 0342748427 scopus 로고    scopus 로고
    • Spanish families with cerebral cavernous angioma do not bear 742C→T Hispanic American mutation of the KRIT1 gene
    • letter
    • Lucas M, Solano F, Zayas M.D., Garcia-Moreno JM, Gamero MA, Costa AF, Izquierdo G: Spanish families with cerebral cavernous angioma do not bear 742C→T Hispanic American mutation of the KRIT1 gene. Ann Neurol 47:836, 2000 (letter).
    • (2000) Ann Neurol , vol.47 , pp. 836
    • Lucas, M.1    Solano, F.2    Zayas, M.D.3    Garcia-Moreno, J.M.4    Gamero, M.A.5    Costa, A.F.6    Izquierdo, G.7
  • 23
    • 0030761145 scopus 로고    scopus 로고
    • Association of Krev-1/rapla with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22
    • Serebriiskii I, Estojak J, Sonoda G, Testa JR, Golemis EA: Association of Krev-1/rapla with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22. Oncogene 15:1043-1049, 1997.
    • (1997) Oncogene , vol.15 , pp. 1043-1049
    • Serebriiskii, I.1    Estojak, J.2    Sonoda, G.3    Testa, J.R.4    Golemis, E.A.5
  • 25
    • 0036097023 scopus 로고    scopus 로고
    • Kritl missense mutations lead to splicing errors in cerebral cavernous malformation
    • Verlaan DJ, Siegel AM, Rouleau GA: Kritl missense mutations lead to splicing errors in cerebral cavernous malformation. Am J Hum Genet 70:1564-1567, 2002.
    • (2002) Am J Hum Genet , vol.70 , pp. 1564-1567
    • Verlaan, D.J.1    Siegel, A.M.2    Rouleau, G.A.3
  • 26
    • 0036627211 scopus 로고    scopus 로고
    • Tight junctions of the blood-brain barrier: Development, composition and regulation
    • Wolburg H, Lippoldt A: Tight junctions of the blood-brain barrier: Development, composition and regulation. Vasc Pharmacol 38:323-337, 2002.
    • (2002) Vasc Pharmacol , vol.38 , pp. 323-337
    • Wolburg, H.1    Lippoldt, A.2
  • 27
    • 0034517320 scopus 로고    scopus 로고
    • Ultrastructural pathological features of cerebrovascular malformations: A preliminary report
    • Wong JH, Awad IA, Kim JH: Ultrastructural pathological features of cerebrovascular malformations: A preliminary report. Neurosurgery 46:1454-1459, 2000.
    • (2000) Neurosurgery , vol.46 , pp. 1454-1459
    • Wong, J.H.1    Awad, I.A.2    Kim, J.H.3
  • 28
    • 0037084658 scopus 로고    scopus 로고
    • KRIT1 association with the integrin-binding protein ICAP-1: A new direction in the elucidation of cerebral cavernous malformations (CCM1) pathogenesis
    • Zawistowski JS, Serebriiskii IG, Lee MF, Golemis EA, Marchuk DA: KRIT1 association with the integrin-binding protein ICAP-1: A new direction in the elucidation of cerebral cavernous malformations (CCM1) pathogenesis. Hum Mol Genet 11:389-396, 2002.
    • (2002) Hum Mol Genet , vol.11 , pp. 389-396
    • Zawistowski, J.S.1    Serebriiskii, I.G.2    Lee, M.F.3    Golemis, E.A.4    Marchuk, D.A.5
  • 29
    • 0035542933 scopus 로고    scopus 로고
    • Interacfion between krit1 and icap1α infers perturbation of integrin β1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation
    • Zhang J, Clatterbuck RE, Rigamonti D, Chang DD, Dietz HC: Interacfion between krit1 and icap1α infers perturbation of integrin β1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation. Hum Mol Genet 10:2953-2960, 2001.
    • (2001) Hum Mol Genet , vol.10 , pp. 2953-2960
    • Zhang, J.1    Clatterbuck, R.E.2    Rigamonti, D.3    Chang, D.D.4    Dietz, H.C.5
  • 30
    • 0034061825 scopus 로고    scopus 로고
    • Mutations in KRIT 1 in familial cerebral cavernous malformations
    • Zhang J, Clatterbuck RE, Rigamonti D, Dietz HC: Mutations in KRIT1 in familial cerebral cavernous malformations. Neurosurgery 46:1272-1279, 2000.
    • (2000) Neurosurgery , vol.46 , pp. 1272-1279
    • Zhang, J.1    Clatterbuck, R.E.2    Rigamonti, D.3    Dietz, H.C.4
  • 31


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.