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Volumn 42, Issue 10, 2010, Pages 1661-1671

Cell homeostasis in a Leishmania major mutant overexpressing the spliced leader RNA is maintained by an increased proteolytic activity

Author keywords

Gene expression control; Leishmania; Miniexon; SL RNA; Virulence

Indexed keywords

CELL PROTEIN; CYSTEINE PROTEINASE; SPLICED LEADER RNA; UBIQUITIN;

EID: 77956188750     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2010.06.013     Document Type: Article
Times cited : (4)

References (74)
  • 1
    • 0025339650 scopus 로고
    • Trans splicing of nuclear pre-mRNAs
    • Agabian N. Trans splicing of nuclear pre-mRNAs. Cell 1990, 61:1157-1160.
    • (1990) Cell , vol.61 , pp. 1157-1160
    • Agabian, N.1
  • 4
    • 11844301625 scopus 로고    scopus 로고
    • Leishmania amazonensis: early proteinase activities during promastigote-amastigote differentiation in vitro
    • Alves C.R., Corte-Real S., Bourguignon S.C., Chaves C.S., Saraiva E.M. Leishmania amazonensis: early proteinase activities during promastigote-amastigote differentiation in vitro. Exp Parasitol 2005, 109:38-48.
    • (2005) Exp Parasitol , vol.109 , pp. 38-48
    • Alves, C.R.1    Corte-Real, S.2    Bourguignon, S.C.3    Chaves, C.S.4    Saraiva, E.M.5
  • 5
    • 0034653315 scopus 로고    scopus 로고
    • Overexpression of miniexon gene decreases virulence of Leishmania major in BALB/c mice in vivo
    • Antoniazi S., Lima H.C., Cruz A.K. Overexpression of miniexon gene decreases virulence of Leishmania major in BALB/c mice in vivo. Mol Biochem Parasitol 2000, 107:57-69.
    • (2000) Mol Biochem Parasitol , vol.107 , pp. 57-69
    • Antoniazi, S.1    Lima, H.C.2    Cruz, A.K.3
  • 6
  • 8
    • 33744965065 scopus 로고    scopus 로고
    • Endosome sorting and autophagy are essential for differentiation and virulence of Leishmania major
    • Besteiro S., Williams R.A., Morrison L.S., Coombs G.H., Mottram J.C. Endosome sorting and autophagy are essential for differentiation and virulence of Leishmania major. J Biol Chem 2006, 281:11384-11396.
    • (2006) J Biol Chem , vol.281 , pp. 11384-11396
    • Besteiro, S.1    Williams, R.A.2    Morrison, L.S.3    Coombs, G.H.4    Mottram, J.C.5
  • 9
    • 0028233372 scopus 로고
    • Purification and characterization of a novel species of ubiquitin-carrier protein, E2, that is involved in degradation of non-" N-end rule" protein substrates
    • Blumenfeld N., Gonen H., Mayer A., Smith C.E., Siegel N.R., Schwartz A.L., et al. Purification and characterization of a novel species of ubiquitin-carrier protein, E2, that is involved in degradation of non-" N-end rule" protein substrates. J Biol Chem 1994, 269:9574-9581.
    • (1994) J Biol Chem , vol.269 , pp. 9574-9581
    • Blumenfeld, N.1    Gonen, H.2    Mayer, A.3    Smith, C.E.4    Siegel, N.R.5    Schwartz, A.L.6
  • 10
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 11
    • 33646127577 scopus 로고    scopus 로고
    • Molecular chaperones and protein quality control
    • Bukau B., Weissman J., Horwich A. Molecular chaperones and protein quality control. Cell 2006, 125:443-451.
    • (2006) Cell , vol.125 , pp. 443-451
    • Bukau, B.1    Weissman, J.2    Horwich, A.3
  • 12
    • 0034141646 scopus 로고    scopus 로고
    • Transcription of the kinetoplastid spliced leader RNA gene
    • Campbell D.A., Sturm N.R., Yu M.C. Transcription of the kinetoplastid spliced leader RNA gene. Parasitol Today 2000, 16:78-82.
    • (2000) Parasitol Today , vol.16 , pp. 78-82
    • Campbell, D.A.1    Sturm, N.R.2    Yu, M.C.3
  • 13
    • 0242402131 scopus 로고    scopus 로고
    • Transcription in kinetoplastid protozoa: why be normal?
    • Campbell D.A., Thomas S., Sturm N.R. Transcription in kinetoplastid protozoa: why be normal?. Microbes Infect 2003, 5:1231-1240.
    • (2003) Microbes Infect , vol.5 , pp. 1231-1240
    • Campbell, D.A.1    Thomas, S.2    Sturm, N.R.3
  • 14
    • 57449113835 scopus 로고    scopus 로고
    • Turnover of oxidatively modified proteins: the usage of in vitro and metabolic labeling
    • Catalgol B., Grune T. Turnover of oxidatively modified proteins: the usage of in vitro and metabolic labeling. Free Radic Biol Med 2009, 46:8-13.
    • (2009) Free Radic Biol Med , vol.46 , pp. 8-13
    • Catalgol, B.1    Grune, T.2
  • 16
    • 0037422598 scopus 로고    scopus 로고
    • RNA polymerase II-dependent transcription in trypanosomes is associated with a SNAP complex-like transcription facto
    • Das A., Bellofatto V. RNA polymerase II-dependent transcription in trypanosomes is associated with a SNAP complex-like transcription facto. Proc Natl Acad Sci USA 2003, 100:80-85.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 80-85
    • Das, A.1    Bellofatto, V.2
  • 18
    • 3042555141 scopus 로고    scopus 로고
    • Leishmaniasis: current situation and new perspectives
    • Desjeux P. Leishmaniasis: current situation and new perspectives. Comp Immunol Microbiol Infect Dis 2004, 27:305-318.
    • (2004) Comp Immunol Microbiol Infect Dis , vol.27 , pp. 305-318
    • Desjeux, P.1
  • 19
    • 18944380422 scopus 로고    scopus 로고
    • Actively transcribing RNA polymerase II concentrates on spliced leader genes in the nucleus of Trypanosoma cruzi
    • Dossin F.M., Schenkman S. Actively transcribing RNA polymerase II concentrates on spliced leader genes in the nucleus of Trypanosoma cruzi. Eukaryot Cell 2005, 4:960-970.
    • (2005) Eukaryot Cell , vol.4 , pp. 960-970
    • Dossin, F.M.1    Schenkman, S.2
  • 20
    • 0031978181 scopus 로고    scopus 로고
    • Base-calling of automated sequencer traces using PHRED. II. Error probabilities
    • Ewing B., Green P. Base-calling of automated sequencer traces using PHRED. II. Error probabilities. Genome Res 1998, 8:186-194.
    • (1998) Genome Res , vol.8 , pp. 186-194
    • Ewing, B.1    Green, P.2
  • 22
    • 0021672206 scopus 로고
    • L-Pyroglutamyl-l-phenylalanyl-l-leucine-p-nitroanilide-a chromogenic substrate for thiol proteinase assay
    • Filippova I., Lysogorskaya E.N., Oksenoit E.S., Rudenskaya G.N., Stepanov V.M. l-Pyroglutamyl-l-phenylalanyl-l-leucine-p-nitroanilide-a chromogenic substrate for thiol proteinase assay. Anal Biochem 1984, 143:293-297.
    • (1984) Anal Biochem , vol.143 , pp. 293-297
    • Filippova, I.1    Lysogorskaya, E.N.2    Oksenoit, E.S.3    Rudenskaya, G.N.4    Stepanov, V.M.5
  • 23
    • 0035012676 scopus 로고    scopus 로고
    • Secretory and endocytic pathways converge in a dynamic endosomal system in a primitive protozoan
    • Ghedin E., Debrabant A., Engel J.C., Dwyer D.M. Secretory and endocytic pathways converge in a dynamic endosomal system in a primitive protozoan. Traffic 2001, 2:175-188.
    • (2001) Traffic , vol.2 , pp. 175-188
    • Ghedin, E.1    Debrabant, A.2    Engel, J.C.3    Dwyer, D.M.4
  • 24
    • 0030905981 scopus 로고    scopus 로고
    • New insights into the mechanisms and importance of the proteasome in intracellular protein degradation
    • Goldberg A.L., Akopian T.N., Kisselev A.F., Lee D.H., Rohrwild M. New insights into the mechanisms and importance of the proteasome in intracellular protein degradation. Biol Chem 1997, 378:131-140.
    • (1997) Biol Chem , vol.378 , pp. 131-140
    • Goldberg, A.L.1    Akopian, T.N.2    Kisselev, A.F.3    Lee, D.H.4    Rohrwild, M.5
  • 25
    • 77649219141 scopus 로고    scopus 로고
    • Persistent ER stress induces the spliced leader RNA silencing pathway (SLS), leading to programmed cell death in Trypanosoma brucei
    • Goldshmidt H., Matas D., Kabi A., Carmi S., Hope R., Michaeli S. Persistent ER stress induces the spliced leader RNA silencing pathway (SLS), leading to programmed cell death in Trypanosoma brucei. PLoS Pathog 2010, 6:e1000731.
    • (2010) PLoS Pathog , vol.6
    • Goldshmidt, H.1    Matas, D.2    Kabi, A.3    Carmi, S.4    Hope, R.5    Michaeli, S.6
  • 26
    • 0030939757 scopus 로고    scopus 로고
    • Leishmania vaccines: old and new
    • Handman E. Leishmania vaccines: old and new. Parasitol Today 1997, 13:236-238.
    • (1997) Parasitol Today , vol.13 , pp. 236-238
    • Handman, E.1
  • 27
    • 0035067363 scopus 로고    scopus 로고
    • Leishmaniasis: current status of vaccine development
    • Handman E. Leishmaniasis: current status of vaccine development. Clin Microbiol Rev 2001, 14:229-243.
    • (2001) Clin Microbiol Rev , vol.14 , pp. 229-243
    • Handman, E.1
  • 28
    • 0033517487 scopus 로고    scopus 로고
    • Leishmaniasis
    • Herwaldt B. Leishmaniasis. Lancet 1999, 1191-1199.
    • (1999) Lancet , pp. 1191-1199
    • Herwaldt, B.1
  • 29
    • 34250026943 scopus 로고    scopus 로고
    • The promoter and transcribed regions of the Leishmania tarentolae spliced leader RNA gene array are devoid of nucleosomes
    • Hitchcock R.A., Thomas S., Campbell D.A., Sturm N.R. The promoter and transcribed regions of the Leishmania tarentolae spliced leader RNA gene array are devoid of nucleosomes. BMC Microbiol 2007, 7:44.
    • (2007) BMC Microbiol , vol.7 , pp. 44
    • Hitchcock, R.A.1    Thomas, S.2    Campbell, D.A.3    Sturm, N.R.4
  • 31
    • 0033169025 scopus 로고    scopus 로고
    • Glycosylphosphatidylinositol biosynthetic enzymes are localized to a stable tubular subcompartment of the endoplasmic reticulum in Leishmania mexicana
    • Ilgoutz S.C., Mullin K.A., Southwell B.R., McConville M.J. Glycosylphosphatidylinositol biosynthetic enzymes are localized to a stable tubular subcompartment of the endoplasmic reticulum in Leishmania mexicana. EMBO J 1999, 18:3643-3654.
    • (1999) EMBO J , vol.18 , pp. 3643-3654
    • Ilgoutz, S.C.1    Mullin, K.A.2    Southwell, B.R.3    McConville, M.J.4
  • 32
    • 0024554055 scopus 로고
    • Structural alterations of chromosome 2 in Leishmania major as evidence for diploidy, including spontaneous amplification of the mini-exon array
    • Iovannisci D.M., Beverley S.M. Structural alterations of chromosome 2 in Leishmania major as evidence for diploidy, including spontaneous amplification of the mini-exon array. Mol Biochem Parasitol 1989, 34:177-188.
    • (1989) Mol Biochem Parasitol , vol.34 , pp. 177-188
    • Iovannisci, D.M.1    Beverley, S.M.2
  • 33
    • 0025122367 scopus 로고
    • Stable transfection of the human parasite Leishmania major delineates a 30-kilobase region sufficient for extrachromosomal replication and expression
    • Kapler G.M., Coburn C.M., Beverley S.M. Stable transfection of the human parasite Leishmania major delineates a 30-kilobase region sufficient for extrachromosomal replication and expression. Mol Cell Biol 1990, 10:1084-1094.
    • (1990) Mol Cell Biol , vol.10 , pp. 1084-1094
    • Kapler, G.M.1    Coburn, C.M.2    Beverley, S.M.3
  • 34
    • 55049098755 scopus 로고    scopus 로고
    • Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2(alpha) phosphorylation at Thr169
    • Kramer S., Queiroz R., Ellis L., Webb H., Hoheisel J.D., Clayton C., et al. Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2(alpha) phosphorylation at Thr169. J Cell Sci 2008, 121:3002-3014.
    • (2008) J Cell Sci , vol.121 , pp. 3002-3014
    • Kramer, S.1    Queiroz, R.2    Ellis, L.3    Webb, H.4    Hoheisel, J.D.5    Clayton, C.6
  • 35
    • 33750735379 scopus 로고    scopus 로고
    • The major surface-metalloprotease of the parasitic protozoan, Leishmania, protects against antimicrobial peptide-induced apoptotic killing
    • Kulkarni M.M., McMaster W.R., Kamysz E., Kamysz W., Engman D.M., McGwire B.S. The major surface-metalloprotease of the parasitic protozoan, Leishmania, protects against antimicrobial peptide-induced apoptotic killing. Mol Microbiol 2006, 62:1484-1497.
    • (2006) Mol Microbiol , vol.62 , pp. 1484-1497
    • Kulkarni, M.M.1    McMaster, W.R.2    Kamysz, E.3    Kamysz, W.4    Engman, D.M.5    McGwire, B.S.6
  • 36
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 37
    • 0033525731 scopus 로고    scopus 로고
    • Developmental regulation of spliced leader RNA gene in Leishmania donovani amastigotes is mediated by specific polyadenylation
    • Lamontagne J., Papadopoulou B. Developmental regulation of spliced leader RNA gene in Leishmania donovani amastigotes is mediated by specific polyadenylation. J Biol Chem 1999, 274:6602-6609.
    • (1999) J Biol Chem , vol.274 , pp. 6602-6609
    • Lamontagne, J.1    Papadopoulou, B.2
  • 38
    • 33846202033 scopus 로고    scopus 로고
    • Genomic and proteomic expression analysis of Leishmania promastigote and amastigote life stages: the Leishmania genome is constitutively expressed
    • Leifso K., Cohen-Freue G., Dogra N., Murray A., McMaster W.R. Genomic and proteomic expression analysis of Leishmania promastigote and amastigote life stages: the Leishmania genome is constitutively expressed. Mol Biochem Parasitol 2007, 152:35-46.
    • (2007) Mol Biochem Parasitol , vol.152 , pp. 35-46
    • Leifso, K.1    Cohen-Freue, G.2    Dogra, N.3    Murray, A.4    McMaster, W.R.5
  • 39
    • 4344675436 scopus 로고    scopus 로고
    • Chemical synthesis and binding activity of the trypanosomatid cap-4 structure
    • Lewdorowicz M., Yoffe Y., Zuberek J., Jemielity J., Stepinski J., Kierzek R., et al. Chemical synthesis and binding activity of the trypanosomatid cap-4 structure. RNA 2004, 10:1469-1478.
    • (2004) RNA , vol.10 , pp. 1469-1478
    • Lewdorowicz, M.1    Yoffe, Y.2    Zuberek, J.3    Jemielity, J.4    Stepinski, J.5    Kierzek, R.6
  • 40
    • 0034743629 scopus 로고    scopus 로고
    • The 3'-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo
    • Li Y., Chen Z.Y., Wang W., Baker C.C., Krug R.M. The 3'-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo. RNA 2001, 7:920-931.
    • (2001) RNA , vol.7 , pp. 920-931
    • Li, Y.1    Chen, Z.Y.2    Wang, W.3    Baker, C.C.4    Krug, R.M.5
  • 41
    • 0026674886 scopus 로고
    • Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction
    • Liang P., Pardee A.B. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 1992, 257:967-971.
    • (1992) Science , vol.257 , pp. 967-971
    • Liang, P.1    Pardee, A.B.2
  • 42
    • 40649089936 scopus 로고    scopus 로고
    • Differential display of mRNA by PCR. Curr Protoc Mol Biol; Chapter 25, Unit
    • Liang P, Pardee AB. Differential display of mRNA by PCR. Curr Protoc Mol Biol; 2001, Chapter 25, Unit 25B 23.
    • (2001) , vol.23 , Issue.25 B
    • Liang, P.1    Pardee, A.B.2
  • 43
    • 70350004186 scopus 로고    scopus 로고
    • Dissimilar peptidase production by avirulent and virulent promastigotes of Leishmania braziliensis: inference on the parasite proliferation and interaction with macrophages
    • Lima A.K., Elias C.G., Souza J.E., Santos A.L., Dutra P.M. Dissimilar peptidase production by avirulent and virulent promastigotes of Leishmania braziliensis: inference on the parasite proliferation and interaction with macrophages. Parasitology 2009, 136:1179-1191.
    • (2009) Parasitology , vol.136 , pp. 1179-1191
    • Lima, A.K.1    Elias, C.G.2    Souza, J.E.3    Santos, A.L.4    Dutra, P.M.5
  • 44
    • 34047155622 scopus 로고    scopus 로고
    • Spliced-leader RNA silencing: a novel stress-induced mechanism in Trypanosoma brucei
    • Lustig Y., Sheiner L., Vagima Y., Goldshmidt H., Das A., Bellofatto V., et al. Spliced-leader RNA silencing: a novel stress-induced mechanism in Trypanosoma brucei. EMBO Rep 2007, 8:408-413.
    • (2007) EMBO Rep , vol.8 , pp. 408-413
    • Lustig, Y.1    Sheiner, L.2    Vagima, Y.3    Goldshmidt, H.4    Das, A.5    Bellofatto, V.6
  • 47
    • 27444434267 scopus 로고    scopus 로고
    • Distinct 3'-untranslated region elements regulate stage-specific mRNA accumulation and translation in Leishmania
    • McNicoll F., Muller M., Cloutier S., Boilard N., Rochette A., Dube M., et al. Distinct 3'-untranslated region elements regulate stage-specific mRNA accumulation and translation in Leishmania. J Biol Chem 2005, 280:35238-35246.
    • (2005) J Biol Chem , vol.280 , pp. 35238-35246
    • McNicoll, F.1    Muller, M.2    Cloutier, S.3    Boilard, N.4    Rochette, A.5    Dube, M.6
  • 48
    • 70849122402 scopus 로고    scopus 로고
    • Recombinant Leishmania tarentolae expressing the A2 virulence gene as a novel candidate vaccine against visceral leishmaniasis
    • Mizbani A., Taheri T., Zahedifard F., Taslimi Y., Azizi H., Azadmanesh K., et al. Recombinant Leishmania tarentolae expressing the A2 virulence gene as a novel candidate vaccine against visceral leishmaniasis. Vaccine 2009, 28:53-62.
    • (2009) Vaccine , vol.28 , pp. 53-62
    • Mizbani, A.1    Taheri, T.2    Zahedifard, F.3    Taslimi, Y.4    Azizi, H.5    Azadmanesh, K.6
  • 49
    • 0035168055 scopus 로고    scopus 로고
    • Regulated degradation of an endoplasmic reticulum membrane protein in a tubular lysosome in Leishmania mexicana
    • Mullin K.A., Foth B.J., Ilgoutz S.C., Callaghan J.M., Zawadzki J.L., McFadden G.I., et al. Regulated degradation of an endoplasmic reticulum membrane protein in a tubular lysosome in Leishmania mexicana. Mol Biol Cell 2001, 12:2364-2377.
    • (2001) Mol Biol Cell , vol.12 , pp. 2364-2377
    • Mullin, K.A.1    Foth, B.J.2    Ilgoutz, S.C.3    Callaghan, J.M.4    Zawadzki, J.L.5    McFadden, G.I.6
  • 50
    • 38049129044 scopus 로고    scopus 로고
    • The Leishmania-macrophage interaction: a metabolic perspective
    • Naderer T., McConville M.J. The Leishmania-macrophage interaction: a metabolic perspective. Cell Microbiol 2008, 10:301-308.
    • (2008) Cell Microbiol , vol.10 , pp. 301-308
    • Naderer, T.1    McConville, M.J.2
  • 51
    • 34447125198 scopus 로고    scopus 로고
    • The poly(A)-dependent transcriptional pause is mediated by CPSF acting on the body of the polymerase
    • Nag A., Narsinh K., Martinson H.G. The poly(A)-dependent transcriptional pause is mediated by CPSF acting on the body of the polymerase. Nat Struct Mol Biol 2007, 14:662-669.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 662-669
    • Nag, A.1    Narsinh, K.2    Martinson, H.G.3
  • 52
    • 0023931883 scopus 로고
    • Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G-250 and R-250
    • Neuhoff V., Arold N., Taube D., Ehrhardt W. Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G-250 and R-250. Electrophoresis 1988, 9:255-262.
    • (1988) Electrophoresis , vol.9 , pp. 255-262
    • Neuhoff, V.1    Arold, N.2    Taube, D.3    Ehrhardt, W.4
  • 54
    • 53749088914 scopus 로고    scopus 로고
    • Persistent parasites and immunologic memory in cutaneous leishmaniasis: implications for vaccine designs and vaccination strategies
    • Okwor I., Uzonna J. Persistent parasites and immunologic memory in cutaneous leishmaniasis: implications for vaccine designs and vaccination strategies. Immunol Res 2008, 41:123-136.
    • (2008) Immunol Res , vol.41 , pp. 123-136
    • Okwor, I.1    Uzonna, J.2
  • 55
    • 0032821504 scopus 로고    scopus 로고
    • The Leishmania mexicana proteasome
    • Robertson C.D. The Leishmania mexicana proteasome. Mol Biochem Parasitol 1999, 103:49-60.
    • (1999) Mol Biochem Parasitol , vol.103 , pp. 49-60
    • Robertson, C.D.1
  • 56
    • 47249134311 scopus 로고    scopus 로고
    • Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species
    • Rochette A., Raymond F., Ubeda J.M., Smith M., Messier N., Boisvert S., et al. Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species. BMC Genomics 2008, 9:255.
    • (2008) BMC Genomics , vol.9 , pp. 255
    • Rochette, A.1    Raymond, F.2    Ubeda, J.M.3    Smith, M.4    Messier, N.5    Boisvert, S.6
  • 57
    • 35348965640 scopus 로고    scopus 로고
    • Evidence for a capping enzyme with specificity for the trypanosome spliced leader RNA
    • Ruan J.P., Shen S., Ullu E., Tschudi C. Evidence for a capping enzyme with specificity for the trypanosome spliced leader RNA. Mol Biochem Parasitol 2007, 156:246-254.
    • (2007) Mol Biochem Parasitol , vol.156 , pp. 246-254
    • Ruan, J.P.1    Shen, S.2    Ullu, E.3    Tschudi, C.4
  • 58
    • 0027182679 scopus 로고
    • Shuttle cosmid vectors for the trypanosomatid parasite Leishmania
    • Ryan K.A., Dasgupta S., Beverley S.M. Shuttle cosmid vectors for the trypanosomatid parasite Leishmania. Gene 1993, 131:145-150.
    • (1993) Gene , vol.131 , pp. 145-150
    • Ryan, K.A.1    Dasgupta, S.2    Beverley, S.M.3
  • 59
    • 0037029138 scopus 로고    scopus 로고
    • Elongation factor-2 kinase and its newly discovered relatives
    • Ryazanov A.G. Elongation factor-2 kinase and its newly discovered relatives. FEBS Lett 2002, 514:26-29.
    • (2002) FEBS Lett , vol.514 , pp. 26-29
    • Ryazanov, A.G.1
  • 60
    • 0027967462 scopus 로고
    • A conserved upstream element is essential for transcription of the Leishmania tarentolae mini-exon gene
    • Saito R.M., Elgort M.G., Campbell D.A. A conserved upstream element is essential for transcription of the Leishmania tarentolae mini-exon gene. EMBO J 1994, 13:5460-5469.
    • (1994) EMBO J , vol.13 , pp. 5460-5469
    • Saito, R.M.1    Elgort, M.G.2    Campbell, D.A.3
  • 61
    • 77956190073 scopus 로고
    • Molecular cloning: a laboratory manual, Editor ed. Cold Spring Harbor Laboratory Press
    • Sambrook J, Fritsch EF, Maniatis T. Molecular cloning: a laboratory manual, Editor ed. Cold Spring Harbor Laboratory Press, 1989.
    • (1989)
    • Sambrook, J.1    Fritsch, E.F.2    Maniatis, T.3
  • 62
    • 33646171699 scopus 로고    scopus 로고
    • Divergent roles of IRE1alpha and PERK in the unfolded protein response
    • Schroder M., Kaufman R.J. Divergent roles of IRE1alpha and PERK in the unfolded protein response. Curr Mol Med 2006, 6:5-36.
    • (2006) Curr Mol Med , vol.6 , pp. 5-36
    • Schroder, M.1    Kaufman, R.J.2
  • 64
    • 3242719785 scopus 로고    scopus 로고
    • The Leishmania chagasi proteasome: role in promastigotes growth and amastigotes survival within murine macrophages
    • Silva-Jardim I., Horta M.F., Ramalho-Pinto F.J. The Leishmania chagasi proteasome: role in promastigotes growth and amastigotes survival within murine macrophages. Acta Trop 2004, 91:121-130.
    • (2004) Acta Trop , vol.91 , pp. 121-130
    • Silva-Jardim, I.1    Horta, M.F.2    Ramalho-Pinto, F.J.3
  • 65
    • 0033516650 scopus 로고    scopus 로고
    • The role of intron structures in trans-splicing and cap 4 formation for the Leishmania spliced leader RNA
    • Sturm N.R., Campbell D.A. The role of intron structures in trans-splicing and cap 4 formation for the Leishmania spliced leader RNA. J Biol Chem 1999, 274:19361-19367.
    • (1999) J Biol Chem , vol.274 , pp. 19361-19367
    • Sturm, N.R.1    Campbell, D.A.2
  • 66
    • 14444278049 scopus 로고    scopus 로고
    • Efficient trans-splicing of mutated spliced leader exons in Leishmania tarentolae
    • Sturm N.R., Fleischmann J., Campbell D.A. Efficient trans-splicing of mutated spliced leader exons in Leishmania tarentolae. J Biol Chem 1998, 273:18689-18692.
    • (1998) J Biol Chem , vol.273 , pp. 18689-18692
    • Sturm, N.R.1    Fleischmann, J.2    Campbell, D.A.3
  • 67
    • 0032951485 scopus 로고    scopus 로고
    • Transcription termination and 3'-end processing of the spliced leader RNA in kinetoplastids
    • Sturm N.R., Yu M.C., Campbell D.A. Transcription termination and 3'-end processing of the spliced leader RNA in kinetoplastids. Mol Cell Biol 1999, 19:1595-1604.
    • (1999) Mol Cell Biol , vol.19 , pp. 1595-1604
    • Sturm, N.R.1    Yu, M.C.2    Campbell, D.A.3
  • 69
    • 0037133234 scopus 로고    scopus 로고
    • Novel interactions of Saccharomyces cerevisiae type 1 protein phosphatase identified by single-step affinity purification and mass spectrometry
    • Walsh E.P., Lamont D.J., Beattie K.A., Stark M.J. Novel interactions of Saccharomyces cerevisiae type 1 protein phosphatase identified by single-step affinity purification and mass spectrometry. Biochemistry 2002, 41:2409-2420.
    • (2002) Biochemistry , vol.41 , pp. 2409-2420
    • Walsh, E.P.1    Lamont, D.J.2    Beattie, K.A.3    Stark, M.J.4
  • 70
    • 33748300634 scopus 로고    scopus 로고
    • Cysteine peptidases CPA and CPB are vital for autophagy and differentiation in Leishmania mexicana
    • Williams R.A., Tetley L., Mottram J.C., Coombs G.H. Cysteine peptidases CPA and CPB are vital for autophagy and differentiation in Leishmania mexicana. Mol Microbiol 2006, 61:655-674.
    • (2006) Mol Microbiol , vol.61 , pp. 655-674
    • Williams, R.A.1    Tetley, L.2    Mottram, J.C.3    Coombs, G.H.4
  • 71
    • 73449146016 scopus 로고    scopus 로고
    • Major surface protease of trypanosomatids: one size fits all?
    • Yao C. Major surface protease of trypanosomatids: one size fits all?. Infect Immun 2010, 78:22-31.
    • (2010) Infect Immun , vol.78 , pp. 22-31
    • Yao, C.1
  • 72
    • 8544262185 scopus 로고    scopus 로고
    • In vivo selection for Leishmania donovani miniexon genes that increase virulence in Leishmania major
    • Zhang W.W., Matlashewski G. In vivo selection for Leishmania donovani miniexon genes that increase virulence in Leishmania major. Mol Microbiol 2004, 54:1051-1062.
    • (2004) Mol Microbiol , vol.54 , pp. 1051-1062
    • Zhang, W.W.1    Matlashewski, G.2
  • 73
    • 33646354916 scopus 로고    scopus 로고
    • Hsp70 chaperone machine remodels protein aggregates at the initial step of Hsp70-Hsp100-dependent disaggregation
    • Zietkiewicz S., Lewandowska A., Stocki P., Liberek K. Hsp70 chaperone machine remodels protein aggregates at the initial step of Hsp70-Hsp100-dependent disaggregation. J Biol Chem 2006, 281:7022-7029.
    • (2006) J Biol Chem , vol.281 , pp. 7022-7029
    • Zietkiewicz, S.1    Lewandowska, A.2    Stocki, P.3    Liberek, K.4
  • 74
    • 0028061958 scopus 로고
    • The role of pH and temperature in the development of Leishmania parasites
    • Zilberstein D., Shapira M. The role of pH and temperature in the development of Leishmania parasites. Annu Rev Microbiol 1994, 48:449-470.
    • (1994) Annu Rev Microbiol , vol.48 , pp. 449-470
    • Zilberstein, D.1    Shapira, M.2


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