Enhancement of hydrophilic drug loading and release characteristics through micellization with new carboxymethyldextran-PEG block copolymers of tunable charge density

International Journal of Pharmaceutics

Volumn 356, Issue 1-2, 2008, Pages 248-258

  Soliman, Ghareb Mohamed ^a   Winnik, Françoise M ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Dextran; Diminazene diaceturate; Electrostatic interactions; Hydrophilic drug; Polyelectrolytes; Polyion complex micelles

Indexed keywords

CARBOXYMETHYLDEXTRAN; COPOLYMER; MACROGOL; SODIUM CHLORIDE; TREHALOSE;

ARTICLE; DENSITY; FREEZE DRYING; HYDRODYNAMICS; HYDROPHILICITY; IN VITRO STUDY; IN VIVO STUDY; MICELLE; MICELLIZATION; MOLECULAR WEIGHT; PH MEASUREMENT; PRIORITY JOURNAL; SALINITY;

CHEMISTRY, PHARMACEUTICAL; DEXTRANS; DIMINAZENE; DRUG CARRIERS; DRUG STABILITY; DRUG STORAGE; FREEZE DRYING; HYDROGEN-ION CONCENTRATION; MICELLES; POLYETHYLENE GLYCOLS; POLYMERS; SALINITY; SODIUM CHLORIDE; TREHALOSE;

EID: 43049102385     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.12.029     Document Type: Article

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