Overlaps between autism and language impairment: Phenomimicry or shared etiology?

Behavior Genetics

Volumn 40, Issue 5, 2010, Pages 618-629

  Bishop, D V M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Autism; Comorbidity; Epistasis; Specific language impairment

Indexed keywords

ARTICLE; AUTISM; COMORBIDITY; CONTROLLED STUDY; GENETIC EPISTASIS; GENOTYPE ENVIRONMENT INTERACTION; LANGUAGE DISABILITY; MOLECULAR GENETICS; PLEIOTROPY; RELATIVE; RISK FACTOR;

AUTISTIC DISORDER; COMORBIDITY; EPISTASIS, GENETIC; HUMANS; LANGUAGE DISORDERS; MODELS, THEORETICAL; SOFTWARE;

EID: 77956181575     PISSN: 00018244     EISSN: 15733297     Source Type: Journal    
DOI: 10.1007/s10519-010-9381-x     Document Type: Article

References (54)

1. M Alarcón BS Abrahams JL Stone JA Duvall JV Perederiy JM Bomar J Sebat M Wigler CL Martin DH Ledbetter SF Nelson RM Cantor DH Geschwind 2008 Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene Am J Hum Genet 82 1 150 159 10.1016/j.ajhg.2007.09. 005 18179893
2. American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Association, Washington, DC
3. DE Arking DJ Cutler CW Brune TM Teslovich K West M Ikeda A Rea M Guy S Lin EH Cook A Chakravarti 2008 A common genetic variant in the neurexin superfamily member CNTNAP2 increases familial risk of autism Am J Hum Genet 82 1 160 164 10.1016/j.ajhg.2007.09.015 18179894
4. A Bailey A Le Couteur I Gottestman P Bolton E Simonoff E Yuzda M Rutter 1995 Autism as a strongly genetic disorder: evidence from a British twin study Psychol Med 25 63 77 10.1017/S0033291700028099 7792363
5. A Bailey S Palferman L Heavey A Le Couteur 1998 Autism: the phenotype in relatives J Autism Dev Disord 28 369 392 10.1023/A:1026048320785 9813774
6. G Baird E Simonoff A Pickles S Chandler T Loucas D Meldrum T Charman 2006 Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP) Lancet 368 9531 210 215 10.1016/S0140-6736(06)69041-7 16844490
7. JG Barry I Yasin DVM Bishop 2007 Heritable risk factors associated with language impairments Genes Brain Behav 6 66 76 10.1111/j.1601-183X.2006.00232.x 17233642
8. L Bartak M Rutter A Cox 1975 A comparative study of infantile autism and specific developmental receptive language disorder: I. The children Br J Psychiatry 126 127 145 10.1192/bjp.126.2.127 1131465
9. BR Bill DH Geschwind 2009 Genetic advances in autism: heterogeneity and convergence on shared pathways Curr Opin Genet Dev 19 271 278 10.1016/j.gde.2009.04.004 19477629
10. Bishop DVM (2000) Pragmatic language impairment: a correlate of SLI, a distinct subgroup, or part of the autistic continuum? In: Bishop DVM, Leonard LB (eds) Speech and language impairments in children: causes, characteristics, intervention and outcome. Psychology Press, Hove, UK, pp 99-113
11. Bishop DVM (2003) Autism and specific language impairment: categorical distinction or continuum? In: Bock G, Goode J (eds) Autism: neural basis and treatment possibilities Novartis Foundation Symposium 251. John Wiley, Chichester, pp 213-226
12. DVM Bishop 2005 DeFries-Fulker analysis of twin data with skewed distributions: cautions and recommendations from a study of children's use of verb inflections Behav Genet 35 479 490 10.1007/s10519-004-1834-7 15971028
13. DVM Bishop 2006 What causes specific language impairment in children? Curr Dir Psychol Sci 15 217 221 10.1111/j.1467-8721.2006.00439.x 19009045
14. DVM Bishop 2009 Genes, cognition and communication: insights from neurodevelopmental disorders Year Cognitive Neurosci: Ann NY Acad Sci 1156 1 18 10.1111/j.1749-6632.2009.04419.x
15. DVM Bishop ME Hayiou-Thomas 2008 Heritability of specific language impairment depends on diagnostic criteria Genes Brain Behav 7 365 372 10.1111/j.1601-183X.2007.00360.x 17919296
16. Bishop DVM, Norbury CF (2008) Speech and language disorders. In: Rutter M, Bishop DVM, Pine D, Scott S, Stevenson J, Taylor E, Thapar A (eds) Rutter's child and adolescent psychiatry. Blackwell, Oxford, pp 782-801
17. DVM Bishop T North C Donlan 1995 Genetic basis of specific language impairment: evidence from a twin study Dev Med Child Neurol 37 56 71 10.1111/j.1469-8749.1995.tb11932.x 7828787
18. DVM Bishop T North C Donlan 1996 Nonword repetition as a behavioural marker for inherited language impairment: evidence from a twin study J Child Psychol Psychiatry 37 391 403 10.1111/j.1469-7610.1996.tb01420.x 8735439
19. DVM Bishop M Maybery D Wong A Maley W Hill J Hallmayer 2004 Are phonological processing deficits part of the broad autism phenotype? Am J Med Genet 128B 54 60 10.1002/ajmg.b.30039 15211632
20. D Cantwell L Baker M Rutter 1978 A comparative study of infantile autism and specific developmental language disorder. IV. Analysis of syntax and language function J Child Psychol Psychiatry 19 351 362 10.1111/j.1469-7610. 1978.tb00481.x 711824
21. O Carlborg CS Haley 2004 Epistasis: too often neglected in complex trait studies? Nat Rev Genet 5 8 618 625 10.1038/nrg1407 15266344
22. CJ Dover A Le Couteur 2007 How to diagnose autism Arch Dis Child 92 6 540 545 10.1136/adc.2005.086280 17515625
23. DS Falconer 1965 The inheritance of liability to certain diseases, estimated from the incidence among relatives Ann Hum Genet 29 51 71 10.1111/j.1469-1809.1965.tb00500.x
24. SE Fisher 2007 Molecular windows into speech and language disorders Folia Phoniatr Logop 59 3 130 140 10.1159/000101771 17556856
25. S Folstein M Rutter 1977 Infantile autism: a genetic study of 21 twin pairs J Child Psychol Psychiatry 18 297 321 10.1111/j.1469-7610.1977.tb00443.x 562353
26. Gottesman II TD Gould 2003 The endophenotype concept in psychiatry: etymology and strategic intentions Am J Psychiat 160 636 645 10.1176/appi.ajp.160.4.636 12668349
27. J Hallmayer EJ Glasson C Bower B Petterson L Croen J Grether N Risch 2002 On the twin risk in autism Am J Hum Genet 71 941 946 10.1086/342990 12297988
28. MC Keller G Miller 2006 Resolving the paradox of common, harmful, heritable mental disorders: which evolutionary genetic models work best? Beh Brain Sci 29 385 452
29. M King P Bearman 2009 Diagnostic change and the increased prevalence of autism Int J Epidemiol 38 5 1224 1234 10.1093/ije/dyp261 19737791
30. MM Kjelgaard H Tager-Flusberg 2001 An investigation of language impairment in autism: implications for genetic subgroups Lang Cog Proc 16 287 308 10.1080/01690960042000058
31. G Konopka JM Bomar K Winden G Coppola ZO Jonsson F Gao S Peng TM Preuss JA Wohlschlegel DH Geschwind 2009 Human-specific transcriptional regulation of CNS development genes by FOXP2 Nature 462 7270 213 217 10.1038/nature08549 19907493
32. BA Lewis LA Thompson 1992 A study of developmental speech and language disorders in twins J Sp Hear Res 35 1086 1094
33. BA Lewis NJ Cox PJ Byard 1993 Segregation analysis of speech and language disorders Behav Genet 23 291 297 10.1007/BF01082469 8352725
34. KA Lindgren SE Folstein JB Tomblin H Tager-Flusberg 2009 Language and reading abilities of children with autism spectrum disorders and specific language impairment and their first-degree relatives Autism Res 2 1 22 38 10.1002/aur.63 19358305
35. T Loucas T Charman A Pickles E Simonoff S Chandler D Meldrum G Baird 2008 Autistic symptomatology and language ability in autism spectrum disorder and specific language impairment J Child Psychol Psychiatry 49 1184 1192 19017030
36. MC Neale KS Kendler 1995 Models of comorbidity of multifactorial disorders Am J Hum Genet 57 935 953 7573055
37. DF Newbury E Bonora JA Lamb SE Fisher CSL Lai G Baird L Jannoun V Slonims CM Stott MJ Merricks PF Bolton AJ Bailey AP Monaco International Molecular Genetic Study of Autism Consortium 2002 FOXP2 is not a major susceptibility gene for autism or specific language impairment Am J Hum Genet 70 1318 1327 10.1086/339931 11894222
38. CJ Newschaffer D Fallin NL Lee 2002 Heritable and nonheritable risk factors for autism spectrum disorders Epidem Rev 24 137 153 10.1093/epirev/ mxf010
39. A Pickles P Bolton H Macdonald 1995 Latent class analysis of recurrence risks for complex phenotypes with selection and measurement error: a twin and family history study of autism Am J Hum Genet 57 717 726 7668301
40. I Rapin M Dunn 2003 Update on the language disorders of individuals on the autistic spectrum Brain Dev 2003 166 172 10.1016/S0387-7604(02)00191-2
41. N Risch D Spiker L Lotspeich N Nouri D Hinds J Hallmayer L Kalaydjieva P McCague S Dimiceli T Pitts L Nguyen J Yang C Harper D Thorpe S Vermeer H Young J Hebert A Lin J Ferguson C Chiotti S Wiese-Slater T Rogers B Salmon P Nicholas PB Petersen C Pingree W McMahon DL Wong LL Cavalli-Sforza HC Kraemer RM Myers 1999 A genomic screen of autism: evidence for a multilocus etiology Am J Hum Genet 65 2 493 507 10.1086/302497 10417292
42. A Ronald F Happe P Bolton LM Butcher TS Price S Wheelwright S Baron-Cohen R Plomin 2006 Genetic heterogeneity between the three components of the autism spectrum: a twin study J Am Acad Ch Adol Psychiat 45 6 691 699 10.1097/01.chi.0000215325.13058.9d
43. Rutter M (2005a) Genetic influences and autism. In: Volkmar FR, Paul R, Klin A, Cohen D (eds) Handbook of autism and pervasive developmental disorders, 3rd edition edn. John Wiley and Sons, Hoboken, NJ, pp 425-452
44. M Rutter 2005 Incidence of autism spectrum disorders: changes over time and their meaning Acta Paed 94 2 15 10.1080/08035250410023124
45. Sing CF, Reilly SL (1993) Genetics of common diseases that aggregate, but do not segregate in families. In: Sing CF, Hanis CL (eds) Genetics of cellular, individual, family and population variability. Oxford University Press, New York, pp 140-161
46. S Steffenburg C Gillberg L Hellgren L Andersson IC Gillberg G Jakobsson, et al. 1989 A twin study of autism in Denmark, Finland, Iceland, Norway and Sweden J Child Psychol Psychiatry 30 3 405 416 10.1111/j.1469-7610.1989.tb00254. x 2745591
47. HK Tabor NJ Risch RM Myers 2002 Candidate-gene approaches for studying complex genetic traits: practical considerations Nat Rev Genet 3 5 391 397 10.1038/nrg796 11988764
48. H Tager-Flusberg RM Joseph 2003 Identifying neurocognitive phenotypes in autism Philos Trans Roy Soc Lond B 358 303 314 10.1098/rstb.2002.1198
49. JB Tomblin PR Buckwalter 1998 Heritability of poor language achievement among twins J Speech Lang Hear Res 41 188 199 9493744
50. JB Tomblin NL Records P Buckwalter X Zhang E Smith M O'Brien 1997 Prevalence of specific language impairment in kindergarten children J Sp Hear Res 40 6 1245 1260
51. SC Vernes DF Newbury B Abrahams L Winchester J Nicod M Groszer M Alarcón P Oliver K Davies DH Geschwind AP Monaco S Fisher 2008 A functional genetic link between distinct developmental language disorders New Eng J Med 359 2337 2345 10.1056/NEJMoa0802828 18987363
52. A Whitehouse JG Barry DVM Bishop 2007 The broader language phenotype of autism: a comparison with specific language impairment J Child Psychol Psychiatry 48 822 830 10.1111/j.1469-7610.2007.01765.x 17683454
53. D Williams N Botting J Boucher 2008 Language in autism and specific language impairment: where are the links? Psychol Bull 134 6 944 963 10.1037/a0013743 18954162
54. World Health Organization (1993) The ICD-10 classification for mental and behavioural disorders: diagnostic criteria for research. WHO, Geneva