Synthesis and biological activity of flavanone derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 18, 2010, Pages 5466-5468

  Shi, Lei ^a   Feng, Xiu E ^a   Cui, Jing Rong ^b   Fang, Lian Hua ^c   Du, Guan Hua ^c   Li, Qing Shan ^a,b  

^a SHANXI MEDICAL UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

^c INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Anti tumor activity; Cytoprotective activity; Flavanone derivatives; PTK inhibitor; Synthesis; VSMC anti vegetation activity

Indexed keywords

CISPLATIN; FLAVANONE DERIVATIVE; GENISTEIN; HYDROGEN PEROXIDE; PROTEIN TYROSINE KINASE INHIBITOR; TETRANDRINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; ATHEROSCLEROSIS; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL PROTECTION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; PROTON NUCLEAR MAGNETIC RESONANCE; SMOOTH MUSCLE FIBER; STRUCTURE ACTIVITY RELATION; UMBILICAL VEIN; VASCULAR SMOOTH MUSCLE;

ANTINEOPLASTIC AGENTS; ATHEROSCLEROSIS; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOPROTECTION; ENDOTHELIAL CELLS; FLAVANONES; HUMANS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NEOPLASMS; PROTEIN-TYROSINE KINASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77956171708     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.07.090     Document Type: Article

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