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Volumn 3, Issue 2, 2010, Pages 81-84

Insulin-like growth factor type I receptor: A new target in the treatment of non-small cell lung cancer patients

Author keywords

CP 751,871; IGF IR; NSCLC

Indexed keywords

CARBOPLATIN; CP 751871; ERLOTINIB; GAMMA GLUTAMYLTRANSFERASE; INSULIN; ORAL ANTIDIABETIC AGENT; PACLITAXEL; PROTEIN TYROSINE KINASE INHIBITOR; SOMATOMEDIN; SOMATOMEDIN C RECEPTOR;

EID: 77956158984     PISSN: 18655041     EISSN: 18655076     Source Type: Journal    
DOI: 10.1007/s12254-010-0192-9     Document Type: Review
Times cited : (2)

References (26)
  • 1
    • 0028958031 scopus 로고
    • Insulin-like growth factors and their binding proteins: Biological actions
    • Jones JI, Clemmons DR. Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev, 16(1): 3-34, 1995.
    • (1995) Endocr Rev , vol.16 , Issue.1 , pp. 3-34
    • Jones, J.I.1    Clemmons, D.R.2
  • 2
    • 38849088141 scopus 로고    scopus 로고
    • The emerging role of the insulin-like growth factor pathway as a therapeutic target in cancer
    • Ryan PD, Goss PE. The emerging role of the insulin-like growth factor pathway as a therapeutic target in cancer. Oncologist, 13(1): 16-24, 2008.
    • (2008) Oncologist , vol.13 , Issue.1 , pp. 16-24
    • Ryan, P.D.1    Goss, P.E.2
  • 3
    • 0032565746 scopus 로고    scopus 로고
    • Role of insulin-like growth factor binding proteins in controlling IGF actions
    • Clemmons DR. Role of insulin-like growth factor binding proteins in controlling IGF actions. Mol Cell Endocrinol, 140(1-2): 19-24, 1998.
    • (1998) Mol Cell Endocrinol , vol.140 , Issue.1-2 , pp. 19-24
    • Clemmons, D.R.1
  • 4
    • 0034692430 scopus 로고    scopus 로고
    • Role of the insulin-like growth factor family in cancer development and progression
    • Yu H, Rohan T. Role of the insulin-like growth factor family in cancer development and progression. J Natl Cancer Inst, 92(18): 1472-1489, 2000.
    • (2000) J Natl Cancer Inst , vol.92 , Issue.18 , pp. 1472-1489
    • Yu, H.1    Rohan, T.2
  • 5
    • 0027512244 scopus 로고
    • The insulin and insulin-like growth factor-I receptor substrate IRS-1 associates with and activates phosphatidylinositol 3-kinase in vitro
    • Giorgetti S, Ballotti R, Kowalski-Chauvel A, Tartare S, Van Obberghen E. The insulin and insulin-like growth factor-I receptor substrate IRS-1 associates with and activates phosphatidylinositol 3-kinase in vitro. J Biol Chem, 268(10): 7358-7364, 1993.
    • (1993) J Biol Chem , vol.268 , Issue.10 , pp. 7358-7364
    • Giorgetti, S.1    Ballotti, R.2    Kowalski-Chauvel, A.3    Tartare, S.4    Van Obberghen, E.5
  • 6
    • 0034523626 scopus 로고    scopus 로고
    • Inhibition of mitogen-activated protein kinase kinase selectively inhibits cell proliferation in human breast cancer cells displaying enhanced insulin-like growth factor Imediated mitogen-activated protein kinase activation
    • Hermanto U, Zong CS, Wang LH. Inhibition of mitogen-activated protein kinase kinase selectively inhibits cell proliferation in human breast cancer cells displaying enhanced insulin-like growth factor Imediated mitogen-activated protein kinase activation. Cell Growth Differ, 11(12): 655-664, 2000.
    • (2000) Cell Growth Differ , vol.11 , Issue.12 , pp. 655-664
    • Hermanto, U.1    Zong, C.S.2    Wang, L.H.3
  • 7
    • 0242721096 scopus 로고    scopus 로고
    • Parallel phosphatidylinositol-3 kinase and p42/44 mitogen-activated protein kinase signaling pathways subserve the mitogenic and antiapoptotic actions of insulin-like growth factor I in osteoblastic cells
    • Grey A, Chen Q, Xu X, Callon K, Cornish J. Parallel phosphatidylinositol- 3 kinase and p42/44 mitogen-activated protein kinase signaling pathways subserve the mitogenic and antiapoptotic actions of insulin-like growth factor I in osteoblastic cells. Endocrinology, 144(11): 4886-4893, 2003.
    • (2003) Endocrinology , vol.144 , Issue.11 , pp. 4886-4893
    • Grey, A.1    Chen, Q.2    Xu, X.3    Callon, K.4    Cornish, J.5
  • 8
    • 0027407639 scopus 로고
    • Inhibition of growth of prostatic cancer cell lines by peptide analogues of insulin-like growth factor 1
    • Pietrzkowski Z, Mulholland G, Gomella L, Jameson BA, Wernicke D, Baserga R. Inhibition of growth of prostatic cancer cell lines by peptide analogues of insulin-like growth factor 1. Cancer Res, 53(5): 1102-1106, 1993.
    • (1993) Cancer Res , vol.53 , Issue.5 , pp. 1102-1106
    • Pietrzkowski, Z.1    Mulholland, G.2    Gomella, L.3    Jameson, B.A.4    Wernicke, D.5    Baserga, R.6
  • 10
    • 0029125689 scopus 로고
    • Growth inhibition of MCF-7 breast cancer cells by stable expression of an insulin-like growth factor I receptor antisense ribonucleic acid
    • Neuenschwander S, Roberts CT Jr, LeRoith D. Growth inhibition of MCF-7 breast cancer cells by stable expression of an insulin-like growth factor I receptor antisense ribonucleic acid. Endocrinology, 136(10): 4298-4303, 1995.
    • (1995) Endocrinology , vol.136 , Issue.10 , pp. 4298-4303
    • Neuenschwander, S.1    Roberts Jr., C.T.2    LeRoith, D.3
  • 11
    • 0033613356 scopus 로고    scopus 로고
    • Induction of tumor suppression and glandular differentiation of A549 lung carcinoma cells by dominant-negative IGF-I receptor
    • Jiang Y, Rom WN, Yie TA, Chi CX, Tchou-Wong KM. Induction of tumor suppression and glandular differentiation of A549 lung carcinoma cells by dominant-negative IGF-I receptor. Oncogene, 18(44): 6071-6077, 1999.
    • (1999) Oncogene , vol.18 , Issue.44 , pp. 6071-6077
    • Jiang, Y.1    Rom, W.N.2    Yie, T.A.3    Chi, C.X.4    Tchou-Wong, K.M.5
  • 12
    • 0033585421 scopus 로고    scopus 로고
    • Plasma levels of insulin-like growth factor-I and lung cancer risk: A case-control analysis
    • Yu H, Spitz MR, Mistry J, Gu J, Hong WK, Wu X. Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis. J Natl Cancer Inst, 91(2): 151-156, 1999.
    • (1999) J Natl Cancer Inst , vol.91 , Issue.2 , pp. 151-156
    • Yu, H.1    Spitz, M.R.2    Mistry, J.3    Gu, J.4    Hong, W.K.5    Wu, X.6
  • 13
    • 0034600258 scopus 로고    scopus 로고
    • Joint effect of insulin-like growth factors and mutagen sensitivity in lung cancer risk
    • Wu X, Yu H, Amos CI, Hong WK, Spitz MR. Joint effect of insulinlike growth factors and mutagen sensitivity in lung cancer risk. J Natl Cancer Inst, 92(9): 737-743, 2000. (Pubitemid 30365534)
    • (2000) Journal of the National Cancer Institute , vol.92 , Issue.9 , pp. 737-743
    • Wu, X.1    Yu, H.2    Amos, C.I.3    Hong, W.K.4    Spitz, M.R.5
  • 14
    • 70349755639 scopus 로고    scopus 로고
    • Elevated epithelial insulin-like growth factor expression is a risk factor for lung cancer development
    • Kim WY, Jin Q, Oh SH, Kim ES, Yang YJ, Lee DH, et al. Elevated epithelial insulin-like growth factor expression is a risk factor for lung cancer development. Cancer Res, 69(18): 7439-7448, 2009.
    • (2009) Cancer Res , vol.69 , Issue.18 , pp. 7439-7448
    • Kim, W.Y.1    Jin, Q.2    Oh, S.H.3    Kim, E.S.4    Yang, Y.J.5    Lee, D.H.6
  • 15
    • 65549158055 scopus 로고    scopus 로고
    • High coexpression of both insulin-like growth factor receptor-1 (IGFR-1) and epidermal growth factor receptor (EGFR) is associated with shorter disease-free survival in resected non-small-cell lung cancer patients
    • Ludovini V, Bellezza G, Pistola L, Bianconi F, Di Carlo L, Sidoni A, et al. High coexpression of both insulin-like growth factor receptor-1 (IGFR-1) and epidermal growth factor receptor (EGFR) is associated with shorter disease-free survival in resected non-small-cell lung cancer patients. Ann Oncol, 20(5): 842-849, 2009.
    • (2009) Ann Oncol , vol.20 , Issue.5 , pp. 842-849
    • Ludovini, V.1    Bellezza, G.2    Pistola, L.3    Bianconi, F.4    Di Carlo, L.5    Sidoni, A.6
  • 16
    • 33745615848 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor 1 (IGFR-1) is significantly associated with longer survival in non-small-cell lung cancer patients treated with gefitinib
    • Cappuzzo F, Toschi L, Tallini G, Ceresoli GL, Domenichini I, Bartolini S, et al. Insulin-like growth factor receptor 1 (IGFR-1) is significantly associated with longer survival in non-small-cell lung cancer patients treated with gefitinib. Ann Oncol, 17(7): 1120-1127, 2006.
    • (2006) Ann Oncol , vol.17 , Issue.7 , pp. 1120-1127
    • Cappuzzo, F.1    Toschi, L.2    Tallini, G.3    Ceresoli, G.L.4    Domenichini, I.5    Bartolini, S.6
  • 17
    • 77949579434 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor 1 (IGF1R) expression and survival in surgically resected non-small-cell lung cancer (NSCLC) patients
    • Cappuzzo F, Tallini G, Finocchiaro G, Wilson RS, Ligorio C, Giordano L, et al. Insulin-like growth factor receptor 1 (IGF1R) expression and survival in surgically resected non-small-cell lung cancer (NSCLC) patients. Ann Oncol, 21(3): 562-567, 2010.
    • (2010) Ann Oncol , vol.21 , Issue.3 , pp. 562-567
    • Cappuzzo, F.1    Tallini, G.2    Finocchiaro, G.3    Wilson, R.S.4    Ligorio, C.5    Giordano, L.6
  • 18
    • 77952309862 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor 1 (IGF1R) gene copy number is associated with survival in operable non-smallcell lung cancer: A comparison between IGF1R fluorescent in situ hybridization, protein expression, and mRNA expression
    • Dziadziuszko R, Merrick DT, Witta SE, Mendoza AD, Szostakiewicz B, Szymanowska A, et al. Insulin-like growth factor receptor 1 (IGF1R) gene copy number is associated with survival in operable non-smallcell lung cancer: a comparison between IGF1R fluorescent in situ hybridization, protein expression, and mRNA expression. J Clin Oncol, 28(13): 2174-2180, 2010.
    • (2010) J Clin Oncol , vol.28 , Issue.13 , pp. 2174-2180
    • Dziadziuszko, R.1    Merrick, D.T.2    Witta, S.E.3    Mendoza, A.D.4    Szostakiewicz, B.5    Szymanowska, A.6
  • 19
    • 0037096744 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-3 inhibits the growth of non-small cell lung cancer
    • Lee HY, Chun KH, Liu B, Wiehle SA, Cristiano RJ, Hong WK, et al. Insulin-like growth factor binding protein-3 inhibits the growth of non-small cell lung cancer. Cancer Res, 62(12): 3530-3537, 2002.
    • (2002) Cancer Res , vol.62 , Issue.12 , pp. 3530-3537
    • Lee, H.Y.1    Chun, K.H.2    Liu, B.3    Wiehle, S.A.4    Cristiano, R.J.5    Hong, W.K.6
  • 20
    • 23044493251 scopus 로고    scopus 로고
    • Blocking the insulin-like growth factor-I receptor as a strategy for targeting cancer
    • Hofmann F, Garcia-Echeverria C. Blocking the insulin-like growth factor-I receptor as a strategy for targeting cancer. Drug Discov Today, 10(15): 1041-1047, 2005.
    • (2005) Drug Discov Today , vol.10 , Issue.15 , pp. 1041-1047
    • Hofmann, F.1    Garcia-Echeverria, C.2
  • 21
    • 20144386856 scopus 로고    scopus 로고
    • Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751 871
    • Cohen BD, Baker DA, Soderstrom C, Tkalcevic G, Rossi AM, Miller PE, et al. Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871. Clin Cancer Res, 11(5): 2063-2073, 2005.
    • (2005) Clin Cancer Res , vol.11 , Issue.5 , pp. 2063-2073
    • Cohen, B.D.1    Baker, D.A.2    Soderstrom, C.3    Tkalcevic, G.4    Rossi, A.M.5    Miller, P.E.6
  • 22
    • 35348815620 scopus 로고    scopus 로고
    • Phase I dose escalation study of the anti insulin-like growth factor-I receptor monoclonal antibody CP-751,871 in patients with refractory solid tumors
    • Haluska P, Shaw HM, Batzel GN, Yin D, Molina JR, Molife LR, et al. Phase I dose escalation study of the anti insulin-like growth factor-I receptor monoclonal antibody CP-751,871 in patients with refractory solid tumors. Clin Cancer Res, 13(19): 5834-5840, 2007.
    • (2007) Clin Cancer Res , vol.13 , Issue.19 , pp. 5834-5840
    • Haluska, P.1    Shaw, H.M.2    Batzel, G.N.3    Yin, D.4    Molina, J.R.5    Molife, L.R.6
  • 23
    • 70449556274 scopus 로고    scopus 로고
    • Safety, pharmacokinetics, and pharmacodynamics of the insulin-like growth factor type 1 receptor inhibitor figitumumab (CP-751871) in combination with paclitaxel and carboplatin
    • Karp DD, Pollak MN, Cohen RB, Eisenberg PD, Haluska P, Yin D, et al. Safety, pharmacokinetics, and pharmacodynamics of the insulin-like growth factor type 1 receptor inhibitor figitumumab (CP-751,871) in combination with paclitaxel and carboplatin. J Thorac Oncol, 4(11): 1397-1403, 2009.
    • (2009) J Thorac Oncol , vol.4 , Issue.11 , pp. 1397-1403
    • Karp, D.D.1    Pollak, M.N.2    Cohen, R.B.3    Eisenberg, P.D.4    Haluska, P.5    Yin, D.6
  • 24
    • 69349103706 scopus 로고    scopus 로고
    • Inhibition of insulin-like growth factor 1 receptor by CP-751,871 radiosensitizes non-small cell lung cancer cells
    • Iwasa T, Okamoto I, Suzuki M, Hatashita E, Yamada Y, Fukuoka M, et al. Inhibition of insulin-like growth factor 1 receptor by CP-751,871 radiosensitizes non-small cell lung cancer cells. Clin Cancer Res, 15(16): 5117-5125, 2009.
    • (2009) Clin Cancer Res , vol.15 , Issue.16 , pp. 5117-5125
    • Iwasa, T.1    Okamoto, I.2    Suzuki, M.3    Hatashita, E.4    Yamada, Y.5    Fukuoka, M.6
  • 25
    • 66349091290 scopus 로고    scopus 로고
    • Phase II study of the anti-insulin-like growth factor type 1 receptor antibody CP-751,871 in combination with paclitaxel and carboplatin in previously untreated, locally advanced, or metastatic non-small-cell lung cancer
    • Karp DD, Paz-Ares LG, Novello S, Haluska P, Garland L, Cardenal F, et al. Phase II study of the anti-insulin-like growth factor type 1 receptor antibody CP-751,871 in combination with paclitaxel and carboplatin in previously untreated, locally advanced, or metastatic non-small-cell lung cancer. J Clin Oncol, 27(15): 2516-2522, 2009.
    • (2009) J Clin Oncol , vol.27 , Issue.15 , pp. 2516-2522
    • Karp, D.D.1    Paz-Ares, L.G.2    Novello, S.3    Haluska, P.4    Garland, L.5    Cardenal, F.6
  • 26
    • 52649147602 scopus 로고    scopus 로고
    • Clinical significance of insulin-like growth factor-1 receptor expression in stage I non-small-cell lung cancer: Immunohistochemical analysis
    • Lee CY, Jeon JH, Kim HJ, Shin DH, Roh TW, Ahn CM, et al. Clinical significance of insulin-like growth factor-1 receptor expression in stage I non-small-cell lung cancer: immunohistochemical analysis. Korean J Intern Med, 23(3): 116-120, 2008.
    • (2008) Korean J Intern Med , vol.23 , Issue.3 , pp. 116-120
    • Lee, C.Y.1    Jeon, J.H.2    Kim, H.J.3    Shin, D.H.4    Roh, T.W.5    Ahn, C.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.