-
1
-
-
0030066368
-
Randomised placebo-controlled study of stopping second-line drugs in rheumatoid arthritis
-
S. ten Wolde, F.C. Breedveld, and J. Hermans Randomised placebo-controlled study of stopping second-line drugs in rheumatoid arthritis Lancet 347 8998 1996 347 352
-
(1996)
Lancet
, vol.347
, Issue.8998
, pp. 347-352
-
-
Ten Wolde, S.1
Breedveld, F.C.2
Hermans, J.3
-
2
-
-
0024353080
-
Manipulation of T-cell responses with monoclonal antibodies
-
H. Waldmann Manipulation of T-cell responses with monoclonal antibodies Annu Rev Immunol 7 1989 407 444
-
(1989)
Annu Rev Immunol
, vol.7
, pp. 407-444
-
-
Waldmann, H.1
-
3
-
-
0027479685
-
"Infectious" transplantation tolerance
-
S. Qin, S.P. Cobbold, and H. Pope "Infectious" transplantation tolerance Science 259 5097 1993 974 977
-
(1993)
Science
, vol.259
, Issue.5097
, pp. 974-977
-
-
Qin, S.1
Cobbold, S.P.2
Pope, H.3
-
4
-
-
0029659048
-
Mechanisms of peripheral tolerance and suppression induced by monoclonal antibodies to CD4 and CD8
-
S.P. Cobbold, E. Adams, and S.E. Marshall Mechanisms of peripheral tolerance and suppression induced by monoclonal antibodies to CD4 and CD8 Immunol Rev 149 1996 5 33
-
(1996)
Immunol Rev
, vol.149
, pp. 5-33
-
-
Cobbold, S.P.1
Adams, E.2
Marshall, S.E.3
-
5
-
-
33748572608
-
Aspects of early arthritis. Definition of disease states in early arthritis: Remission versus minimal disease activity
-
A. van der Helm-van Mil, F. Breedveld, and T. Huizinga Aspects of early arthritis. Definition of disease states in early arthritis: remission versus minimal disease activity Arthritis Research & Therapy 8 4 2006 216
-
(2006)
Arthritis Research & Therapy
, vol.8
, Issue.4
, pp. 216
-
-
Van Der Helm-Van Mil, A.1
Breedveld, F.2
Huizinga, T.3
-
7
-
-
33845882484
-
Biologic therapies in rheumatology: Lessons learned, future directions
-
V. Strand, R. Kimberly, and J.D. Isaacs Biologic therapies in rheumatology: lessons learned, future directions Nat Rev Drug Discov 6 1 2007 75 92
-
(2007)
Nat Rev Drug Discov
, vol.6
, Issue.1
, pp. 75-92
-
-
Strand, V.1
Kimberly, R.2
Isaacs, J.D.3
-
8
-
-
0026783632
-
Humanised monoclonal antibody therapy for rheumatoid arthritis
-
J.D. Isaacs, R.A. Watts, and B.L. Hazleman Humanised monoclonal antibody therapy for rheumatoid arthritis Lancet 340 1992 748 752
-
(1992)
Lancet
, vol.340
, pp. 748-752
-
-
Isaacs, J.D.1
Watts, R.A.2
Hazleman, B.L.3
-
9
-
-
0029875268
-
CAMPATH-1H in rheumatoid arthritis-an intravenous dose-ranging study
-
J.D. Isaacs, V.K. Manna, and N. Rapson CAMPATH-1H in rheumatoid arthritis-an intravenous dose-ranging study Br J Rheumatol 35 3 1996 231 240
-
(1996)
Br J Rheumatol
, vol.35
, Issue.3
, pp. 231-240
-
-
Isaacs, J.D.1
Manna, V.K.2
Rapson, N.3
-
10
-
-
0035465242
-
Morbidity and mortality in rheumatoid arthritis patients with profound and prolonged therapy-induced lymphopenia
-
J.D. Isaacs, S. Greer, and S. Sharma Morbidity and mortality in rheumatoid arthritis patients with profound and prolonged therapy-induced lymphopenia Arthritis Rheum 44 2001 1998 2008
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1998-2008
-
-
Isaacs, J.D.1
Greer, S.2
Sharma, S.3
-
11
-
-
39749114393
-
Morbidity and mortality in rheumatoid arthritis patients with prolonged therapy-induced lymphopenia: Twelve-year outcomes
-
A.R. Lorenzi, A.M. Clarke, and T. Wooldridge Morbidity and mortality in rheumatoid arthritis patients with prolonged therapy-induced lymphopenia: Twelve-year outcomes Arthritis Rheum 58 2 2008 370 375
-
(2008)
Arthritis Rheum
, vol.58
, Issue.2
, pp. 370-375
-
-
Lorenzi, A.R.1
Clarke, A.M.2
Wooldridge, T.3
-
12
-
-
0025339511
-
A cell culture model for T lymphocyte clonal anergy
-
R.H. Schwartz A cell culture model for T lymphocyte clonal anergy Science 248 4961 1990 1349 1356
-
(1990)
Science
, vol.248
, Issue.4961
, pp. 1349-1356
-
-
Schwartz, R.H.1
-
13
-
-
41849120516
-
Efficacy and safety of the selective co-stimulation modulator abatacept following 2 years of treatment in patients with rheumatoid arthritis and an inadequate response to anti-TNF therapy
-
M.C. Genovese, M. Schiff, and M. Luggen Efficacy and safety of the selective co-stimulation modulator abatacept following 2 years of treatment in patients with rheumatoid arthritis and an inadequate response to anti-TNF therapy Ann Rheum Dis 67 4 2008 547 554
-
(2008)
Ann Rheum Dis
, vol.67
, Issue.4
, pp. 547-554
-
-
Genovese, M.C.1
Schiff, M.2
Luggen, M.3
-
14
-
-
0025602264
-
The induction of skin graft tolerance in major histocompatibility complex-mismatched or primed recipients: Primed T cells can be tolerized in the periphery with anti-CD4 and anti-CD8 antibodies
-
S.P. Cobbold, G. Martin, and H. Waldmann The induction of skin graft tolerance in major histocompatibility complex-mismatched or primed recipients: primed T cells can be tolerized in the periphery with anti-CD4 and anti-CD8 antibodies Eur J Immunol 20 12 1990 2747 2755
-
(1990)
Eur J Immunol
, vol.20
, Issue.12
, pp. 2747-2755
-
-
Cobbold, S.P.1
Martin, G.2
Waldmann, H.3
-
15
-
-
10344263909
-
Prope tolerance-the future of organ transplantation from the laboratory to the clinic
-
R.Y. Calne Prope tolerance-the future of organ transplantation from the laboratory to the clinic Int Immunopharmacol 5 1 2005 163 167
-
(2005)
Int Immunopharmacol
, vol.5
, Issue.1
, pp. 163-167
-
-
Calne, R.Y.1
-
16
-
-
34247620262
-
Clinical transplantation tolerance: Many rivers to cross
-
A.D. Salama, K.L. Womer, and M.H. Sayegh Clinical transplantation tolerance: many rivers to cross J Immunol 178 9 2007 5419 5423
-
(2007)
J Immunol
, vol.178
, Issue.9
, pp. 5419-5423
-
-
Salama, A.D.1
Womer, K.L.2
Sayegh, M.H.3
-
17
-
-
55649124879
-
Clinical experience with mixed chimerism to induce transplantation tolerance
-
T. Fehr, and M. Sykes Clinical experience with mixed chimerism to induce transplantation tolerance Transpl Int 21 12 2008 1118 1135
-
(2008)
Transpl Int
, vol.21
, Issue.12
, pp. 1118-1135
-
-
Fehr, T.1
Sykes, M.2
-
18
-
-
67649847906
-
Towards the identification of biomarkers of transplantation tolerance
-
L.A. Turka, and R.I. Lechler Towards the identification of biomarkers of transplantation tolerance Nat Rev Immunol 9 7 2009 521 526
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.7
, pp. 521-526
-
-
Turka, L.A.1
Lechler, R.I.2
-
19
-
-
41149123473
-
A pilot study of combination anti-cytokine and anti-lymphocyte biological therapy in rheumatoid arthritis
-
A.W. Morgan, G. Hale, and P.R.U.B. Rebello A pilot study of combination anti-cytokine and anti-lymphocyte biological therapy in rheumatoid arthritis Quarterly Journal of Medicine 101 4 2008 299 306
-
(2008)
Quarterly Journal of Medicine
, vol.101
, Issue.4
, pp. 299-306
-
-
Morgan, A.W.1
Hale, G.2
Rebello, P.R.U.B.3
-
20
-
-
53049099026
-
From mice to men: The challenges of developing tolerance-inducing biological drugs for the clinic
-
W.-F. Ng, and J.D. Isaacs From mice to men: the challenges of developing tolerance-inducing biological drugs for the clinic L. Graca, The Immune Synapse as a Novel Target for Therapy 2008 Birkhauser Verlag AG Basle - Boston - Berlin 169 185
-
(2008)
The Immune Synapse As A Novel Target for Therapy
, pp. 169-185
-
-
Ng, W.-F.1
Isaacs, J.D.2
-
21
-
-
0034663755
-
Differential effects of cyclosporine A, methylprednisolone, mycophenolate, and rapamycin on CD154 induction and requirement for NFkappaB: Implications for tolerance induction
-
S.T. Smiley, V. Csizmadia, and W. Gao Differential effects of cyclosporine A, methylprednisolone, mycophenolate, and rapamycin on CD154 induction and requirement for NFkappaB: implications for tolerance induction Transplantation 70 3 2000 415 419
-
(2000)
Transplantation
, vol.70
, Issue.3
, pp. 415-419
-
-
Smiley, S.T.1
Csizmadia, V.2
Gao, W.3
-
22
-
-
31544482746
-
Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells
-
J.J. Coenen, H.J. Koenen, and E. van Rijssen Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells Blood 107 3 2006 1018 1023
-
(2006)
Blood
, vol.107
, Issue.3
, pp. 1018-1023
-
-
Coenen, J.J.1
Koenen, H.J.2
Van Rijssen, E.3
-
23
-
-
64649092922
-
Rapamycin prevents and breaks the anti-CD3-induced tolerance in NOD mice
-
A. Valle, T. Jofra, and A. Stabilini Rapamycin prevents and breaks the anti-CD3-induced tolerance in NOD mice Diabetes 58 4 2009 875 881
-
(2009)
Diabetes
, vol.58
, Issue.4
, pp. 875-881
-
-
Valle, A.1
Jofra, T.2
Stabilini, A.3
-
24
-
-
0025788015
-
The anti-CD3-induced syndrome: A consequence of massive in vivo cell activation
-
L. Chatenoud, C. Ferran, and J.F. Bach The anti-CD3-induced syndrome: a consequence of massive in vivo cell activation Curr Top Microbiol Immunol 174 1991 121 134
-
(1991)
Curr Top Microbiol Immunol
, vol.174
, pp. 121-134
-
-
Chatenoud, L.1
Ferran, C.2
Bach, J.F.3
-
25
-
-
0037313086
-
CD3-specific antibody-induced active tolerance: From bench to bedside
-
L. Chatenoud CD3-specific antibody-induced active tolerance: from bench to bedside Nat Rev Immunol 3 2 2003 123 132
-
(2003)
Nat Rev Immunol
, vol.3
, Issue.2
, pp. 123-132
-
-
Chatenoud, L.1
-
26
-
-
27144483896
-
CD3-specific antibodies restore self-tolerance: Mechanisms and clinical applications
-
L. Chatenoud CD3-specific antibodies restore self-tolerance: mechanisms and clinical applications Curr Opin Immunol 17 6 2005 632 637
-
(2005)
Curr Opin Immunol
, vol.17
, Issue.6
, pp. 632-637
-
-
Chatenoud, L.1
-
27
-
-
0037198420
-
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus
-
K.C. Herold, W. Hagopian, and J.A. Auger Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus N Engl J Med 346 22 2002 1692 1698
-
(2002)
N Engl J Med
, vol.346
, Issue.22
, pp. 1692-1698
-
-
Herold, K.C.1
Hagopian, W.2
Auger, J.A.3
-
28
-
-
20544443927
-
Insulin Needs after CD3-Antibody Therapy in New-Onset Type 1 Diabetes
-
B. Keymeulen, E. Vandemeulebroucke, and A.G. Ziegler Insulin Needs after CD3-Antibody Therapy in New-Onset Type 1 Diabetes New Engl J Med 352 2005 2598 2608
-
(2005)
New Engl J Med
, vol.352
, pp. 2598-2608
-
-
Keymeulen, B.1
Vandemeulebroucke, E.2
Ziegler, A.G.3
-
29
-
-
20044375937
-
A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
-
K.C. Herold, S.E. Gitelman, and U. Masharani A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes Diabetes 54 6 2005 1763 1769
-
(2005)
Diabetes
, vol.54
, Issue.6
, pp. 1763-1769
-
-
Herold, K.C.1
Gitelman, S.E.2
Masharani, U.3
-
30
-
-
67649933375
-
Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb Teplizumab preserves insulin production for up to 5 years
-
K.C. Herold, S. Gitelman, and C. Greenbaum Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb Teplizumab preserves insulin production for up to 5 years Clin Immunol 132 2 2009 166 173
-
(2009)
Clin Immunol
, vol.132
, Issue.2
, pp. 166-173
-
-
Herold, K.C.1
Gitelman, S.2
Greenbaum, C.3
-
31
-
-
1042290337
-
Specific autoantibodies precede the symptoms of rheumatoid arthritis: A study of serial measurements in blood donors
-
M.M. Nielen, D. van Schaardenburg, and H.W. Reesink Specific autoantibodies precede the symptoms of rheumatoid arthritis: a study of serial measurements in blood donors Arthritis Rheum 50 2 2004 380 386
-
(2004)
Arthritis Rheum
, vol.50
, Issue.2
, pp. 380-386
-
-
Nielen, M.M.1
Van Schaardenburg, D.2
Reesink, H.W.3
-
32
-
-
0037314237
-
Activation of human T cells by FcR nonbinding anti-CD3 mAb, hOKT3gamma1(Ala-Ala)
-
K.C. Herold, J.B. Burton, and F. Francois Activation of human T cells by FcR nonbinding anti-CD3 mAb, hOKT3gamma1(Ala-Ala) J Clin Invest 111 3 2003 409 418
-
(2003)
J Clin Invest
, vol.111
, Issue.3
, pp. 409-418
-
-
Herold, K.C.1
Burton, J.B.2
Francois, F.3
-
33
-
-
26444515022
-
TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs
-
B. Bisikirska, J. Colgan, and J. Luban TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs J Clin Invest 115 10 2005 2904 2913
-
(2005)
J Clin Invest
, vol.115
, Issue.10
, pp. 2904-2913
-
-
Bisikirska, B.1
Colgan, J.2
Luban, J.3
-
34
-
-
73349105249
-
Monitoring of antigen-specific CD8 T cells in patients with type 1 diabetes treated with antiCD3 monoclonal antibodies
-
S. Cernea, and K.C. Herold Monitoring of antigen-specific CD8 T cells in patients with type 1 diabetes treated with antiCD3 monoclonal antibodies Clin Immunol 134 2 2010 Feb 121 129
-
(2010)
Clin Immunol
, vol.134
, Issue.2
, pp. 121-129
-
-
Cernea, S.1
Herold, K.C.2
-
35
-
-
33646392755
-
Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs
-
D. Bresson, L. Togher, and E. Rodrigo Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs J Clin Invest 116 5 2006 1371 1381
-
(2006)
J Clin Invest
, vol.116
, Issue.5
, pp. 1371-1381
-
-
Bresson, D.1
Togher, L.2
Rodrigo, E.3
-
36
-
-
33748416499
-
Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412
-
G. Suntharalingam, M.R. Perry, and S. Ward Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412 N Engl J Med 355 10 2006 1018 1028
-
(2006)
N Engl J Med
, vol.355
, Issue.10
, pp. 1018-1028
-
-
Suntharalingam, G.1
Perry, M.R.2
Ward, S.3
-
37
-
-
37749032491
-
Cytokine Storm' in the Phase i Trial of Monoclonal Antibody TGN1412: Better Understanding the Causes to Improve PreClinical Testing of Immunotherapeutics
-
R. Stebbings, L. Findlay, and C. Edwards Cytokine Storm' in the Phase I Trial of Monoclonal Antibody TGN1412: Better Understanding the Causes to Improve PreClinical Testing of Immunotherapeutics J Immunol 179 5 2007 3325 3331
-
(2007)
J Immunol
, vol.179
, Issue.5
, pp. 3325-3331
-
-
Stebbings, R.1
Findlay, L.2
Edwards, C.3
-
38
-
-
0029869119
-
Transient increase in symptoms associated with cytokine release in patients with multiple sclerosis
-
T. Moreau, A. Coles, and M. Wing Transient increase in symptoms associated with cytokine release in patients with multiple sclerosis Brain 119 1996 225 237
-
(1996)
Brain
, vol.119
, pp. 225-237
-
-
Moreau, T.1
Coles, A.2
Wing, M.3
-
39
-
-
54449089342
-
In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner
-
H. Albert, M. Collin, and D. Dudziak In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner Proc Natl Acad Sci U S A 105 39 2008 15005 15009
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.39
, pp. 15005-15009
-
-
Albert, H.1
Collin, M.2
Dudziak, D.3
-
40
-
-
35648941736
-
A phase i study of visilizumab, a humanized anti-CD3 monoclonal antibody, in severe steroid-refractory ulcerative colitis
-
S. Plevy, B. Salzberg, and G. Van Assche A phase I study of visilizumab, a humanized anti-CD3 monoclonal antibody, in severe steroid-refractory ulcerative colitis Gastroenterology 133 5 2007 1414 1422
-
(2007)
Gastroenterology
, vol.133
, Issue.5
, pp. 1414-1422
-
-
Plevy, S.1
Salzberg, B.2
Van Assche, G.3
-
41
-
-
54949143968
-
Alemtuzumab vs. interferon beta-1a in early multiple sclerosis
-
A.J. Coles, D.A. Compston, and K.W. Selmaj Alemtuzumab vs. interferon beta-1a in early multiple sclerosis N Engl J Med 359 17 2008 1786 1801
-
(2008)
N Engl J Med
, vol.359
, Issue.17
, pp. 1786-1801
-
-
Coles, A.J.1
Compston, D.A.2
Selmaj, K.W.3
-
42
-
-
0033552391
-
Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis
-
A.J. Coles, M. Wing, and S. Smith Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis Lancet 354 9191 1999 1691 1695
-
(1999)
Lancet
, vol.354
, Issue.9191
, pp. 1691-1695
-
-
Coles, A.J.1
Wing, M.2
Smith, S.3
-
43
-
-
50249107909
-
Long-term follow-up of relapsing/refractory anti-neutrophil cytoplasm antibody associated vasculitis treated with the lymphocyte depleting antibody alemtuzumab (CAMPATH-1H)
-
M. Walsh, A. Chaudhry, and D. Jayne Long-term follow-up of relapsing/refractory anti-neutrophil cytoplasm antibody associated vasculitis treated with the lymphocyte depleting antibody alemtuzumab (CAMPATH-1H) Ann Rheum Dis 67 9 2008 1322 1327
-
(2008)
Ann Rheum Dis
, vol.67
, Issue.9
, pp. 1322-1327
-
-
Walsh, M.1
Chaudhry, A.2
Jayne, D.3
-
44
-
-
0345099473
-
Remission induction in Behcet's disease following lymphocyte depletion by the anti-CD52 antibody CAMPATH 1-H
-
C.M. Lockwood, G. Hale, and H. Waldman Remission induction in Behcet's disease following lymphocyte depletion by the anti-CD52 antibody CAMPATH 1-H Rheumatology (Oxford) 42 12 2003 1539 1544
-
(2003)
Rheumatology (Oxford)
, vol.42
, Issue.12
, pp. 1539-1544
-
-
Lockwood, C.M.1
Hale, G.2
Waldman, H.3
-
45
-
-
33745279073
-
Autoimmune thyroid disease after renal transplantation using depletional induction with alemtuzumab
-
A.D. Kirk, D.A. Hale, and S.J. Swanson Autoimmune thyroid disease after renal transplantation using depletional induction with alemtuzumab Am J Transplant 6 5 Pt 1 2006 1084 1085
-
(2006)
Am J Transplant
, vol.6
, Issue.5 PART 1
, pp. 1084-1085
-
-
Kirk, A.D.1
Hale, D.A.2
Swanson, S.J.3
-
46
-
-
34247121380
-
Autoimmunity following haematopoietic stem-cell transplantation
-
T. Daikeler, and A. Tyndall Autoimmunity following haematopoietic stem-cell transplantation Best Pract Res Clin Haematol 20 2 2007 349 360
-
(2007)
Best Pract Res Clin Haematol
, vol.20
, Issue.2
, pp. 349-360
-
-
Daikeler, T.1
Tyndall, A.2
-
47
-
-
68849084141
-
IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H)
-
J.L. Jones, C.L. Phuah, and A.L. Cox IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H) J Clin Invest 119 7 2009 2052 2061
-
(2009)
J Clin Invest
, vol.119
, Issue.7
, pp. 2052-2061
-
-
Jones, J.L.1
Phuah, C.L.2
Cox, A.L.3
-
48
-
-
33947249410
-
Regulatory T cells and T cell depletion: Role of immunosuppressive drugs
-
M. Noris, F. Casiraghi, and M. Todeschini Regulatory T cells and T cell depletion: role of immunosuppressive drugs J Am Soc Nephrol 18 3 2007 1007 1018
-
(2007)
J Am Soc Nephrol
, vol.18
, Issue.3
, pp. 1007-1018
-
-
Noris, M.1
Casiraghi, F.2
Todeschini, M.3
-
49
-
-
33745861719
-
Rapamycin-mediated enrichment of T cells with regulatory activity in stimulated CD4+ T cell cultures is not due to the selective expansion of naturally occurring regulatory T cells but to the induction of regulatory functions in conventional CD4+ T cells
-
D. Valmori, V. Tosello, and N.E. Souleimanian Rapamycin-mediated enrichment of T cells with regulatory activity in stimulated CD4+ T cell cultures is not due to the selective expansion of naturally occurring regulatory T cells but to the induction of regulatory functions in conventional CD4+ T cells J Immunol 177 2 2006 944 949
-
(2006)
J Immunol
, vol.177
, Issue.2
, pp. 944-949
-
-
Valmori, D.1
Tosello, V.2
Souleimanian, N.E.3
-
50
-
-
33845379986
-
Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients
-
M. Battaglia, A. Stabilini, and B. Migliavacca Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients J Immunol 177 12 2006 8338 8347
-
(2006)
J Immunol
, vol.177
, Issue.12
, pp. 8338-8347
-
-
Battaglia, M.1
Stabilini, A.2
Migliavacca, B.3
-
51
-
-
37349080895
-
Sirolimus versus cyclosporine therapy increases circulating regulatory T cells, but does not protect renal transplant patients given alemtuzumab induction from chronic allograft injury
-
P. Ruggenenti, N. Perico, and E. Gotti Sirolimus versus cyclosporine therapy increases circulating regulatory T cells, but does not protect renal transplant patients given alemtuzumab induction from chronic allograft injury Transplantation 84 8 2007 956 964
-
(2007)
Transplantation
, vol.84
, Issue.8
, pp. 956-964
-
-
Ruggenenti, P.1
Perico, N.2
Gotti, E.3
-
52
-
-
24744438448
-
The effect of Fel d 1-derived T-cell peptides on upper and lower airway outcome measurements in cat-allergic subjects
-
C. Alexander, M. Tarzi, and M. Larche The effect of Fel d 1-derived T-cell peptides on upper and lower airway outcome measurements in cat-allergic subjects Allergy 60 10 2005 1269 1274
-
(2005)
Allergy
, vol.60
, Issue.10
, pp. 1269-1274
-
-
Alexander, C.1
Tarzi, M.2
Larche, M.3
-
53
-
-
18244391173
-
T cell epitope immunotherapy induces a CD4+ T cell population with regulatory activity
-
A. Verhoef, C. Alexander, and A.B. Kay T cell epitope immunotherapy induces a CD4+ T cell population with regulatory activity PLoS Med 2 3 2005 e78
-
(2005)
PLoS Med
, vol.2
, Issue.3
, pp. 78
-
-
Verhoef, A.1
Alexander, C.2
Kay, A.B.3
-
54
-
-
67650492400
-
Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression
-
J.D. Campbell, K.F. Buckland, and S.J. McMillan Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression J Exp Med 206 7 2009 1535 1547
-
(2009)
J Exp Med
, vol.206
, Issue.7
, pp. 1535-1547
-
-
Campbell, J.D.1
Buckland, K.F.2
McMillan, S.J.3
-
55
-
-
69249212422
-
Immune modulation in type 1 diabetes mellitus using DiaPep277: A short review and update of recent clinical trial results
-
R. Eldor, S. Kassem, and I. Raz Immune modulation in type 1 diabetes mellitus using DiaPep277: a short review and update of recent clinical trial results Diabetes Metab Res Rev 25 4 2009 316 320
-
(2009)
Diabetes Metab Res Rev
, vol.25
, Issue.4
, pp. 316-320
-
-
Eldor, R.1
Kassem, S.2
Raz, I.3
-
56
-
-
34248589182
-
Differential recognition of heat-shock protein dnaJ-derived epitopes by effector and Treg cells leads to modulation of inflammation in juvenile idiopathic arthritis
-
M. Massa, M. Passalia, and S.M. Manzoni Differential recognition of heat-shock protein dnaJ-derived epitopes by effector and Treg cells leads to modulation of inflammation in juvenile idiopathic arthritis Arthritis Rheum 56 5 2007 1648 1657
-
(2007)
Arthritis Rheum
, vol.56
, Issue.5
, pp. 1648-1657
-
-
Massa, M.1
Passalia, M.2
Manzoni, S.M.3
-
57
-
-
67650079430
-
Pan-DR-binding Hsp60 self epitopes induce an interleukin-10-mediated immune response in rheumatoid arthritis
-
H. de Jong, F.F. Lafeber, and W. de Jager Pan-DR-binding Hsp60 self epitopes induce an interleukin-10-mediated immune response in rheumatoid arthritis Arthritis Rheum 60 7 2009 1966 1976
-
(2009)
Arthritis Rheum
, vol.60
, Issue.7
, pp. 1966-1976
-
-
De Jong, H.1
Lafeber, F.F.2
De Jager, W.3
-
58
-
-
33748988721
-
Peptide p277 of HSP60 signals T cells: Inhibition of inflammatory chemotaxis
-
G. Nussbaum, A. Zanin-Zhorov, and F. Quintana Peptide p277 of HSP60 signals T cells: inhibition of inflammatory chemotaxis Int Immunol 18 10 2006 1413 1419
-
(2006)
Int Immunol
, vol.18
, Issue.10
, pp. 1413-1419
-
-
Nussbaum, G.1
Zanin-Zhorov, A.2
Quintana, F.3
-
59
-
-
0033786776
-
Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand
-
B. Bielekova, B. Goodwin, and N. Richert Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand Nat Med 6 10 2000 1167 1175
-
(2000)
Nat Med
, vol.6
, Issue.10
, pp. 1167-1175
-
-
Bielekova, B.1
Goodwin, B.2
Richert, N.3
-
60
-
-
77954899973
-
Intranasal administration of recombinant Human Cartilage glycoprotein-39 as a treatment for rheumatoid arthritis: A Phase II, multicenter, double-blind, randomized, placebo-controlled, parallel group dose-finding trial
-
R.B. Landewe, J.G. Houbiers, and F.E. Van den Bosch Intranasal administration of recombinant Human Cartilage glycoprotein-39 as a treatment for rheumatoid arthritis: A Phase II, multicenter, double-blind, randomized, placebo-controlled, parallel group dose-finding trial Ann Rheum Dis 2009
-
(2009)
Ann Rheum Dis
-
-
Landewe, R.B.1
Houbiers, J.G.2
Van Den Bosch, F.E.3
-
61
-
-
68249096707
-
Retuning the immune system: The future of type 1 diabetes therapy?
-
D. Jones Retuning the immune system: the future of type 1 diabetes therapy? Nat Rev Drug Discov 8 8 2009 600 601
-
(2009)
Nat Rev Drug Discov
, vol.8
, Issue.8
, pp. 600-601
-
-
Jones, D.1
-
62
-
-
12144286975
-
Autologous hemopoietic stem cell transplantation in severe rheumatoid arthritis: A report from the EBMT and ABMTR
-
J.A. Snowden, J. Passweg, and J.J. Moore Autologous hemopoietic stem cell transplantation in severe rheumatoid arthritis: a report from the EBMT and ABMTR J Rheumatol 31 3 2004 482 488
-
(2004)
J Rheumatol
, vol.31
, Issue.3
, pp. 482-488
-
-
Snowden, J.A.1
Passweg, J.2
Moore, J.J.3
-
63
-
-
32644442191
-
Autologous stem cell transplantation for autoimmunity induces immunologic self-tolerance by reprogramming autoreactive T cells and restoring the CD4+CD25+ immune regulatory network
-
I. de Kleer, B. Vastert, and M. Klein Autologous stem cell transplantation for autoimmunity induces immunologic self-tolerance by reprogramming autoreactive T cells and restoring the CD4+CD25+ immune regulatory network Blood 107 4 2006 1696 1702
-
(2006)
Blood
, vol.107
, Issue.4
, pp. 1696-1702
-
-
De Kleer, I.1
Vastert, B.2
Klein, M.3
-
64
-
-
34547458668
-
Autologous stem cell transplantation in children with severe progressive systemic or polyarticular juvenile idiopathic arthritis: Long-term follow-up of a prospective clinical trial
-
D.M. Brinkman, I.M. de Kleer, and R. ten Cate Autologous stem cell transplantation in children with severe progressive systemic or polyarticular juvenile idiopathic arthritis: long-term follow-up of a prospective clinical trial Arthritis Rheum 56 7 2007 2410 2421
-
(2007)
Arthritis Rheum
, vol.56
, Issue.7
, pp. 2410-2421
-
-
Brinkman, D.M.1
De Kleer, I.M.2
Ten Cate, R.3
-
65
-
-
59449092041
-
Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system
-
T. Alexander, A. Thiel, and O. Rosen Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system Blood 113 1 2009 214 223
-
(2009)
Blood
, vol.113
, Issue.1
, pp. 214-223
-
-
Alexander, T.1
Thiel, A.2
Rosen, O.3
-
66
-
-
20144386375
-
Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients
-
P.A. Muraro, D.C. Douek, and A. Packer Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients J Exp Med 201 5 2005 805 816
-
(2005)
J Exp Med
, vol.201
, Issue.5
, pp. 805-816
-
-
Muraro, P.A.1
Douek, D.C.2
Packer, A.3
-
67
-
-
27744550642
-
Outcome of intensive immunosuppression and autologous stem cell transplantation in patients with severe rheumatoid arthritis is associated with the composition of synovial T cell infiltration
-
R.J. Verburg, R. Flierman, and J.K. Sont Outcome of intensive immunosuppression and autologous stem cell transplantation in patients with severe rheumatoid arthritis is associated with the composition of synovial T cell infiltration Ann Rheum Dis 64 10 2005 1397 1405
-
(2005)
Ann Rheum Dis
, vol.64
, Issue.10
, pp. 1397-1405
-
-
Verburg, R.J.1
Flierman, R.2
Sont, J.K.3
-
68
-
-
0037114690
-
Dysregulated lymphocyte proliferation and differentiation in patients with rheumatoid arthritis
-
F. Ponchel, A.W. Morgan, and S.J. Bingham Dysregulated lymphocyte proliferation and differentiation in patients with rheumatoid arthritis Blood 100 2002 4550 4556
-
(2002)
Blood
, vol.100
, pp. 4550-4556
-
-
Ponchel, F.1
Morgan, A.W.2
Bingham, S.J.3
-
69
-
-
13444268243
-
Interleukin-7 deficiency in rheumatoid arthritis: Consequences for therapy-induced lymphopenia
-
F. Ponchel, R.J. Verburg, and S.J. Bingham Interleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia Arthritis Res Ther 7 2005 R80 92
-
(2005)
Arthritis Res Ther
, vol.7
, pp. 80-92
-
-
Ponchel, F.1
Verburg, R.J.2
Bingham, S.J.3
-
70
-
-
3543140687
-
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNF alpha therapy
-
M.R. Ehrenstein, J.G. Evans, and A. Singh Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNF alpha therapy J Exp Med 200 2004 277 285
-
(2004)
J Exp Med
, vol.200
, pp. 277-285
-
-
Ehrenstein, M.R.1
Evans, J.G.2
Singh, A.3
-
71
-
-
19344374510
-
Impaired early B cell tolerance in patients with rheumatoid arthritis
-
J. Samuels, Y.S. Ng, and C. Coupillaud Impaired early B cell tolerance in patients with rheumatoid arthritis J Exp Med 201 10 2005 1659 1667
-
(2005)
J Exp Med
, vol.201
, Issue.10
, pp. 1659-1667
-
-
Samuels, J.1
Ng, Y.S.2
Coupillaud, C.3
-
72
-
-
4043060855
-
Nonmyeloablative allogeneic hematopoietic stem cell transplantation for autoimmune disease
-
S.Z. Pavletic Nonmyeloablative allogeneic hematopoietic stem cell transplantation for autoimmune disease Arthritis Rheum 50 8 2004 2387 2390
-
(2004)
Arthritis Rheum
, vol.50
, Issue.8
, pp. 2387-2390
-
-
Pavletic, S.Z.1
-
73
-
-
34447108894
-
Hematopoietic growth factors including keratinocyte growth factor in allogeneic and autologous stem cell transplantation
-
R. Seggewiss, and H. Einsele Hematopoietic growth factors including keratinocyte growth factor in allogeneic and autologous stem cell transplantation Semin Hematol 44 3 2007 203 211
-
(2007)
Semin Hematol
, vol.44
, Issue.3
, pp. 203-211
-
-
Seggewiss, R.1
Einsele, H.2
-
74
-
-
23844455192
-
Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice
-
E.L. Masteller, M.R. Warner, and Q. Tang Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice J Immunol 175 5 2005 3053 3059
-
(2005)
J Immunol
, vol.175
, Issue.5
, pp. 3053-3059
-
-
Masteller, E.L.1
Warner, M.R.2
Tang, Q.3
-
75
-
-
2942642383
-
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
-
Q. Tang, K.J. Henriksen, and M. Bi In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes Journal of Experimental Medicine 199 2004 1455 1465
-
(2004)
Journal of Experimental Medicine
, vol.199
, pp. 1455-1465
-
-
Tang, Q.1
Henriksen, K.J.2
Bi, M.3
-
76
-
-
58849112222
-
Cutting edge: Antigen-specific TGF beta-induced regulatory T cells suppress Th17-mediated autoimmune disease
-
E.N. Huter, G.H. Stummvoll, and R.J. DiPaolo Cutting edge: antigen-specific TGF beta-induced regulatory T cells suppress Th17-mediated autoimmune disease J Immunol 181 12 2008 8209 8213
-
(2008)
J Immunol
, vol.181
, Issue.12
, pp. 8209-8213
-
-
Huter, E.N.1
Stummvoll, G.H.2
Dipaolo, R.J.3
-
79
-
-
63849112500
-
The role of indoleamine 2,3-dioxygenase in the induction of immune tolerance: Focus on hematology
-
A. Curti, S. Trabanelli, and V. Salvestrini The role of indoleamine 2,3-dioxygenase in the induction of immune tolerance: focus on hematology Blood 113 11 2009 2394 2401
-
(2009)
Blood
, vol.113
, Issue.11
, pp. 2394-2401
-
-
Curti, A.1
Trabanelli, S.2
Salvestrini, V.3
-
80
-
-
65649087461
-
Human adipose-derived mesenchymal stem cells reduce inflammatory and T-cell responses and induce regulatory T cells in vitro in rheumatoid arthritis
-
E. Gonzalez-Rey, M.A. Gonzalez, and N. Varela Human adipose-derived mesenchymal stem cells reduce inflammatory and T-cell responses and induce regulatory T cells in vitro in rheumatoid arthritis Ann Rheum Dis 2009
-
(2009)
Ann Rheum Dis
-
-
Gonzalez-Rey, E.1
Gonzalez, M.A.2
Varela, N.3
-
81
-
-
65249161683
-
Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells
-
M.A. Gonzalez, E. Gonzalez-Rey, and L. Rico Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells Arthritis Rheum 60 4 2009 1006 1019
-
(2009)
Arthritis Rheum
, vol.60
, Issue.4
, pp. 1006-1019
-
-
Gonzalez, M.A.1
Gonzalez-Rey, E.2
Rico, L.3
-
82
-
-
43049103438
-
Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: A phase II study
-
K. Le Blanc, F. Frassoni, and L. Ball Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study Lancet 371 9624 2008 1579 1586
-
(2008)
Lancet
, vol.371
, Issue.9624
, pp. 1579-1586
-
-
Le Blanc, K.1
Frassoni, F.2
Ball, L.3
-
83
-
-
73949086464
-
Mesenchymal stem cells in regenerative medicine: Opportunities and challenges for articular cartilage and intervertebral disc tissue engineering
-
S.M. Richardson, J.A. Hoyland, and R. Mobasheri Mesenchymal stem cells in regenerative medicine: opportunities and challenges for articular cartilage and intervertebral disc tissue engineering Journal of Cell Physiology 222 2010 23 32
-
(2010)
Journal of Cell Physiology
, vol.222
, pp. 23-32
-
-
Richardson, S.M.1
Hoyland, J.A.2
Mobasheri, R.3
-
84
-
-
34248512220
-
Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis: A double-blind, randomized, placebo-controlled trial
-
H. van Dongen, J. van Aken, and L.R. Lard Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis: a double-blind, randomized, placebo-controlled trial Arthritis Rheum 56 5 2007 1424 1432
-
(2007)
Arthritis Rheum
, vol.56
, Issue.5
, pp. 1424-1432
-
-
Van Dongen, H.1
Van Aken, J.2
Lard, L.R.3
-
85
-
-
77949442819
-
The impact of T-cell co-stimulation modulation in patients with undifferentiated inflammatory arthritis or very early rheumatoid arthritis: A clinical and imaging study of abatacept
-
P. Emery, P. Durez, and M. Dougados The impact of T-cell co-stimulation modulation in patients with undifferentiated inflammatory arthritis or very early rheumatoid arthritis: a clinical and imaging study of abatacept Ann Rheum Dis 69 3 2010 p510 p516
-
(2010)
Ann Rheum Dis
, vol.69
, Issue.3
-
-
Emery, P.1
Durez, P.2
Dougados, M.3
-
86
-
-
19944431840
-
Very early treatment with infliximab in addition to methotrexate in early, poor-prognosis rheumatoid arthritis reduces magnetic resonance imaging evidence of synovitis and damage, with sustained benefit after infliximab withdrawal: Results from a twelve-month randomised, double-blind, placebo-controlled trial
-
M.A. Quinn, P.G. Conaghan, and P.J. O'Connor Very early treatment with infliximab in addition to methotrexate in early, poor-prognosis rheumatoid arthritis reduces magnetic resonance imaging evidence of synovitis and damage, with sustained benefit after infliximab withdrawal: results from a twelve-month randomised, double-blind, placebo-controlled trial Arth Rheum 52 2005 27 35
-
(2005)
Arth Rheum
, vol.52
, pp. 27-35
-
-
Quinn, M.A.1
Conaghan, P.G.2
O'Connor, P.J.3
-
87
-
-
33846446041
-
Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta
-
S. Nadkarni, C. Mauri, and M.R. Ehrenstein Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta J Exp Med 204 1 2007 33 39
-
(2007)
J Exp Med
, vol.204
, Issue.1
, pp. 33-39
-
-
Nadkarni, S.1
Mauri, C.2
Ehrenstein, M.R.3
|