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Volumn 38, Issue 15, 2010, Pages 5036-5046

The catalytic function of the Rev1 dCMP transferase is required in a lesion-specific manner for translesion synthesis and base damage-induced mutagenesis

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ASPARTIC ACID; DNA; DNA POLYMERASE REV1; GLUTAMIC ACID; 1,N(6)-ETHENOADENINE; ADENINE; DNA ADDUCT; DNA DIRECTED DNA POLYMERASE; DNA POLYMERASE ZETA; NUCLEOTIDYLTRANSFERASE; REV1 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN;

EID: 77956102849     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq225     Document Type: Article
Times cited : (36)

References (47)
  • 1
    • 0141831006 scopus 로고    scopus 로고
    • Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation
    • Stelter,P. and Ulrich,H.D. (2003) Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation. Nature, 425, 188-191.
    • (2003) Nature , vol.425 , pp. 188-191
    • Stelter, P.1    Ulrich, H.D.2
  • 2
    • 77956116645 scopus 로고    scopus 로고
    • Mechanism of bypass polymerases in eukaryotes
    • Siede,W., Kow,Y.W. and Doetsch,P.W. (eds), Taylor & Francis Group, New York, NY
    • Wang,Z. (2006) Mechanism of bypass polymerases in eukaryotes. In Siede,W., Kow,Y.W. and Doetsch,P.W. (eds), DNA Damage Recognition. Taylor & Francis Group, New York, NY, pp. 507-528.
    • (2006) DNA Damage Recognition , pp. 507-528
    • Wang, Z.1
  • 3
    • 27844460203 scopus 로고    scopus 로고
    • The p-benzoquinone DNA adducts derived from benzene are highly mutagenic
    • Xie,Z., Zhang,Y., Guliaev,A.B., Shen,H., Hang,B., Singer,B. and Wang,Z. (2005) The p-benzoquinone DNA adducts derived from benzene are highly mutagenic. DNA Repair, 4, 1399-1409.
    • (2005) DNA Repair , vol.4 , pp. 1399-1409
    • Xie, Z.1    Zhang, Y.2    Guliaev, A.B.3    Shen, H.4    Hang, B.5    Singer, B.6    Wang, Z.7
  • 4
    • 0141567937 scopus 로고    scopus 로고
    • Mutagenesis of benzo[a]pyrene diol epoxide in yeast: requirement for DNA polymerase ζ and involvement of DNA polymerase Z
    • Xie,Z., Braithwaite,E., Guo,D., Zhao,B., Geacintov,N.E. and Wang,Z. (2003) Mutagenesis of benzo[a]pyrene diol epoxide in yeast: requirement for DNA polymerase ζ and involvement of DNA polymerase Z. Biochemistry, 42, 11253-11262.
    • (2003) Biochemistry , vol.42 , pp. 11253-11262
    • Xie, Z.1    Braithwaite, E.2    Guo, D.3    Zhao, B.4    Geacintov, N.E.5    Wang, Z.6
  • 6
    • 15544386652 scopus 로고    scopus 로고
    • The relative roles in vivo of Saccharomyces cerevisiae Pol Z, Pol z, Rev1 protein and Pol32 in the bypass and mutation induction of an abasic site T-T (6-4) photoadduct and T-T cissyn cyclobutane dimer
    • Gibbs,P.E., McDonald,J., Woodgate,R. and Lawrence,C.W. (2005) The relative roles in vivo of Saccharomyces cerevisiae Pol Z, Pol z, Rev1 protein and Pol32 in the bypass and mutation induction of an abasic site, T-T (6-4) photoadduct and T-T cissyn cyclobutane dimer. Genetics, 169, 575-582.
    • (2005) Genetics , vol.169 , pp. 575-582
    • Gibbs, P.E.1    McDonald, J.2    Woodgate, R.3    Lawrence, C.W.4
  • 7
    • 32644435469 scopus 로고    scopus 로고
    • PolZ Polz and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells
    • Zhao,B., Wang,J., Geacintov,N.E. and Wang,Z. (2006) PolZ, Polz and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells. Nucleic Acids Res., 34, 417-425.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 417-425
    • Zhao, B.1    Wang, J.2    Geacintov, N.E.3    Wang, Z.4
  • 8
    • 0032190633 scopus 로고    scopus 로고
    • Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites
    • Johnson,R.E., Torres-Ramos,C.A., Izumi,T., Mitra,S., Prakash,S. and Prakash,L. (1998) Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites. Genes. Dev., 12, 3137-3143.
    • (1998) Genes. Dev. , vol.12 , pp. 3137-3143
    • Johnson, R.E.1    Torres-Ramos, C.A.2    Izumi, T.3    Mitra, S.4    Prakash, S.5    Prakash, L.6
  • 9
    • 0021869226 scopus 로고
    • REV7, a new gene concerned with UV mutagenesis in yeast
    • Lawrence,C.W., Das,G. and Christensen,R.B. (1985) REV7, a new gene concerned with UV mutagenesis in yeast. Mol. Gen. Genet., 200, 80-85.
    • (1985) Mol. Gen. Genet. , vol.200 , pp. 80-85
    • Lawrence, C.W.1    Das, G.2    Christensen, R.B.3
  • 10
    • 0024526246 scopus 로고
    • The REV1 gene of Saccharomyces cerevisiae: isolation, sequence, and functional analysis
    • Larimer,F.W., Perry,J.R. and Hardigree,A.A. (1989) The REV1 gene of Saccharomyces cerevisiae: isolation, sequence, and functional analysis. J. Bacteriol., 171, 230-237.
    • (1989) J. Bacteriol. , vol.171 , pp. 230-237
    • Larimer, F.W.1    Perry, J.R.2    Hardigree, A.A.3
  • 11
    • 0024461293 scopus 로고
    • REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase
    • Morrison,A., Christensen,R.B., Alley,J., Beck,A.K., Bernstine,E.G., Lemontt,J.F. and Lawrence,C.W. (1989) REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase. J. Bacteriol., 171, 5659-5667.
    • (1989) J. Bacteriol. , vol.171 , pp. 5659-5667
    • Morrison, A.1    Christensen, R.B.2    Alley, J.3    Beck, A.K.4    Bernstine, E.G.5    Lemontt, J.F.6    Lawrence, C.W.7
  • 12
    • 0030443024 scopus 로고    scopus 로고
    • DNA polymerase z and the control of DNA damage induced mutagenesis in eukaryotes
    • Lawrence,C.W. and Hinkle,D.C. (1996) DNA polymerase z and the control of DNA damage induced mutagenesis in eukaryotes. Cancer Surveys, 28, 21-31.
    • (1996) Cancer Surveys , vol.28 , pp. 21-31
    • Lawrence, C.W.1    Hinkle, D.C.2
  • 13
    • 0034676229 scopus 로고    scopus 로고
    • Alteration of ultraviolet-induced mutagenesis in yeast through molecular modulation of the REV3 and REV7 gene expression
    • Rajpal,D.K., Wu,X. and Wang,Z. (2000) Alteration of ultraviolet-induced mutagenesis in yeast through molecular modulation of the REV3 and REV7 gene expression. Mutat. Res., 461, 133-143.
    • (2000) Mutat. Res. , vol.461 , pp. 133-143
    • Rajpal, D.K.1    Wu, X.2    Wang, Z.3
  • 14
    • 0032499748 scopus 로고    scopus 로고
    • A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase ζ
    • Gibbs,P.E., McGregor,W.G., Maher,V.M., Nisson,P. and Lawrence,C.W. (1998) A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase ζ. Proc. Natl Acad. Sci. USA, 95, 6876-6880.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 6876-6880
    • Gibbs, P.E.1    McGregor, W.G.2    Maher, V.M.3    Nisson, P.4    Lawrence, C.W.5
  • 15
    • 0034636106 scopus 로고    scopus 로고
    • The function of the human homolog of saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light
    • Gibbs,P.E., Wang,X.D., Li,Z., McManus,T.P., McGregor,W.G., Lawrence,C.W. and Maher,V.M. (2000) The function of the human homolog of saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light. Proc. Natl Acad. Sci. USA, 97, 4186-4191.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 4186-4191
    • Gibbs, P.E.1    Wang, X.D.2    Li, Z.3    McManus, T.P.4    McGregor, W.G.5    Lawrence, C.W.6    Maher, V.M.7
  • 16
    • 10244232940 scopus 로고    scopus 로고
    • REV1 accumulates in DNA damage-induced nuclear foci in human cells and is implicated in mutagenesis by benzo[a]pyrenediolepoxide
    • Mukhopadhyay,S., Clark,D.R., Watson,N.B., Zacharias,W. and McGregor,W.G. (2004) REV1 accumulates in DNA damage-induced nuclear foci in human cells and is implicated in mutagenesis by benzo[a]pyrenediolepoxide. Nucleic Acids Res., 32, 5820-5826.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 5820-5826
    • Mukhopadhyay, S.1    Clark, D.R.2    Watson, N.B.3    Zacharias, W.4    McGregor, W.G.5
  • 18
    • 24944540730 scopus 로고    scopus 로고
    • REV1 mediated mutagenesis in base excision repair deficient mouse fibroblast
    • Poltoratsky,V., Horton,J.K., Prasad,R. and Wilson,S.H. (2005) REV1 mediated mutagenesis in base excision repair deficient mouse fibroblast. DNA Repair, 4, 1182-1188.
    • (2005) DNA Repair , vol.4 , pp. 1182-1188
    • Poltoratsky, V.1    Horton, J.K.2    Prasad, R.3    Wilson, S.H.4
  • 19
    • 0029952294 scopus 로고    scopus 로고
    • Thymine-thymine dimer bypass by yeast DNA polymerase ζ
    • Nelson,J.R., Lawrence,C.W. and Hinkle,D.C. (1996) Thymine-thymine dimer bypass by yeast DNA polymerase ζ. Science, 272, 1646-1649.
    • (1996) Science , vol.272 , pp. 1646-1649
    • Nelson, J.R.1    Lawrence, C.W.2    Hinkle, D.C.3
  • 21
    • 0033548231 scopus 로고    scopus 로고
    • Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase
    • Johnson,R.E., Prakash,S. and Prakash,L. (1999) Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, PolZ. Science, 283, 1001-1004.
    • (1999) PolZ. Science , vol.283 , pp. 1001-1004
    • Johnson, R.E.1    Prakash, S.2    Prakash, L.3
  • 22
    • 0033564917 scopus 로고    scopus 로고
    • Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity
    • Masutani,C., Araki,M., Yamada,A., Kusumoto,R., Nogimori,T., Maekawa,T., Iwai,S. and Hanaoka,F. (1999) Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity. EMBO J., 18, 3491-3501.
    • (1999) EMBO J. , vol.18 , pp. 3491-3501
    • Masutani, C.1    Araki, M.2    Yamada, A.3    Kusumoto, R.4    Nogimori, T.5    Maekawa, T.6    Iwai, S.7    Hanaoka, F.8
  • 23
    • 0029787108 scopus 로고    scopus 로고
    • Deoxycytidyl transferase activity of yeast REV1 protein
    • Nelson,J.R., Lawrence,C.W. and Hinkle,D.C. (1996) Deoxycytidyl transferase activity of yeast REV1 protein. Nature, 382, 729-731.
    • (1996) Nature , vol.382 , pp. 729-731
    • Nelson, J.R.1    Lawrence, C.W.2    Hinkle, D.C.3
  • 24
    • 0033571521 scopus 로고    scopus 로고
    • The human REV1 gene codes for a DNA template-dependent dCMP transferase
    • Lin,W., Xin,H., Zhang,Y., Wu,X., Yuan,F. and Wang,Z. (1999) The human REV1 gene codes for a DNA template-dependent dCMP transferase. Nucleic Acids Res., 27, 4468-4475.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 4468-4475
    • Lin, W.1    Xin, H.2    Zhang, Y.3    Wu, X.4    Yuan, F.5    Wang, Z.6
  • 25
    • 0036529562 scopus 로고    scopus 로고
    • Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion
    • Zhang,Y., Wu,X., Rechkoblit,O., Geacintov,N.E., Taylor,J.S. and Wang,Z. (2002) Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion. Nucleic Acids Res., 30, 1630-1638.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 1630-1638
    • Zhang, Y.1    Wu, X.2    Rechkoblit, O.3    Geacintov, N.E.4    Taylor, J.S.5    Wang, Z.6
  • 26
    • 0037169495 scopus 로고    scopus 로고
    • Mechanisms of dCMP transferase reactions catalyzed by mouse Rev1 protein
    • Masuda,Y., Takahashi,M., Fukuda,S., Sumii,M. and Kamiya,K. (2002) Mechanisms of dCMP transferase reactions catalyzed by mouse Rev1 protein. J. Biol. Chem., 277, 3040-3046.
    • (2002) J. Biol. Chem. , vol.277 , pp. 3040-3046
    • Masuda, Y.1    Takahashi, M.2    Fukuda, S.3    Sumii, M.4    Kamiya, K.5
  • 27
    • 25844440534 scopus 로고    scopus 로고
    • Rev1 employs a novel mechanism of DNA synthesis using a protein template
    • Nair,D.T., Johnson,R.E., Prakash,L., Prakash,S. and Aggarwal,A.K. (2005) Rev1 employs a novel mechanism of DNA synthesis using a protein template. Science, 309, 2219-2222.
    • (2005) Science , vol.309 , pp. 2219-2222
    • Nair, D.T.1    Johnson, R.E.2    Prakash, L.3    Prakash, S.4    Aggarwal, A.K.5
  • 30
    • 0028216653 scopus 로고
    • Formation, detection, and role in carcinogenesis of ethenobases in DNA
    • Bartsch,H., Barbin,A., Marion,M.J., Nair,J. and Guichard,Y. (1994) Formation, detection, and role in carcinogenesis of ethenobases in DNA. Drug Metabolism Rev., 26, 349-371.
    • (1994) Drug Metabolism Rev , vol.26 , pp. 349-371
    • Bartsch, H.1    Barbin, A.2    Marion, M.J.3    Nair, J.4    Guichard, Y.5
  • 31
    • 0002530331 scopus 로고    scopus 로고
    • Etheno DNA-base adducts from endogenous reactive species
    • Nair,J., Barbin,A., Velic,I. and Bartsch,H. (1999) Etheno DNA-base adducts from endogenous reactive species. Mutat. Res., 424, 59-69.
    • (1999) Mutat. Res. , vol.424 , pp. 59-69
    • Nair, J.1    Barbin, A.2    Velic, I.3    Bartsch, H.4
  • 32
    • 0034556629 scopus 로고    scopus 로고
    • Error-prone lesion bypass by human DNA polymerase Z
    • Zhang,Y., Yuan,F., Wu,X., Talor,J.-S. and Wang,Z. (2000) Error-prone lesion bypass by human DNA polymerase Z. Nucleic Acids Res., 28, 4717-4724.
    • (2000) Nucleic Acids Res , vol.28 , pp. 4717-4724
    • Zhang, Y.1    Yuan, F.2    Wu, X.3    Talor, J.-S.4    Wang, Z.5
  • 33
    • 0033830464 scopus 로고    scopus 로고
    • Preferential incorporation of G opposite template T by the low fidelity human DNA polymerase η
    • Zhang,Y., Yuan,F., Wu,X. and Wang,Z. (2000) Preferential incorporation of G opposite template T by the low fidelity human DNA polymerase (. Mol. Cell. Biol., 20, 7099-7108.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7099-7108
    • Zhang, Y.1    Yuan, F.2    Wu, X.3    Wang, Z.4
  • 35
    • 2342635739 scopus 로고    scopus 로고
    • Translesion synthesis of acetylaminofluorene-dG adducts by DNA polymerase ζ is stimulated by yeast Rev1 protein
    • Guo,D., Xie,Z., Shen,H., Zhao,B. and Wang,Z. (2004) Translesion synthesis of acetylaminofluorene-dG adducts by DNA polymerase ζ is stimulated by yeast Rev1 protein. Nucleic Acids Res., 32, 1122-1130.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 1122-1130
    • Guo, D.1    Xie, Z.2    Shen, H.3    Zhao, B.4    Wang, Z.5
  • 36
    • 3242794439 scopus 로고    scopus 로고
    • Role of DNA polymerase η in the bypass of abasic sites in yeast cells
    • Zhao,B., Xie,Z., Shen,H. and Wang,Z. (2004) Role of DNA polymerase η in the bypass of abasic sites in yeast cells. Nucleic Acids Res., 32, 3984-3994.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 3984-3994
    • Zhao, B.1    Xie, Z.2    Shen, H.3    Wang, Z.4
  • 37
    • 0141567937 scopus 로고    scopus 로고
    • Mutagenesis of benzo[a]pyrene diol epoxide in yeast: Requirement for DNA polymerase ζ and involvement of DNA polymerase η
    • Xie,Z., Braithwaite,E., Guo,D., Bo,Z., Geacintov,N.E. and Wang,Z. (2003) Mutagenesis of benzo[a]pyrene diol epoxide in yeast: Requirement for DNA polymerase ζ and involvement of DNA polymerase η. Biochemistry, 42, 11253-11262.
    • (2003) Biochemistry , vol.42 , pp. 11253-11262
    • Xie, Z.1    Braithwaite, E.2    Guo, D.3    Bo, Z.4    Geacintov, N.E.5    Wang, Z.6
  • 38
    • 0028834955 scopus 로고
    • Gel fidelity assay measuring nucleotide misinsertion, exonucleolytic proofreading, and lesion bypass efficiencies
    • Creighton,S., Bloom,L.B. and Goodman,M.F. (1995) Gel fidelity assay measuring nucleotide misinsertion, exonucleolytic proofreading, and lesion bypass efficiencies. Methods Enzymol., 262, 232-256.
    • (1995) Methods Enzymol. , vol.262 , pp. 232-256
    • Creighton, S.1    Bloom, L.B.2    Goodman, M.F.3
  • 40
    • 0025974216 scopus 로고
    • High-efficiency transformation of yeast by electroporation
    • Becker,D.M. and Guarente,L. (1991) High-efficiency transformation of yeast by electroporation. Methods Enzymol., 194, 182-187.
    • (1991) Methods Enzymol. , vol.194 , pp. 182-187
    • Becker, D.M.1    Guarente, L.2
  • 42
    • 0029665327 scopus 로고    scopus 로고
    • 6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells
    • 6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells. Biochemistry, 35, 11487-11492.
    • (1996) Biochemistry , vol.35 , pp. 11487-11492
    • Pandya, G.A.1    Moriya, M.2
  • 46
    • 33748344714 scopus 로고    scopus 로고
    • Chronic inflammation and oxidative stress in the genesis and perpetuation of cancer: role of lipid peroxidation, DNA damage, and repair
    • Bartsch,H. and Nair,J. (2006) Chronic inflammation and oxidative stress in the genesis and perpetuation of cancer: role of lipid peroxidation, DNA damage, and repair. Langenbeck's Archives of Surgery / Deutsche Gesellschaft fur Chirurgie, 391, 499-510.
    • (2006) Langenbeck's Archives of Surgery / Deutsche Gesellschaft fur Chirurgie , vol.391 , pp. 499-510
    • Bartsch, H.1    Nair, J.2
  • 47
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens,L.M. and Werb,Z. (2002) Inflammation and cancer. Nature, 420, 860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.