-
1
-
-
0036841697
-
Hepatocellular carcinoma: An epidemiologic view
-
El-Serag HB. Hepatocellular carcinoma: an epidemiologic view. J Clin Gastroenterol 2002;35:S72-S78.
-
(2002)
J Clin Gastroenterol
, vol.35
-
-
El-Serag, H.B.1
-
2
-
-
0022474895
-
Emergence of malignant lesions within an adenomatous hyperplastic nodule in a cirrhotic liver. Observations in five cases
-
Arakawa M, Kage M, Sugihara S, et al. Emergence of malignant lesions within an adenomatous hyperplastic nodule in a cirrhotic liver. Observations in five cases. Gastroenterology 1986;91:198-208.
-
(1986)
Gastroenterology
, vol.91
, pp. 198-208
-
-
Arakawa, M.1
Kage, M.2
Sugihara, S.3
-
4
-
-
0022297755
-
Inhibitory effect of transforming growth factor-beta on DNA synthesis of adult rat hepatocytes in primary culture
-
Nakamura T, Tomita Y, Hirai R, et al. Inhibitory effect of transforming growth factor-beta on DNA synthesis of adult rat hepatocytes in primary culture. Biochem Biophys Res Commun 1985;133:1042-1050.
-
(1985)
Biochem Biophys Res Commun
, vol.133
, pp. 1042-1050
-
-
Nakamura, T.1
Tomita, Y.2
Hirai, R.3
-
5
-
-
0022569829
-
Inhibition of DNA synthesis in rat hepatocytes by platelet-derived type beta transforming growth factor
-
Carr BI, Hayashi I, Branum EL, et al. Inhibition of DNA synthesis in rat hepatocytes by platelet-derived type beta transforming growth factor. Cancer Res 1986;46:2330-2334.
-
(1986)
Cancer Res
, vol.46
, pp. 2330-2334
-
-
Carr, B.I.1
Hayashi, I.2
Branum, E.L.3
-
6
-
-
0034644472
-
TGFb signaling in growth control, cancer, and heritable disorders
-
Massague J, Blain SW, Lo RS. TGFb signaling in growth control, cancer, and heritable disorders. Cell 2000;103:295-309.
-
(2000)
Cell
, vol.103
, pp. 295-309
-
-
Massague, J.1
Blain, S.W.2
Lo, R.S.3
-
7
-
-
0034785348
-
TGF-b signaling in tumor suppression and cancer progression
-
Derynck R, Akhurst RJ, Balmain A. TGF-b signaling in tumor suppression and cancer progression. Nat Genet 2001;29:117-129.
-
(2001)
Nat Genet
, vol.29
, pp. 117-129
-
-
Derynck, R.1
Akhurst, R.J.2
Balmain, A.3
-
8
-
-
0242499448
-
Cytostatic and apoptotic actions of TGF-b in homeostasis and cancer
-
Siegel PM, Massague J. Cytostatic and apoptotic actions of TGF-b in homeostasis and cancer. Nat Rev Cancer 2003;3:807-821.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 807-821
-
-
Siegel, P.M.1
Massague, J.2
-
9
-
-
0029066689
-
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
-
Markowitz S, Wang J, Myeroff L, et al. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science 1995;268:1336-1338.
-
(1995)
Science
, vol.268
, pp. 1336-1338
-
-
Markowitz, S.1
Wang, J.2
Myeroff, L.3
-
10
-
-
0028785602
-
A transforming growth factor beta receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability
-
Myeroff LL, Parsons R, Kim SJ, et al. A transforming growth factor beta receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability. Cancer Res 1995;55:5545-5547.
-
(1995)
Cancer Res
, vol.55
, pp. 5545-5547
-
-
Myeroff, L.L.1
Parsons, R.2
Kim, S.J.3
-
11
-
-
0028556486
-
Genetic changes in the transforming growth factor beta (TGF-beta) type II receptor gene in human gastric cancer cells: Correlation with sensitivity to growth inhibition by TGF-beta
-
Park K, Kim SJ, Bang YJ, et al. Genetic changes in the transforming growth factor beta (TGF-beta) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-beta. Proc Natl Acad Sci USA 1994;91:8772-8776.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8772-8776
-
-
Park, K.1
Kim, S.J.2
Bang, Y.J.3
-
12
-
-
0031590968
-
Microsatellite instability and mutated type II transforming growth factor-beta receptor gene in gliomas
-
Izumoto S, Arita N, Ohnishi T, et al. Microsatellite instability and mutated type II transforming growth factor-beta receptor gene in gliomas. Cancer Lett 1997;112:251-256.
-
(1997)
Cancer Lett
, vol.112
, pp. 251-256
-
-
Izumoto, S.1
Arita, N.2
Ohnishi, T.3
-
13
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn SA, Schutte M, Hoque AT, et al. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 1996;271:350-353.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
-
14
-
-
0032622519
-
Mutation analysis of transforming growth factor beta type II receptor, Smad2, and Smad4 in hepatocellular carcinoma
-
Kawate S, Takenoshita S, Ohwada S, et al. Mutation analysis of transforming growth factor beta type II receptor, Smad2, and Smad4 in hepatocellular carcinoma. Int J Oncol 1999;14:127-131.
-
(1999)
Int J Oncol
, vol.14
, pp. 127-131
-
-
Kawate, S.1
Takenoshita, S.2
Ohwada, S.3
-
15
-
-
0033606964
-
Smad2 and Smad4 gene mutations in hepatocellular carcinoma
-
Yakicier MC, Irmak MB, Romano A, et al. Smad2 and Smad4 gene mutations in hepatocellular carcinoma. Oncogene 1999;18:4879-4883.
-
(1999)
Oncogene
, vol.18
, pp. 4879-4883
-
-
Yakicier, M.C.1
Irmak, M.B.2
Romano, A.3
-
16
-
-
0001939572
-
Hepatocellular carcinoma
-
Hamilton SR, Aaltonen LA (eds) IARC Press: Lyon
-
Hirohashi S, Ishak KG, Kojiro M, et al. Hepatocellular carcinoma. In: Hamilton SR, Aaltonen LA (eds). Tumours of the Digestive System. IARC Press: Lyon, 2000, pp 159-172.
-
(2000)
Tumours of the Digestive System
, pp. 159-172
-
-
Hirohashi, S.1
Ishak, K.G.2
Kojiro, M.3
-
17
-
-
85008135285
-
Establishment and characterization of human hepatocellular carcinoma cell line (KIM-1)
-
Murakami T. Establishment and characterization of human hepatocellular carcinoma cell line (KIM-1). Acta Hepatol Jpn 1984;25:532-539.
-
(1984)
Acta Hepatol Jpn
, vol.25
, pp. 532-539
-
-
Murakami, T.1
-
18
-
-
0023687856
-
A new human pleomorphic hepatocellular carcinoma cell line, KYN-2
-
Yano H, Maruiwa M, Murakami T, et al. A new human pleomorphic hepatocellular carcinoma cell line, KYN-2. Acta Pathol Jpn 1988;38:953-966.
-
(1988)
Acta Pathol Jpn
, vol.38
, pp. 953-966
-
-
Yano, H.1
Maruiwa, M.2
Murakami, T.3
-
19
-
-
0029975798
-
E-cadherin is involved in the intrahepatic metastasis of hepatocellular carcinoma
-
Osada T, Sakamoto M, Ino Y, et al. E-cadherin is involved in the intrahepatic metastasis of hepatocellular carcinoma. Hepatology 1996;24:1460-1467.
-
(1996)
Hepatology
, vol.24
, pp. 1460-1467
-
-
Osada, T.1
Sakamoto, M.2
Ino, Y.3
-
20
-
-
0032441150
-
Cluster analysis and display of genome-wide expression patterns
-
Eisen MB, Spellman PT, Brown PO, et al. Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci USA 1998;95:14863-14868.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14863-14868
-
-
Eisen, M.B.1
Spellman, P.T.2
Brown, P.O.3
-
21
-
-
0032870464
-
Cell motility mediated by rho and rho-associated protein kinase plays a critical role in intrahepatic metastasis of human hepatocellular carcinoma
-
Genda T, Sakamoto M, Ichida T, et al. Cell motility mediated by rho and rho-associated protein kinase plays a critical role in intrahepatic metastasis of human hepatocellular carcinoma. Hepatology 1999;30:1027-1036.
-
(1999)
Hepatology
, vol.30
, pp. 1027-1036
-
-
Genda, T.1
Sakamoto, M.2
Ichida, T.3
-
22
-
-
0032964644
-
Transforming growth factor betas and their signaling receptors in human hepatocellular carcinoma
-
Abou-Shady M, Baer HU, Friess H, et al. Transforming growth factor betas and their signaling receptors in human hepatocellular carcinoma. Am J Surg 1999;177:209-215.
-
(1999)
Am J Surg
, vol.177
, pp. 209-215
-
-
Abou-Shady, M.1
Baer, H.U.2
Friess, H.3
-
23
-
-
0030857813
-
Analysis of transforming growth factor (TGF)-alpha/epidermal growth factor receptor, hepatocyte growth Factor/c-met, TGF-beta receptor type II, and p53 expression in human hepatocellular carcinomas
-
Kiss A, Wang NJ, Xie JP, et al. Analysis of transforming growth factor (TGF)-alpha/epidermal growth factor receptor, hepatocyte growth Factor/c-met, TGF-beta receptor type II, and p53 expression in human hepatocellular carcinomas. Clin Cancer Res 1997;3:1059-1066.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 1059-1066
-
-
Kiss, A.1
Wang, N.J.2
Xie, J.P.3
-
24
-
-
18744395234
-
Altered expression of TGF-beta receptors in hepatocellular carcinoma-effects of a constitutively active TGF-beta type i receptor mutant
-
Musch A, Rabe C, Paik M, et al. Altered expression of TGF-beta receptors in hepatocellular carcinoma-effects of a constitutively active TGF-beta type I receptor mutant. Digestion 2005;71:78-91.
-
(2005)
Digestion
, vol.71
, pp. 78-91
-
-
Musch, A.1
Rabe, C.2
Paik, M.3
-
25
-
-
0037987704
-
Promoter methylation of TGFbeta receptor i and mutation of TGFbeta receptor II are frequent events in MSI sporadic gastric carcinomas
-
Pinto M, Oliveira C, Cirnes L, et al. Promoter methylation of TGFbeta receptor I and mutation of TGFbeta receptor II are frequent events in MSI sporadic gastric carcinomas. J Pathol 2003;200:32-38.
-
(2003)
J Pathol
, vol.200
, pp. 32-38
-
-
Pinto, M.1
Oliveira, C.2
Cirnes, L.3
-
26
-
-
1842479071
-
Defective expression of transforming growth factor beta receptor type II is associated with CpG methylated promoter in primary non-small cell lung cancer
-
Zhang HT, Chen XF, Wang MH, et al. Defective expression of transforming growth factor beta receptor type II is associated with CpG methylated promoter in primary non-small cell lung cancer. Clin Cancer Res 2004;10:2359-2367.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2359-2367
-
-
Zhang, H.T.1
Chen, X.F.2
Wang, M.H.3
-
27
-
-
20544440113
-
CpG methylation at promoter site-140 inactivates TGFbeta2 receptor gene in prostate cancer
-
Zhao H, Shiina H, Greene KL, et al. CpG methylation at promoter site-140 inactivates TGFbeta2 receptor gene in prostate cancer. Cancer 2005;104:44-52.
-
(2005)
Cancer
, vol.104
, pp. 44-52
-
-
Zhao, H.1
Shiina, H.2
Greene, K.L.3
-
28
-
-
0023121835
-
Hepatic resection for hepatocellular carcinoma. Clinical features and long-term prognosis
-
Nagao T, Inoue S, Goto S, et al. Hepatic resection for hepatocellular carcinoma. Clinical features and long-term prognosis. Ann Surg 1987;205:33-40.
-
(1987)
Ann Surg
, vol.205
, pp. 33-40
-
-
Nagao, T.1
Inoue, S.2
Goto, S.3
-
29
-
-
0025095330
-
Postoperative recurrence of hepatocellular carcinoma
-
Nagao T, Inoue S, Yoshimi F, et al. Postoperative recurrence of hepatocellular carcinoma. Ann Surg 1990;211:28-33.
-
(1990)
Ann Surg
, vol.211
, pp. 28-33
-
-
Nagao, T.1
Inoue, S.2
Yoshimi, F.3
-
30
-
-
0026665936
-
Do the tumor cells of hepatocellular carcinomas dislodge into the portal venous stream during hepatic resection?
-
Yamanaka N, Okamoto E, Fujihara S, et al. Do the tumor cells of hepatocellular carcinomas dislodge into the portal venous stream during hepatic resection? Cancer 1992;70:2263-2267.
-
(1992)
Cancer
, vol.70
, pp. 2263-2267
-
-
Yamanaka, N.1
Okamoto, E.2
Fujihara, S.3
-
31
-
-
0037093274
-
Critical involvement of the phosphatidylinositol 3-kinase/Akt pathway in anchorage-independent growth and hematogeneous intrahepatic metastasis of liver cancer
-
Nakanishi K, Sakamoto M, Yasuda J, et al. Critical involvement of the phosphatidylinositol 3-kinase/Akt pathway in anchorage-independent growth and hematogeneous intrahepatic metastasis of liver cancer. Cancer Res 2002;62:2971-2975.
-
(2002)
Cancer Res
, vol.62
, pp. 2971-2975
-
-
Nakanishi, K.1
Sakamoto, M.2
Yasuda, J.3
-
32
-
-
4644271628
-
Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma
-
Chuma M, Sakamoto M, Yasuda J, et al. Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma. J Hepatol 2004;41:629-636.
-
(2004)
J Hepatol
, vol.41
, pp. 629-636
-
-
Chuma, M.1
Sakamoto, M.2
Yasuda, J.3
-
33
-
-
70350059078
-
Inhibition of transforming growth factor beta receptor i kinase blocks hepatocellular carcinoma growth through neo-angiogenesis regulation
-
Mazzocca A, Fransvea E, Lavezzari G, et al. Inhibition of transforming growth factor beta receptor I kinase blocks hepatocellular carcinoma growth through neo-angiogenesis regulation. Hepatology 2009;50:1140-1151.
-
(2009)
Hepatology
, vol.50
, pp. 1140-1151
-
-
Mazzocca, A.1
Fransvea, E.2
Lavezzari, G.3
-
34
-
-
75449092617
-
Down-regulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumor-stroma cross-talk and tumor progression in hepatocellular carcinoma
-
Mazzocca A, Fransvea E, Dituri F, et al. Down-regulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumor-stroma cross-talk and tumor progression in hepatocellular carcinoma. Hepatology 2010;51:523-534.
-
(2010)
Hepatology
, vol.51
, pp. 523-534
-
-
Mazzocca, A.1
Fransvea, E.2
Dituri, F.3
-
35
-
-
43949140575
-
Blocking transforming growth factor-beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells
-
Fransvea E, Angelotti U, Antonaci S, et al. Blocking transforming growth factor-beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells. Hepatology 2008;47:1557-1566.
-
(2008)
Hepatology
, vol.47
, pp. 1557-1566
-
-
Fransvea, E.1
Angelotti, U.2
Antonaci, S.3
-
36
-
-
46249085489
-
Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer
-
Coulouarn C, Factor VM, Thorgeirsson SS. Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer. Hepatology 2008;47:2059-2067.
-
(2008)
Hepatology
, vol.47
, pp. 2059-2067
-
-
Coulouarn, C.1
Factor, V.M.2
Thorgeirsson, S.S.3
-
37
-
-
34347232205
-
Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma
-
Matsuzaki K, Murata M, Yoshida K, et al. Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma. Hepatology 2007;46:48-57.
-
(2007)
Hepatology
, vol.46
, pp. 48-57
-
-
Matsuzaki, K.1
Murata, M.2
Yoshida, K.3
-
38
-
-
65449159717
-
Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B
-
Murata M, Matsuzaki K, Yoshida K, et al. Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B. Hepatology 2008;49:1203-1217.
-
(2008)
Hepatology
, vol.49
, pp. 1203-1217
-
-
Murata, M.1
Matsuzaki, K.2
Yoshida, K.3
|