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Volumn 349, Issue 2, 2006, Pages 799-803

Inhibition of the anti-adipogenic Hedgehog signaling pathway by cyclopamine does not trigger adipocyte differentiation

Author keywords

Adipocyte differentiation; Cyclopamine; Gli1; Hedgehog

Indexed keywords

ADIPSIN; CELL MARKER; CYCLOPAMINE; DEXAMETHASONE; INSULIN; ISOBUTYLMETHYLXANTHINE; PROTEIN AP2; PROTEIN C EBP ALPHA; PROTEIN PREF 1; SONIC HEDGEHOG PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 33748531312     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.08.112     Document Type: Article
Times cited : (17)

References (22)
  • 1
    • 0035936764 scopus 로고    scopus 로고
    • Obesity and the regulation of energy balance
    • Spiegelman B.M., and Flier J.S. Obesity and the regulation of energy balance. Cell 104 (2001) 531-543
    • (2001) Cell , vol.104 , pp. 531-543
    • Spiegelman, B.M.1    Flier, J.S.2
  • 2
    • 0033849777 scopus 로고    scopus 로고
    • Obesity and insulin resistance
    • Kahn B.B., and Flier J.S. Obesity and insulin resistance. J. Clin. Invest. 106 (2000) 473-481
    • (2000) J. Clin. Invest. , vol.106 , pp. 473-481
    • Kahn, B.B.1    Flier, J.S.2
  • 3
    • 0036381998 scopus 로고    scopus 로고
    • Adipose tissue as a buffer for daily lipid flux
    • Frayn K.N. Adipose tissue as a buffer for daily lipid flux. Diabetologia 45 (2002) 1201-1210
    • (2002) Diabetologia , vol.45 , pp. 1201-1210
    • Frayn, K.N.1
  • 6
    • 7244232742 scopus 로고    scopus 로고
    • Regulating the balance between peroxisome proliferator-activated receptor gamma and beta-catenin signaling during adipogenesis. A glycogen synthase kinase 3beta phosphorylation-defective mutant of beta-catenin inhibits expression of a subset of adipogenic genes
    • Liu J., and Farmer S.R. Regulating the balance between peroxisome proliferator-activated receptor gamma and beta-catenin signaling during adipogenesis. A glycogen synthase kinase 3beta phosphorylation-defective mutant of beta-catenin inhibits expression of a subset of adipogenic genes. J. Biol. Chem. 279 (2004) 45020-45027
    • (2004) J. Biol. Chem. , vol.279 , pp. 45020-45027
    • Liu, J.1    Farmer, S.R.2
  • 8
    • 0346996354 scopus 로고    scopus 로고
    • Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells
    • van der Horst G., Farih-Sips H., Lowik C.W., and Karperien M. Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells. Bone 33 (2003) 899-910
    • (2003) Bone , vol.33 , pp. 899-910
    • van der Horst, G.1    Farih-Sips, H.2    Lowik, C.W.3    Karperien, M.4
  • 9
    • 33645046358 scopus 로고    scopus 로고
    • Hedgehog signaling plays a conserved role in inhibiting fat formation
    • Suh J.M., Gao X., McKay J., McKay R., Salo Z., and Graff J.M. Hedgehog signaling plays a conserved role in inhibiting fat formation. Cell Metab. 3 (2006) 25-34
    • (2006) Cell Metab. , vol.3 , pp. 25-34
    • Suh, J.M.1    Gao, X.2    McKay, J.3    McKay, R.4    Salo, Z.5    Graff, J.M.6
  • 10
    • 32444449871 scopus 로고    scopus 로고
    • GLI transcription factors: mediators of oncogenic Hedgehog signalling
    • Kasper M., Regl G., Frischauf A.M., and Aberger F. GLI transcription factors: mediators of oncogenic Hedgehog signalling. Eur. J. Cancer 42 (2006) 437-445
    • (2006) Eur. J. Cancer , vol.42 , pp. 437-445
    • Kasper, M.1    Regl, G.2    Frischauf, A.M.3    Aberger, F.4
  • 11
    • 0036559186 scopus 로고    scopus 로고
    • Gli and hedgehog in cancer: tumours, embryos and stem cells
    • Ruiz i Altaba A., Sanchez P., and Dahmane N. Gli and hedgehog in cancer: tumours, embryos and stem cells. Nat. Rev. Cancer 2 (2002) 361-372
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 361-372
    • Ruiz i Altaba, A.1    Sanchez, P.2    Dahmane, N.3
  • 12
    • 13344283332 scopus 로고    scopus 로고
    • Hedgehog signaling: from the Drosophila cuticle to anti-cancer drugs
    • Briscoe J., and Therond P. Hedgehog signaling: from the Drosophila cuticle to anti-cancer drugs. Dev. Cell 8 (2005) 143-151
    • (2005) Dev. Cell , vol.8 , pp. 143-151
    • Briscoe, J.1    Therond, P.2
  • 13
    • 0030805592 scopus 로고    scopus 로고
    • Gli1 is a target of Sonic hedgehog that induces ventral neural tube development
    • Lee J., Platt K.A., Censullo P., and Ruiz i Altaba A. Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. Development 124 (1997) 2537-2552
    • (1997) Development , vol.124 , pp. 2537-2552
    • Lee, J.1    Platt, K.A.2    Censullo, P.3    Ruiz i Altaba, A.4
  • 14
    • 0030795109 scopus 로고    scopus 로고
    • Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1
    • Hynes M., Stone D.M., Dowd M., Pitts-Meek S., Goddard A., Gurney A., and Rosenthal A. Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1. Neuron 19 (1997) 15-26
    • (1997) Neuron , vol.19 , pp. 15-26
    • Hynes, M.1    Stone, D.M.2    Dowd, M.3    Pitts-Meek, S.4    Goddard, A.5    Gurney, A.6    Rosenthal, A.7
  • 16
    • 0036829397 scopus 로고    scopus 로고
    • Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
    • Chen J.K., Taipale J., Cooper M.K., and Beachy P.A. Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. Genes Dev. 16 (2002) 2743-2748
    • (2002) Genes Dev. , vol.16 , pp. 2743-2748
    • Chen, J.K.1    Taipale, J.2    Cooper, M.K.3    Beachy, P.A.4
  • 17
    • 23844542076 scopus 로고    scopus 로고
    • Hedgehog signaling pathway as a therapeutic target in breast cancer
    • Katano M. Hedgehog signaling pathway as a therapeutic target in breast cancer. Cancer Lett. 227 (2005) 99-104
    • (2005) Cancer Lett. , vol.227 , pp. 99-104
    • Katano, M.1
  • 18
    • 0345830390 scopus 로고    scopus 로고
    • Transdifferentiation of preadipose cells into smooth muscle-like cells: role of aortic carboxypeptidase-like protein
    • Abderrahim-Ferkoune A., Bezy O., Astri-Roques S., Elabd C., Ailhaud G., and Amri E.Z. Transdifferentiation of preadipose cells into smooth muscle-like cells: role of aortic carboxypeptidase-like protein. Exp. Cell Res. 293 (2004) 219-228
    • (2004) Exp. Cell Res. , vol.293 , pp. 219-228
    • Abderrahim-Ferkoune, A.1    Bezy, O.2    Astri-Roques, S.3    Elabd, C.4    Ailhaud, G.5    Amri, E.Z.6
  • 19
    • 2642515832 scopus 로고    scopus 로고
    • New insights into inhibitors of adipogenesis
    • Harp J.B. New insights into inhibitors of adipogenesis. Curr. Opin. Lipidol. 15 (2004) 303-307
    • (2004) Curr. Opin. Lipidol. , vol.15 , pp. 303-307
    • Harp, J.B.1
  • 20
    • 0033019684 scopus 로고    scopus 로고
    • Adipocyte differentiation is modulated by secreted delta-like (dlk) variants and requires the expression of membrane-associated dlk
    • Garces C., Ruiz-Hidalgo M.J., Bonvini E., Goldstein J., and Laborda J. Adipocyte differentiation is modulated by secreted delta-like (dlk) variants and requires the expression of membrane-associated dlk. Differentiation 64 (1999) 103-114
    • (1999) Differentiation , vol.64 , pp. 103-114
    • Garces, C.1    Ruiz-Hidalgo, M.J.2    Bonvini, E.3    Goldstein, J.4    Laborda, J.5
  • 21
    • 0035577854 scopus 로고    scopus 로고
    • Hedgehog signaling in animal development: paradigms and principles
    • Ingham P.W., and McMahon A.P. Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 15 (2001) 3059-3087
    • (2001) Genes Dev. , vol.15 , pp. 3059-3087
    • Ingham, P.W.1    McMahon, A.P.2
  • 22
    • 1842611651 scopus 로고    scopus 로고
    • Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton
    • Long F., Chung U.I., Ohba S., McMahon J., Kronenberg H.M., and McMahon A.P. Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development 131 (2004) 1309-1318
    • (2004) Development , vol.131 , pp. 1309-1318
    • Long, F.1    Chung, U.I.2    Ohba, S.3    McMahon, J.4    Kronenberg, H.M.5    McMahon, A.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.