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Volumn 16, Issue 8, 2010, Pages 2627-2639

ShRNA-mediated decreases in c-met levels affect the differentiation potential of human mesenchymal stem cells and reduce their capacity for tissue repair

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CELL CULTURE; HEMODYNAMICS; RESTORATION; SIGNALING;

EID: 77956072110     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2009.0363     Document Type: Article
Times cited : (8)

References (63)
  • 5
    • 55049084643 scopus 로고    scopus 로고
    • Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells
    • Rosova, I., Dao, M., Capoccia, B., Link, D., and Nolta, J.A. Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells. Stem Cells 26, 2173, 2008.
    • (2008) Stem Cells , vol.26 , pp. 2173
    • Rosova, I.1    Dao, M.2    Capoccia, B.3    Link, D.4    Nolta, J.A.5
  • 7
    • 1642373909 scopus 로고    scopus 로고
    • Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms
    • Kinnaird, T., Stabile, E., Burnett, M.S., Lee, C.W., Barr, S., Fuchs, S., and Epstein, S.E. Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms. Circ Res 94, 678, 2004.
    • (2004) Circ Res , vol.94 , pp. 678
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3    Lee, C.W.4    Barr, S.5    Fuchs, S.6    Epstein, S.E.7
  • 8
    • 0032719093 scopus 로고    scopus 로고
    • Sequential changes of hepatocyte growth factor in the serum and enhanced c-Met expression in the myocardium in acute myocardial infarction
    • Sato, T., Fujieda, H., Murao, S., Sato, H., Takeuchi, T., and Ohtsuki, Y. Sequential changes of hepatocyte growth factor in the serum and enhanced c-Met expression in the myocardium in acute myocardial infarction. Jpn Circ J 63, 906, 1999.
    • (1999) Jpn Circ J , vol.63 , pp. 906
    • Sato, T.1    Fujieda, H.2    Murao, S.3    Sato, H.4    Takeuchi, T.5    Ohtsuki, Y.6
  • 9
    • 0021285134 scopus 로고
    • Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats
    • Nakamura, T., Nawa, K., and Ichihara, A. Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats. Biochem Biophys Res Commun 122, 1450, 1984.
    • (1984) Biochem Biophys Res Commun , vol.122 , pp. 1450
    • Nakamura, T.1    Nawa, K.2    Ichihara, A.3
  • 10
    • 0033761488 scopus 로고    scopus 로고
    • The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase
    • Maroun, C.R., Naujokas, M.A., Holgado-Madruga, M., Wong, A.J., and Park, M. The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase. Mol Cell Biol 20, 8513, 2000.
    • (2000) Mol Cell Biol , vol.20 , pp. 8513
    • Maroun, C.R.1    Naujokas, M.A.2    Holgado-Madruga, M.3    Wong, A.J.4    Park, M.5
  • 11
    • 0036080893 scopus 로고    scopus 로고
    • Keratinocyte and hepatocyte growth factors in the lung: Roles in lung development, inflammation, and repair
    • Ware, L.B., and Matthay, M.A. Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair. Am J Physiol Lung Cell Mol Physiol 282, L924, 2002.
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.282
    • Ware, L.B.1    Matthay, M.A.2
  • 12
    • 2942583980 scopus 로고    scopus 로고
    • Functional expression of HGF and HGF receptor/c-met in adult human mesenchymal stem cells suggests a role in cell mobilization, tissue repair, and wound healing
    • Neuss, S., Becher, E., Woltje, M., Tietze, L., and Jahnen-Dechent, W. Functional expression of HGF and HGF receptor/c-met in adult human mesenchymal stem cells suggests a role in cell mobilization, tissue repair, and wound healing. Stem Cells 22, 405, 2004.
    • (2004) Stem Cells , vol.22 , pp. 405
    • Neuss, S.1    Becher, E.2    Woltje, M.3    Tietze, L.4    Jahnen-Dechent, W.5
  • 15
    • 0027437547 scopus 로고
    • Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development
    • Sonnenberg, E., Meyer, D., Weidner, K.M., and Birchmeier, C. Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development. J Cell Biol 123, 223, 1993.
    • (1993) J Cell Biol , vol.123 , pp. 223
    • Sonnenberg, E.1    Meyer, D.2    Weidner, K.M.3    Birchmeier, C.4
  • 16
    • 0025665128 scopus 로고
    • Expression of hepatocyte growth factor gene in endothelial and Kupffer cells of damaged rat livers, as revealed by in situ hybridization
    • Noji, S., Tashiro, K., Koyama, E., Nohno, T., Ohyama, K., Taniguchi, S., and Nakamura, T. Expression of hepatocyte growth factor gene in endothelial and Kupffer cells of damaged rat livers, as revealed by in situ hybridization. Biochem Biophys Res Commun 173, 42, 1990.
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 42
    • Noji, S.1    Tashiro, K.2    Koyama, E.3    Nohno, T.4    Ohyama, K.5    Taniguchi, S.6    Nakamura, T.7
  • 17
    • 0034035615 scopus 로고    scopus 로고
    • Gene therapy for liver cirrhosis
    • Fujimoto, J. Gene therapy for liver cirrhosis. J Gastroenterol Hepatol 15 Suppl, D33, 2000.
    • (2000) J Gastroenterol Hepatol , vol.15 , Issue.SUPPL. D33
    • Fujimoto, J.1
  • 18
    • 0033910377 scopus 로고    scopus 로고
    • Enhanced secretion of cardiac he-patocyte growth factor from an infarct region is associated with less severe ventricular enlargement and improved cardiac function
    • Yasuda, S., Goto, Y., Baba, T., Satoh, T., Sumida, H., Miya-zaki, S., and Nonogi, H. Enhanced secretion of cardiac he-patocyte growth factor from an infarct region is associated with less severe ventricular enlargement and improved cardiac function. J Am Coll Cardiol 36, 115, 2000.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 115
    • Yasuda, S.1    Goto, Y.2    Baba, T.3    Satoh, T.4    Sumida, H.5    Miya-Zaki, S.6    Nonogi, H.7
  • 19
    • 0032719093 scopus 로고    scopus 로고
    • Sequential changes of hepatocyte growth factor in the serum and enhanced c-Met expression inthe myocardium in acute myocardial infarction
    • Sato, T., Fujieda, H., Murao, S., Sato, H., Takeuchi, T., and Ohtsuki,Y.Sequential changes of hepatocyte growth factor in the serum and enhanced c-Met expression inthe myocardium in acute myocardial infarction. Jpn Circ J 63, 906, 1999.
    • (1999) Jpn Circ J , vol.63 , pp. 906
    • Sato, T.1    Fujieda, H.2    Murao, S.3    Sato, H.4    Takeuchi, T.5    Ohtsuki, Y.6
  • 20
    • 0033973604 scopus 로고    scopus 로고
    • HGF is an autocrine growth factor for skeletal muscle satellite cells in vitro
    • Sheehan, S.M., Tatsumi, R., Temm-Grove, C.J., and Allen, R.E. HGF is an autocrine growth factor for skeletal muscle satellite cells in vitro. Muscle Nerve 23, 239, 2000.
    • (2000) Muscle Nerve , vol.23 , pp. 239
    • Sheehan, S.M.1    Tatsumi, R.2    Temm-Grove, C.J.3    Allen, R.E.4
  • 21
    • 0027284446 scopus 로고
    • Hepatocyte growth factor stimulates growth of hematopoi-etic progenitor cells
    • Mizuno, K., Higuchi, O., Ihle, J.N., and Nakamura, T. Hepatocyte growth factor stimulates growth of hematopoi-etic progenitor cells. Biochem Biophys Res Commun 194, 178, 1993.
    • (1993) Biochem Biophys Res Commun , vol.194 , pp. 178
    • Mizuno, K.1    Higuchi, O.2    Ihle, J.N.3    Nakamura, T.4
  • 22
    • 0027948378 scopus 로고
    • Hepatocyte growth factor induces proliferation and differentiation of multipotent and erythroid hemopoietic progenitors
    • Galimi, F., Bagnara, G.P., Bonsi, L., Cottone, E., Follenzi, A., Simeone, A., and Comoglio, P.M. Hepatocyte growth factor induces proliferation and differentiation of multipotent and erythroid hemopoietic progenitors. J Cell Biol 127, 1743, 1994.
    • (1994) J Cell Biol , vol.127 , pp. 1743
    • Galimi, F.1    Bagnara, G.P.2    Bonsi, L.3    Cottone, E.4    Follenzi, A.5    Simeone, A.6    Comoglio, P.M.7
  • 23
    • 0029052214 scopus 로고
    • Hepatocyte growth factor as a hematopoietic regulator
    • Nishino, T., Hisha, H., Nishino, N., Adachi, M., and Ikehara, S. Hepatocyte growth factor as a hematopoietic regulator. Blood 85, 3093, 1995.
    • (1995) Blood , vol.85 , pp. 3093
    • Nishino, T.1    Hisha, H.2    Nishino, N.3    Adachi, M.4    Ikehara, S.5
  • 24
    • 0030474899 scopus 로고    scopus 로고
    • Role of hepatocyte growth factor in hemopoiesis
    • Ikehara, S. Role of hepatocyte growth factor in hemopoiesis. Leuk Lymphoma 23, 297, 1996.
    • (1996) Leuk Lymphoma , vol.23 , pp. 297
    • Ikehara, S.1
  • 30
    • 0036021052 scopus 로고    scopus 로고
    • Cooperative actions of he-patocyte growth factor and 1,25- dihydroxyvitamin D3 in osteoblastic differentiation of human vertebral bone marrow stromal cells
    • D'Ippolito, G., Schiller, P.C., Perez-stable, C., Balkan, W., Roos, B.A., and Howard, G.A. Cooperative actions of he-patocyte growth factor and 1,25-dihydroxyvitamin D3 in osteoblastic differentiation of human vertebral bone marrow stromal cells. Bone 31, 269, 2002.
    • (2002) Bone , vol.31 , pp. 269
    • D'Ippolito, G.1    Schiller, P.C.2    Perez-Stable, C.3    Balkan, W.4    Roos, B.A.5    Howard, G.A.6
  • 31
    • 10744233934 scopus 로고    scopus 로고
    • Treatment of myocardial ischemia with bone marrow-derived mesen-chymal stem cells overexpressing hepatocyte growth factor
    • Duan, H.F., Wu, C.T., Wu, D.L., Lu, Y., Liu, H.J., Ha, X.Q., Zhang, Q.W., Wang, H., Jia, X.X., and Wang, L.S. Treatment of myocardial ischemia with bone marrow-derived mesen-chymal stem cells overexpressing hepatocyte growth factor. Mol Ther 8, 467, 2003.
    • (2003) Mol Ther , vol.8 , pp. 467
    • Duan, H.F.1    Wu, C.T.2    Wu, D.L.3    Lu, Y.4    Liu, H.J.5    Ha, X.Q.6    Zhang, Q.W.7    Wang, H.8    Jia, X.X.9    Wang, L.S.10
  • 32
    • 37349023344 scopus 로고    scopus 로고
    • Suppression of hepatocyte growth factor production impairs the ability of adipose-derived stem cells to promote ischemic tissue revascularization
    • Cai, L., Johnstone, B.H., Cook, T.G., Liang, Z., Traktuev, D., Cornetta, K., Ingram, D.A., Rosen, E.D., and March, K.L. Suppression of hepatocyte growth factor production impairs the ability of adipose-derived stem cells to promote ischemic tissue revascularization. Stem Cells 25, 3234, 2007.
    • (2007) Stem Cells , vol.25 , pp. 3234
    • Cai, L.1    Johnstone, B.H.2    Cook, T.G.3    Liang, Z.4    Traktuev, D.5    Cornetta, K.6    Ingram, D.A.7    Rosen, E.D.8    March, K.L.9
  • 33
    • 0030713446 scopus 로고    scopus 로고
    • Activator-protein-1 binding potentiates the hypoxia-induciblefactor-1- mediated hypoxia-induced transcriptional activation of vascular-endothelial growth factor expression in C6 glioma cells
    • Damert, A., Ikeda, E., and Risau, W. Activator-protein-1 binding potentiates the hypoxia-induciblefactor-1-mediated hypoxia-induced transcriptional activation of vascular-endothelial growth factor expression in C6 glioma cells. Biochem J 327 (Pt 2), 419, 1997.
    • (1997) Biochem J , vol.327 , Issue.PART 2 , pp. 419
    • Damert, A.1    Ikeda, E.2    Risau, W.3
  • 35
    • 40949085086 scopus 로고    scopus 로고
    • Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis
    • Hu, X., Yu, S.P., Fraser, J.L., Lu, Z., Ogle, M.E., Wang, J.A., and Wei, L. Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis. J Thorac Cardiovasc Surg 135, 799, 2008.
    • (2008) J Thorac Cardiovasc Surg , vol.135 , pp. 799
    • Hu, X.1    Yu, S.P.2    Fraser, J.L.3    Lu, Z.4    Ogle, M.E.5    Wang, J.A.6    Wei, L.7
  • 36
    • 65849373134 scopus 로고    scopus 로고
    • Angiopoietin-1 protects mesenchymal stem cells against serum deprivation and hypoxia-induced apoptosis through the PI3K/Akt pathway
    • Liu, X.B., Jiang, J., Gui, C., Hu, X.Y., Xiang, M.X., and Wang, J.A. Angiopoietin-1 protects mesenchymal stem cells against serum deprivation and hypoxia-induced apoptosis through the PI3K/Akt pathway. Acta Pharmacol Sin 29, 815, 2008.
    • (2008) Acta Pharmacol Sin , vol.29 , pp. 815
    • Liu, X.B.1    Jiang, J.2    Gui, C.3    Hu, X.Y.4    Xiang, M.X.5    Wang, J.A.6
  • 37
    • 70450240736 scopus 로고    scopus 로고
    • Ischemic preconditioning augments survival of stem cells via miR-210 expression by targeting caspase-8-associated protein 2
    • Won Kim, H., Haider, H.K., Jiang, S., and Ashraf, M. Ischemic preconditioning augments survival of stem cells via miR-210 expression by targeting caspase-8-associated protein 2. J Biol Chem 284, 33161, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 33161
    • Won Kim, H.1    Haider, H.K.2    Jiang, S.3    Ashraf, M.4
  • 38
    • 84934439850 scopus 로고    scopus 로고
    • Analysis of receptor ty-rosine kinase internalization using flow cytometry
    • Li, N., Hill, K.S., and Elferink, L.A. Analysis of receptor ty-rosine kinase internalization using flow cytometry. Methods Mol Biol (Clifton, NJ) 457, 305, 2008.
    • (2008) Methods Mol Biol (Clifton, NJ) , vol.457 , pp. 305
    • Li, N.1    Hill, K.S.2    Elferink, L.A.3
  • 39
    • 0027218744 scopus 로고
    • Internalization and degradation of hepatocyte growth factor in hepatocytes with down-regulation of the receptor/c-Met
    • Naka, D., Shimomura, T., Yoshiyama, Y., Sato, M., Sato, M., Ishii, T., and Hara, H. Internalization and degradation of hepatocyte growth factor in hepatocytes with down-regulation of the receptor/c-Met. FEBS Lett 329, 147, 1993.
    • (1993) FEBS Lett , vol.329 , pp. 147
    • Naka, D.1    Shimomura, T.2    Yoshiyama, Y.3    Sato, M.4    Sato, M.5    Ishii, T.6    Hara, H.7
  • 41
    • 0030831145 scopus 로고    scopus 로고
    • Long-term cytokine production from engineered primary human stromal cells influences human hematopoiesis in an in vivo xenograft model
    • Dao, M.A., Pepper, K.A., and Nolta, J.A. Long-term cytokine production from engineered primary human stromal cells influences human hematopoiesis in an in vivo xenograft model. Stem Cells 15, 443, 1997.
    • (1997) Stem Cells , vol.15 , pp. 443
    • Dao, M.A.1    Pepper, K.A.2    Nolta, J.A.3
  • 42
    • 0028325345 scopus 로고
    • Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3: Analysis of gene transduction of long-lived progenitors
    • Nolta, J.A., Hanley, M.B., and Kohn, D.B. Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3: analysis of gene transduction of long-lived progenitors. Blood 83, 3041, 1994.
    • (1994) Blood , vol.83 , pp. 3041
    • Nolta, J.A.1    Hanley, M.B.2    Kohn, D.B.3
  • 44
    • 33947262698 scopus 로고    scopus 로고
    • Cytokine and integrin stimulation synergize to promote higher levels of GATA-2, c-myb, and CD34 protein in primary human hematopoietic progenitors from bone marrow
    • Dao, M.A., and Nolta, J.A. Cytokine and integrin stimulation synergize to promote higher levels of GATA-2, c-myb, and CD34 protein in primary human hematopoietic progenitors from bone marrow. Blood 109, 2373, 2007.
    • (2007) Blood , vol.109 , pp. 2373
    • Dao, M.A.1    Nolta, J.A.2
  • 48
    • 0032748173 scopus 로고    scopus 로고
    • Propagation and senescence of human marrow stromal cells in culture: A simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate
    • Digirolamo, C.M., Stokes, D., Colter, D., Phinney, D.G., Class, R., and Prockop, D.J. Propagation and senescence of human marrow stromal cells in culture: a simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate. Br J Haematol 107, 275, 1999.
    • (1999) Br J Haematol , vol.107 , pp. 275
    • Digirolamo, C.M.1    Stokes, D.2    Colter, D.3    Phinney, D.G.4    Class, R.5    Prockop, D.J.6
  • 50
    • 55049084643 scopus 로고    scopus 로고
    • Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells
    • Rosova, I., Dao, M., Capoccia, B., Link, D., and Nolta, J.A. Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells. Stem Cells 8, 2173, 2008.
    • (2008) Stem Cells , vol.8 , pp. 2173
    • Rosova, I.1    Dao, M.2    Capoccia, B.3    Link, D.4    Nolta, J.A.5
  • 51
    • 0034601436 scopus 로고    scopus 로고
    • The integrin-linked kinase (ILK) suppresses anoikis
    • Attwell, S., Roskelley, C., and Dedhar, S. The integrin-linked kinase (ILK) suppresses anoikis. Oncogene 19, 3811, 2000.
    • (2000) Oncogene , vol.19 , pp. 3811
    • Attwell, S.1    Roskelley, C.2    Dedhar, S.3
  • 53
    • 84989485234 scopus 로고
    • The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells
    • Friedenstein, A.J., Chailakhjan, R.K., and Lalykina, K.S. The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells. Cell Tissue Kinet 3, 393, 1970.
    • (1970) Cell Tissue Kinet , vol.3 , pp. 393
    • Friedenstein, A.J.1    Chailakhjan, R.K.2    Lalykina, K.S.3
  • 55
  • 57
    • 47649121002 scopus 로고    scopus 로고
    • PDGF, TGF-beta, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): Transcriptional profiling can identify markers and signaling pathways important in differentiation of MSCs into adipogenic, chondrogenic, and osteogenic lineages
    • Ng, F., Boucher, S., Koh, S., Sastry, K.S., Chase, L., Laksh-mipathy, U., Choong, C., Yang, Z., Vemuri, M.C., Rao, M.S., and Tanavde, V. PDGF, TGF-beta, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in differentiation of MSCs into adipogenic, chondrogenic, and osteogenic lineages. Blood 112, 295, 2008.
    • (2008) Blood , vol.112 , pp. 295
    • Ng, F.1    Boucher, S.2    Koh, S.3    Sastry, K.S.4    Chase, L.5    Laksh-Mipathy, U.6    Choong, C.7    Yang, Z.8    Vemuri, M.C.9    Rao, M.S.10    Tanavde, V.11
  • 58
    • 0029127979 scopus 로고
    • Parathyroid hormone restores bone mass and enhances osteoblast insulin-like growth factor i gene expression in ovariectomized rats
    • Watson, P., Lazowski, D., Han, V., Fraher, L., Steer, B., and Hodsman, A. Parathyroid hormone restores bone mass and enhances osteoblast insulin-like growth factor I gene expression in ovariectomized rats. Bone 16, 357, 1995.
    • (1995) Bone , vol.16 , pp. 357
    • Watson, P.1    Lazowski, D.2    Han, V.3    Fraher, L.4    Steer, B.5    Hodsman, A.6
  • 60
    • 33747614767 scopus 로고    scopus 로고
    • Successful stem cell therapy using umbilical cord blood-derived mul-tipotent stem cells for Buerger's disease and ischemic limb disease animal model
    • Kim, S.W., Han, H., Chae, G.T., Lee, S.H., Bo, S., Yoon, J.H., Lee, Y.S., Lee, K.S., Park, H.K., and Kang, K.S. Successful stem cell therapy using umbilical cord blood-derived mul-tipotent stem cells for Buerger's disease and ischemic limb disease animal model. Stem Cells 24, 1620, 2006.
    • (2006) Stem Cells , vol.24 , pp. 1620
    • Kim, S.W.1    Han, H.2    Chae, G.T.3    Lee, S.H.4    Bo, S.5    Yoon, J.H.6    Lee, Y.S.7    Lee, K.S.8    Park, H.K.9    Kang, K.S.10


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