Analysis of receptor tyrosine kinase internalization using flow cytometry

Methods in Molecular Biology

Volumn 457, Issue , 2008, Pages 305-317

  Li, Ning ^a   Hill, Kristen S ^a   Elferink, Lisa A ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

CMet; Endocytosis; Flow cytometry; Hepatocyte growth factor; Internalin B; Receptor tyrosine kinase

Indexed keywords

EID: 84934439850     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-59745-261-8_23     Document Type: Article

References (17)

1. Booden, M. A., Eckert, L. B., Der, C. J., and Trejo, J. (2004) Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasion. Mol Cell. 24, 1990-1999.
2. Oosterhoff, J. K., Kuhne, L. C., Grootegoed, J. A., and Blok, L. J. (2005) EGF signalling in prostate cancer cell lines is inhibited by a high expression level of the endocytosis protein REPS2. Int. J. Cancer. 113, 561-567.
3. Li, L. and Cohen, S. N. (1996) Tsg101: a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells. Cell 85, 319-329.
4. Longva, K. E., Blystad, F. D., Stang, E., Larsen, A. M., Johannessen, L. E., and Madshus, I. H. (2002) Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies. J. Cell. Biol. 156, 843-854.
5. Peschard, P., Fournier, T. M., Lamorte, L., et al. (2001). Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein. Mol. Cell. 8, 995-1004.
6. Peschard, P. and Park, M. (2003) Escape from Cbl-mediated downregulation: a recurrent theme for oncogenic deregulation of receptor tyrosine kinases. Cancer Cell 3, 519-523.
7. Li, N., Xiang, G. S., Dokainish, H., Ireton, K., and Elferink, L. A. (2005) The Listeria protein internalin B mimics hepatocyte growth factor-induced receptor trafficking. Traffic 6, 459-473.
8. Shen, Y., Naujokas, M., Park, M., and Ireton, K. (2000) InIB-dependent inter-nalization of Listeria is mediated by the Met receptor tyrosine kinase. Cell 1032, 501-510.
9. Veiga, E., and Cossart, P. (2005) Listeria hijacks the clathrin-dependent endocytic machinery to invade mammalian cells. Nature Cell Biol. 7, 894-900.
10. Ireton, K., Payrastre, B., and Cossart, P. (1999) The Listeria monocytogenes protein InlB is an agonist of mammalian phosphoinositide 3-kinase. J. Biol. Chem. 274, 17025-17032.
11. Birchmeier, C., Birchmeier, W., Gherardi, E., and Vande Woude, G. F. (2003) Met, metastasis, motility and more. Nature Rev. Mol. Cell Biol. 4, 915-925.
12. Gao, C. F., and Vande Woude, G. F. (2005) HGF/SF-Met signaling in tumor progression. Cell Res. 15, 49-51.
13. Abella, J. V., Peschard, P., Naujokas, M. A., et al. (2005) Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation. Mol. Cell Biol. 25, 9632-9645.
14. Schmidt, M. H., Furnari, F. B., Cavenee, W. K., and Bogler, O. (2003) Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization. Proc. Natl. Acad. Sci. USA. 100, 6505-6510.
15. Fischer, O. M., Giordano, S., Commoglio, P. M., and Ulrich, A. (2004) Reactive oxygen species mediate Met receptor transactivation by G protein-coupled receptors and the epidermal growth factor receptor in human carcinoma cells. J. Biol. Chem. 279, 28970-28978.
16. Klausner R. D., Ashwell G., van Renswoude J., Harford J. B., Bridges K. R. (1983) Binding of apotransferrin to K562 cells: explanation of the transferrin cycle. Proc Natl Acad Sci USA. 80, 2263-6.
17. Heuser, J E., and Anderson, R. G. W. (1989) Hypertonic Media Inhibit Receptor-mediated Endocytosis by Blocking Clathrin-coated Pit Formation. J.Cell Biol. 108, 389-400