A cell profiling framework for modeling drug responses from HCS imaging

Journal of Biomolecular Screening

Volumn 15, Issue 7, 2010, Pages 858-868

  Ng, Alvin Y J ^a   Rajapakse, Jagath C ^a   Welsch, Roy E ^a,b   Matsudaira, Paul T ^a,c   Horodincu, Victor ^c   Evans, James G ^d  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d Anon Consulting   (United States)

Author keywords

cell morphology; clustering; drug profiling; high content screening (HCS)

Indexed keywords

ACTIN;

ARTICLE; CELL CULTURE; CELL PH; CELL STRUCTURE; CYTOLOGY; DRUG EFFECT; DRUG RESPONSE; HIGH CONTENT SCREENING; MACROPHAGE; MICROTUBULE; PHENOTYPE; PRIORITY JOURNAL; SCREENING; STATISTICS;

CHI-SQUARE DISTRIBUTION; CLUSTER ANALYSIS; HIGH-THROUGHPUT SCREENING ASSAYS; IMAGING, THREE-DIMENSIONAL; MACROPHAGES; MODELS, BIOLOGICAL; REPRODUCIBILITY OF RESULTS;

EID: 77956028042     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057110372256     Document Type: Article

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