Hepatocyte growth factor incorporated chitosan nanoparticles differentiate murine bone marrow mesenchymal stem cell into hepatocytes in vitro

IET Nanobiotechnology

Volumn 4, Issue 3, 2010, Pages 51-60

  Pulavendran, S ^a   Rajam, M ^a   Rose, C ^a   Mandal, A B ^a  

^a CENTRAL LEATHER RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ADVERSE EFFECT; AVERAGE SIZE; BONE MARROW MESENCHYMAL STEM CELLS; CHITOSAN NANOPARTICLES; CULTURE MEDIUM; CYTOKINES; GROWTH FACTOR; HEPATIC DIFFERENTIATION; HEPATOCYTE GROWTH FACTOR; HEPATOCYTES; IN-VITRO; NANO-DEVICES; NOVEL TECHNIQUES; REGENERATIVE MEDICINE; STEM CELL DIFFERENTIATION; THERAPEUTIC PROTEIN; TISSUE REGENERATION;

BIODEGRADABLE POLYMERS; BONE; CELL CULTURE; CHITIN; CHITOSAN; COAGULATION; FUNCTIONAL POLYMERS; GELATION; IMPLANTS (SURGICAL); NANOPARTICLES; PEPTIDES;

STEM CELLS;

CHITOSAN; DRUG CARRIER; NANOPARTICLE; SCATTER FACTOR;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CHEMISTRY; CYTOLOGY; DRUG EFFECT; LIVER CELL; MATERIALS TESTING; MESENCHYMAL STEM CELL; METHODOLOGY; MOUSE; PHYSIOLOGY; TISSUE ENGINEERING; ULTRASTRUCTURE;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CHITOSAN; DRUG CARRIERS; HEPATOCYTE GROWTH FACTOR; HEPATOCYTES; MATERIALS TESTING; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED BALB C; NANOPARTICLES; TISSUE ENGINEERING;

EID: 77956018366     PISSN: 17518741     EISSN: None     Source Type: Journal    
DOI: 10.1049/iet-nbt.2009.0014     Document Type: Article

References (33)

1. Colvin, V.L.: ' The potential environmental impact of engineered nanomaterials ', Nat. Biotechnol., 2003, 21, (10), p. 1166-1170
2. Lynch, I., Dawson, K.A., and Linse, S.: ' Detecting cryptic epitopes created by nanoparticles ', Science, 2006, (327), p. 14-19 0036-8075
3. Lagasse, E., Connors, H., and Al-Thalamy, M.: et al. ' Purified hematopoietic stem cells differentiate into hepatocytes in vivo ', Nat. Med., 2000, 6, (11), p. 1229-1234
4. Petersen, B.E., Bowen, W.C., and Patrene, K.D.: et al. ' Bone marrow as a potential source of hepatic ovel cells ', Science, 1990, 284, (5417), p. 1168-1170 0036-8075
5. Theise, N.D., Badve, S., and Saxena, R.: et al. ' Derivitation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation ', Hepatology, 2003, 31, (1), p. 235-240
6. Yamamoto, H., Quinn, G., and Asari, A.: et al. ' Differentiation of embryonic stem cells into hepatocytes: biological functions and therapeutic application ', Hepatology, 2003, 37, (5), p. 983-993
7. Schwartz, R.E., Reyes, M., Koodie, L., Jiang, Y., Blackstad, M., and Lund, T.: ' Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells ', J. Clin. Invest., 2002, 109, (10), p. 1291-1302
8. Reyes, M., and Verfaillie, C.M.: ' Characterization of multipotent adult progenitor cells, a subpopulation of mesenchymal stem cells ', Ann. NY. Acad. Sci., 2001, 938, p. 231-233
9. Taub, R.: ' Liver regeneration: from myth to mechanism ', Nat. Rev. Mol. Cell. Biol., 2004, 5, (10), p. 836-847
10. Baldini, M., Prat, M., and Gnocchi, P.: et al. ' Hepatocyte growth factor effects on mesenchymal stem cells: proliferation, migration, and differentiation ', Stem cells, 2006, 24, (1), p. 23-33
11. Higashiyama, R., Inagaki, Y., and Hong, Y.Y.: et al. ' Bone marrow-derived cells express matrix metalloproteinases and contribute to regression of liver fibrosis in mice ', Hepatology, 2007, 45, (1), p. 213-222
12. Kaido, T., Yamaoka, S., and Seto, S.: et al. ' Continuous hepatocyte growth factor supply prevents lipopolysaccharide-induced liver injury in rats ', FEBS. Lett., 1997, 411, (2-3), p. 378-382
13. Xue, F., Takahara, T., and Yata, Y.: et al. ' Hepatocyte growth factor gene therapy accelerates regeneration in cirrhotic mouse livers after hepatectomy ', Gut, 2003, 52, (5), p. 694-700
14. Wang, X., Ge, S., McNamara, G., Hao, Q.L., Crooks, G.M., and Nolta, J.A.: ' Albumin-expressing hepatocyte-like cells develop in the livers of immune-deficient mice transplanted with highly purified human stem cells ', Blood, 2003, 101, (10), p. 4201-4208
15. Neuss, S., Becher, F., Wöltje, M., Tietze, L., and Jahnen-Dechent, W.: ' Functional expression of HGF and HGF receptor/c-met in adult human mesenchymal stem cells suggests a role in cell mobilization, tissue repair, and wound healing ', Stem Cells, 2004, 22, (3), p. 405-414
16. Shi, C., Zhu, Y., Ran, X., Wang, M., Su, Y., and Cheng, T.: ' Therapeutic potential of chitosan and its derivatives in regenerative medicine ', J. Surg. Res., 2006, 133, (2), p. 185-192
17. Madihally, S.V., and Matthew, H.W.T.: ' Porous chitosan scaffolds for tissue engineering ', Biomaterials, 1999, 20, (12), p. 1133-1142 0142-9612
18. Mitra, S., Gaur, U., Ghosh, P.C., and Maitra, A.N.: ' Tumor targeted delivery of encapsulated dextran-doxorubicin conjugate using chitosan nanoparticles as carrier ', J. Control. Rel., 2001, 74, (1), p. 317-323
19. Pan, Y., Li, Y., and Zheng, J.: et al. ' Bioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo ', Int. J. Pharm., 2002, 249, (1-2), p. 139-147
20. Cetin, M., Aktas, Y., Vural, I., and Capan, Y.: ' Preparation and in vitro evaluation of bFGF-loaded chitosan nanoparticles ', Drug Deliv., 2007, 14, (8), p. 525-529
21. Calo, P., Remunan-Lopez, C., Vila-Jato, J.L., and Alonso, M.J.: ' Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers ', J. Appl. Polym. Sci., 1997, 63, (1), p. 125-132 0021-8995
22. Knaul, J.Z., Hudson, S.M., and Creber, K.A.M.: ' Crosslinking of chitosan fibers with dialdehydes: proposal of a new reaction mechanism ', J. Poly. Sci. B: Poly. Phys., 1999, 37, (11), p. 1079-1094
23. Gan, Q., and Wang, T.: ' Chitosan nanoparticle as protein delivery carrier - systematic examination of fabrication conditions for efficient loading and release ', Coll. Surf. B: Bioint., 2007, 59, (1), p. 24-34
24. McNeil, S.E.: ' Nanotechnology for the biologist ', J. Leuk. Biol., 2005, 78, (3), p. 1-10
25. Jong, W.H., Hagens, W.I., Krystek, P., Burger, M.C., Sips, A., and Geertsma, R.E.: ' Particle size-dependent organ distribution of gold nanoparticles after intravenous administration ', Biomaterials, 2008, 29, (12), p. 1912-1919 0142-9612
26. Labhasetwar, V., Song, C., and Levy, R.J.: ' Nanoparticle drug delivery system for restenosis ', Adv. Drug. Deliv. Rev., 1997, 24, (1), p. 63-85
27. De Campos, A.M., Diehold, Y., Carvalho, E.L.S., Sanchez, A., and Alonso, M.J.: ' Chitosan nanoparticles as new ocular drug delivery systems; in vitro stability, in vivo fate, and cellular toxicity ', Pharm. Res., 2004, 21, (5), p. 803-810
28. Diebold, Y., Jarrin, M., and Saez, V.: et al. ' Ocular drug delivery by liposome-chitosan nanoparticles complexes (LCS-NP) ', Biomaterials, 2007, 28, (8), p. 1553-1564 0142-9612
29. Howling, G.I., Dettmar, P.W., Goddard, P.A., Hampson, F.C., Dornish, M., and Wood, E.J.: ' The effect of chitin and chitosan on the proliferation of human skin fibroblasts and keratinocytesin vitro ', Biomaterials, 2001, 22, (22), p. 2959-2966 0142-9612
30. Tanaka, Y., Tanioka, S.I., and Tanaka, M.: et al. ' Effects of chitin and chitosan particles on BALB/c mice by oral and parenteral administration ', Biomaterials, 1997, 18, (8), p. 591-595 0142-9612
31. Kopen, G.C., Prockop, D.J., and Phinney, D.G.: ' Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains ', Proc. Natl. Acad. Sci. USA, 1999, p. 10711-10716, 96, (19)
32. Geo, J., Dennis, J.E., Muzic, R.F., Lundberg, M., and Caplan, A.I.: ' The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion ', Cells, Tissues Organs, 2001, 169, (1), p. 12-20
33. Lee, K., Kwang-Chun Kuo, T., and Whang-Peng, J.: et al. ' In vitro hepatic differentiation of human mesenchymal stem cells ', Hepatology, 2006, 40, (6), p. 1275-1284