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Volumn 67, Issue 8, 2009, Pages 439-450

Mendelian randomization in nutritional epidemiology

Author keywords

Mendelian randomization; Nutritional epidemiology; Review

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ALDEHYDE DEHYDROGENASE ISOENZYME 2; C REACTIVE PROTEIN; FIBRINOGEN; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1; HEMOGLOBIN A1C; HOMOCYSTEINE; INTERLEUKIN 18; INTERLEUKIN 6; LACTASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR;

EID: 77956018249     PISSN: 00296643     EISSN: 17534887     Source Type: Journal    
DOI: 10.1111/j.1753-4887.2009.00218.x     Document Type: Review
Times cited : (46)

References (65)
  • 1
    • 84921763923 scopus 로고    scopus 로고
    • New York Oxford: Oxford University Press
    • Willett W. Nutritional Epidemiology. New York Oxford: Oxford University Press; 1998.
    • (1998) Nutritional Epidemiology
    • Willett, W.1
  • 2
    • 0027406769 scopus 로고
    • Intake of trans fatty acids and risk of coronary heart disease among women
    • Willett WC, Stampfer MJ,Manson JE, et al. Intake of trans fatty acids and risk of coronary heart disease among women. Lancet. 1993;341:581-585.
    • (1993) Lancet , vol.341 , pp. 581-585
    • Willett, W.C.1    Stampfer, M.J.2    Manson, J.E.3
  • 3
    • 43849111166 scopus 로고    scopus 로고
    • The long-term effect of lifestyle interventions to prevent diabetes in the China da Qing Diabetes Prevention Study: A 20-year follow-up study
    • Li G, Zhang P, Wang J, et al. The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study. Lancet. 2008;371:1783-1789.
    • (2008) Lancet , vol.371 , pp. 1783-1789
    • Li, G.1    Zhang, P.2    Wang, J.3
  • 5
    • 38049023073 scopus 로고    scopus 로고
    • Clustered environments and randomized genes: A fundamental distinction between conventional and genetic epidemiology
    • Smith GD, Lawlor DA, Harbord R, Timpson N, Day I, Ebrahim S. Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology. PLoS Med. 2007;4:e352.
    • (2007) PLoS Med , vol.4
    • Smith, G.D.1    Lawlor, D.A.2    Harbord, R.3    Timpson, N.4    Day, I.5    Ebrahim, S.6
  • 6
    • 0037320413 scopus 로고    scopus 로고
    • Commentary: Balancing quantity and quality when designing epidemiological studies
    • Phillips A. Commentary: balancing quantity and quality when designing epidemiological studies. Int J Epidemiol. 2003;32:58-59.
    • (2003) Int J Epidemiol , vol.32 , pp. 58-59
    • Phillips, A.1
  • 7
    • 18444405551 scopus 로고    scopus 로고
    • What can Mendelian randomisation tell us about modifiable behavioural and environmental exposures?
    • Davey Smith G, Ebrahim S. What can Mendelian randomisation tell us about modifiable behavioural and environmental exposures?. BMJ. 2005;330:1076-1079.
    • (2005) BMJ , vol.330 , pp. 1076-1079
    • Davey Smith, G.1    Ebrahim, S.2
  • 8
    • 34547682094 scopus 로고    scopus 로고
    • Mendelian randomization as an instrumental variable approach to causal inference
    • Didelez V, Sheehan N. Mendelian randomization as an instrumental variable approach to causal inference. Stat Methods Med Res. 2007;16:309-330.
    • (2007) Stat Methods Med Res , vol.16 , pp. 309-330
    • Didelez, V.1    Sheehan, N.2
  • 10
    • 0022656494 scopus 로고
    • Apolipoprotein e isoforms, serum cholesterol, and cancer
    • Katan MB. Apolipoprotein E isoforms, serum cholesterol, and cancer. Lancet. 1986;1:507-508.
    • (1986) Lancet , vol.1 , pp. 507-508
    • Katan, M.B.1
  • 11
    • 0024299370 scopus 로고
    • Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
    • Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science. 1988;240:622-630.
    • (1988) Science , vol.240 , pp. 622-630
    • Mahley, R.W.1
  • 12
    • 1942436221 scopus 로고    scopus 로고
    • Mendelian randomization: Prospects, potentials, and limitations
    • Smith GD, Ebrahim S. Mendelian randomization: prospects, potentials, and limitations. Int J Epidemiol. 2004;33:30-42.
    • (2004) Int J Epidemiol , vol.33 , pp. 30-42
    • Smith, G.D.1    Ebrahim, S.2
  • 13
    • 33645084282 scopus 로고    scopus 로고
    • Limits to causal inference based on Mendelian randomization: A comparison with randomized controlled trials
    • Nitsch D, Molokhia M, Smeeth L, DeStavola BL, Whittaker JC, Leon DA. Limits to causal inference based on Mendelian randomization: a comparison with randomized controlled trials. Am J Epidemiol. 2006;163:397-403.
    • (2006) Am J Epidemiol , vol.163 , pp. 397-403
    • Nitsch, D.1    Molokhia, M.2    Smeeth, L.3    Destavola, B.L.4    Whittaker, J.C.5    Leon, D.A.6
  • 14
    • 40849083720 scopus 로고    scopus 로고
    • Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
    • Lawlor DA, Harbord RM, Sterne JA, Timpson N, Davey Smith G. Mendelian randomization: using genes as instruments for making causal inferences in epidemiology. Stat Med. 2008;27:1133-1163.
    • (2008) Stat Med , vol.27 , pp. 1133-1163
    • Lawlor, D.A.1    Harbord, R.M.2    Sterne, J.A.3    Timpson, N.4    Davey Smith, G.5
  • 15
    • 28244481060 scopus 로고    scopus 로고
    • C-reactive protein and its role in metabolic syndrome: Mendelian randomisation study
    • Timpson NJ, Lawlor DA, Harbord RM, et al. C-reactive protein and its role in metabolic syndrome: Mendelian randomisation study. Lancet. 2005;366:1954-1959.
    • (2005) Lancet , vol.366 , pp. 1954-1959
    • Timpson, N.J.1    Lawlor, D.A.2    Harbord, R.M.3
  • 16
    • 34247273705 scopus 로고    scopus 로고
    • Mendelian randomization suggests no causal association between C-reactive protein and carotid intima-media thickness in the young Finns study
    • KivimakiM, Lawlor DA, Eklund C, et al.Mendelian randomization suggests no causal association between C-reactive protein and carotid intima-media thickness in the young Finns study. Arterioscler Thromb Vasc Biol. 2007;27:978-979.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 978-979
    • Kivimaki, M.1    Lawlor, D.A.2    Eklund, C.3
  • 17
    • 54149096173 scopus 로고    scopus 로고
    • Lifetime body mass index and later atherosclerosis risk in young adults: Examining causal links using Mendelian randomization in the Cardiovascular Risk in Young Finns study
    • Kivimaki M, Davey Smith G, Timpson NJ, et al. Lifetime body mass index and later atherosclerosis risk in young adults: examining causal links using Mendelian randomization in the Cardiovascular Risk in Young Finns study. Eur Heart J. 2008;25:2552-2560.
    • (2008) Eur Heart J , vol.25 , pp. 2552-2560
    • Kivimaki, M.1    Davey Smith, G.2    Timpson, N.J.3
  • 18
    • 4444364446 scopus 로고    scopus 로고
    • An integrated approach to the meta-analysis of genetic association studies using Mendelian randomization
    • Minelli C, Thompson JR, Tobin MD, Abrams KR. An integrated approach to the meta-analysis of genetic association studies using Mendelian randomization. Am J Epidemiol. 2004; 160:445-452.
    • (2004) Am J Epidemiol , vol.160 , pp. 445-452
    • Minelli, C.1    Thompson, J.R.2    Tobin, M.D.3    Abrams, K.R.4
  • 19
    • 41549104622 scopus 로고    scopus 로고
    • Alcohol intake and blood pressure: A systematic review implementing a Mendelian randomization approach
    • Chen L, Davey Smith G, Harbord RM, Lewis SJ. Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach. PLoS Med. 2008;5:e52.
    • (2008) PLoS Med , vol.5
    • Chen, L.1    Davey Smith, G.2    Harbord, R.M.3    Lewis, S.J.4
  • 20
    • 0034529563 scopus 로고    scopus 로고
    • An introduction to instrumental variables for epidemiologists
    • Greenland S. An introduction to instrumental variables for epidemiologists. Int J Epidemiol. 2000;29:1102.
    • (2000) Int J Epidemiol , vol.29 , pp. 1102
    • Greenland, S.1
  • 21
    • 0346307687 scopus 로고    scopus 로고
    • Instrumental variables with weak instruments
    • Staiger D, Stock JH. Instrumental variables with weak instruments. Econometrica. 1997;65:557-586.
    • (1997) Econometrica , vol.65 , pp. 557-586
    • Staiger, D.1    Stock, J.H.2
  • 22
    • 52349083201 scopus 로고    scopus 로고
    • Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease - A Mendelian randomisation study
    • Linsel-Nitschke P, Gotz A, Erdmann J, et al. Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease - a Mendelian randomisation study. PLoS ONE. 2008;3:e2986.
    • (2008) PLoS ONE , vol.3
    • Linsel-Nitschke, P.1    Gotz, A.2    Erdmann, J.3
  • 23
    • 0036166191 scopus 로고    scopus 로고
    • Risk factors for esophageal cancer and the multiple occurrence of carcinoma in the upper aerodigestive tract
    • Morita M, Saeki H, Mori M, Kuwano H, Sugimachi K. Risk factors for esophageal cancer and the multiple occurrence of carcinoma in the upper aerodigestive tract. Surgery. 2002;131 (Suppl):S1-S6.
    • (2002) Surgery , vol.131 , Issue.SUPPL.
    • Morita, M.1    Saeki, H.2    Mori, M.3    Kuwano, H.4    Sugimachi, K.5
  • 24
    • 0026540609 scopus 로고
    • Alcohol and cancer
    • Blot WJ. Alcohol and cancer. Cancer Res. 1992; 52(Suppl):S2119-S2123.
    • (1992) Cancer Res , vol.52 , Issue.SUPPL.
    • Blot, W.J.1
  • 25
    • 23844550544 scopus 로고    scopus 로고
    • Alcohol ALDH2 and esophageal cancer: A meta-analysis which illustrates the potentials and limitations of a Mendelian randomization approach
    • Lewis SJ, Smith GD. Alcohol, ALDH2, and esophageal cancer: a meta-analysis which illustrates the potentials and limitations of a Mendelian randomization approach. Cancer Epidemiol Biomarkers Prev. 2005;14:1967-1971.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 1967-1971
    • Lewis, S.J.1    Smith, G.D.2
  • 26
    • 0026034835 scopus 로고
    • Acetaldehyde metabolism in different aldehyde dehydrogenase-2 genotypes
    • Enomoto N, Takase S, Yasuhara M, Takada A. Acetaldehyde metabolism in different aldehyde dehydrogenase-2 genotypes. Alcohol Clin Exp Res. 1991;15:141-144.
    • (1991) Alcohol Clin Exp Res , vol.15 , pp. 141-144
    • Enomoto, N.1    Takase, S.2    Yasuhara, M.3    Takada, A.4
  • 27
    • 0034891326 scopus 로고    scopus 로고
    • Relation between average alcohol consumption and disease: An overview
    • Gutjahr E, Gmel G, Rehm J. Relation between average alcohol consumption and disease: an overview. Eur Addict Res. 2001;7:117-127.
    • (2001) Eur Addict Res , vol.7 , pp. 117-127
    • Gutjahr, E.1    Gmel, G.2    Rehm, J.3
  • 28
    • 0036848436 scopus 로고    scopus 로고
    • Genetic polymorphisms of alcohol and aldehyde dehydrogenases and glutathione S-transferase M1 and drinking, smoking, and diet in Japanese men with esophageal squamous cell carcinoma
    • Yokoyama A, Kato H, Yokoyama T, et al. Genetic polymorphisms of alcohol and aldehyde dehydrogenases and glutathione S-transferase M1 and drinking, smoking, and diet in Japanese men with esophageal squamous cell carcinoma. Carcinogenesis. 2002;23:1851-1859.
    • (2002) Carcinogenesis , vol.23 , pp. 1851-1859
    • Yokoyama, A.1    Kato, H.2    Yokoyama, T.3
  • 29
    • 34548019243 scopus 로고    scopus 로고
    • Lactase persistence and bitter taste response: Instrumental variables and Mendelian randomization in epidemiologic studies of dietary factors and cancer risk
    • Sacerdote C, Guarrera S, Smith GD, et al. Lactase persistence and bitter taste response: instrumental variables and Mendelian randomization in epidemiologic studies of dietary factors and cancer risk. Am J Epidemiol. 2007;166:576-581.
    • (2007) Am J Epidemiol , vol.166 , pp. 576-581
    • Sacerdote, C.1    Guarrera, S.2    Smith, G.D.3
  • 32
    • 0037458815 scopus 로고    scopus 로고
    • Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide
    • Kim UK, Jorgenson E, Coon H, Leppert M, Risch N, Drayna D. Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide. Science. 2003;299:1221-1225.
    • (2003) Science , vol.299 , pp. 1221-1225
    • Kim, U.K.1    Jorgenson, E.2    Coon, H.3    Leppert, M.4    Risch, N.5    Drayna, D.6
  • 33
    • 2342594532 scopus 로고    scopus 로고
    • The unkindest cup
    • Weiss KM. The unkindest cup. Lancet. 2004;363:1489-1490.
    • (2004) Lancet , vol.363 , pp. 1489-1490
    • Weiss, K.M.1
  • 34
    • 34248594090 scopus 로고    scopus 로고
    • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
    • Frayling TM, Timpson NJ, Weedon MN, et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science. 2007;316:889-894.
    • (2007) Science , vol.316 , pp. 889-894
    • Frayling, T.M.1    Timpson, N.J.2    Weedon, M.N.3
  • 35
    • 43549117072 scopus 로고    scopus 로고
    • Use of multiple biomarkers to improve the prediction of death from cardiovascular causes
    • Zethelius B, Berglund L, Sundstrom J, et al. Use of multiple biomarkers to improve the prediction of death from cardiovascular causes. N Engl J Med. 2008;358:2107-2116.
    • (2008) N Engl J Med , vol.358 , pp. 2107-2116
    • Zethelius, B.1    Berglund, L.2    Sundstrom, J.3
  • 36
    • 33745312587 scopus 로고    scopus 로고
    • Adiponectin genetic variability, plasma adiponectin, and cardiovascular risk in patients with type 2 diabetes
    • Qi L, Doria A, Manson JE, et al. Adiponectin genetic variability, plasma adiponectin, and cardiovascular risk in patients with type 2 diabetes. Diabetes. 2006;55:1512-1516.
    • (2006) Diabetes , vol.55 , pp. 1512-1516
    • Qi, L.1    Doria, A.2    Manson, J.E.3
  • 37
    • 0034704893 scopus 로고    scopus 로고
    • C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
    • DOI 10.1056/NEJM200003233421202
    • Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med. 2000;342:836-843. (Pubitemid 30165206)
    • (2000) New England Journal of Medicine , vol.342 , Issue.12 , pp. 836-843
    • Ridker, P.M.1    Hennekens, C.H.2    Buring, J.E.3    Rifai, N.4
  • 38
    • 33746427608 scopus 로고    scopus 로고
    • Dietary fibers and glycemic load, obesity, and plasma adiponectin levels in women with type 2 diabetes
    • Qi L, Meigs JB, Liu S, Manson JE, Mantzoros C, Hu FB. Dietary fibers and glycemic load, obesity, and plasma adiponectin levels in women with type 2 diabetes. Diabetes Care. 2006;29:1501-1505.
    • (2006) Diabetes Care , vol.29 , pp. 1501-1505
    • Qi, L.1    Meigs, J.B.2    Liu, S.3    Manson, J.E.4    Mantzoros, C.5    Hu, F.B.6
  • 39
    • 1542390804 scopus 로고    scopus 로고
    • Leisure-time physical activity and reduced plasma levels of obesity-related inflammatory markers
    • Pischon T, Hankinson SE, Hotamisligil GS, Rifai N, Rimm EB. Leisure-time physical activity and reduced plasma levels of obesity-related inflammatory markers. Obes Res. 2003; 11:1055-1064.
    • (2003) Obes Res , vol.11 , pp. 1055-1064
    • Pischon, T.1    Hankinson, S.E.2    Hotamisligil, G.S.3    Rifai, N.4    Rimm, E.B.5
  • 40
    • 34047135047 scopus 로고    scopus 로고
    • An interleukin-18 polymorphism is associated with reduced serum concentrations and better physical functioning in older people
    • Frayling TM, Rafiq S, Murray A, et al. An interleukin-18 polymorphism is associated with reduced serum concentrations and better physical functioning in older people. J Gerontol A Biol Sci Med Sci. 2007;62:73-78.
    • (2007) J Gerontol A Biol Sci Med Sci , vol.62 , pp. 73-78
    • Frayling, T.M.1    Rafiq, S.2    Murray, A.3
  • 41
    • 36849038962 scopus 로고    scopus 로고
    • Interleukin-6 receptor gene variations, plasma interleukin-6 levels, and type 2 diabetes in U.S. women
    • Qi L, Rifai N, Hu FB. Interleukin-6 receptor gene variations, plasma interleukin-6 levels, and type 2 diabetes in U.S. women. Diabetes. 2007;56:3075-3081.
    • (2007) Diabetes , vol.56 , pp. 3075-3081
    • Qi, L.1    Rifai, N.2    Hu, F.B.3
  • 42
    • 33748438338 scopus 로고    scopus 로고
    • Fibrinogen and coronary heart disease: Test of causality by"Mendelian randomization."
    • Keavney B, Danesh J, Parish S, et al. Fibrinogen and coronary heart disease: test of causality by"Mendelian randomization." Int J Epidemiol. 2006;35:935-943.
    • (2006) Int J Epidemiol , vol.35 , pp. 935-943
    • Keavney, B.1    Danesh, J.2    Parish, S.3
  • 43
    • 12344309062 scopus 로고    scopus 로고
    • Homocysteine and stroke: Evidence on a causal link from Mendelian randomisation
    • Casas JP, Bautista LE, Smeeth L, Sharma P, Hingorani AD. Homocysteine and stroke: evidence on a causal link from Mendelian randomisation. Lancet. 2005;365:224-232.
    • (2005) Lancet , vol.365 , pp. 224-232
    • Casas, J.P.1    Bautista, L.E.2    Smeeth, L.3    Sharma, P.4    Hingorani, A.D.5
  • 45
    • 0037469255 scopus 로고    scopus 로고
    • C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: An 8-year follow-up of 14,719 initially healthy American women
    • Ridker PM, Buring JE, Cook NR, Rifai N. C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14,719 initially healthy American women. Circulation. 2003;107:391-397.
    • (2003) Circulation , vol.107 , pp. 391-397
    • Ridker, P.M.1    Buring, J.E.2    Cook, N.R.3    Rifai, N.4
  • 46
    • 0036157628 scopus 로고    scopus 로고
    • C-reactive protein and cardiovascular disease: A review of risk prediction and interventions
    • de Ferranti S, Rifai N. C-reactive protein and cardiovascular disease: a review of risk prediction and interventions. Clin Chim Acta. 2002;317:1-15.
    • (2002) Clin Chim Acta , vol.317 , pp. 1-15
    • De Ferranti, S.1    Rifai, N.2
  • 47
    • 18244407548 scopus 로고    scopus 로고
    • Association of C-reactive protein with blood pressure and hypertension: Life course confounding and Mendelian randomization tests of causality
    • Davey Smith G, Lawlor DA, Harbord R, et al. Association of C-reactive protein with blood pressure and hypertension: life course confounding and Mendelian randomization tests of causality. Arterioscler Thromb Vasc Biol. 2005;25:1051-1056.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1051-1056
    • Davey Smith, G.1    Lawlor, D.A.2    Harbord, R.3
  • 48
    • 0036226512 scopus 로고    scopus 로고
    • Polymorphism in the human C-reactive protein (CRP) gene, plasma concentrations of CRP, and the risk of future arterial thrombosis
    • Zee RY, Ridker PM. Polymorphism in the human C-reactive protein (CRP) gene, plasma concentrations of CRP, and the risk of future arterial thrombosis. Atherosclerosis. 2002;162:217-219.
    • (2002) Atherosclerosis , vol.162 , pp. 217-219
    • Zee, R.Y.1    Ridker, P.M.2
  • 49
    • 33748425073 scopus 로고    scopus 로고
    • Insight into the nature of the CRP-coronary event association using Mendelian randomization
    • Casas JP, Shah T, Cooper J, et al. Insight into the nature of the CRP-coronary event association using Mendelian randomization. Int J Epidemiol. 2006;35:922-931.
    • (2006) Int J Epidemiol , vol.35 , pp. 922-931
    • Casas, J.P.1    Shah, T.2    Cooper, J.3
  • 50
    • 1842587885 scopus 로고    scopus 로고
    • C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease
    • Danesh J, Wheeler JG, Hirschfield GM, et al. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med. 2004;350:1387-1397.
    • (2004) N Engl J Med , vol.350 , pp. 1387-1397
    • Danesh, J.1    Wheeler, J.G.2    Hirschfield, G.M.3
  • 51
    • 51549111362 scopus 로고    scopus 로고
    • Does high C-reactive protein concentration increase atherosclerosis? the Whitehall II Study
    • Kivimaki M, Lawlor DA, Smith GD, et al. Does high C-reactive protein concentration increase atherosclerosis? TheWhitehall II Study. PLoS ONE. 2008;3:e3013.
    • (2008) PLoS ONE , vol.3
    • Kivimaki, M.1    Lawlor, D.A.2    Smith, G.D.3
  • 52
    • 50949134384 scopus 로고    scopus 로고
    • Inflammation, insulin resistance, and diabetes - Mendelian randomization using CRP haplotypes points upstream
    • Brunner EJ, Kivimaki M, Witte DR, et al. Inflammation, insulin resistance, and diabetes - Mendelian randomization using CRP haplotypes points upstream. PLoS Med. 2008; 5:e155.
    • (2008) PLoS Med , vol.5
    • Brunner, E.J.1    Kivimaki, M.2    Witte, D.R.3
  • 53
    • 84926426742 scopus 로고    scopus 로고
    • Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: An individual participant metaanalysis
    • Danesh J, Lewington S, Thompson SG, et al. Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant metaanalysis. JAMA. 2005;294:1799-1809.
    • (2005) JAMA , vol.294 , pp. 1799-1809
    • Danesh, J.1    Lewington, S.2    Thompson, S.G.3
  • 54
    • 0032906750 scopus 로고    scopus 로고
    • Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: Metabolic significance, risks and impact on folate requirement
    • Bailey LB, Gregory JF, 3rd. Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement. J Nutr. 1999;129:919-922.
    • (1999) J Nutr , vol.129 , pp. 919-922
    • Bailey, L.B.1    Gregory Iii, J.F.2
  • 55
    • 34147171031 scopus 로고    scopus 로고
    • Admixture mapping of an allele affecting interleukin 6 soluble receptor and interleukin 6 levels
    • Reich D, Patterson N, Ramesh V, et al. Admixture mapping of an allele affecting interleukin 6 soluble receptor and interleukin 6 levels. Am J Hum Genet. 2007;80:716-726.
    • (2007) Am J Hum Genet , vol.80 , pp. 716-726
    • Reich, D.1    Patterson, N.2    Ramesh, V.3
  • 56
    • 38449100724 scopus 로고    scopus 로고
    • Assessing intrauterine influences on offspring health outcomes: Can epidemiological studies yield robust findings?
    • Smith GD. Assessing intrauterine influences on offspring health outcomes: can epidemiological studies yield robust findings?. Basic Clin Pharmacol Toxicol. 2008;102:245-256.
    • (2008) Basic Clin Pharmacol Toxicol , vol.102 , pp. 245-256
    • Smith, G.D.1
  • 57
    • 33748259233 scopus 로고    scopus 로고
    • Adult consequences of fetal growth restriction
    • Barker DJ. Adult consequences of fetal growth restriction. Clin Obstet Gynecol. 2006;49:270-283.
    • (2006) Clin Obstet Gynecol , vol.49 , pp. 270-283
    • Barker, D.J.1
  • 58
    • 33845613507 scopus 로고    scopus 로고
    • Birth weight, stress, and the metabolic syndrome in adult life
    • Phillips DI, Jones A, Goulden PA. Birth weight, stress, and the metabolic syndrome in adult life. Ann N Y Acad Sci. 2006;1083:28-36.
    • (2006) Ann N y Acad Sci , vol.1083 , pp. 28-36
    • Phillips, D.I.1    Jones, A.2    Goulden, P.A.3
  • 59
    • 33746565284 scopus 로고    scopus 로고
    • Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease
    • Martins IJ, Hone E, Foster JK, et al. Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease. Mol Psychiatry. 2006;11:721-736.
    • (2006) Mol Psychiatry , vol.11 , pp. 721-736
    • Martins, I.J.1    Hone, E.2    Foster, J.K.3
  • 61
    • 0037442092 scopus 로고    scopus 로고
    • Population stratification and spurious allelic association
    • Cardon LR, Palmer LJ. Population stratification and spurious allelic association. Lancet. 2003;361:598-604.
    • (2003) Lancet , vol.361 , pp. 598-604
    • Cardon, L.R.1    Palmer, L.J.2
  • 62
    • 41849122765 scopus 로고    scopus 로고
    • A cautionary note on the use of Mendelian randomization to infer causation in observational epidemiology
    • author reply 416-417
    • Bochud M, Chiolero A, Elston RC, Paccaud F. A cautionary note on the use of Mendelian randomization to infer causation in observational epidemiology. Int J Epidemiol. 2008;37:414-416; author reply 416-417.
    • (2008) Int J Epidemiol , vol.37 , pp. 414-416
    • Bochud, M.1    Chiolero, A.2    Elston, R.C.3    Paccaud, F.4
  • 63
    • 38449101833 scopus 로고    scopus 로고
    • Imprinting in human disease with special reference to transient neonatal diabetes and Beckwith- Wiedemann syndrome
    • Temple IK. Imprinting in human disease with special reference to transient neonatal diabetes and Beckwith- Wiedemann syndrome. Endocr Dev. 2007;12:113-123.
    • (2007) Endocr Dev , vol.12 , pp. 113-123
    • Temple, I.K.1
  • 64
    • 44349142294 scopus 로고    scopus 로고
    • Common variants near MC4R are associated with fat mass, weight and risk of obesity
    • Loos RJ, Lindgren CM, Li S, et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet. 2008;40:768-775.
    • (2008) Nat Genet , vol.40 , pp. 768-775
    • Loos, R.J.1    Lindgren, C.M.2    Li, S.3
  • 65
    • 41649103682 scopus 로고    scopus 로고
    • A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
    • Hung RJ, McKay JD, Gaborieau V, et al. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature. 2008;452:633-637.
    • (2008) Nature , vol.452 , pp. 633-637
    • Hung, R.J.1    McKay, J.D.2    Gaborieau, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.