Procalcitonin is useful in identifying bacteraemia among children with pneumonia

Scandinavian Journal of Infectious Diseases

Volumn 42, Issue 9, 2010, Pages 644-649

  Nascimento Carvalho, Cristiana M ^a   Cardoso, Maria Regina A ^b   Barral, Aldina ^a   Araújo Neto, César A ^a   Guerin, Sylvie ^c   Saukkoriipi, Annika ^d   Paldanius, Mika ^d   Vainionpää, Raija ^e   Lebon, Pierre ^c   Leinonen, Maija ^d   Ruuskanen, Olli ^e   Gendrel, Dominique ^c  

^a FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^e UNIVERSITY OF TURKU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; PROCALCITONIN;

ARTICLE; BACTEREMIA; BACTERIAL INFECTION; BACTERIUM DETECTION; BLOOD CULTURE; CHILD; FEMALE; HUMAN; LUNG INFILTRATE; MAJOR CLINICAL STUDY; MALE; PNEUMONIA; VIRUS DETECTION;

BACTEREMIA; CALCITONIN; CHILD, PRESCHOOL; COMMUNITY-ACQUIRED INFECTIONS; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; INTERFERON-ALPHA; MALE; PNEUMONIA, BACTERIAL; PNEUMONIA, VIRAL; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; PROTEIN PRECURSORS; REPRODUCIBILITY OF RESULTS; ROC CURVE; STATISTICS, NONPARAMETRIC;

EID: 77956014968     PISSN: 00365548     EISSN: 16511980     Source Type: Journal    
DOI: 10.3109/00365541003796775     Document Type: Article

References (25)

1. Rudan I, Boschi-Pinto C, Biloglav Z, Mulholland K, Campbell H. Epidemiology and etiology of childhood pneumonia. Bull World Health Organ 2008;86:408-416
2. Nascimento-Carvalho CM. Etiology of childhood community acquired pneumonia and its implications for vaccination. Braz J Infect Dis 2001;5:87-97.
3. World Health Organization. Integrated management of childhood illness. Chart booklet WC 503.2. Geneva: WHO; 2008. Available at: http://whqlibdoc.who. int/publications/2008/9789241597289-eng.pdf (accessed January 15, 2009).
4. Shann F. Etiology of severe pneumonia in children in developing countries. Pediatr Infect Dis J 1986;5:247-252
5. Hale KA, Isaacs D. Antibiotics in childhood pneumonia. Pediatr Resp Rev 2006;7:45-51.
6. Peltola V, Ruuskanen O. Respiratory viral infections in developing countries: common, severe, and unrecognized. Clin Infect Dis 2008;46:58-60.
7. Cilla G, Onate E, Perez-Yarza EG, Montes M, Vicente D, Perez-Trallero E. Viruses in community-acquired pneumonia in children aged less than 3 years old: high rate of viral coinfection. J Med Virol 2008;80:1843-1849
8. Korppi M, Don M, Valent F, Canciani M. The value of clinical features in differentiating between viral, pneumococcal and atypical bacterial pneumonia in children. Acta Paediatr 2008;97:943-947
9. Mäkelä MJ, Puhakka T, Ruuskanen O, Leinonen M, Saikku P, Kimpimäki M, et al. Viruses and bacteria in the etiology of the common cold. J Clin Microbiol 1998;36:539-542
10. Hyypiä T, Puhakka T, Ruuskanen O, Mäkelä M, Arola A, Arstila P. Molecular diagnosis of human rhinovirus infection: comparison with virus isolation. J Clin Microbiol 1998;36: 2081-2083
11. Juvén T, Mertsola J, Waris M, Leinonen M, Meurman O, Roivainen M, et al. Etiology of community-acquired pneumonia in 254 hospitalized children. Pediatr Infect Dis J 2000;19:293-298
12. Saukkoriipi A, Palmu A, Kilpi T, Leinonen M. Real-time quantitative PCR for the detection of Streptococcus pneumoniae in the middle ear fluid of children with acute otitis media. Mol Cell Probes 2002;16:385-390
13. Korppi M, Paldanius M, Hyvarinen A, Nevalainen A. Simkania negevensis and newly diagnosed asthma: a case-control study in 1-to 6-year-old children. Respirology 2006; 11:80-83
14. Nascimento-Carvalho CM, Ribeiro CT, Cardoso MR, Barral A, Araújo-Neto CA, Oliveira JR, et al. The role of respiratory viral infections among children hospitalized for community-acquired pneumonia in a developing country. Pediatr Infect Dis J 2008;27:939-941
15. Assicot M, Gendrel D, Carsin H, Raymond J, Guilbaud J, Bohuon C. High serum procalcitonin concentrations in patients with sepsis and infection. Lancet 1993;341:515-518
16. Gendrel D, Raymond J, Coste J, Moulin F, Lorrot M, Guérin S, et al. Comparison of procalcitonin with C-reactive protein, interleukin 6 and interferon-alpha for differentiation of bacterial vs. viral infections. Pediatr Infect Dis J 1999; 18:875-881
17. Moulin F, Raymond J, Lorrot M, Marc E, Coste J, Iniguez JL, et al. Procalcitonin in children admitted to hospital with community acquired pneumonia. Arch Dis Child 2001;84: 332-336
18. Prat C, Domínguez J, Rodrigo C, Giménez M, Azuara M, Jiménez O, et al. Procalcitonin, C-reactive protein and leukocyte count in children with lower respiratory tract infection. Pediatr Infect Dis J 2003;22:963-968
19. Müller B, Harbarth S, Stolz D, Bingisser R, Mueller C, Leuppi J, et al. Diagnostic and prognostic accuracy of clinical and laboratory parameters in community-acquired pneumonia. BMC Infect Dis 2007;7:10.
20. Toikka P, Irjala K, Juvén T, Virkki R, Mertsola J, Leinonen M, et al. Serum procalcitonin, C-reactive protein and interleukin-6 for distinguishing bacterial and viral pneumonia in children. Pediatr Infect Dis J 2000;19: 598-602.
21. Christ-Crain M, Stolz D, Bingisser R, Müller C, Miedinger D, Huber PR, et al. Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial. Am J Respir Crit Care Med 2006;174:84-93.
22. Niederman MS. Biological markers to determine eligibility in trials for community-acquired pneumonia: a focus on procalcitonin. Clin Infect Dis 2008;47(Suppl 3):S127-32.
23. Maniaci V, Dauber A, Weiss S, Nylen E, Becker KL, Bachur R. Procalcitonin in young febrile infants for the detection of serious bacterial infections. Pediatrics 2008;122:701-710
24. Korppi M, Leinonen M, Ruuskanen O. Pneumococcal serology in children's respiratory infections. Eur J Clin Microbiol Infect Dis 2008;27:167-175
25. Price GE, Gaszewsk-Mastarlarz A, Moskophidis D. The role of alpha/beta and gamma interferons in development of immunity to influenza A virus in mice. J Virol 2000;74: 3996-4003.