Anti-angiogenic activity of heparin-like polysulfonated polymeric drugs in 3D human cell culture

Biomaterials

Volumn 31, Issue 31, 2010, Pages 7863-7872

  García Fernández, Luis ^a,b   Halstenberg, Sven ^c   Unger, Ronald E ^c   Aguilar, María R ^a,b   Kirkpatrick, C James ^c   San Román, Julio ^a,b  

^a INSTITUTO DE CIENCIA Y TECNOLOGÍA DE POLÍMEROS   (Spain)

^b BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^c UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Angiogenesis; Confocal microscopy; ECM (extracellular matrix); Endothelial cell; Fibrinogen; Fibroblast growth factor

Indexed keywords

ACTIVE POLYMERS; ANGIOGENESIS; ANGIOGENIC GROWTH FACTORS; ANIMAL EXPERIMENTS; ANTI-ANGIOGENIC ACTIVITY; ANTI-PROLIFERATIVE; BLOOD VESSEL-LIKE STRUCTURES; BUTYL ACRYLATES; CELL MODEL; ECM (EXTRACELLULAR MATRIX); FIBRIN MATRIX; FIBRINOGEN; FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; HYDROPHILIC MONOMERS; HYDROPHOBIC MONOMERS; IMMUNOSTAINING PROTOCOL; IN-VITRO; IN-VIVO EXPERIMENTS; LASER SCANNING; MITOGENIC EFFECTS; SEMI-QUANTITATIVE; SULFONIC ACID; VINYL PYRROLIDONE;

ACIDS; ANIMAL CELL CULTURE; BLOOD VESSELS; BUTANE; CONFOCAL MICROSCOPY; ENDOTHELIAL CELLS; ENZYME INHIBITION; EXPERIMENTS; FIBROBLASTS; HYDROPHILICITY; MONOMERS; PEPTIDES; POLYMERS; POLYSACCHARIDES; SELF ASSEMBLY; THREE DIMENSIONAL; TISSUE; TISSUE CULTURE;

CELL CULTURE;

2 ACRYLAMIDO 2 METHYLPROPANE SULFONIC ACID; 5 AMINO 2 NAPHTHALENESULFONIC ACID; ACRYLIC ACID BUTYL ESTER; AMINO ACID; ANGIOGENIC FACTOR; FIBRIN; GROWTH FACTOR; HEPARIN; MONOMER; POVIDONE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ARTICLE; BAGG ALBINO MOUSE; CELL ADHESION; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN 3T3; CONFOCAL LASER MICROSCOPY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HUMAN; HUMAN CELL CULTURE; HYDROPHOBICITY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MACROMOLECULE; NONHUMAN; PRIORITY JOURNAL; THREE DIMENSIONAL IMAGING; TISSUE CULTURE;

ACTINS; ANGIOGENESIS INHIBITORS; BIOLOGICAL ASSAY; CAPILLARIES; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELLS, CULTURED; CYTOSKELETON; ENDOTHELIAL CELLS; FIBRIN; FIBROBLAST GROWTH FACTOR 2; HEPARIN; HUMANS; MICROSCOPY, CONFOCAL; NEOVASCULARIZATION, PHYSIOLOGIC; POLYMERS; SULFONIC ACIDS; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

ANIMALIA;

EID: 77956010702     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.07.022     Document Type: Article

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