Leads for development of new naphthalenesulfonate derivatives with enhanced antiangiogenic activity. Crystal structure of acidic fibroblast growth factor in complex with 5-amino-2-naphthalenesulfonate

Journal of Biological Chemistry

Volumn 278, Issue 24, 2003, Pages 21774-21781

  Fernández Tornero, Carlos ^a   Lozano, Rosa M ^a   Redondo Horcajo, Mariano ^a   Gómez, Ana M ^b   López, José C ^b   Quesada, Ernesto ^b   Uriel, Clara ^b   Valverdell, Serafín ^b   Cuevas, Pedro ^c   Romero, Antonio ^a   Giménez Gallego, Guillermo ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b INSTITUTO DE QUÍMICA ORGÁNICA GENERAL   (Spain)

^c HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL MEMBRANES; CRYSTAL STRUCTURE; NITROGEN COMPOUNDS; STEREOCHEMISTRY; TUMORS;

FIBROBLASTS;

ESTERS;

5 AMINO 2 NAPHTHALENESULFONATE DERIVATIVE; FIBROBLAST GROWTH FACTOR; NAPHTHALENESULFONIC ACID DERIVATIVE; SURAMIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; CANCER INHIBITION; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; MITOGENESIS; MOLECULAR INTERACTION; MOLECULAR SIZE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

ANGIOGENESIS INHIBITORS; ANIMALS; CELL DIVISION; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLAST GROWTH FACTOR 1; HEPARIN; MICE; MICE, INBRED C57BL; MODELS, MOLECULAR; NAPHTHALENESULFONATES; PROTEIN BINDING; SODIUM;

ANIMALIA;

EID: 0037484261     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212833200     Document Type: Article

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