-
1
-
-
33750349255
-
Critical appraisal of brain pathology staging related to presymptomatic and symptomatic cases of sporadic Parkinson's disease
-
Halliday GM, Del Tredici K, Braak H. Critical appraisal of brain pathology staging related to presymptomatic and symptomatic cases of sporadic Parkinson's disease. J Neural Transm Suppl 2006, 70: 99-103.
-
(2006)
J Neural Transm Suppl
, vol.70
, pp. 99-103
-
-
Halliday, G.M.1
Del Tredici, K.2
Braak, H.3
-
3
-
-
0030882856
-
α-Synuclein in Lewy bodies
-
Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M. α-Synuclein in Lewy bodies. Nature 1997, 388: 839-840.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
4
-
-
0028985267
-
The precursor protein of non-Aβ component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system
-
Iwai A, Masliah E, Yoshimoto M, Ge N, Flanagan L, de Silva HA, et al. The precursor protein of non-Aβ component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system. Neuron 1995, 14: 467-475.
-
(1995)
Neuron
, vol.14
, pp. 467-475
-
-
Iwai, A.1
Masliah, E.2
Yoshimoto, M.3
Ge, N.4
Flanagan, L.5
De Silva, H.A.6
-
5
-
-
33845952600
-
Cytosolic proteins regulate α-synuclein dissociation from presynaptic membranes
-
Wislet-Gendebien S, D'Souza C, Kawarai T, St George-Hyslop P, Westaway D, Fraser P, et al. Cytosolic proteins regulate α-synuclein dissociation from presynaptic membranes. J Biol Chem 2006, 281: 32148-32155.
-
(2006)
J Biol Chem
, vol.281
, pp. 32148-32155
-
-
Wislet-Gendebien, S.1
D'souza, C.2
Kawarai, T.3
St George-Hyslop, P.4
Westaway, D.5
Fraser, P.6
-
6
-
-
33847320669
-
The 5'-untranslated region of Parkinson's disease α-synuclein messengerRNA contains a predicted iron responsive element
-
Friedlich AL, Tanzi RE, Rogers JT. The 5'-untranslated region of Parkinson's disease α-synuclein messengerRNA contains a predicted iron responsive element. Mol Psychiatry 2007, 12: 222-223.
-
(2007)
Mol Psychiatry
, vol.12
, pp. 222-223
-
-
Friedlich, A.L.1
Tanzi, R.E.2
Rogers, J.T.3
-
7
-
-
0031990490
-
Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease
-
Kruger R, Kuhn W, Muller T, Woitalla D, Graeber M, Kosel S, etal. Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease. Nat Genet 1998, 18: 106-108.
-
(1998)
Nat Genet
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
-
8
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, et al. Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science 1997, 276: 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
-
9
-
-
10744230149
-
The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia
-
Zarranz JJ, Alegre J, Gomez-Esteban JC, Lezcano E, Ros R, Ampuero I, et al. The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia. Ann Neurol 2004, 55: 164-173.
-
(2004)
Ann Neurol
, vol.55
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gomez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
Ampuero, I.6
-
10
-
-
0242300619
-
α-Synuclein locus triplication causes Parkinson's disease
-
Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, Kachergus J, et al. α-Synuclein locus triplication causes Parkinson's disease. Science 2003, 302: 841.
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
-
11
-
-
0024356620
-
Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease
-
Dexter DT, Wells FR, Lees AJ, Agid F, Agid Y, Jenner P, et al. Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease. J Neurochem 1989, 52: 1830-1836.
-
(1989)
J Neurochem
, vol.52
, pp. 1830-1836
-
-
Dexter, D.T.1
Wells, F.R.2
Lees, A.J.3
Agid, F.4
Agid, Y.5
Jenner, P.6
-
12
-
-
0026746512
-
Neuromelanin-containing neurons of the substantia nigra accumulate iron and aluminum in Parkinson's disease: A LAMMA study
-
Good PF, Olanow CW, Perl DP. Neuromelanin-containing neurons of the substantia nigra accumulate iron and aluminum in Parkinson's disease: a LAMMA study. Brain Res 1992, 593: 343-346.
-
(1992)
Brain Res
, vol.593
, pp. 343-346
-
-
Good, P.F.1
Olanow, C.W.2
Perl, D.P.3
-
13
-
-
42049123661
-
Midbrain iron content in early Parkinson disease: A potential biomarker of disease status
-
Martin WR, Wieler M, Gee M. Midbrain iron content in early Parkinson disease: a potential biomarker of disease status. Neurology 2008, 70: 1411-1417.
-
(2008)
Neurology
, vol.70
, pp. 1411-1417
-
-
Martin, W.R.1
Wieler, M.2
Gee, M.3
-
14
-
-
34249034604
-
Individual dopaminergic neurons show raised iron levels in Parkinson disease
-
Oakley AE, Collingwood JF, Dobson J, Love G, Perrott HR, Edwardson JA, et al. Individual dopaminergic neurons show raised iron levels in Parkinson disease. Neurology 2007, 68: 1820-1825.
-
(2007)
Neurology
, vol.68
, pp. 1820-1825
-
-
Oakley, A.E.1
Collingwood, J.F.2
Dobson, J.3
Love, G.4
Perrott, H.R.5
Edwardson, J.A.6
-
15
-
-
0024557734
-
Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains
-
Riederer P, Sofic E, Rausch WD, Schmidt B, Reynolds GP, Jellinger K, et al. Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains. J Neurochem 1989, 52: 515-520.
-
(1989)
J Neurochem
, vol.52
, pp. 515-520
-
-
Riederer, P.1
Sofic, E.2
Rausch, W.D.3
Schmidt, B.4
Reynolds, G.P.5
Jellinger, K.6
-
16
-
-
27844547163
-
In vivo detection of iron and neuromelanin by transcranial sonography: A new approach for early detection of substantia nigra damage
-
Zecca L, Berg D, Arzberger T, Ruprecht P, Rausch WD, Musicco M, et al. In vivo detection of iron and neuromelanin by transcranial sonography: a new approach for early detection of substantia nigra damage. Mov Disord 2005, 20: 1278-1285.
-
(2005)
Mov Disord
, vol.20
, pp. 1278-1285
-
-
Zecca, L.1
Berg, D.2
Arzberger, T.3
Ruprecht, P.4
Rausch, W.D.5
Musicco, M.6
-
17
-
-
11144304136
-
Time dependent effects of 6-OHDA lesions on iron level and neuronal loss in rat nigrostriatal system
-
Wang J, Jiang H, Xie JX. Time dependent effects of 6-OHDA lesions on iron level and neuronal loss in rat nigrostriatal system. Neurochem Res 2004, 29: 2239-2243.
-
(2004)
Neurochem Res
, vol.29
, pp. 2239-2243
-
-
Wang, J.1
Jiang, H.2
Xie, J.X.3
-
18
-
-
33749506725
-
Neuroprotective effects of iron chelator Desferal on dopaminergic neurons in the substantia nigra of rats with iron-overload
-
Jiang H, Luan Z, Wang J, Xie J. Neuroprotective effects of iron chelator Desferal on dopaminergic neurons in the substantia nigra of rats with iron-overload. Neurochem Int 2006, 49: 605-609.
-
(2006)
Neurochem Int
, vol.49
, pp. 605-609
-
-
Jiang, H.1
Luan, Z.2
Wang, J.3
Xie, J.4
-
19
-
-
34250014148
-
Ferroportin1 and hephaestin are involved in the nigral iron accumulation of 6-OHDA-lesioned rats
-
Wang J, Jiang H, Xie JX. Ferroportin1 and hephaestin are involved in the nigral iron accumulation of 6-OHDA-lesioned rats. Eur J Neurosci 2007, 25: 2766-2772.
-
(2007)
Eur J Neurosci
, vol.25
, pp. 2766-2772
-
-
Wang, J.1
Jiang, H.2
Xie, J.X.3
-
20
-
-
0034663039
-
The A53T α-synuclein mutation increases irondependent aggregation and toxicity
-
Ostrerova-Golts N, Petrucelli L, Hardy J, Lee JM, Farer M, Wolozin B. The A53T α-synuclein mutation increases irondependent aggregation and toxicity. J Neurosci 2000, 20: 6048-6054.
-
(2000)
J Neurosci
, vol.20
, pp. 6048-6054
-
-
Ostrerova-Golts, N.1
Petrucelli, L.2
Hardy, J.3
Lee, J.M.4
Farer, M.5
Wolozin, B.6
-
21
-
-
0037013194
-
Magnesium inhibits spontaneous and iron-induced aggregation of α-synuclein
-
Golts N, Snyder H, Frasier M, Theisler C, Choi P, Wolozin B. Magnesium inhibits spontaneous and iron-induced aggregation of α-synuclein. J Biol Chem 2002, 277: 16116-16123.
-
(2002)
J Biol Chem
, vol.277
, pp. 16116-16123
-
-
Golts, N.1
Snyder, H.2
Frasier, M.3
Theisler, C.4
Choi, P.5
Wolozin, B.6
-
22
-
-
34548021006
-
Copper- and iron-induced differential fibril formation in α-synuclein: TEM study
-
Bharathi, Indi SS, Rao KS. Copper- and iron-induced differential fibril formation in α-synuclein: TEM study. Neurosci Lett 2007, 424: 78-82.
-
(2007)
Neurosci Lett
, vol.424
, pp. 78-82
-
-
Bharathi Indi, S.S.1
Rao, K.S.2
-
23
-
-
0037085288
-
Formation and removal of α-synuclein aggregates in cells exposed to mitochondrial inhibitors
-
Lee HJ, Shin SY, Choi C, Lee YH, Lee SJ. Formation and removal of α-synuclein aggregates in cells exposed to mitochondrial inhibitors. J Biol Chem 2002, 277: 5411-5417.
-
(2002)
J Biol Chem
, vol.277
, pp. 5411-5417
-
-
Lee, H.J.1
Shin, S.Y.2
Choi, C.3
Lee, Y.H.4
Lee, S.J.5
-
24
-
-
0042164632
-
Dopamine release rather than content in the caudate putamen is associated with behavioral changes in the iron rat model of Parkinson's disease
-
Junxia X, Hong J, Wenfang C, Ming Q. Dopamine release rather than content in the caudate putamen is associated with behavioral changes in the iron rat model of Parkinson's disease. Exp Neurol 2003, 182: 483-489.
-
(2003)
Exp Neurol
, vol.182
, pp. 483-489
-
-
Junxia, X.1
Hong, J.2
Wenfang, C.3
Ming, Q.4
-
25
-
-
33744977254
-
The pathogenesis of cell death in Parkinson's disease
-
Jenner P, Olanow CW. The pathogenesis of cell death in Parkinson's disease. Neurology 2006, 66: S24-36.
-
(2006)
Neurology
, vol.66
-
-
Jenner, P.1
Olanow, C.W.2
-
27
-
-
34249085348
-
Pathogenesis of Parkinson's disease: Oxidative stress, environmental impact factors and inflammatory processes
-
Yuan H, Zheng JC, Liu P, Zhang SF, Xu JY, Bai LM. Pathogenesis of Parkinson's disease: oxidative stress, environmental impact factors and inflammatory processes. Neurosci Bull 2007, 2: 125-130.
-
(2007)
Neurosci Bull
, vol.2
, pp. 125-130
-
-
Yuan, H.1
Zheng, J.C.2
Liu, P.3
Zhang, S.F.4
Xu, J.Y.5
Bai, L.M.6
-
28
-
-
0026034279
-
Iron and aluminum increase in the substantia nigra of patients with Parkinson's disease: An X-ray microanalysis
-
Hirsch EC, Brandel JP, Galle P, Javoy-Agid F, Agid Y. Iron and aluminum increase in the substantia nigra of patients with Parkinson's disease: an X-ray microanalysis. J Neurochem 1991, 56: 446-451.
-
(1991)
J Neurochem
, vol.56
, pp. 446-451
-
-
Hirsch, E.C.1
Brandel, J.P.2
Galle, P.3
Javoy-Agid, F.4
Agid, Y.5
-
29
-
-
0032870588
-
Time course of dopaminergic cell death and changes in iron, ferritin and transferrin levels in the rat substantia nigra after 6-hydroxydopamine (6-OHDA) lesioning
-
He Y, Lee T, Leong SK. Time course of dopaminergic cell death and changes in iron, ferritin and transferrin levels in the rat substantia nigra after 6-hydroxydopamine (6-OHDA) lesioning. Free Radic Res 1999, 31: 103-112.
-
(1999)
Free Radic Res
, vol.31
, pp. 103-112
-
-
He, Y.1
Lee, T.2
Leong, S.K.3
-
30
-
-
0030607202
-
Increased iron in the substantia nigra of 6-OHDA induced parkinsonian rats: A nuclear microscopy study
-
He Y, Thong PS, Lee T, Leong SK, Shi CY, Wong PT, et al. Increased iron in the substantia nigra of 6-OHDA induced parkinsonian rats: a nuclear microscopy study. Brain Res 1996, 735: 149-153.
-
(1996)
Brain Res
, vol.735
, pp. 149-153
-
-
He, Y.1
Thong, P.S.2
Lee, T.3
Leong, S.K.4
Shi, C.Y.5
Wong, P.T.6
-
31
-
-
34250888826
-
Myricetin reduces 6-hydroxydopamine-induced dopamine neuron degeneration in rats
-
Ma ZG, Wang J, Jiang H, Liu TW, Xie JX. Myricetin reduces 6-hydroxydopamine-induced dopamine neuron degeneration in rats. Neuroreport 2007, 18: 1181-1185.
-
(2007)
Neuroreport
, vol.18
, pp. 1181-1185
-
-
Ma, Z.G.1
Wang, J.2
Jiang, H.3
Liu, T.W.4
Xie, J.X.5
-
32
-
-
0028266425
-
Iron accumulation in the substantia nigra of 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced hemiparkinsonian monkeys
-
Mochizuki H, Imai H, Endo K, Yokomizo K, Murata Y, Hattori N, et al. Iron accumulation in the substantia nigra of 1-methyl- 4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced hemiparkinsonian monkeys. Neurosci Lett 1994, 168: 251-253.
-
(1994)
Neurosci Lett
, vol.168
, pp. 251-253
-
-
Mochizuki, H.1
Imai, H.2
Endo, K.3
Yokomizo, K.4
Murata, Y.5
Hattori, N.6
-
33
-
-
0028045734
-
Increased iron in the substantia nigra compacta of the MPTP-lesioned hemiparkinsonian African green monkey: Evidence from proton microprobe elemental microanalysis
-
Temlett JA, Landsberg JP, Watt F, Grime GW. Increased iron in the substantia nigra compacta of the MPTP-lesioned hemiparkinsonian African green monkey: evidence from proton microprobe elemental microanalysis. J Neurochem 1994, 62: 134-146.
-
(1994)
J Neurochem
, vol.62
, pp. 134-146
-
-
Temlett, J.A.1
Landsberg, J.P.2
Watt, F.3
Grime, G.W.4
-
34
-
-
59049094805
-
Rg1 reduces nigral iron levels of MPTP-treated C57BL6 mice by regulating certain iron transport proteins
-
Wang J, Xu HM, Yang HD, Du XX, Jiang H, Xie JX. Rg1 reduces nigral iron levels of MPTP-treated C57BL6 mice by regulating certain iron transport proteins. Neurochem Int 2009, 54: 43-48.
-
(2009)
Neurochem Int
, vol.54
, pp. 43-48
-
-
Wang, J.1
Xu, H.M.2
Yang, H.D.3
Du, X.X.4
Jiang, H.5
Xie, J.X.6
-
35
-
-
0242712032
-
Increased DMT1 expression and iron content in MPTP-treated C57BL/6 mice
-
Jiang H, Qian ZM, Xie JX. Increased DMT1 expression and iron content in MPTP-treated C57BL/6 mice. Acta Physiol Sin 2003, 55: 571-576.
-
(2003)
Acta Physiol Sin
, vol.55
, pp. 571-576
-
-
Jiang, H.1
Qian, Z.M.2
Xie, J.X.3
-
37
-
-
44849084558
-
Single particle characterization of iron-induced pore-forming α-synuclein oligomers
-
Kostka M, Hogen T, Danzer KM, Levin J, Habeck M, Wirth A, et al. Single particle characterization of iron-induced pore-forming α-synuclein oligomers. J Biol Chem 2008, 283: 10992-11003.
-
(2008)
J Biol Chem
, vol.283
, pp. 10992-11003
-
-
Kostka, M.1
Hogen, T.2
Danzer, K.M.3
Levin, J.4
Habeck, M.5
Wirth, A.6
-
38
-
-
0034648298
-
The Haber-Weiss reaction and mechanisms of toxicity
-
Kehrer JP. The Haber-Weiss reaction and mechanisms of toxicity. Toxicology 2000, 149: 43-50.
-
(2000)
Toxicology
, vol.149
, pp. 43-50
-
-
Kehrer, J.P.1
-
39
-
-
0034674652
-
Dityrosine cross-linking promotes formation of stable α-synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies
-
Souza JM, Giasson BI, Chen Q, Lee VM, Ischiropoulos H. Dityrosine cross-linking promotes formation of stable α-synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies. J Biol Chem 2000, 275: 18344-18349.
-
(2000)
J Biol Chem
, vol.275
, pp. 18344-18349
-
-
Souza, J.M.1
Giasson, B.I.2
Chen, Q.3
Lee, V.M.4
Ischiropoulos, H.5
|