메뉴 건너뛰기




Volumn , Issue , 2010, Pages

Down's syndrome with alzheimer's disease-like pathology: What can it teach us about the amyloid cascade hypothesis?

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E;

EID: 77955963776     PISSN: None     EISSN: 20900252     Source Type: Journal    
DOI: 10.4061/2010/175818     Document Type: Article
Times cited : (7)

References (32)
  • 1
    • 18044364799 scopus 로고    scopus 로고
    • Down syndrome, Alzheimer's disease and seizures
    • Menendez M., Down syndrome, Alzheimer's disease and seizures Brain Development 2005 27 4 246 252
    • (2005) Brain Development , vol.27 , Issue.4 , pp. 246-252
    • Menendez, M.1
  • 4
    • 0029618430 scopus 로고
    • The amyloid peptide and its precursor in Alzheimer's disease
    • Octave J.-N., The amyloid peptide and its precursor in Alzheimer's disease Reviews in the Neurosciences 1995 6 4 287 316
    • (1995) Reviews in the Neurosciences , vol.6 , Issue.4 , pp. 287-316
    • Octave, J.-N.1
  • 5
    • 0035997231 scopus 로고    scopus 로고
    • Biogenesis and metabolism of Alzheimer's disease A amyloid peptides
    • Evin G., Weidemann A., Biogenesis and metabolism of Alzheimer's disease A amyloid peptides Peptides 2002 23 7 1285 1297
    • (2002) Peptides , vol.23 , Issue.7 , pp. 1285-1297
    • Evin, G.1    Weidemann, A.2
  • 6
    • 26244462301 scopus 로고    scopus 로고
    • Proteolytic mechanisms in amyloid- metabolismml: Therapeutic implications for Alzheimer's disease
    • Vardy E. R., Catto A. J., Hooper N. M., Proteolytic mechanisms in amyloid- metabolismml: therapeutic implications for Alzheimer's disease Trends in Molecular Medicine 2005 11 10 464 472
    • (2005) Trends in Molecular Medicine , vol.11 , Issue.10 , pp. 464-472
    • Vardy, E.R.1    Catto, A.J.2    Hooper, N.M.3
  • 8
    • 49749099317 scopus 로고    scopus 로고
    • Protein expression of BACE1, BACE2 and APP in Down syndrome brains
    • Cheon M. S., Dierssen M., Kim S. H., Lubec G., Protein expression of BACE1, BACE2 and APP in Down syndrome brains Amino Acids 2008 35 2 339 343
    • (2008) Amino Acids , vol.35 , Issue.2 , pp. 339-343
    • Cheon, M.S.1    Dierssen, M.2    Kim, S.H.3    Lubec, G.4
  • 10
    • 0026597063 scopus 로고
    • Alzheimer's disease: The amyloid cascade hypothesis
    • Hardy J. A., Higgins G. A., Alzheimer's disease: the amyloid cascade hypothesis Science 1992 256 5054 184 185
    • (1992) Science , vol.256 , Issue.5054 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 11
    • 23844553466 scopus 로고    scopus 로고
    • Neuropsychological function in nondemented carriers of presenilin-1 mutations
    • Ringman J. M., Diaz-Olavarrieta C., Rodriguez Y., Neuropsychological function in nondemented carriers of presenilin-1 mutations Neurology 2005 65 4 552 558
    • (2005) Neurology , vol.65 , Issue.4 , pp. 552-558
    • Ringman, J.M.1    Diaz-Olavarrieta, C.2    Rodriguez, Y.3
  • 12
    • 0023038114 scopus 로고
    • Cerebral amyloid angiopathy in Down's syndrome
    • Belza M. G., Urich H., Cerebral amyloid angiopathy in Down's syndrome Clinical Neuropathology 1986 5 6 257 260
    • (1986) Clinical Neuropathology , vol.5 , Issue.6 , pp. 257-260
    • Belza, M.G.1    Urich, H.2
  • 13
    • 0025908356 scopus 로고
    • The consortium to establish a registry for Alzheimer's disease (CERAD) part II: Standardization of the neuropathologic assessment of Alzheimer's disease
    • Mirra S. S., Heyman A., McKeel D., The consortium to establish a registry for Alzheimer's disease (CERAD) part II: standardization of the neuropathologic assessment of Alzheimer's disease Neurology 1991 41 4 479 486
    • (1991) Neurology , vol.41 , Issue.4 , pp. 479-486
    • Mirra, S.S.1    Heyman, A.2    McKeel, D.3
  • 14
    • 33749150163 scopus 로고    scopus 로고
    • Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
    • Braak H., Alafuzoff I., Arzberger T., Kretzschmar H., Tredici K., Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry Acta Neuropathologica 2006 112 4 389 404
    • (2006) Acta Neuropathologica , vol.112 , Issue.4 , pp. 389-404
    • Braak, H.1    Alafuzoff, I.2    Arzberger, T.3    Kretzschmar, H.4    Tredici, K.5
  • 15
    • 17644426053 scopus 로고    scopus 로고
    • Cognitive status correlates with neuropathologic stage in Parkinson disease
    • Braak H., Rb U., Jansen Steur E. N. H., Del Tredici K., de Vos R. A. I., Cognitive status correlates with neuropathologic stage in Parkinson disease Neurology 2005 64 8 1404 1410
    • (2005) Neurology , vol.64 , Issue.8 , pp. 1404-1410
    • Braak, H.1    Rb, U.2    Jansen Steur, E.N.H.3    Del Tredici, K.4    De Vos, R.A.I.5
  • 16
    • 0024342769 scopus 로고
    • Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease
    • Rumble B., Retallack R., Hilbich C., Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease The New England Journal of Medicine 1989 320 22 1446 1452
    • (1989) The New England Journal of Medicine , vol.320 , Issue.22 , pp. 1446-1452
    • Rumble, B.1    Retallack, R.2    Hilbich, C.3
  • 17
    • 0030249956 scopus 로고    scopus 로고
    • Comparative investigation of neurofibrillary damage in the temporal lobe in Alzheimer's disease, Down's syndrome and dementia pugilistica
    • McKenzie J. E., Roberts G. W., Royston M. C., Comparative investigation of neurofibrillary damage in the temporal lobe in Alzheimer's disease, Down's syndrome and dementia pugilistica Neurodegeneration 1996 5 3 259 264
    • (1996) Neurodegeneration , vol.5 , Issue.3 , pp. 259-264
    • McKenzie, J.E.1    Roberts, G.W.2    Royston, M.C.3
  • 18
    • 68849122813 scopus 로고    scopus 로고
    • Anti-amyloid treatments in Alzheimer's disease
    • Sapra M., Kim K. Y., Anti-amyloid treatments in Alzheimer's disease Recent Patents on CNS Drug Discovery 2009 4 2 143 148
    • (2009) Recent Patents on CNS Drug Discovery , vol.4 , Issue.2 , pp. 143-148
    • Sapra, M.1    Kim, K.Y.2
  • 19
    • 3242737470 scopus 로고    scopus 로고
    • Challenging the amyloid cascade hypothesis: Senile plaques and amyloid- as protective adaptations to Alzheimer disease
    • Lee H. G., Casadesus G., Zhu X., Takeda A., Perry G., Smith M. A., Challenging the amyloid cascade hypothesis: senile plaques and amyloid- as protective adaptations to Alzheimer disease Annals of the New York Academy of Sciences 2004 1019 1 4
    • (2004) Annals of the New York Academy of Sciences , vol.1019 , pp. 1-4
    • Lee, H.G.1    Casadesus, G.2    Zhu, X.3    Takeda, A.4    Perry, G.5    Smith, M.A.6
  • 20
    • 58449125183 scopus 로고    scopus 로고
    • Progress in Alzheimer's disease drug discovery: An update
    • Williams M., Progress in Alzheimer's disease drug discovery: an update Current Opinion in Investigational Drugs 2009 10 1 23 34
    • (2009) Current Opinion in Investigational Drugs , vol.10 , Issue.1 , pp. 23-34
    • Williams, M.1
  • 21
    • 47149108940 scopus 로고    scopus 로고
    • Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: A randomised, double-blind, placebo-controlled study
    • Doody R. S., Gavrilova S. I., Sano M., Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study The Lancet 2008 372 9634 207 215
    • (2008) The Lancet , vol.372 , Issue.9634 , pp. 207-215
    • Doody, R.S.1    Gavrilova, S.I.2    Sano, M.3
  • 22
    • 77955969792 scopus 로고    scopus 로고
    • Dimebon's effect may challenge amyloid theory
    • Sullivan M. G., Dimebon's effect may challenge amyloid theory Clinical Neurology News 2009 5 7 11
    • (2009) Clinical Neurology News , vol.5 , Issue.7 , pp. 11
    • Sullivan, M.G.1
  • 23
    • 3142734397 scopus 로고    scopus 로고
    • Genetic basis of neurodegeneration in familial Alzheimer's disease
    • Kowalska A., Genetic basis of neurodegeneration in familial Alzheimer's disease Polish Journal of Pharmacology 2004 56 2 171 178
    • (2004) Polish Journal of Pharmacology , vol.56 , Issue.2 , pp. 171-178
    • Kowalska, A.1
  • 24
    • 0034551780 scopus 로고    scopus 로고
    • Preselinin-1 P264L knock-in mutation: Differential effects on a production, amyloid deposition, and neuronal vulnerability
    • Siman R., Reaume A. G., Savage M. J., Preselinin-1 P264L knock-in mutation: differential effects on a production, amyloid deposition, and neuronal vulnerability The Journal of Neuroscience 2000 20 23 8717 8726
    • (2000) The Journal of Neuroscience , vol.20 , Issue.23 , pp. 8717-8726
    • Siman, R.1    Reaume, A.G.2    Savage, M.J.3
  • 27
    • 26244457842 scopus 로고    scopus 로고
    • Mortality is associated with apolipoprotein e 4 in nondemented adults with Down syndrome
    • Zigman W. B., Jenkins E. C., Tycko B., Schupf N., Silverman W., Mortality is associated with apolipoprotein E 4 in nondemented adults with Down syndrome Neuroscience Letters 2005 390 2 93 97
    • (2005) Neuroscience Letters , vol.390 , Issue.2 , pp. 93-97
    • Zigman, W.B.1    Jenkins, E.C.2    Tycko, B.3    Schupf, N.4    Silverman, W.5
  • 28
    • 23644459835 scopus 로고    scopus 로고
    • Molecular mechanisms initiating amyloid -fibril formation in Alzheimer's disease
    • Kirkitadze M. D., Kowalska A., Molecular mechanisms initiating amyloid -fibril formation in Alzheimer's disease Acta Biochimica Polonica 2005 52 2 417 423
    • (2005) Acta Biochimica Polonica , vol.52 , Issue.2 , pp. 417-423
    • Kirkitadze, M.D.1    Kowalska, A.2
  • 29
    • 1842510004 scopus 로고    scopus 로고
    • Early A accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain
    • Ingelsson M., Fukumoto H., Newell K. L., Early A accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain Neurology 2004 62 6 925 931
    • (2004) Neurology , vol.62 , Issue.6 , pp. 925-931
    • Ingelsson, M.1    Fukumoto, H.2    Newell, K.L.3
  • 30
    • 33645830313 scopus 로고    scopus 로고
    • Vicious cycles within the neuropathophysiologic mechanisms of Alzheimer's disease
    • Standridge J. B., Vicious cycles within the neuropathophysiologic mechanisms of Alzheimer's disease Current Alzheimer Research 2006 3 2 95 108
    • (2006) Current Alzheimer Research , vol.3 , Issue.2 , pp. 95-108
    • Standridge, J.B.1
  • 31
    • 33748069154 scopus 로고    scopus 로고
    • Toxicity mediated by soluble oligomers of -amyloid(142) on cholinergic SN56.B5.G4 cells
    • Heinitz K., Beck M., Schliebs R., Perez-Polo J. R., Toxicity mediated by soluble oligomers of -amyloid(142) on cholinergic SN56.B5.G4 cells Neurochemistry 2006 98 6 1930 1945
    • (2006) Neurochemistry , vol.98 , Issue.6 , pp. 1930-1945
    • Heinitz, K.1    Beck, M.2    Schliebs, R.3    Perez-Polo, J.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.