BACE-2 is overexpressed in Down's syndrome

Experimental Neurology

Volumn 182, Issue 2, 2003, Pages 335-345

  Barbiero, L ^a   Benussi, L ^a   Ghidoni, R ^a   Alberici, A ^a   Russo, C ^b   Schettini, G ^b   Pagano, S F ^c   Parati, E A ^c   Mazzoli, F ^a   Nicosia, F ^a   Signorini, S ^a   Feudatari, E ^a   Binetti, G ^a  

^a IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

Alzheimer disease; Amyloid precursor protein; APP processing; BACE 2; Down's syndrome; Embryonic neural stem cells; Fetal brain; Fibroblasts; Overexpression; Secretase

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BETA SECRETASE 2; MESSENGER RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL ASSAY; CELL COMPARTMENTALIZATION; CHROMOSOME 21; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; DOWN SYNDROME; EMBRYO; ENZYME ANALYSIS; ENZYME DEGRADATION; EXTRACELLULAR SPACE; FETUS; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR WEIGHT; PLAQUE FORMING CELL; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN SECRETION; RIBONUCLEASE PROTECTION ASSAY; SEQUENCE HOMOLOGY; SKIN FIBROBLAST; STEM CELL; WESTERN BLOTTING;

EID: 0043198120     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4886(03)00049-9     Document Type: Article

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