메뉴 건너뛰기




Volumn 12, Issue 3, 2010, Pages 300-308

Interaction of oxazaphosphorines with multidrug resistance-associated protein 4 (MRP4)

Author keywords

cyclophosphamide; cytotoxicity; drug transporter; ifosfamide; multidrug resistance associated protein 4

Indexed keywords

ADEFOVIR DIPIVOXIL; BUTHIONINE SULFOXIMINE; CELECOXIB; CLOFIBRATE; CYCLOPHOSPHAMIDE; DICLOFENAC; IFOSFAMIDE; MESSENGER RNA; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 4; VERLUKAST; ABCC4 PROTEIN, HUMAN; ANTINEOPLASTIC AGENT; MULTIDRUG RESISTANCE PROTEIN; PHOSPHORUS DERIVATIVE; PRIMER DNA;

EID: 77955944179     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/s12248-010-9189-x     Document Type: Article
Times cited : (7)

References (35)
  • 1
    • 0024779132 scopus 로고
    • P-glycoprotein: Multidrug-resistance and a superfamily of membrane-associated transport proteins
    • 1:CAS:528:DyaK3cXmvFagsg%3D%3D 2574119
    • PF Juranka RL Zastawny V Ling 1989 P-glycoprotein: multidrug-resistance and a superfamily of membrane-associated transport proteins Faseb J. 3 2583 92 1:CAS:528:DyaK3cXmvFagsg%3D%3D 2574119
    • (1989) Faseb J. , vol.3 , pp. 2583-92
    • Juranka, P.F.1    Zastawny, R.L.2    Ling, V.3
  • 2
    • 0034614112 scopus 로고    scopus 로고
    • Analysis of the MRP4 drug resistance profile in transfected NIH3T3 cells
    • 10.1093/jnci/92.23.1934 1:CAS:528:DC%2BD3cXptVegsr4%3D 11106685
    • K Lee AJ Klein-Szanto GD Kruh 2000 Analysis of the MRP4 drug resistance profile in transfected NIH3T3 cells J Natl Cancer Inst. 92 1934 40 10.1093/jnci/92.23.1934 1:CAS:528:DC%2BD3cXptVegsr4%3D 11106685
    • (2000) J Natl Cancer Inst. , vol.92 , pp. 1934-40
    • Lee, K.1    Klein-Szanto, A.J.2    Kruh, G.D.3
  • 3
    • 4344632950 scopus 로고    scopus 로고
    • Mrp4 confers resistance to topotecan and protects the brain from chemotherapy
    • 10.1128/MCB.24.17.7612-7621.2004 1:CAS:528:DC%2BD2cXntVKhurs%3D 15314169
    • M Leggas M Adachi GL Scheffer D Sun P Wielinga G Du, et al. 2004 Mrp4 confers resistance to topotecan and protects the brain from chemotherapy Mol Cell Biol 24 7612 21 10.1128/MCB.24.17.7612-7621.2004 1:CAS:528: DC%2BD2cXntVKhurs%3D 15314169
    • (2004) Mol Cell Biol , vol.24 , pp. 7612-21
    • Leggas, M.1    Adachi, M.2    Scheffer, G.L.3    Sun, D.4    Wielinga, P.5    Du, G.6
  • 4
    • 18044375868 scopus 로고    scopus 로고
    • Expression of multidrug transporter MRP4/ABCC4 is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecan in vitro
    • 10.1158/1535-7163.MCT-04-0161 1:CAS:528:DC%2BD2MXjtFegs7o%3D 15827327
    • MD Norris J Smith K Tanabe P Tobin C Flemming GL Scheffer, et al. 2005 Expression of multidrug transporter MRP4/ABCC4 is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecan in vitro Mol Cancer Ther. 4 547 53 10.1158/1535-7163.MCT-04-0161 1:CAS:528:DC%2BD2MXjtFegs7o%3D 15827327
    • (2005) Mol Cancer Ther. , vol.4 , pp. 547-53
    • Norris, M.D.1    Smith, J.2    Tanabe, K.3    Tobin, P.4    Flemming, C.5    Scheffer, G.L.6
  • 5
    • 8544241727 scopus 로고    scopus 로고
    • The prognostic significance of expression of the multidrug resistance-associated protein (MRP) in primary breast cancer
    • 1:CAS:528:DyaK2sXlvV2nsLo%3D 9275026
    • K Nooter G Brutel de la Riviere MP Look KE van Wingerden SC Henzen-Logmans RJ Scheper, et al. 1997 The prognostic significance of expression of the multidrug resistance-associated protein (MRP) in primary breast cancer Br J Cancer 76 486 93 1:CAS:528:DyaK2sXlvV2nsLo%3D 9275026
    • (1997) Br J Cancer , vol.76 , pp. 486-93
    • Nooter, K.1    Brutel De La Riviere, G.2    Look, M.P.3    Van Wingerden, K.E.4    Henzen-Logmans, S.C.5    Scheper, R.J.6
  • 6
    • 20044364737 scopus 로고    scopus 로고
    • Clinical role of multidrug resistance protein 1 expression in chemotherapy resistance in early-stage breast cancer: The Austrian Breast and Colorectal Cancer Study Group
    • 10.1200/JCO.2005.03.033 1:CAS:528:DC%2BD2MXitl2gurw%3D 15718312
    • M Filipits G Pohl M Rudas O Dietze S Lax R Grill, et al. 2005 Clinical role of multidrug resistance protein 1 expression in chemotherapy resistance in early-stage breast cancer: the Austrian Breast and Colorectal Cancer Study Group J Clin Oncol. 23 1161 8 10.1200/JCO.2005.03.033 1:CAS:528:DC%2BD2MXitl2gurw%3D 15718312
    • (2005) J Clin Oncol. , vol.23 , pp. 1161-8
    • Filipits, M.1    Pohl, G.2    Rudas, M.3    Dietze, O.4    Lax, S.5    Grill, R.6
  • 7
    • 0037362355 scopus 로고    scopus 로고
    • ATP binding cassette transporters and drug resistance in breast cancer
    • 10.1677/erc.0.0100043 1:CAS:528:DC%2BD3sXksVahtLk%3D 12653670
    • F Leonessa R Clarke 2003 ATP binding cassette transporters and drug resistance in breast cancer Endocr Relat Cancer. 10 43 73 10.1677/erc.0.0100043 1:CAS:528:DC%2BD3sXksVahtLk%3D 12653670
    • (2003) Endocr Relat Cancer. , vol.10 , pp. 43-73
    • Leonessa, F.1    Clarke, R.2
  • 8
    • 6444228081 scopus 로고    scopus 로고
    • Multidrug resistance associated genes MRP1, MRP2 and MRP3 in primary and anthracycline exposed breast cancer
    • 1:CAS:528:DC%2BD2cXhtVSjsLvF 15517899
    • IF Faneyte PM Kristel MJ van de Vijver 2004 Multidrug resistance associated genes MRP1, MRP2 and MRP3 in primary and anthracycline exposed breast cancer Anticancer Res 24 2931 9 1:CAS:528:DC%2BD2cXhtVSjsLvF 15517899
    • (2004) Anticancer Res , vol.24 , pp. 2931-9
    • Faneyte, I.F.1    Kristel, P.M.2    Van De Vijver, M.J.3
  • 9
    • 0028244465 scopus 로고
    • Rapid acquisition of multicellular drug resistance after a single exposure of mammary tumor cells to antitumor alkylating agents
    • 10.1093/jnci/86.13.975 1:CAS:528:DyaK2cXmt1WhsL4%3D 8007019
    • CH Graham H Kobayashi KS Stankiewicz S Man SJ Kapitain RS Kerbel 1994 Rapid acquisition of multicellular drug resistance after a single exposure of mammary tumor cells to antitumor alkylating agents J Natl Cancer Inst. 86 975 82 10.1093/jnci/86.13.975 1:CAS:528:DyaK2cXmt1WhsL4%3D 8007019
    • (1994) J Natl Cancer Inst. , vol.86 , pp. 975-82
    • Graham, C.H.1    Kobayashi, H.2    Stankiewicz, K.S.3    Man, S.4    Kapitain, S.J.5    Kerbel, R.S.6
  • 10
    • 2442628298 scopus 로고    scopus 로고
    • Biochemical characterization of in vivo alkylating agent resistance of a murine EMT-6 mammary carcinoma. Implication for systemic involvement in the resistance phenotype
    • 1:CAS:528:DyaK1MXisFSquw%3D%3D 9923973
    • G Chen BA Teicher E Frei 1998 Biochemical characterization of in vivo alkylating agent resistance of a murine EMT-6 mammary carcinoma. Implication for systemic involvement in the resistance phenotype Cancer Biochem Biophys 16 139 55 1:CAS:528:DyaK1MXisFSquw%3D%3D 9923973
    • (1998) Cancer Biochem Biophys , vol.16 , pp. 139-55
    • Chen, G.1    Teicher, B.A.2    Frei, E.3
  • 11
    • 0025968103 scopus 로고
    • Glutathione diminishes the anti-tumour activity of 4- hydroperoxycyclophosphamide by stabilising its spontaneous breakdown to alkylating metabolites
    • 1:CAS:528:DyaK3MXhvF2hsrg%3D 1989664
    • FY Lee 1991 Glutathione diminishes the anti-tumour activity of 4-hydroperoxycyclophosphamide by stabilising its spontaneous breakdown to alkylating metabolites Br J Cancer 63 45 50 1:CAS:528:DyaK3MXhvF2hsrg%3D 1989664
    • (1991) Br J Cancer , vol.63 , pp. 45-50
    • Lee, F.Y.1
  • 12
    • 0029076803 scopus 로고
    • Identification of glutathione S-transferase as a determinant of 4-hydroperoxycyclophosphamide resistance in human breast cancer cells
    • 10.1016/0006-2952(95)00079-F 1:CAS:528:DyaK2MXmt1ShsLc%3D 7786310
    • G Chen DJ Waxman 1995 Identification of glutathione S-transferase as a determinant of 4-hydroperoxycyclophosphamide resistance in human breast cancer cells Biochem Pharmacol 49 1691 701 10.1016/0006-2952(95)00079-F 1:CAS:528:DyaK2MXmt1ShsLc%3D 7786310
    • (1995) Biochem Pharmacol , vol.49 , pp. 1691-701
    • Chen, G.1    Waxman, D.J.2
  • 13
    • 0036471128 scopus 로고    scopus 로고
    • Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues
    • 10.1042/0264-6021:3610497 1:CAS:528:DC%2BD38XhslOqsbY%3D 11802779
    • LQ Lai TM Tan 2002 Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues Biochem J 361 497 503 10.1042/0264-6021:3610497 1:CAS:528: DC%2BD38XhslOqsbY%3D 11802779
    • (2002) Biochem J , vol.361 , pp. 497-503
    • Lai, L.Q.1    Tan, T.M.2
  • 14
    • 33645825217 scopus 로고    scopus 로고
    • Substrate specificity of human ABCC4 (MRP4)-mediated cotransport of bile acids and reduced glutathione
    • 10.1152/ajpgi.00354.2005 1:CAS:528:DC%2BD28Xks1Slsb0%3D 16282361
    • M Rius J Hummel-Eisenbeiss AF Hofmann D Keppler 2006 Substrate specificity of human ABCC4 (MRP4)-mediated cotransport of bile acids and reduced glutathione Am J Physiol Gastrointest Liver Physiol. 290 G640 9 10.1152/ajpgi.00354.2005 1:CAS:528:DC%2BD28Xks1Slsb0%3D 16282361
    • (2006) Am J Physiol Gastrointest Liver Physiol. , vol.290 , pp. 640-9
    • Rius, M.1    Hummel-Eisenbeiss, J.2    Hofmann, A.F.3    Keppler, D.4
  • 15
    • 0023130372 scopus 로고
    • Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing
    • 1:CAS:528:DyaL2sXhsVyrtb0%3D 3802100
    • J Carmichael WG DeGraff AF Gazdar JD Minna JB Mitchell 1987 Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing Cancer Res 47 936 42 1:CAS:528:DyaL2sXhsVyrtb0%3D 3802100
    • (1987) Cancer Res , vol.47 , pp. 936-42
    • Carmichael, J.1    Degraff, W.G.2    Gazdar, A.F.3    Minna, J.D.4    Mitchell, J.B.5
  • 16
    • 0043132421 scopus 로고    scopus 로고
    • The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs
    • 10.1073/pnas.1033060100 1:CAS:528:DC%2BD3sXmtlyktrg%3D 12835412
    • G Reid P Wielinga N Zelcer I van der Heijden A Kuil M de Haas, et al. 2003 The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs Proc Natl Acad Sci USA 100 9244 9 10.1073/pnas.1033060100 1:CAS:528: DC%2BD3sXmtlyktrg%3D 12835412
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9244-9
    • Reid, G.1    Wielinga, P.2    Zelcer, N.3    Van Der Heijden, I.4    Kuil, A.5    De Haas, M.6
  • 17
    • 0042766881 scopus 로고    scopus 로고
    • Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane
    • 10.1053/jhep.2003.50331 1:CAS:528:DC%2BD3sXmvFSmtbk%3D 12883481
    • M Rius AT Nies J Hummel-Eisenbeiss G Jedlitschky D Keppler 2003 Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane Hepatology. 38 374 84 10.1053/jhep.2003. 50331 1:CAS:528:DC%2BD3sXmvFSmtbk%3D 12883481
    • (2003) Hepatology. , vol.38 , pp. 374-84
    • Rius, M.1    Nies, A.T.2    Hummel-Eisenbeiss, J.3    Jedlitschky, G.4    Keppler, D.5
  • 18
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2 - Δ \Δ Ct method
    • 10.1006/meth.2001.1262 1:CAS:528:DC%2BD38XhtFelt7s%3D 11846609
    • KJ Livak TD Schmittgen 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2 - Δ \Δ Ct method Methods 25 402 8 10.1006/meth.2001.1262 1:CAS:528:DC%2BD38XhtFelt7s%3D 11846609
    • (2001) Methods , vol.25 , pp. 402-8
    • Livak, K.J.1    Schmittgen, T.D.2
  • 19
    • 0038752694 scopus 로고    scopus 로고
    • Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5
    • 10.1124/mol.63.5.1094 1:CAS:528:DC%2BD3sXjt12lu7Y%3D 12695538
    • G Reid P Wielinga N Zelcer M De Haas L Van Deemter J Wijnholds, et al. 2003 Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5 Mol Pharmacol 63 1094 103 10.1124/mol.63.5.1094 1:CAS:528:DC%2BD3sXjt12lu7Y%3D 12695538
    • (2003) Mol Pharmacol , vol.63 , pp. 1094-103
    • Reid, G.1    Wielinga, P.2    Zelcer, N.3    De Haas, M.4    Van Deemter, L.5    Wijnholds, J.6
  • 20
    • 33645865553 scopus 로고    scopus 로고
    • Induction of hepatic transporters multidrug resistance-associated proteins (Mrp) 3 and 4 by clofibrate is regulated by peroxisome proliferator-activated receptor alpha
    • 10.1124/jpet.105.093765 1:CAS:528:DC%2BD28XktFamtLk%3D 16467456
    • JS Moffit LM Aleksunes JM Maher GL Scheffer CD Klaassen JE Manautou 2006 Induction of hepatic transporters multidrug resistance-associated proteins (Mrp) 3 and 4 by clofibrate is regulated by peroxisome proliferator-activated receptor alpha J Pharmacol Exp Ther. 317 537 45 10.1124/jpet.105.093765 1:CAS:528:DC%2BD28XktFamtLk%3D 16467456
    • (2006) J Pharmacol Exp Ther. , vol.317 , pp. 537-45
    • Moffit, J.S.1    Aleksunes, L.M.2    Maher, J.M.3    Scheffer, G.L.4    Klaassen, C.D.5    Manautou, J.E.6
  • 21
    • 30444441659 scopus 로고    scopus 로고
    • Metabolism and transport of oxzaphosphorines and the clinical implications
    • 10.1080/03602530500364023 1:CAS:528:DC%2BD28XmslWg 16393888
    • J Zhang Q Tian SY Chan SC Li S Zhou W Duan, et al. 2005 Metabolism and transport of oxzaphosphorines and the clinical implications Drug Metab Rev 37 611 703 10.1080/03602530500364023 1:CAS:528:DC%2BD28XmslWg 16393888
    • (2005) Drug Metab Rev , vol.37 , pp. 611-703
    • Zhang, J.1    Tian, Q.2    Chan, S.Y.3    Li, S.C.4    Zhou, S.5    Duan, W.6
  • 22
    • 18944406922 scopus 로고    scopus 로고
    • Drug sensitivity and drug resistance profiles of human intrahepatic cholangiocarcinoma cell lines
    • 1:CAS:528:DC%2BD2MXlslKitLo%3D 15884115
    • N Tepsiri L Chaturat B Sripa W Namwat S Wongkham V Bhudhisawasdi, et al. 2005 Drug sensitivity and drug resistance profiles of human intrahepatic cholangiocarcinoma cell lines World J Gastroenterol 11 2748 53 1:CAS:528:DC%2BD2MXlslKitLo%3D 15884115
    • (2005) World J Gastroenterol , vol.11 , pp. 2748-53
    • Tepsiri, N.1    Chaturat, L.2    Sripa, B.3    Namwat, W.4    Wongkham, S.5    Bhudhisawasdi, V.6
  • 23
    • 0037927606 scopus 로고    scopus 로고
    • Identification of domains participating in the substrate specificity and subcellular localization of the multidrug resistance proteins MRP1 and MRP2
    • 10.1074/jbc.M302868200 1:CAS:528:DC%2BD3sXksF2iurg%3D 12682044
    • T Konno T Ebihara K Hisaeda T Uchiumi T Nakamura T Shirakusa, et al. 2003 Identification of domains participating in the substrate specificity and subcellular localization of the multidrug resistance proteins MRP1 and MRP2 J Biol Chem. 278 22908 17 10.1074/jbc.M302868200 1:CAS:528:DC%2BD3sXksF2iurg%3D 12682044
    • (2003) J Biol Chem. , vol.278 , pp. 22908-17
    • Konno, T.1    Ebihara, T.2    Hisaeda, K.3    Uchiumi, T.4    Nakamura, T.5    Shirakusa, T.6
  • 24
    • 0025295106 scopus 로고
    • Combination chemotherapy with oral etoposide plus intravenous cyclophosphamide in liver metastases of breast cancer
    • 10.1097/00000421-199004000-00002 1:STN:280:DyaK3c7psF2msg%3D%3D 2316488
    • J Estape M Daniels N Vinolas P Santabarbara JJ Grau S Gardella 1990 Combination chemotherapy with oral etoposide plus intravenous cyclophosphamide in liver metastases of breast cancer Am J Clin Oncol 13 98 100 10.1097/00000421-199004000-00002 1:STN:280:DyaK3c7psF2msg%3D%3D 2316488
    • (1990) Am J Clin Oncol , vol.13 , pp. 98-100
    • Estape, J.1    Daniels, M.2    Vinolas, N.3    Santabarbara, P.4    Grau, J.J.5    Gardella, S.6
  • 25
    • 0033724658 scopus 로고    scopus 로고
    • The effect of rifampin treatment on intestinal expression of human MRP transporters
    • 1:CAS:528:DC%2BD3cXosFyhsrY%3D 11073816
    • MF Fromm HM Kauffmann P Fritz O Burk HK Kroemer RW Warzok, et al. 2000 The effect of rifampin treatment on intestinal expression of human MRP transporters Am J Pathol 157 1575 80 1:CAS:528:DC%2BD3cXosFyhsrY%3D 11073816
    • (2000) Am J Pathol , vol.157 , pp. 1575-80
    • Fromm, M.F.1    Kauffmann, H.M.2    Fritz, P.3    Burk, O.4    Kroemer, H.K.5    Warzok, R.W.6
  • 26
    • 0035977844 scopus 로고    scopus 로고
    • Up-regulation of transporters of the MRP family by drugs and toxins
    • 10.1016/S0378-4274(01)00306-X 1:CAS:528:DC%2BD3MXivFejs7k%3D 11323161
    • D Schrenk PR Baus N Ermel C Klein B Vorderstemann HM Kauffmann 2001 Up-regulation of transporters of the MRP family by drugs and toxins Toxicol Lett 120 51 7 10.1016/S0378-4274(01)00306-X 1:CAS:528:DC%2BD3MXivFejs7k%3D 11323161
    • (2001) Toxicol Lett , vol.120 , pp. 51-7
    • Schrenk, D.1    Baus, P.R.2    Ermel, N.3    Klein, C.4    Vorderstemann, B.5    Kauffmann, H.M.6
  • 27
    • 0142150021 scopus 로고    scopus 로고
    • Induction of ABCC3 (MRP3) by pregnane X receptor activators
    • 10.1124/dmd.31.11.1296 1:CAS:528:DC%2BD3sXosV2qtb0%3D 14570758
    • S Teng V Jekerle M Piquette-Miller 2003 Induction of ABCC3 (MRP3) by pregnane X receptor activators Drug Metab Dispos 31 1296 9 10.1124/dmd.31.11. 1296 1:CAS:528:DC%2BD3sXosV2qtb0%3D 14570758
    • (2003) Drug Metab Dispos , vol.31 , pp. 1296-9
    • Teng, S.1    Jekerle, V.2    Piquette-Miller, M.3
  • 28
    • 1642422386 scopus 로고    scopus 로고
    • Rat multidrug resistance protein 4 (Mrp4, Abcc4): Molecular cloning, organ distribution, postnatal renal expression, and chemical inducibility
    • 10.1016/j.bbrc.2004.03.014 1:CAS:528:DC%2BD2cXisVKmsbc%3D 15047146
    • C Chen CD Klaassen 2004 Rat multidrug resistance protein 4 (Mrp4, Abcc4): molecular cloning, organ distribution, postnatal renal expression, and chemical inducibility Biochem Biophys Res Commun 317 46 53 10.1016/j.bbrc.2004.03.014 1:CAS:528:DC%2BD2cXisVKmsbc%3D 15047146
    • (2004) Biochem Biophys Res Commun , vol.317 , pp. 46-53
    • Chen, C.1    Klaassen, C.D.2
  • 29
    • 22344433760 scopus 로고    scopus 로고
    • Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver
    • 10.1124/dmd.105.003798 1:CAS:528:DC%2BD2MXlslWqs7c%3D 15833929
    • JM Maher X Cheng AL Slitt MZ Dieter CD Klaassen 2005 Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver Drug Metab Dispos 33 956 62 10.1124/dmd.105.003798 1:CAS:528:DC%2BD2MXlslWqs7c%3D 15833929
    • (2005) Drug Metab Dispos , vol.33 , pp. 956-62
    • Maher, J.M.1    Cheng, X.2    Slitt, A.L.3    Dieter, M.Z.4    Klaassen, C.D.5
  • 30
    • 2542440464 scopus 로고    scopus 로고
    • Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice
    • 10.1074/jbc.M314111200 1:CAS:528:DC%2BD2cXjvF2rsbs%3D 15004017
    • M Assem EG Schuetz M Leggas D Sun K Yasuda G Reid, et al. 2004 Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice J Biol Chem. 279 22250 7 10.1074/jbc.M314111200 1:CAS:528:DC%2BD2cXjvF2rsbs%3D 15004017
    • (2004) J Biol Chem. , vol.279 , pp. 22250-7
    • Assem, M.1    Schuetz, E.G.2    Leggas, M.3    Sun, D.4    Yasuda, K.5    Reid, G.6
  • 31
    • 56649113047 scopus 로고    scopus 로고
    • Nrf2- and PPAR alpha-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid
    • 10.1093/toxsci/kfn177 1:CAS:528:DC%2BD1cXhtlGht7vI 18757529
    • JM Maher LM Aleksunes MZ Dieter Y Tanaka JM Peters JE Manautou, et al. 2008 Nrf2- and PPAR alpha-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid Toxicol Sci. 106 319 28 10.1093/toxsci/kfn177 1:CAS:528:DC%2BD1cXhtlGht7vI 18757529
    • (2008) Toxicol Sci. , vol.106 , pp. 319-28
    • Maher, J.M.1    Aleksunes, L.M.2    Dieter, M.Z.3    Tanaka, Y.4    Peters, J.M.5    Manautou, J.E.6
  • 32
    • 0030454445 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Structures and function
    • 10.1111/j.1749-6632.1996.tb18620.x 1:CAS:528:DyaK2sXhtVehur8%3D 8993548
    • JD Tugwood TC Aldridge KG Lambe N Macdonald NJ Woodyatt 1996 Peroxisome proliferator-activated receptors: structures and function Ann N Y Acad Sci 804 252 65 10.1111/j.1749-6632.1996.tb18620.x 1:CAS:528:DyaK2sXhtVehur8%3D 8993548
    • (1996) Ann N y Acad Sci , vol.804 , pp. 252-65
    • Tugwood, J.D.1    Aldridge, T.C.2    Lambe, K.G.3    MacDonald, N.4    Woodyatt, N.J.5
  • 33
    • 2342428577 scopus 로고    scopus 로고
    • Characterization of the species-specificity of peroxisome proliferators in rat and human hepatocytes
    • 10.1093/toxsci/kfh071 1:CAS:528:DC%2BD2cXjt1aqsbY%3D 14976357
    • M Ammerschlaeger J Beigel KU Klein SO Mueller 2004 Characterization of the species-specificity of peroxisome proliferators in rat and human hepatocytes Toxicol Sci. 78 229 40 10.1093/toxsci/kfh071 1:CAS:528:DC%2BD2cXjt1aqsbY%3D 14976357
    • (2004) Toxicol Sci. , vol.78 , pp. 229-40
    • Ammerschlaeger, M.1    Beigel, J.2    Klein, K.U.3    Mueller, S.O.4
  • 34
    • 34748840488 scopus 로고    scopus 로고
    • Induction of hepatobiliary efflux transporters in acetaminophen-induced acute liver failure cases
    • 10.1124/dmd.107.016170 1:CAS:528:DC%2BD2sXhtFantr7O
    • SN Barnes LM Aleksunes L Augustine GL Scheffer MJ Goedken AB Jakowski, et al. 2007 Induction of hepatobiliary efflux transporters in acetaminophen- induced acute liver failure cases Drug Metab Disposit. 35 1963 9 10.1124/dmd.107.016170 1:CAS:528:DC%2BD2sXhtFantr7O
    • (2007) Drug Metab Disposit. , vol.35 , pp. 1963-9
    • Barnes, S.N.1    Aleksunes, L.M.2    Augustine, L.3    Scheffer, G.L.4    Goedken, M.J.5    Jakowski, A.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.