메뉴 건너뛰기




Volumn 12, Issue 6, 2010, Pages 395-400

Breast cancer stem cell hypothesis: Clinical relevance (answering breast cancer clinical features)

Author keywords

Asymmetric division; Breast cancer; Cancer stem cell; Hedgehog; Mammosphere; Notch; Self renewal; Wnt

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE ISOENZYME 1; BRCA1 PROTEIN; BREAST CANCER RESISTANCE PROTEIN; CD24 ANTIGEN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ETAMSYLATE; EVEROLIMUS; HERMES ANTIGEN; LAPATINIB; PROTEINASE INHIBITOR; TEMSIROLIMUS; UNCLASSIFIED DRUG;

EID: 77955943275     PISSN: 1699048X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12094-010-0526-4     Document Type: Review
Times cited : (3)

References (35)
  • 1
    • 33644560281 scopus 로고    scopus 로고
    • Cancer stem cells: An old idea - A paradigm shift
    • Wicha MS, Liu S, Dontu G (2006) Cancer stem cells: an old idea - a paradigm shift. Cancer Res 66:1883-1890
    • (2006) Cancer Res , vol.66 , pp. 1883-1890
    • Wicha, M.S.1    Liu, S.2    Dontu, G.3
  • 2
    • 70349123829 scopus 로고    scopus 로고
    • The tumor suppressor p53 regulates polarity of selfrenewing divisions in mammary stem cells
    • Cicalese A, Bonizzi G, Pasi CE et al (2009) The tumor suppressor p53 regulates polarity of selfrenewing divisions in mammary stem cells. Cell 138:1083-1095
    • (2009) Cell , vol.138 , pp. 1083-1095
    • Cicalese, A.1    Bonizzi, G.2    Pasi, C.E.3
  • 3
    • 30144432901 scopus 로고    scopus 로고
    • Purification and unique properties of mammary epithelial stem cells
    • Stingl J, Eirew P, Ricketson I et al (2006) Purification and unique properties of mammary epithelial stem cells. Nature 439:993-997
    • (2006) Nature , vol.439 , pp. 993-997
    • Stingl, J.1    Eirew, P.2    Ricketson, I.3
  • 4
    • 0037948854 scopus 로고    scopus 로고
    • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    • Dontu G, Abdallah WM, Foley JM et al (2003) In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 17:1253-1270
    • (2003) Genes Dev , vol.17 , pp. 1253-1270
    • Dontu, G.1    Abdallah, W.M.2    Foley, J.M.3
  • 5
    • 34247117277 scopus 로고    scopus 로고
    • Evidence for a stem cell hierarchy in the adult human breast
    • Villadsen R, Fridriksdottir AJ, Ronnov-Jessen L et al (2007) Evidence for a stem cell hierarchy in the adult human breast. J Cell Biol 177:87-101
    • (2007) J Cell Biol , vol.177 , pp. 87-101
    • Villadsen, R.1    Fridriksdottir, A.J.2    Ronnov-Jessen, L.3
  • 6
    • 30144433093 scopus 로고    scopus 로고
    • Generation of a functional mammary gland from a single stem cell
    • Shackleton M, Vaillant F, Simpson KJ et al (2006) Generation of a functional mammary gland from a single stem cell. Nature 439:84-88
    • (2006) Nature , vol.439 , pp. 84-88
    • Shackleton, M.1    Vaillant, F.2    Simpson, K.J.3
  • 8
    • 0037948854 scopus 로고    scopus 로고
    • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    • Dontu G, Abdallah WM, Foley JM et al (2003) In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 17:1253-1270
    • (2003) Genes Dev , vol.17 , pp. 1253-1270
    • Dontu, G.1    Abdallah, W.M.2    Foley, J.M.3
  • 9
    • 33745728170 scopus 로고    scopus 로고
    • Hedgehog signalling and BMI-1 regulate self-renewal of normal and malignant human mammary stem cells
    • Liu S, Dontu G, Mantle ID et al (2006) Hedgehog signalling and BMI-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res 66:6063-6071
    • (2006) Cancer Res , vol.66 , pp. 6063-6071
    • Liu, S.1    Dontu, G.2    Mantle, I.D.3
  • 10
    • 50849090608 scopus 로고    scopus 로고
    • The emerging picture of human breast cancer: As a stem cell-based disease
    • César Cobaleda C, Cruz JJ, González-Sarmiento R et al (2008) The emerging picture of human breast cancer: as a stem cell-based disease. StemCell Rev 4:67-79
    • (2008) StemCell Rev , vol.4 , pp. 67-79
    • César Cobaleda, C.1    Cruz, J.J.2    González-Sarmiento, R.3
  • 11
    • 34648821257 scopus 로고    scopus 로고
    • Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis
    • Stingl J, Caldas C (2007) Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis. Nat Rev Cancer 7:791-799
    • (2007) Nat Rev Cancer , vol.7 , pp. 791-799
    • Stingl, J.1    Caldas, C.2
  • 12
    • 9144269759 scopus 로고    scopus 로고
    • Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells
    • Li Y, Welm B, Podsypanina K et al (2003) Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells. Proc Natl Acad Sci U S A 100:15853-15858
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 15853-15858
    • Li, Y.1    Welm, B.2    Podsypanina, K.3
  • 13
    • 0020328219 scopus 로고
    • Differentiation of the mammary gland and susceptibility to carcinogenesis
    • Russo J, Tay LK, Russo IH (1982) Differentiation of the mammary gland and susceptibility to carcinogenesis. Breast Cancer Res Treat 2:5-73
    • (1982) Breast Cancer Res Treat , vol.2 , pp. 5-73
    • Russo, J.1    Tay, L.K.2    Russo, I.H.3
  • 14
  • 15
    • 0037380886 scopus 로고    scopus 로고
    • Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia
    • Holst CR, Nuovo GJ, Esteller M et al (2003) Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia. Cancer Res 63:1596-1601
    • (2003) Cancer Res , vol.63 , pp. 1596-1601
    • Holst, C.R.1    Nuovo, G.J.2    Esteller, M.3
  • 16
    • 36248991811 scopus 로고    scopus 로고
    • Breast cancer stem cells: A case of mistaken identity?
    • Polyak K (2007) Breast cancer stem cells: a case of mistaken identity? Stem Cell Rev 3(2):107-109
    • (2007) Stem Cell Rev , vol.3 , Issue.2 , pp. 107-109
    • Polyak, K.1
  • 17
    • 21344454219 scopus 로고    scopus 로고
    • Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
    • Ponti D, Costa A, Zaffaroni N et al (2005) Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res 65:5506-5511
    • (2005) Cancer Res , vol.65 , pp. 5506-5511
    • Ponti, D.1    Costa, A.2    Zaffaroni, N.3
  • 18
    • 0036154828 scopus 로고    scopus 로고
    • The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells
    • Kim M, Turnquist H, Jackson J et al (2002) The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells. Clin Cancer Res 8:22-28
    • (2002) Clin Cancer Res , vol.8 , pp. 22-28
    • Kim, M.1    Turnquist, H.2    Jackson, J.3
  • 19
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
    • Ginestier C, Hur MH, Charafe-Jauffret E et al (2007) ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1:555-567
    • (2007) Cell Stem Cell , vol.1 , pp. 555-567
    • Ginestier, C.1    Hur, M.H.2    Charafe-Jauffret, E.3
  • 21
    • 73149110562 scopus 로고    scopus 로고
    • Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
    • Pece S,Tosoni D, Confalonieri S et al (2010) Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell 140:62-73
    • (2010) Cell , vol.140 , pp. 62-73
    • Pece Stosoni, D.1    Confalonieri, S.2
  • 22
    • 0035967892 scopus 로고    scopus 로고
    • The evolving concept of a stem cell: Entity or function?
    • Blau HM, Brazelton TR, Weimann JM (2001) The evolving concept of a stem cell: entity or function? Cell 105:829-841
    • (2001) Cell , vol.105 , pp. 829-841
    • Blau, H.M.1    Brazelton, T.R.2    Weimann, J.M.3
  • 24
    • 44049100934 scopus 로고    scopus 로고
    • Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
    • Li X, Lewis MT, Huang J et al (2008) Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst 100(9):67
    • (2008) J Natl Cancer Inst , vol.100 , Issue.9 , pp. 67
    • Li, X.1    Lewis, M.T.2    Huang, J.3
  • 25
    • 0027932138 scopus 로고
    • Oxazaphosphorine-specific resistance in human MCF-7 breast carcinoma cell lines expressing transfected rat class 3 aldehyde dehydrogenase
    • Bunting KD, Lindahl R, Townsend AJ (1994) Oxazaphosphorine-specific resistance in human MCF-7 breast carcinoma cell lines expressing transfected rat class 3 aldehyde dehydrogenase. J Biol Chem 269:23197-23203
    • (1994) J Biol Chem , vol.269 , pp. 23197-23203
    • Bunting, K.D.1    Lindahl, R.2    Townsend, A.J.3
  • 26
    • 33845904383 scopus 로고    scopus 로고
    • The response of CD24(-/low)/CD44+ breast cancerinitiating cells to radiation
    • Phillips TM, McBride WH, Pajonk F (2006) The response of CD24(-/low)/CD44+ breast cancerinitiating cells to radiation. J Natl Cancer Inst 98:1777-1785
    • (2006) J Natl Cancer Inst , vol.98 , pp. 1777-1785
    • Phillips, T.M.1    McBride, W.H.2    Pajonk, F.3
  • 27
    • 67649884727 scopus 로고    scopus 로고
    • Stem cell marker aldehyde dehydrogenase 1-positive breast cancers are characterized by negative estrogen receptor, positive human epidermal growth factor receptor type 2, and high Ki67 expression.
    • Koji Morimoto, Seung Jin Kim, Tomonori Tanei et al (2009) Stem cell marker aldehyde dehydrogenase 1-positive breast cancers are characterized by negative estrogen receptor, positive human epidermal growth factor receptor type 2, and high Ki67 expression. Cancer Sci 100:1062-1068
    • (2009) Cancer Sci , vol.100 , pp. 1062-1068
    • Morimoto, K.1    Jin Kim, S.2    Tanei, T.3
  • 28
    • 77955773149 scopus 로고    scopus 로고
    • Prognostic impact of ALDH1 in breast cancer: A story of stem cells and tumor microenvironment
    • DOI 10.1007/s10549-009-0619-623
    • Resetkova E, Reis-Filho J, Jain R et al (2009) Prognostic impact of ALDH1 in breast cancer: a story of stem cells and tumor microenvironment. Breast Cancer Res Treat DOI 10.1007/s10549-009-0619-623
    • (2009) Breast Cancer Res Treat
    • Resetkova, E.1    Reis-Filho, J.2    Jain, R.3
  • 29
    • 67449113764 scopus 로고    scopus 로고
    • Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential paclitaxel and epirubicin-based chemotherapy for breast cancers
    • Tomonori Tanei, Koji Morimoto, Kenzo Shimazu et al (2009) Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential paclitaxel and epirubicin-based chemotherapy for breast cancers. Clin Cancer Res 15(12):4234-4241
    • (2009) Clin Cancer Res , vol.15 , Issue.12 , pp. 4234-4241
    • Tanei, T.1    Morimoto, K.2    Shimazu, K.3
  • 30
    • 54049096261 scopus 로고    scopus 로고
    • HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
    • Korkaya H, Paulson A, Iovino F et al (2008) HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. Oncogene 27:6120-6130
    • (2008) Oncogene , vol.27 , pp. 6120-6130
    • Korkaya, H.1    Paulson, A.2    Iovino, F.3
  • 31
    • 44049100934 scopus 로고    scopus 로고
    • Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
    • Li X, Lewis MT, Huang J et al (2008) Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst 100(9):672
    • (2008) J Natl Cancer Inst , vol.100 , Issue.9 , pp. 672
    • Li, X.1    Lewis, M.T.2    Huang, J.3
  • 32
    • 0242456129 scopus 로고    scopus 로고
    • Notch signalling as a therapeutic target in cancer: A new approach to the development of cell fate modifying agents
    • Nickoloff BJ, Osborne BA, Miele L (2003) Notch signalling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. Oncogene 22:6598-6608
    • (2003) Oncogene , vol.22 , pp. 6598-6608
    • Nickoloff, B.J.1    Osborne, B.A.2    Miele, L.3
  • 33
    • 34547693211 scopus 로고    scopus 로고
    • Hedgehog signaling in mammary gland development and breast cancer
    • Hatsell S, Frost AR (2007) Hedgehog signaling in mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia 12:163-173
    • (2007) J Mammary Gland Biol Neoplasia , vol.12 , pp. 163-173
    • Hatsell, S.1    Frost, A.R.2
  • 34
    • 37549020704 scopus 로고    scopus 로고
    • Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair
    • Saal LH, Gruvberger-Saal SK, Persson C et al (2008) Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair. Nat Genet 40:102-107
    • (2008) Nat Genet , vol.40 , pp. 102-107
    • Saal, L.H.1    Gruvberger-Saal, S.K.2    Persson, C.3
  • 35
    • 36549009637 scopus 로고    scopus 로고
    • Restoration of p53 to limit tumor growth
    • Wang W, El-Deiry WS (2008) Restoration of p53 to limit tumor growth. Curr Opin Oncol 20:90-96
    • (2008) Curr Opin Oncol , vol.20 , pp. 90-96
    • Wang, W.1    El-Deiry, W.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.