Biotin synthesis begins by hijacking the fatty acid synthetic pathway

Nature Chemical Biology

Volumn 6, Issue 9, 2010, Pages 682-688

  Lin, Steven ^a   Hanson, Ryan E ^a   Cronan, John E ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CARRIER PROTEIN; BIOTIN; BIOTIN C; BIOTIN H; CARBOXYL GROUP; DETHIOBIOTIN; FATTY ACID; GLUTARIC ACID; MALONIC ACID; MALONYL COENZYME A; METHANOL; METHYLTRANSFERASE; PIMELIC ACID; THIOESTER; UNCLASSIFIED DRUG; ESTER; FATTY ACID SYNTHASE INHIBITOR;

ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BIOSYNTHESIS; CONTROLLED STUDY; ESCHERICHIA COLI; HYDROLYSIS; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DOSE RESPONSE; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; METABOLISM; METHYLATION; VIBRIO;

ESCHERICHIA COLI;

ACYL CARRIER PROTEIN; BIOTIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; ESTERS; FATTY ACID SYNTHESIS INHIBITORS; FATTY ACIDS; HYDROLYSIS; METHANOL; METHYLATION; SUBSTRATE SPECIFICITY; VIBRIO;

EID: 77955927354     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.420     Document Type: Article

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