Role of heparan sulfates and glycosphingolipids in the pore formation of basic polypeptides of cobra cardiotoxin

Advances in Experimental Medicine and Biology

Volumn 677, Issue , 2010, Pages 143-149

  Wu, Wen Guey ^a   Tjong, Siu Cin ^b   Wu, Po Long ^b   Kuo, Je Hung ^b   Wu, Karen ^b  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

COBROTOXIN; COBROTOXIN A3; GLYCOSPHINGOLIPID; HEPARAN SULFATE; POLYPEPTIDE; SULFATIDE; UNCLASSIFIED DRUG; PORE FORMING CYTOTOXIC PROTEIN; SPHINGOLIPID;

CHANNEL GATING; CONFORMATIONAL TRANSITION; DIMERIZATION; ENDOCYTOSIS; EXTRACELLULAR MATRIX; HYDROPHOBICITY; INTERNALIZATION; LIPID BILAYER; LIPID RAFT; LIPID VESICLE; MOLECULAR DOCKING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STABILITY; REVIEW; TOXIN STRUCTURE; ANIMAL; CELL MEMBRANE; CHEMISTRY; HEART ARREST; HUMAN; METABOLISM; NECROSIS; SNAKE;

ANIMALS; COBRA; COBRA CARDIOTOXIN PROTEINS; HEART ARREST; HEPARITIN SULFATE; HUMANS; LIPID BILAYERS; MEMBRANE MICRODOMAINS; NECROSIS; PORE FORMING CYTOTOXIC PROTEINS; SPHINGOLIPIDS;

EID: 77955884926     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-6327-7_12     Document Type: Review

References (33)

1. Lindahl U. Heparan sulfate-protein interactions-a concept for drug design? Thromb Haemost 2007; 98:109-115. (Pubitemid 47074185)
2. Murphy JW, Cho Y, Sachpatzidis A et al. Structural and functional basis of CXCL12 (stromal cell-derived factor-1 alpha) binding to heparin. J Biol Chem 2007; 282:10018-10027. (Pubitemid 47104591)
3. Schenauer MR, Yu Y, Sweeney MD et al. CCR2 chemokines bind selectively to acetylated heparan sulfate octasaccharides. J Biol Chem 2007; 282:25182-25188. (Pubitemid 47372809)
4. Laguri C, Arenzana-Seisdedos F, Lortat-Jacob H. Relationships between glycosaminoglycan and receptor binding sites in chemokines-the CXCL12 example. Carbohydr Res 2008; 343:2018-2023.
5. Taylor KR, Gallo RL. Glycosaminoglycans and their proteoglycans: host-associated molecular patterns for initiation and modulation of inflammation. FASEB J 2006; 20:9-22. (Pubitemid 43100470)
6. Lajoie P, Goetz JG, Dennis JW et al. Lattices, rafts and scaffolds: domain regulation of receptor signaling at the plasma membrane. J Cell Biochem 2009; 185.381-385.
7. Holthuis JC, Levine TP. Lipid traffic: floppy drives and a superhighway. Nat Rev Mol Cell Biol 2005; 6:209-220. (Pubitemid 40314922)
8. Sillence DJ. New insights into glycosphingolipid functions-storage, lipid rafts and translocators. Int Rev Cytol 2007; 262:151-189. (Pubitemid 47031308)
9. Eggeling C, Ringemann C, Medda R et al. Direct observation of the nanoscale dynamics of membrane lipids in a living cell. Nature 2009; 457:1159-1163.
10. Gilbert RJC, Jimenez JL, Chen S et al. Two structural transitions in membrane pore formation by pneumolysin, the pore-forming toxin of Streptococcus pneumonia. Cell 1999; 97:647-655. (Pubitemid 29256967)
11. Walz T. How cholesterol-dependent cytolysins bite holes into membranes. Mol Cell 2005; 18:393-394. (Pubitemid 40704752)
12. Tilley SJ, Orlova EV, Gilbert RJC et al. Structural basis of pore formation by the bacterial toxin pneumolysin. Cell 2005; 121:247-256. (Pubitemid 40546392)
13. Taylor K, Barran PE, Dorin JR. Structure-activity relationships in beta-defensin peptides. Biopolymers 2008; 90:1-7.
14. Aerts AM, François IE, Cammue BP et al. The mode of antifungal action of plant, insect and human defensins. Cell Mol Life Sci 2008; 65:2069-2079.
15. Chien KY, Chiang CM, Hseu YC et al. Two distinct types of cardiotoxin as revealed by the structure and activity relationship of their interaction with zwitterionic phospholipid dispersions. J Biol Chem 1994; 269:14473-14483.
16. Efremov RG, Volynsky PE, Nolde DE et al. Interaction of cardiotoxins with membranes: a molecular modeling study. Biophys J 2002; 83:144-53. (Pubitemid 34694727)
17. Lai MK, Wen CY, Lee CY. Local lesions1 caused by cardiotoxin isolated from Formosan cobra venom. J Formosan Med Assoc 1972; 71:328-332.
18. Hider RC, Khader F. Biochemical and pharmacological properties of cardiotoxins isolated from cobra venom. Toxicon 1982; 20:175-179. (Pubitemid 12160514)
19. Sun JJ, Walker MJ. Actions of cardiotoxins from the southern Chinese cobra (Naja naja atra) on rat cardiac tissue. Toxicon 1986; 24:233-245. (Pubitemid 16140095)
20. Dufton MJ, Hider RC. Structure and pharmacology of elapid cytotoxins. Pharmacol Ther. 1988; 36:1-40. (Pubitemid 18001621)
21. Fletcher JE, Jiang MH. Possible mechanisms of action of cobra snake venom cardiotoxins and bee venom melittin. Toxicon 1993; 31:669-695.
22. Lee SC, Guan HH, Wang CH. Structural basis of citrate-dependent and heparin sulfate-mediated cell surface retention of cobra cardiotoxin A3. J Biol Chem 2005; 280:9567-9577.
23. 3 integrin and inhibit bone resorption. Identification of cardiotoxins as nonRGD integrin-binding proteins of the Ly-6 family. J Biol Chem 2006; 281:7937-7945.
24. Wang CH, Liu JH, Lee SC et al. Glycosphingolipid-facilitated membrane insertion and internalization of cobra cardiotoxin. J Biol Chem 2006; 281:656-667.
25. Tjong SC, Chen TS, Huang WN et al. Structures of heparin-derived tetrasaccharide bound to cobra cardiotoxins: Heparin binding at a single protein site with diverse side chain interactions. Biochemistry 2007; 46:9941-9952.
26. Vyas KA, Patel HM, Vyas AA et al. Glycosaminoglycans bind to homologous cardiotoxins with different specificity. Biochemistry 1998; 37:4527-4534 (Pubitemid 28217171)
27. Schlessinger J, Plotnikov AN, Ibrahimi OA et al. Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization. Mol Cell 2000; 6:43-50.
28. Sue SC, Chien KY, Huang WN et al. Heparin binding stabilizes the membrane-bound form of cobra cardiotoxin. J Biol Chem 2002; 277:2666-2673.
29. Tjong SC, Wu PL, Wang CM et al. Role of glycosphingolipid conformational change in membrane pore forming activity of cobra cardiotoxin. Biochemistry 2007; 46:12111-12123.
30. Leontiadou H, Mark AE, Marrink SJ. Antimicrobial peptides in action. J Am Chem Soc 2006; 128:12156-12161. (Pubitemid 44413847)
31. Melo MN, Ferre R, Castanho MA. Antimicrobial peptides: linking partition, activity and high membrane-bound concentrations. Nat Rev Microbiol 2009; 7:245-250.
32. Dowhan W, Bogdanov M. Lipid-dependent membrane protein topogenesis. Annu Rev Biochem 2009; 78:5.1-5.26.
33. Idone V, Tam C, Goss JW et al. Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis. J Cell Biol 2008; 180:905-914. (Pubitemid 351398418)