-
1
-
-
0016332555
-
An animal model for the ketogenic diet
-
Appleton D.B., DeVivo D.C. An animal model for the ketogenic diet. Epilepsia 1974, 15:211-227.
-
(1974)
Epilepsia
, vol.15
, pp. 211-227
-
-
Appleton, D.B.1
DeVivo, D.C.2
-
2
-
-
33746848935
-
Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet
-
Bough K.J., Wetherington J., Hassel B., Pare J.F., Gawryluk J.W., Greene J.G., Shaw R., Smith Y., Geiger J.D., Dingledine R.J. Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet. Ann. Neurol. 2006, 60:223-235.
-
(2006)
Ann. Neurol.
, vol.60
, pp. 223-235
-
-
Bough, K.J.1
Wetherington, J.2
Hassel, B.3
Pare, J.F.4
Gawryluk, J.W.5
Greene, J.G.6
Shaw, R.7
Smith, Y.8
Geiger, J.D.9
Dingledine, R.J.10
-
3
-
-
34347242465
-
Mitochondria are a major source of paraquat-induced reactive oxygen species production in the brain
-
Castello P.R., Drechsel D.A., Patel M. Mitochondria are a major source of paraquat-induced reactive oxygen species production in the brain. J. Biol. Chem. 2007, 282:14186-14193.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 14186-14193
-
-
Castello, P.R.1
Drechsel, D.A.2
Patel, M.3
-
4
-
-
29644437160
-
4-Hydroxynonenal induces adaptive response and enhances PC12 cell tolerance primarily through induction of thioredoxin reductase 1 via activation of Nrf2
-
Chen Z.H., Saito Y., Yoshida Y., Sekine A., Noguchi N., Niki E. 4-Hydroxynonenal induces adaptive response and enhances PC12 cell tolerance primarily through induction of thioredoxin reductase 1 via activation of Nrf2. J. Biol. Chem. 2005, 280:41921-41927.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 41921-41927
-
-
Chen, Z.H.1
Saito, Y.2
Yoshida, Y.3
Sekine, A.4
Noguchi, N.5
Niki, E.6
-
5
-
-
33748313433
-
5-Methoxy-1, 2-dimethyl-3-[(4-nitrophenoxy)methyl]indole-4, 7-dione, a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1, exhibits activity against human pancreatic cancer in vitro and in vivo
-
Dehn D.L., Siegel D., Zafar K.S., Reigan P., Swann E., Moody C.J., Ross D. 5-Methoxy-1, 2-dimethyl-3-[(4-nitrophenoxy)methyl]indole-4, 7-dione, a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1, exhibits activity against human pancreatic cancer in vitro and in vivo. Mol. Cancer Ther. 2006, 5:1702-1709.
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 1702-1709
-
-
Dehn, D.L.1
Siegel, D.2
Zafar, K.S.3
Reigan, P.4
Swann, E.5
Moody, C.J.6
Ross, D.7
-
6
-
-
31344444853
-
+channel activity
-
+channel activity. Free Radic. Biol. Med. 2006, 40:469-479.
-
(2006)
Free Radic. Biol. Med.
, vol.40
, pp. 469-479
-
-
Facundo, H.T.1
Carreira, R.S.2
de Paula, J.G.3
Santos, C.C.4
Ferranti, R.5
Laurindo, F.R.6
Kowaltowski, A.J.7
-
7
-
-
2342613543
-
Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice
-
Goldring C.E., Kitteringham N.R., Elsby R., Randle L.E., Clement Y.N., Williams D.P., McMahon M., Hayes J.D., Itoh K., Yamamoto M., Park B.K. Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice. Hepatology 2004, 39:1267-1276.
-
(2004)
Hepatology
, vol.39
, pp. 1267-1276
-
-
Goldring, C.E.1
Kitteringham, N.R.2
Elsby, R.3
Randle, L.E.4
Clement, Y.N.5
Williams, D.P.6
McMahon, M.7
Hayes, J.D.8
Itoh, K.9
Yamamoto, M.10
Park, B.K.11
-
8
-
-
48249143179
-
The ketogenic diet increases mitochondrial glutathione levels
-
Jarrett S.G., Milder J.B., Liang L.P., Patel M. The ketogenic diet increases mitochondrial glutathione levels. J. Neurochem. 2008, 106:1044-1051.
-
(2008)
J. Neurochem.
, vol.106
, pp. 1044-1051
-
-
Jarrett, S.G.1
Milder, J.B.2
Liang, L.P.3
Patel, M.4
-
9
-
-
85047681405
-
Effects of fasting on tissue contents of coenzyme A and related intermediates in rats
-
Jenniskens F.A., Jopperi-Davis K.S., Walters L.C., Schorr E.N., Rogers L.K., Welty S.E., Smith C.V. Effects of fasting on tissue contents of coenzyme A and related intermediates in rats. Pediatr. Res. 2002, 52:437-442.
-
(2002)
Pediatr. Res.
, vol.52
, pp. 437-442
-
-
Jenniskens, F.A.1
Jopperi-Davis, K.S.2
Walters, L.C.3
Schorr, E.N.4
Rogers, L.K.5
Welty, S.E.6
Smith, C.V.7
-
10
-
-
33344469643
-
Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1
-
Kobayashi A., Kang M.I., Watai Y., Tong K.I., Shibata T., Uchida K., Yamamoto M. Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1. Mol. Cell. Biol. 2006, 26:221-229.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 221-229
-
-
Kobayashi, A.1
Kang, M.I.2
Watai, Y.3
Tong, K.I.4
Shibata, T.5
Uchida, K.6
Yamamoto, M.7
-
11
-
-
3543008924
-
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
-
Kobayashi A., Kang M.I., Okawa H., Ohtsuji M., Zenke Y., Chiba T., Igarashi K., Yamamoto M. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol. Cell. Biol. 2004, 24:7130-7139.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7130-7139
-
-
Kobayashi, A.1
Kang, M.I.2
Okawa, H.3
Ohtsuji, M.4
Zenke, Y.5
Chiba, T.6
Igarashi, K.7
Yamamoto, M.8
-
12
-
-
38649139139
-
When do seizures usually improve with the ketogenic diet?
-
Kossoff E.H., Laux L.C., Blackford R., Morrison P.F., Pyzik P.L., Hamdy R.M., Turner Z., Nordli D.R. When do seizures usually improve with the ketogenic diet?. Epilepsia 2008, 49:329-333.
-
(2008)
Epilepsia
, vol.49
, pp. 329-333
-
-
Kossoff, E.H.1
Laux, L.C.2
Blackford, R.3
Morrison, P.F.4
Pyzik, P.L.5
Hamdy, R.M.6
Turner, Z.7
Nordli, D.R.8
-
13
-
-
33748080476
-
Neuronal sensitivity to kainic acid is dependent on the Nrf2-mediated actions of the antioxidant response element
-
Kraft A.D., Lee J.M., Johnson D.A., Kan Y.W., Johnson J.A. Neuronal sensitivity to kainic acid is dependent on the Nrf2-mediated actions of the antioxidant response element. J. Neurochem. 2006, 98:1852-1865.
-
(2006)
J. Neurochem.
, vol.98
, pp. 1852-1865
-
-
Kraft, A.D.1
Lee, J.M.2
Johnson, D.A.3
Kan, Y.W.4
Johnson, J.A.5
-
14
-
-
1642282736
-
Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products
-
Levonen A.L., Landar A., Ramachandran A., Ceaser E.K., Dickinson D.A., Zanoni G., Morrow J.D., Darley-Usmar V.M. Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products. Biochem. J. 2004, 378:373-382.
-
(2004)
Biochem. J.
, vol.378
, pp. 373-382
-
-
Levonen, A.L.1
Landar, A.2
Ramachandran, A.3
Ceaser, E.K.4
Dickinson, D.A.5
Zanoni, G.6
Morrow, J.D.7
Darley-Usmar, V.M.8
-
15
-
-
30344473340
-
Seizure-induced changes in mitochondrial redox status
-
Liang L.P., Patel M. Seizure-induced changes in mitochondrial redox status. Free Radic. Biol. Med. 2006, 40:316-322.
-
(2006)
Free Radic. Biol. Med.
, vol.40
, pp. 316-322
-
-
Liang, L.P.1
Patel, M.2
-
16
-
-
0036139060
-
Breath acetone as a measure of systemic ketosis assessed in a rat model of the ketogenic diet
-
Likhodii S.S., Musa K., Cunnane S.C. Breath acetone as a measure of systemic ketosis assessed in a rat model of the ketogenic diet. Clin. Chem. 2002, 48:115-120.
-
(2002)
Clin. Chem.
, vol.48
, pp. 115-120
-
-
Likhodii, S.S.1
Musa, K.2
Cunnane, S.C.3
-
17
-
-
0033546686
-
Up-regulation of the human gamma-glutamylcysteine synthetase regulatory subunit gene involves binding of Nrf-2 to an electrophile responsive element
-
Moinova H.R., Mulcahy R.T. Up-regulation of the human gamma-glutamylcysteine synthetase regulatory subunit gene involves binding of Nrf-2 to an electrophile responsive element. Biochem. Biophys. Res. Commun. 1999, 261:661-668.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.261
, pp. 661-668
-
-
Moinova, H.R.1
Mulcahy, R.T.2
-
18
-
-
0037347447
-
Mitochondrial oxidation of 4-hydroxy-2-nonenal in rat cerebral cortex
-
Murphy T.C., Amarnath V., Picklo M.J. Mitochondrial oxidation of 4-hydroxy-2-nonenal in rat cerebral cortex. J. Neurochem. 2003, 84:1313-1321.
-
(2003)
J. Neurochem.
, vol.84
, pp. 1313-1321
-
-
Murphy, T.C.1
Amarnath, V.2
Picklo, M.J.3
-
19
-
-
49849100236
-
Growth of children on classical and medium-chain triglyceride ketogenic diets
-
Neal E.G., Chaffe H.M., Edwards N., Lawson M.S., Schwartz R.H., Cross J.H. Growth of children on classical and medium-chain triglyceride ketogenic diets. Pediatrics 2008, 122:e334-e340.
-
(2008)
Pediatrics
, vol.122
-
-
Neal, E.G.1
Chaffe, H.M.2
Edwards, N.3
Lawson, M.S.4
Schwartz, R.H.5
Cross, J.H.6
-
20
-
-
0041742490
-
Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress
-
Numazawa S., Ishikawa M., Yoshida A., Tanaka S., Yoshida T. Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress. Am. J. Physiol. Cell Physiol. 2003, 285:C334-C342.
-
(2003)
Am. J. Physiol. Cell Physiol.
, vol.285
-
-
Numazawa, S.1
Ishikawa, M.2
Yoshida, A.3
Tanaka, S.4
Yoshida, T.5
-
21
-
-
0032878018
-
Age-dependent differences in flurothyl seizure sensitivity in mice treated with a ketogenic diet
-
Rho J.M., Kim D.W., Robbins C.A., Anderson G.D., Schwartzkroin P.A. Age-dependent differences in flurothyl seizure sensitivity in mice treated with a ketogenic diet. Epilepsy Res. 1999, 37:233-240.
-
(1999)
Epilepsy Res.
, vol.37
, pp. 233-240
-
-
Rho, J.M.1
Kim, D.W.2
Robbins, C.A.3
Anderson, G.D.4
Schwartzkroin, P.A.5
-
22
-
-
0025948113
-
The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity
-
Rushmore T.H., Morton M.R., Pickett C.B. The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity. J. Biol. Chem. 1991, 266:11632-11639.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 11632-11639
-
-
Rushmore, T.H.1
Morton, M.R.2
Pickett, C.B.3
-
23
-
-
0031866530
-
Cellular mechanisms of resistance to chronic oxidative stress
-
Sagara Y., Dargusch R., Chambers D., Davis J., Schubert D., Maher P. Cellular mechanisms of resistance to chronic oxidative stress. Free Radic. Biol. Med. 1998, 24:1375-1389.
-
(1998)
Free Radic. Biol. Med.
, vol.24
, pp. 1375-1389
-
-
Sagara, Y.1
Dargusch, R.2
Chambers, D.3
Davis, J.4
Schubert, D.5
Maher, P.6
-
24
-
-
31444447800
-
Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers
-
Satoh T., Okamoto S.I., Cui J., Watanabe Y., Furuta K., Suzuki M., Tohyama K., Lipton S.A. Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers. Proc. Natl Acad. Sci. USA 2006, 103:768-773.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 768-773
-
-
Satoh, T.1
Okamoto, S.I.2
Cui, J.3
Watanabe, Y.4
Furuta, K.5
Suzuki, M.6
Tohyama, K.7
Lipton, S.A.8
-
26
-
-
0028075841
-
Quinone-induced oxidative stress elevates glutathione and induces gamma-glutamylcysteine synthetase activity in rat lung epithelial L2 cells
-
Shi M.M., Kugelman A., Iwamoto T., Tian L., Forman H.J. Quinone-induced oxidative stress elevates glutathione and induces gamma-glutamylcysteine synthetase activity in rat lung epithelial L2 cells. J. Biol. Chem. 1994, 269:26512-26517.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26512-26517
-
-
Shi, M.M.1
Kugelman, A.2
Iwamoto, T.3
Tian, L.4
Forman, H.J.5
-
27
-
-
27744438478
-
A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo
-
Shih A.Y., Li P., Murphy T.H. A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo. J. Neurosci. 2005, 25:10321-10335.
-
(2005)
J. Neurosci.
, vol.25
, pp. 10321-10335
-
-
Shih, A.Y.1
Li, P.2
Murphy, T.H.3
-
28
-
-
20744440945
-
Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo
-
Shih A.Y., Imbeault S., Barakauskas V., Erb H., Jiang L., Li P., Murphy T.H. Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo. J. Biol. Chem. 2005, 280:22925-22936.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 22925-22936
-
-
Shih, A.Y.1
Imbeault, S.2
Barakauskas, V.3
Erb, H.4
Jiang, L.5
Li, P.6
Murphy, T.H.7
-
29
-
-
0037996661
-
Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress
-
Shih A.Y., Johnson D.A., Wong G., Kraft A.D., Jiang L., Erb H., Johnson J.A., Murphy T.H. Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. J. Neurosci. 2003, 23:3394-3406.
-
(2003)
J. Neurosci.
, vol.23
, pp. 3394-3406
-
-
Shih, A.Y.1
Johnson, D.A.2
Wong, G.3
Kraft, A.D.4
Jiang, L.5
Erb, H.6
Johnson, J.A.7
Murphy, T.H.8
-
30
-
-
1642289587
-
The ketogenic diet increases mitochondrial uncoupling protein levels and activity
-
Sullivan P.G., Rippy N.A., Dorenbos K., Concepcion R.C., Agarwal A.K., Rho J.M. The ketogenic diet increases mitochondrial uncoupling protein levels and activity. Ann. Neurol. 2004, 55:576-580.
-
(2004)
Ann. Neurol.
, vol.55
, pp. 576-580
-
-
Sullivan, P.G.1
Rippy, N.A.2
Dorenbos, K.3
Concepcion, R.C.4
Agarwal, A.K.5
Rho, J.M.6
-
31
-
-
33748897867
-
Leptin contributes to slower weight gain in juvenile rodents on a ketogenic diet
-
Thio L.L., Erbayat-Altay E., Rensing N., Yamada K.A. Leptin contributes to slower weight gain in juvenile rodents on a ketogenic diet. Pediatr. Res. 2006, 60:413-417.
-
(2006)
Pediatr. Res.
, vol.60
, pp. 413-417
-
-
Thio, L.L.1
Erbayat-Altay, E.2
Rensing, N.3
Yamada, K.A.4
-
32
-
-
0031172884
-
Increased transcription of the regulatory subunit of gamma-glutamylcysteine synthetase in rat lung epithelial L2 cells exposed to oxidative stress or glutathione depletion
-
Tian L., Shi M.M., Forman H.J. Increased transcription of the regulatory subunit of gamma-glutamylcysteine synthetase in rat lung epithelial L2 cells exposed to oxidative stress or glutathione depletion. Arch. Biochem. Biophys. 1997, 342:126-133.
-
(1997)
Arch. Biochem. Biophys.
, vol.342
, pp. 126-133
-
-
Tian, L.1
Shi, M.M.2
Forman, H.J.3
-
33
-
-
0015295507
-
Anticonvulsant properties of the ketogenic diet in mice
-
Uhlemann E.R., Neims A.H. Anticonvulsant properties of the ketogenic diet in mice. J. Pharmacol. Exp. Ther. 1972, 180:231-238.
-
(1972)
J. Pharmacol. Exp. Ther.
, vol.180
, pp. 231-238
-
-
Uhlemann, E.R.1
Neims, A.H.2
-
34
-
-
0032541173
-
Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes
-
Vanden Hoek T.L., Becker L.B., Shao Z., Li C., Schumacker P.T. Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes. J. Biol. Chem. 1998, 273:18092-18098.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 18092-18098
-
-
Vanden Hoek, T.L.1
Becker, L.B.2
Shao, Z.3
Li, C.4
Schumacker, P.T.5
-
35
-
-
0029906134
-
Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene
-
Venugopal R., Jaiswal A.K. Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene. Proc. Natl Acad. Sci. USA 1996, 93:14960-14965.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 14960-14965
-
-
Venugopal, R.1
Jaiswal, A.K.2
-
36
-
-
0033584867
-
Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2
-
Wild A.C., Moinova H.R., Mulcahy R.T. Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2. J. Biol. Chem. 1999, 274:33627-33636.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33627-33636
-
-
Wild, A.C.1
Moinova, H.R.2
Mulcahy, R.T.3
-
38
-
-
0033231055
-
The role of glutathione in chronic adaptation to oxidative stress: studies in a normal rat kidney epithelial (NRK52E) cell model of sustained upregulation of glutathione biosynthesis
-
Woods J.S., Kavanagh T.J., Corral J., Reese A.W., Diaz D., Ellis M.E. The role of glutathione in chronic adaptation to oxidative stress: studies in a normal rat kidney epithelial (NRK52E) cell model of sustained upregulation of glutathione biosynthesis. Toxicol. Appl. Pharmacol. 1999, 160:207-216.
-
(1999)
Toxicol. Appl. Pharmacol.
, vol.160
, pp. 207-216
-
-
Woods, J.S.1
Kavanagh, T.J.2
Corral, J.3
Reese, A.W.4
Diaz, D.5
Ellis, M.E.6
-
39
-
-
29244479186
-
Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents
-
Zhao J., Kobori N., Aronowski J., Dash P.K. Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents. Neurosci. Lett. 2006, 393:108-112.
-
(2006)
Neurosci. Lett.
, vol.393
, pp. 108-112
-
-
Zhao, J.1
Kobori, N.2
Aronowski, J.3
Dash, P.K.4
-
40
-
-
34548850603
-
Enhancing expression of Nrf2-driven genes protects the blood brain barrier after brain injury
-
Zhao J., Moore A.N., Redell J.B., Dash P.K. Enhancing expression of Nrf2-driven genes protects the blood brain barrier after brain injury. J. Neurosci. 2007, 27:10240-10248.
-
(2007)
J. Neurosci.
, vol.27
, pp. 10240-10248
-
-
Zhao, J.1
Moore, A.N.2
Redell, J.B.3
Dash, P.K.4
|