-
1
-
-
0033835996
-
Peripherally administered antibodies against amyloid-β peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
Bard F.et al. Peripherally administered antibodies against amyloid-β peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat. Med. 6:2000;916-919.
-
(2000)
Nat. Med.
, vol.6
, pp. 916-919
-
-
Bard, F.1
-
2
-
-
0035203662
-
Key Factors in Alzheimer's disease: Β-amyloid precursor protein processing, metablosim and intraneuronal transport
-
Bayer T.A.et al. Key Factors in Alzheimer's disease: β-amyloid precursor protein processing, metablosim and intraneuronal transport. Brain Pathol. 11:2000;1-11.
-
(2000)
Brain Pathol.
, vol.11
, pp. 1-11
-
-
Bayer, T.A.1
-
3
-
-
0033943119
-
Transgenic mouse models of Alzheimer's disease
-
Borneman K.D., Staufenbiel M. Transgenic mouse models of Alzheimer's disease. Ann. N.Y. Acad. Sci. 908:2000;260-266.
-
(2000)
Ann. N.Y. Acad. Sci.
, vol.908
, pp. 260-266
-
-
Borneman, K.D.1
Staufenbiel, M.2
-
5
-
-
0035112647
-
BACE1 is the major beta-secretase for generation of Abeta peptides by neurons
-
Cai H., Wang Y., McCarthy D., Wen H., Borchelt D.R., Price D.L.et al. BACE1 is the major beta-secretase for generation of Abeta peptides by neurons. Nat. Neurosci. 4:2001;233-234.
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 233-234
-
-
Cai, H.1
Wang, Y.2
McCarthy, D.3
Wen, H.4
Borchelt, D.R.5
Price, D.L.6
-
6
-
-
0033849965
-
Studies on the in vitro assembly of a beta 1-40: Implications for the search for a beta fibril formation inhibitors
-
Goldsbury C.S.et al. Studies on the in vitro assembly of a beta 1-40: implications for the search for a beta fibril formation inhibitors. J. Struct. Biol. 130:2000;217-231.
-
(2000)
J. Struct. Biol.
, vol.130
, pp. 217-231
-
-
Goldsbury, C.S.1
-
7
-
-
0034718206
-
Approaches to discovery and characterization of inhibitors of amyloid-peptide polymerization
-
Findeis M.A.et al. Approaches to discovery and characterization of inhibitors of amyloid-peptide polymerization. Biochem. Biophys. Acta. 1502:2000;76-84.
-
(2000)
Biochem. Biophys. Acta
, vol.1502
, pp. 76-84
-
-
Findeis, M.A.1
-
8
-
-
0034700471
-
Aβ peptide immunization reduces behavioral impairment and plaques in a model of Alzheimer's disease
-
Janus C.et al. Aβ peptide immunization reduces behavioral impairment and plaques in a model of Alzheimer's disease. Nature. 408:2000;979-982.
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
-
9
-
-
0033857342
-
X-34, a fluorescent derivative of Congo red: A novel stochemical stain for Alzheimer's disease pathology
-
Styren S.D., Hamilton R.L., Styren G.C., Klunk W.W. X-34, a fluorescent derivative of Congo red: a novel histochemical stain for Alzheimer's disease pathology. J. Histo. Cytochem. 48:2000;1223-1232.
-
(2000)
J. Histo. Cytochem.
, vol.48
, pp. 1223-1232
-
-
Styren, S.D.1
Hamilton, R.L.2
Styren, G.C.3
Klunk, W.W.4
-
11
-
-
0011933729
-
Novel beta amyloid probes
-
Fillit HM, O'Connell AW, editors. Berlin: Springer
-
Kung M-P, et al. Novel beta amyloid probes. In: Fillit HM, O'Connell AW, editors. Drug Discovery and Development for Alzheimer's Disease. Berlin: Springer; 2000, p. 50-6.
-
(2000)
Drug Discovery and Development for Alzheimer's Disease
, pp. 50-56
-
-
Kung, M.-P.1
-
12
-
-
0033616682
-
Evolution of amyloid: What normal protein folding may tell us about fibrillogenesis and disease
-
Lansbury P.T. Evolution of amyloid: what normal protein folding may tell us about fibrillogenesis and disease. Proc. Natl. Acad. Sci. U.S.A. 96:1999;3342-3344.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 3342-3344
-
-
Lansbury, P.T.1
-
13
-
-
0037022828
-
Glu11 Site cleavage and N-terminally truncated Aβ production upon BACE overexpression
-
Liu K., Doms R.W., Lee V.M.-Y. Glu11 Site cleavage and N-terminally truncated Aβ production upon BACE overexpression. Biochemistry. 41:2002;3128-3136.
-
(2002)
Biochemistry
, vol.41
, pp. 3128-3136
-
-
Liu, K.1
Doms, R.W.2
Lee, V.M.-Y.3
-
14
-
-
0028172886
-
Veta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red
-
Lorenzo A., Yankner B.A. Veta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red. Proc. Natl. Acad. Sci. U.S.A. 91:1994;12243-12247.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 12243-12247
-
-
Lorenzo, A.1
Yankner, B.A.2
-
15
-
-
18744435477
-
Presenilin-1 mutations in Alzheimer's disease
-
Russo C.et al. Presenilin-1 mutations in Alzheimer's disease. Nature. 405:2001;531-532.
-
(2001)
Nature
, vol.405
, pp. 531-532
-
-
Russo, C.1
-
16
-
-
0033536163
-
Immunization with amyloid-β attenuates Alzheimer disease-like pathology in the PDAPP mouse
-
Schenk D. Immunization with amyloid-β attenuates Alzheimer disease-like pathology in the PDAPP mouse. Nature. 400:1999;173-177.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
-
17
-
-
0002680504
-
Biology of β-amyloid precursor protein and the mechanism of Alzheimer's disease
-
Terry, RD, Katzman, R, Bick, KL, Sisodia, SS, editors. Philadelphia, PA: Lippincot Williams & Wilkins
-
D.J. Selkoe, Biology of β-amyloid precursor protein and the mechanism of Alzheimer's disease. In: Terry, RD, Katzman, R, Bick, KL, Sisodia, SS, editors. Alzheimer's Disease. Philadelphia, PA: Lippincot Williams & Wilkins; 1999, p. 293-310.
-
(1999)
Alzheimer's Disease
, pp. 293-310
-
-
Selkoe, D.J.1
-
18
-
-
0034192158
-
β-Secretase revealed: Starting gate for race to novel Alzheimer therapies
-
Skovronsky D.M., Lee V.M.-Y. β-Secretase revealed: starting gate for race to novel Alzheimer therapies. Trends Pharmacol. Sci. 21:2000;161-163.
-
(2000)
Trends Pharmacol. Sci.
, vol.21
, pp. 161-163
-
-
Skovronsky, D.M.1
Lee, V.M.-Y.2
-
19
-
-
0034691124
-
In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease
-
Skovronsky D.M. In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 977:2000;609-7614.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.977
, pp. 609-7614
-
-
Skovronsky, D.M.1
-
20
-
-
0031873102
-
β-Sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: Implication for Alzheimer's therapy
-
Soto C., Sigurdsson E.M., Morelli L., Kumar A., Castano E.M., Frangione B. β-Sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implication for Alzheimer's therapy. Nat. Med. 4:1998;822-826.
-
(1998)
Nat. Med.
, vol.4
, pp. 822-826
-
-
Soto, C.1
Sigurdsson, E.M.2
Morelli, L.3
Kumar, A.4
Castano, E.M.5
Frangione, B.6
-
21
-
-
85043730362
-
Brain degeneration linked to "fatal attractions" of proteins in Alzheimer's disease and related disorders
-
in press
-
J.Q. Trojanowski, V.M.-Y. Lee. Brain degeneration linked to "fatal attractions" of proteins in Alzheimer's disease and related disorders. J. Alzheimer's Dis., in press.
-
J. Alzheimer's Dis.
-
-
Trojanowski, J.Q.1
Lee, V.M.-Y.2
-
22
-
-
0033595706
-
β-Secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar R.et al. β-Secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science. 286:1999;735-741.
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
-
23
-
-
0032800818
-
Intracellular APP processing and Aβ production in Alzheimer disease
-
Wilson C.A.et al. Intracellular APP processing and Aβ production in Alzheimer disease. J. Neuropath. Exper. Neurol. 58:1999;787-794.
-
(1999)
J. Neuropath. Exper. Neurol.
, vol.58
, pp. 787-794
-
-
Wilson, C.A.1
-
24
-
-
0033535553
-
Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity
-
Wolfe M.S.et al. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Nature. 398:1999;513-517.
-
(1999)
Nature
, vol.398
, pp. 513-517
-
-
Wolfe, M.S.1
-
25
-
-
0035821603
-
Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates
-
Zhuang Z.P.et al. Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates. J. Med. Chem. 44:2001;1905-1914.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 1905-1914
-
-
Zhuang, Z.P.1
|