-
1
-
-
0025761863
-
Effect of the glucocorticoid receptor antagonist RU38486 on muscle protein degradation in sepsis
-
Hall-Angerås, M., Angerås, U., Zamir, O., Hasselgren, P. O., and Fischer, J. E. (1991) Effect of the glucocorticoid receptor antagonist RU38486 on muscle protein degradation in sepsis. Surgery 109, 468-473
-
(1991)
Surgery
, vol.109
, pp. 468-473
-
-
Hall-Angerås, M.1
Angerås, U.2
Zamir, O.3
Hasselgren, P.O.4
Fischer, J.E.5
-
2
-
-
0022587698
-
Blockade of glucocorticoid receptor binding and inhibition of dexamethasone-induced muscle atrophy in rat by RU38486, a potent glucocorticoid antagonist
-
Konagaya, M., Bernard, P. A., and Max, S. R. (1986) Blockade of glucocorticoid receptor binding and inhibition of dexamethasone-induced muscle atrophy in rat by RU38486, a potent glucocorticoid antagonist. Endocrinology 119, 375-380
-
(1986)
Endocrinology
, vol.119
, pp. 375-380
-
-
Konagaya, M.1
Bernard, P.A.2
Max, S.R.3
-
3
-
-
0027972943
-
Acidosis and glucocorticoids concomitantly increase ubiquitin and proteasome subunit mRNA levels in rat muscle
-
Price, S. R., England, B. K., Bailey, J. L., Van Vreede, K., and Mitch, W. E. (1994) Acidosis and glucocorticoids concomitantly increase ubiquitin and proteasome subunit mRNA levels in rat muscle. Am. J. Physiol. Cell Physiol. 267, C955-C960
-
(1994)
Am. J. Physiol. Cell Physiol.
, vol.267
-
-
Price, S.R.1
England, B.K.2
Bailey, J.L.3
Van Vreede, K.4
Mitch, W.E.5
-
4
-
-
1542284640
-
Glucocorticoids regulate mRNA levels for subunits of the 19 S regulatory complex of the 26 S proteasome in fast-twitch skeletal muscles
-
Combaret, L., Taillandier, D., Dardevet, D., Bechet, D., Ralliere, C., Claustre, A., Grizard, J., and Attaix, D. (2004) Glucocorticoids regulate mRNA levels for subunits of the 19 S regulatory complex of the 26 S proteasome in fast-twitch skeletal muscles. Biochem. J. 378, 239-246
-
(2004)
Biochem. J.
, vol.378
, pp. 239-246
-
-
Combaret, L.1
Taillandier, D.2
Dardevet, D.3
Bechet, D.4
Ralliere, C.5
Claustre, A.6
Grizard, J.7
Attaix, D.8
-
5
-
-
0030909411
-
Activation of the ubiquitin pathway in rat skeletal muscle by catabolic doses of glucocorticoids
-
Auclair, D., Garrel, D. R., Zerouala, A. C., and Ferland, L. H. (1997) Activation of the ubiquitin pathway in rat skeletal muscle by catabolic doses of glucocorticoids. Am. J. Physiol. Cell Physiol. 272, C1007-C1016
-
(1997)
Am. J. Physiol. Cell Physiol.
, vol.272
-
-
Auclair, D.1
Garrel, D.R.2
Zerouala, A.C.3
Ferland, L.H.4
-
6
-
-
0033305506
-
Regulation of components of the ubiquitin system by insulin-like growth factor I and growth hormone in skeletal muscle of rats made catabolic with dexamethasone
-
Chrysis, D., and Underwood, L. E. (1999) Regulation of components of the ubiquitin system by insulin-like growth factor I and growth hormone in skeletal muscle of rats made catabolic with dexamethasone. Endocrinology 140, 5635-5641
-
(1999)
Endocrinology
, vol.140
, pp. 5635-5641
-
-
Chrysis, D.1
Underwood, L.E.2
-
7
-
-
11144356337
-
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
-
Sandri, M., Sandri, C., Gilbert, A., Skurk, C., Calabria, E., Picard, A., Walsh, K., Schiaffino, S., Lecker, S. H., and Goldberg, A. L. (2004) Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 117, 399-412
-
(2004)
Cell
, vol.117
, pp. 399-412
-
-
Sandri, M.1
Sandri, C.2
Gilbert, A.3
Skurk, C.4
Calabria, E.5
Picard, A.6
Walsh, K.7
Schiaffino, S.8
Lecker, S.H.9
Goldberg, A.L.10
-
8
-
-
0034733634
-
Glucocorticoids induce proteasome C3 subunit expression in L6 muscle cells by opposing the suppression of its transcription by NF-κB
-
Du, J., Mitch, W. E., Wang, X., and Price, S. R. (2000) Glucocorticoids induce proteasome C3 subunit expression in L6 muscle cells by opposing the suppression of its transcription by NF-κB. J. Biol. Chem. 275, 19661-19666
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 19661-19666
-
-
Du, J.1
Mitch, W.E.2
Wang, X.3
Price, S.R.4
-
9
-
-
0037053304
-
Ubiquitin (UbC) expression in muscle cells is increased by glucocorticoids through a mechanism involving Sp1 and MEK1
-
Marinovic, A. C., Zheng, B., Mitch, W. E., and Price, S. R. (2002) Ubiquitin (UbC) expression in muscle cells is increased by glucocorticoids through a mechanism involving Sp1 and MEK1. J. Biol. Chem. 277, 16673-16681
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 16673-16681
-
-
Marinovic, A.C.1
Zheng, B.2
Mitch, W.E.3
Price, S.R.4
-
10
-
-
2042425906
-
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
-
Stitt, T. N., Drujan, D., Clarke, B. A., Panaro, F., Timofeyva, Y., Kline, W. O., Gonzalez, M., Yancopoulos, G. D., and Glass, D. J. (2004) The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol. Cell 14, 395-403
-
(2004)
Mol. Cell
, vol.14
, pp. 395-403
-
-
Stitt, T.N.1
Drujan, D.2
Clarke, B.A.3
Panaro, F.4
Timofeyva, Y.5
Kline, W.O.6
Gonzalez, M.7
Yancopoulos, G.D.8
Glass, D.J.9
-
11
-
-
5444262078
-
IKKbeta/NF-kappaB activation causes severe muscle wasting in mice
-
Cai, D., Frantz, J. D., Tawa, N. E., Jr., Melendez, P. A., Oh, B. C., Lidov, H. G., Hasselgren, P. O., Frontera, W. R., Lee, J., Glass, D. J., and Shoelson, S. E. (2004) IKKbeta/NF-kappaB activation causes severe muscle wasting in mice. Cell 119, 285-298
-
(2004)
Cell
, vol.119
, pp. 285-298
-
-
Cai, D.1
Frantz, J.D.2
Tawa Jr., N.E.3
Melendez, P.A.4
Oh, B.C.5
Lidov, H.G.6
Hasselgren, P.O.7
Frontera, W.R.8
Lee, J.9
Glass, D.J.10
Shoelson, S.E.11
-
12
-
-
33846855369
-
Tissue-specific regulation of ubiquitin (UbC) transcription by glucocorticoids: In vivo and in vitro analyses
-
Marinovic, A. C., Zheng, B., Mitch, W. E., and Price, S. R. (2007) Tissue-specific regulation of ubiquitin (UbC) transcription by glucocorticoids: In vivo and in vitro analyses. Am. J. Physiol. Renal Physiol. 292, F660-F666
-
(2007)
Am. J. Physiol. Renal Physiol.
, vol.292
-
-
Marinovic, A.C.1
Zheng, B.2
Mitch, W.E.3
Price, S.R.4
-
13
-
-
70349658713
-
Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice
-
Hu, Z., Wang, H., Lee, I. H., Du, J., and Mitch, W. E. (2009) Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice. J. Clin. Invest. 119, 3059-3069
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3059-3069
-
-
Hu, Z.1
Wang, H.2
Lee, I.H.3
Du, J.4
Mitch, W.E.5
-
14
-
-
0036081477
-
Expression and binding activity of the glucocorticoid receptor are upregulated in septic muscle
-
Sun, X., Fischer, D. R., Pritts, T. A., Wray, C. J., and Hasselgren, P. O. (2002) Expression and binding activity of the glucocorticoid receptor are upregulated in septic muscle. Am. J. Physiol. 282, R509-R518
-
(2002)
Am. J. Physiol.
, vol.282
-
-
Sun, X.1
Fischer, D.R.2
Pritts, T.A.3
Wray, C.J.4
Hasselgren, P.O.5
-
15
-
-
0027163954
-
Glucocorticoid regulation of insulin receptor and substrate IRS-1 tyrosine phosphorylation in rat skeletal muscle in vivo
-
Giorgino, F., Almahfouz, A., Goodyear, L. J., and Smith, R. J. (1993) Glucocorticoid regulation of insulin receptor and substrate IRS-1 tyrosine phosphorylation in rat skeletal muscle in vivo. J. Clin. Invest. 91, 2020-2030
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 2020-2030
-
-
Giorgino, F.1
Almahfouz, A.2
Goodyear, L.J.3
Smith, R.J.4
-
16
-
-
0027489828
-
Modulation of insulin receptor, insulin receptor substrate-1 and phoshatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats
-
Saad, M. J. A., Folli, F., Kahn, J. A., and Kahn, C. R. (1993) Modulation of insulin receptor, insulin receptor substrate-1 and phoshatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats. J. Clin. Invest. 92, 2065-2072
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 2065-2072
-
-
Saad, M.J.A.1
Folli, F.2
Kahn, J.A.3
Kahn, C.R.4
-
17
-
-
0030614873
-
Specific increase in p85α expression in response to dexamethasone is associated with inhibition of insulin-like growth factor-I stimulated phosphatidylinositol 3-kinase activity in cultured muscle cells
-
Giorgino, F., Pedrini, M. T., Matera, L., and Smith, R. J. (1997) Specific increase in p85α expression in response to dexamethasone is associated with inhibition of insulin-like growth factor-I stimulated phosphatidylinositol 3-kinase activity in cultured muscle cells. J. Biol. Chem. 272, 7455-7463
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7455-7463
-
-
Giorgino, F.1
Pedrini, M.T.2
Matera, L.3
Smith, R.J.4
-
18
-
-
0033060435
-
Evaluation of signals activating ubiquitin-proteasome proteolysis in a model of muscle wasting
-
Mitch, W. E., Bailey, J. L., Wang, X., Jurkovitz, C., Newby, D., and Price, S. R. (1999) Evaluation of signals activating ubiquitin-proteasome proteolysis in a model of muscle wasting. Am. J. Physiol. Cell Physiol. 276, C1132-C1138
-
(1999)
Am. J. Physiol. Cell Physiol.
, vol.276
-
-
Mitch, W.E.1
Bailey, J.L.2
Wang, X.3
Jurkovitz, C.4
Newby, D.5
Price, S.R.6
-
19
-
-
0029861468
-
Muscle wasting in insulinopenic rats results from activation of the ATP-dependent, ubiquitin proteasome proteolytic pathway by a mechanism including gene transcription
-
Price, S. R., Bailey, J. L., Wang, X., Jurkovitz, C., England, B. K., Ding, X., Phillips, L. S., and Mitch, W. E. (1996) Muscle wasting in insulinopenic rats results from activation of the ATP-dependent, ubiquitin proteasome proteolytic pathway by a mechanism including gene transcription. J. Clin. Invest. 98, 1703-1708
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1703-1708
-
-
Price, S.R.1
Bailey, J.L.2
Wang, X.3
Jurkovitz, C.4
England, B.K.5
Ding, X.6
Phillips, L.S.7
Mitch, W.E.8
-
20
-
-
4644253582
-
Acidosis impairs insulin receptor substrate-1-associated phosphoinositide 3-kinase signaling in muscle cells: Consequences on proteolysis
-
Franch, H. A., Raissi, S., Wang, X., Zheng, B., Bailey, J. L., and Price, S. R. (2004) Acidosis impairs insulin receptor substrate-1-associated phosphoinositide 3-kinase signaling in muscle cells: consequences on proteolysis. Am. J. Physiol. Renal Physiol. 287, F700-F706
-
(2004)
Am. J. Physiol. Renal Physiol.
, vol.287
-
-
Franch, H.A.1
Raissi, S.2
Wang, X.3
Zheng, B.4
Bailey, J.L.5
Price, S.R.6
-
21
-
-
57349154378
-
Regulation of caspase-3 activity by insulin in skeletal muscle cells involves PI3-kinase and MEK1/2
-
Gao, Y., Ordas, R., Klein, J. D., and Price, S. R. (2008) Regulation of caspase-3 activity by insulin in skeletal muscle cells involves PI3-kinase and MEK1/2. J. Appl. Physiol. 105, 1772-1778
-
(2008)
J. Appl. Physiol.
, vol.105
, pp. 1772-1778
-
-
Gao, Y.1
Ordas, R.2
Klein, J.D.3
Price, S.R.4
-
22
-
-
0033793393
-
Pitfall of an internal control plasmid: Response of Renilla luciferase (pRL-TK) plasmid to dihydrotestosterone and dexamethasone
-
Ibrahim, N. M., Marinovic, A. C., Price, S. R., Young, L. G., and Frohlich, O. (2000) Pitfall of an internal control plasmid: response of Renilla luciferase (pRL-TK) plasmid to dihydrotestosterone and dexamethasone. BioTechniques 29, 782-784
-
(2000)
BioTechniques
, vol.29
, pp. 782-784
-
-
Ibrahim, N.M.1
Marinovic, A.C.2
Price, S.R.3
Young, L.G.4
Frohlich, O.5
-
23
-
-
0034596261
-
Tools for evaluating ubiquitin (UbC) gene expression: Characterization of the rat UbC promoter and use of an unique 3′ mRNA sequence
-
Marinovic, A. C., Mitch, W. E., and Price, S. R. (2000) Tools for evaluating ubiquitin (UbC) gene expression: characterization of the rat UbC promoter and use of an unique 3′ mRNA sequence. Biochem. Biophys. Res. Commun. 274, 537-541
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.274
, pp. 537-541
-
-
Marinovic, A.C.1
Mitch, W.E.2
Price, S.R.3
-
24
-
-
0028277967
-
Nucleotide sequence and expression of the rat polyubiquitin mRNA
-
Hayashi, T., Noga, M., and Matsuda, M. (1994) Nucleotide sequence and expression of the rat polyubiquitin mRNA. Biochim. Biophys. Acta 1218, 232-234
-
(1994)
Biochim. Biophys. Acta
, vol.1218
, pp. 232-234
-
-
Hayashi, T.1
Noga, M.2
Matsuda, M.3
-
25
-
-
4544293878
-
IGF-1 stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin-ligases, atrogin-1 and MuRF1
-
Sacheck, J. M., Ohtsuka, A., McLary, S. C., and Goldberg, A. L. (2004) IGF-1 stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin-ligases, atrogin-1 and MuRF1. Am. J. Physiol. Endocrinol. Metab. 287, E591-E601
-
(2004)
Am. J. Physiol. Endocrinol. Metab.
, vol.287
-
-
Sacheck, J.M.1
Ohtsuka, A.2
McLary, S.C.3
Goldberg, A.L.4
-
26
-
-
3242679772
-
The COX-2 pathway is essential during early stages of skeletal muscle regeneration
-
Bondesen, B. A., Mills, S. T., Kegley, K. M., and Pavlath, G. K. (2004) The COX-2 pathway is essential during early stages of skeletal muscle regeneration. Am. J. Physiol. Cell Physiol. 287, C475-C483
-
(2004)
Am. J. Physiol. Cell Physiol.
, vol.287
-
-
Bondesen, B.A.1
Mills, S.T.2
Kegley, K.M.3
Pavlath, G.K.4
-
27
-
-
21444460644
-
Differential contribution of insulin receptor substrates 1 versus 2 to insulin signaling and glucose uptake in L6 myotubes
-
Huang, C., Thirone, A. C., Huang, X., and Klip, A. (2005) Differential contribution of insulin receptor substrates 1 versus 2 to insulin signaling and glucose uptake in L6 myotubes. J. Biol. Chem. 280, 19426-19435
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 19426-19435
-
-
Huang, C.1
Thirone, A.C.2
Huang, X.3
Klip, A.4
-
28
-
-
0026539998
-
Insulin stimulation of phosphatidylinositol 3-kinase activity and association with insulin receptor substrate 1 in liver and muscle of the intact rat
-
Folli, F., Saad, M. J. A., Backer, J. M., and Kahn, C. R. (1992) Insulin stimulation of phosphatidylinositol 3-kinase activity and association with insulin receptor substrate 1 in liver and muscle of the intact rat. J. Biol. Chem. 267, 22171-22177
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 22171-22177
-
-
Folli, F.1
Saad, M.J.A.2
Backer, J.M.3
Kahn, C.R.4
-
29
-
-
0026788330
-
Influence of ammonia and pH on protein and amino acid metabolism in LLC-PK1 cells
-
Jurkovitz, C. T., England, B. K., Ebb, R. G., and Mitch, W. E. (1992) Influence of ammonia and pH on protein and amino acid metabolism in LLC-PK1 cells. Kidney Int. 42, 595-601
-
(1992)
Kidney Int.
, vol.42
, pp. 595-601
-
-
Jurkovitz, C.T.1
England, B.K.2
Ebb, R.G.3
Mitch, W.E.4
-
31
-
-
0024370493
-
Regulation of protein synthesis and degradation in L8 myotubes: Effects of serum, insulin, and insulin-like growth factors
-
Gulve, E. A., and Dice, J. F. (1989) Regulation of protein synthesis and degradation in L8 myotubes: effects of serum, insulin, and insulin-like growth factors. Biochem. J. 260, 377-387
-
(1989)
Biochem. J.
, vol.260
, pp. 377-387
-
-
Gulve, E.A.1
Dice, J.F.2
-
32
-
-
85047693596
-
Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions
-
Du, J., Wang, X., Miereles, C., Bailey, J. L., Debigare, R., Zheng, B., Price, S. R., and Mitch, W. E. (2004) Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions. J. Clin. Invest. 113, 115-123
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 115-123
-
-
Du, J.1
Wang, X.2
Miereles, C.3
Bailey, J.L.4
Debigare, R.5
Zheng, B.6
Price, S.R.7
Mitch, W.E.8
-
33
-
-
33750740115
-
Development of a diagnostic method for detecting increased muscle protein degradation in patients with catabolic conditions
-
Workeneh, B. T., Rondon-Berrios, H., Zhang, L., Hu, Z., Ayehu, G., Ferrando, A., Kopple, J. D., Wang, H., Storer, T., Fournier, M., Lee, S. W., Du, J., and Mitch, W. E. (2006) Development of a diagnostic method for detecting increased muscle protein degradation in patients with catabolic conditions. J. Am. Soc. Nephrol. 17, 3233-3239
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 3233-3239
-
-
Workeneh, B.T.1
Rondon-Berrios, H.2
Zhang, L.3
Hu, Z.4
Ayehu, G.5
Ferrando, A.6
Kopple, J.D.7
Wang, H.8
Storer, T.9
Fournier, M.10
Lee, S.W.11
Du, J.12
Mitch, W.E.13
-
34
-
-
36448968532
-
FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells
-
Zhao, J., Brault, J. J., Schild, A., Cao, P., Sandri, M., Schiaffino, S., Lecker, S. H., and Goldberg, A. L. (2007) FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab. 6, 472-483
-
(2007)
Cell Metab.
, vol.6
, pp. 472-483
-
-
Zhao, J.1
Brault, J.J.2
Schild, A.3
Cao, P.4
Sandri, M.5
Schiaffino, S.6
Lecker, S.H.7
Goldberg, A.L.8
-
35
-
-
33751533918
-
The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling
-
Guo, S., Dunn, S. L., and White, M. F. (2006) The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling. Mol. Endocrinol. 20, 3389-3399
-
(2006)
Mol. Endocrinol.
, vol.20
, pp. 3389-3399
-
-
Guo, S.1
Dunn, S.L.2
White, M.F.3
-
36
-
-
2342483040
-
SREBPs suppress IRS-2-mediated insulin signalling in the liver
-
Ide, T., Shimano, H., Yahagi, N., Matsuzaka, T., Nakakuki, M., Yamamoto, T., Nakagawa, Y., Takahashi, A., Suzuki, H., Sone, H., Toyoshima, H., Fukamizu, A., and Yamada, N. (2004) SREBPs suppress IRS-2-mediated insulin signalling in the liver. Nat. Cell Biol. 6, 351-357
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 351-357
-
-
Ide, T.1
Shimano, H.2
Yahagi, N.3
Matsuzaka, T.4
Nakakuki, M.5
Yamamoto, T.6
Nakagawa, Y.7
Takahashi, A.8
Suzuki, H.9
Sone, H.10
Toyoshima, H.11
Fukamizu, A.12
Yamada, N.13
-
37
-
-
0347285363
-
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
-
Lecker, S. H., Jagoe, R. T., Gilbert, A., Gomes, M., Baracos, V., Bailey, J., Price, S. R., Mitch, W. E., and Goldberg, A. L. (2004) Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J. 18, 39-51
-
(2004)
FASEB J.
, vol.18
, pp. 39-51
-
-
Lecker, S.H.1
Jagoe, R.T.2
Gilbert, A.3
Gomes, M.4
Baracos, V.5
Bailey, J.6
Price, S.R.7
Mitch, W.E.8
Goldberg, A.L.9
-
38
-
-
0028897653
-
Coordinated induction of the ubiquitin conjugation pathway accompanies the devolopmentally programmed death of insect skeletal muscle
-
Haas, A. L., Baboshina, O., Williams, B., and Schwartz, L. M. (1995) Coordinated induction of the ubiquitin conjugation pathway accompanies the devolopmentally programmed death of insect skeletal muscle. J. Biol. Chem. 270, 9407-9412
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 9407-9412
-
-
Haas, A.L.1
Baboshina, O.2
Williams, B.3
Schwartz, L.M.4
-
39
-
-
0023115331
-
The dynamics of ubiquitin pools within cultured human lung fibroblasts
-
Haas, A. L., and Bright, P. M. (1987) The dynamics of ubiquitin pools within cultured human lung fibroblasts. J. Biol. Chem. 262, 345-351
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 345-351
-
-
Haas, A.L.1
Bright, P.M.2
-
40
-
-
0344629427
-
Ubiquitin depletion as a key mediator of toxicity by translational inhibitors
-
Hanna, J., Leggett, D. S., and Finley, D. (2003) Ubiquitin depletion as a key mediator of toxicity by translational inhibitors. Mol. Cell. Biol. 23, 9251-9261
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 9251-9261
-
-
Hanna, J.1
Leggett, D.S.2
Finley, D.3
-
41
-
-
67749086824
-
Ubiquitin degradation with its substrate, or as a monomer in a ubiquitination-independent mode, provides clues to proteasome regulation
-
Shabek, N., Herman-Bachinsky, Y., and Ciechanover, A. (2009) Ubiquitin degradation with its substrate, or as a monomer in a ubiquitination-independent mode, provides clues to proteasome regulation. Proc. Natl. Acad. Sci. U. S. A. 106, 11907-11912
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 11907-11912
-
-
Shabek, N.1
Herman-Bachinsky, Y.2
Ciechanover, A.3
-
42
-
-
0030593939
-
Mechanisms of muscle wasting: The role of the ubiquitin-proteasome pathway
-
Mitch, W. E., and Goldberg, A. L. (1996) Mechanisms of muscle wasting: the role of the ubiquitin-proteasome pathway. N. Engl. J. Med. 335, 1897-1905
-
(1996)
N. Engl. J. Med.
, vol.335
, pp. 1897-1905
-
-
Mitch, W.E.1
Goldberg, A.L.2
-
43
-
-
56049123409
-
The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy associated with MuRF1 gene
-
Waddell, D. S., Baehr, L. M., van den Brandt, J., Johnsen, S. A., Reichardt, H. M., Furlow, J. D., and Bodine, S. C. (2008) The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy associated with MuRF1 gene. Am. J. Physiol. Endocrinol. Metab. 295, E785-E797
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.295
-
-
Waddell, D.S.1
Baehr, L.M.2
Van Den Brandt, J.3
Johnsen, S.A.4
Reichardt, H.M.5
Furlow, J.D.6
Bodine, S.C.7
-
44
-
-
0035941020
-
Identification of ubiquitin ligases required for skeletal muscle atrophy
-
Bodine, S. C., Latres, E., Baumhueter, S., Lai, V. K., Nunez, L., Clarke, B. A., Poueymirou, W. T., Panaro, F. J., Na, E., Dharmarajan, K., Pan, Z. Q., Valenzuela, D. M., DeChiara, T. M., Stitt, T. N., Yancopoulos, G. D., and Glass, D. J. (2001) Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 294, 1704-1708
-
(2001)
Science
, vol.294
, pp. 1704-1708
-
-
Bodine, S.C.1
Latres, E.2
Baumhueter, S.3
Lai, V.K.4
Nunez, L.5
Clarke, B.A.6
Poueymirou, W.T.7
Panaro, F.J.8
Na, E.9
Dharmarajan, K.10
Pan, Z.Q.11
Valenzuela, D.M.12
DeChiara, T.M.13
Stitt, T.N.14
Yancopoulos, G.D.15
Glass, D.J.16
-
45
-
-
0842312950
-
Glucocorticoid receptor counteracts tumorigenic activity of akt in skin through interference with the phosphatidylinositol 3-kinase signaling pathway
-
Leis, H., Page, A., Ramirez, A., Bravo, A., Segrelles, C., Paramio, J., Barettino, D., Jorcano, J. L., and Perez, P. (2004) Glucocorticoid receptor counteracts tumorigenic activity of akt in skin through interference with the phosphatidylinositol 3-kinase signaling pathway. Mol. Endocrinol. 18, 303-311
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 303-311
-
-
Leis, H.1
Page, A.2
Ramirez, A.3
Bravo, A.4
Segrelles, C.5
Paramio, J.6
Barettino, D.7
Jorcano, J.L.8
Perez, P.9
-
46
-
-
68849087517
-
Ubiquitin ligase Cbl-b is a negative regulator for IGF-1 signaling during muscle atrophy caused by unloading
-
Nakao, R., Hirasaka, K., Goto, J., Ishidoh, K., Yamada, C., Ohno, A., Okumura, Y., Nonaka, I., Yasutomo, K., Baldwin, K. M., Kominami, E., Higashibata, A., Nagano, K., Tanaka, K., Yasui, N., Mills, E. M., Takeda, S., and Nikawa, T. (2009) Ubiquitin ligase Cbl-b is a negative regulator for IGF-1 signaling during muscle atrophy caused by unloading. Mol. Cell. Biol. 29, 4798-4811
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 4798-4811
-
-
Nakao, R.1
Hirasaka, K.2
Goto, J.3
Ishidoh, K.4
Yamada, C.5
Ohno, A.6
Okumura, Y.7
Nonaka, I.8
Yasutomo, K.9
Baldwin, K.M.10
Kominami, E.11
Higashibata, A.12
Nagano, K.13
Tanaka, K.14
Yasui, N.15
Mills, E.M.16
Takeda, S.17
Nikawa, T.18
-
47
-
-
33644514920
-
Tissue-specific roles of IRS proteins in insulin signaling and glucose transport
-
Thirone, A. C., Huang, C., and Klip, A. (2006) Tissue-specific roles of IRS proteins in insulin signaling and glucose transport. Trends Endocrinol. Metab. 17, 72-78
-
(2006)
Trends Endocrinol. Metab.
, vol.17
, pp. 72-78
-
-
Thirone, A.C.1
Huang, C.2
Klip, A.3
-
48
-
-
20444376132
-
Transgenic and knockout mice in diabetes research: Novel insights into pathophysiology, limitations, and perspectives
-
Plum, L., Wunderlich, F. T., Baudler, S., Krone, W., and Bruning, J. C. (2005) Transgenic and knockout mice in diabetes research: novel insights into pathophysiology, limitations, and perspectives. Physiology 20, 152-161
-
(2005)
Physiology
, vol.20
, pp. 152-161
-
-
Plum, L.1
Wunderlich, F.T.2
Baudler, S.3
Krone, W.4
Bruning, J.C.5
-
49
-
-
0032836611
-
Calorie restriction increases insulin-stimulated glucose transport in skeletal muscle from IRS-1 knockout mice
-
Gazdag, A. C., Dumke, C. L., Kahn, C. R., and Cartee, G. D. (1999) Calorie restriction increases insulin-stimulated glucose transport in skeletal muscle from IRS-1 knockout mice. Diabetes 48, 1930-1936
-
(1999)
Diabetes
, vol.48
, pp. 1930-1936
-
-
Gazdag, A.C.1
Dumke, C.L.2
Kahn, C.R.3
Cartee, G.D.4
-
50
-
-
18544387465
-
Heterozygous knockout of the IRS-1 gene in mice enhances obesity-linked insulin resistance: A possible model for the development of type 2 diabetes
-
Shirakami, A., Toyonaga, T., Tsuruzoe, K., Shirotani, T., Matsumoto, K., Yoshizato, K., Kawashima, J., Hirashima, Y., Miyamura, N., Kahn, C. R., and Araki, E. (2002) Heterozygous knockout of the IRS-1 gene in mice enhances obesity-linked insulin resistance: a possible model for the development of type 2 diabetes. J. Endocrinol. 174, 309-319
-
(2002)
J. Endocrinol.
, vol.174
, pp. 309-319
-
-
Shirakami, A.1
Toyonaga, T.2
Tsuruzoe, K.3
Shirotani, T.4
Matsumoto, K.5
Yoshizato, K.6
Kawashima, J.7
Hirashima, Y.8
Miyamura, N.9
Kahn, C.R.10
Araki, E.11
-
51
-
-
33646354403
-
Chronic kidney disease causes defects in signaling through the insulin receptor substrate/phosphatidylinositol 3-kinase/Akt pathway: Implications for muscle atrophy
-
Bailey, J. L., Zheng, B., Hu, Z., Price, S. R., and Mitch, W. E. (2006) Chronic kidney disease causes defects in signaling through the insulin receptor substrate/phosphatidylinositol 3-kinase/Akt pathway: implications for muscle atrophy. J. Am. Soc. Nephrol. 17, 1388-1394
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 1388-1394
-
-
Bailey, J.L.1
Zheng, B.2
Hu, Z.3
Price, S.R.4
Mitch, W.E.5
-
52
-
-
41849128523
-
The FoxO code
-
Calnan, D. R., and Brunet, A. (2008) The FoxO code. Oncogene 27, 2276-2288
-
(2008)
Oncogene
, vol.27
, pp. 2276-2288
-
-
Calnan, D.R.1
Brunet, A.2
-
53
-
-
0024396320
-
Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins
-
Mitchell, P. J., and Tijan, R. (1988) Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 245, 371-378
-
(1988)
Science
, vol.245
, pp. 371-378
-
-
Mitchell, P.J.1
Tijan, R.2
-
54
-
-
23044439366
-
Transcriptional activity of Sp1 is regulated by molecular interactions between the zinc finger DNA binding domain and the inhibitory domain with corepressors, and this interaction is modulated by MEK
-
Lee, J. A., Suh, D. C., Kang, J. E., Kim, M. H., Park, H., Lee, M. N., Kim, J. M., Jeon, B. N., Roh, H. E., Yu, M. Y., Choi, K. Y., Kim, K. Y., and Hur, M. W. (2005) Transcriptional activity of Sp1 is regulated by molecular interactions between the zinc finger DNA binding domain and the inhibitory domain with corepressors, and this interaction is modulated by MEK. J. Biol. Chem. 280, 28061-28071
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 28061-28071
-
-
Lee, J.A.1
Suh, D.C.2
Kang, J.E.3
Kim, M.H.4
Park, H.5
Lee, M.N.6
Kim, J.M.7
Jeon, B.N.8
Roh, H.E.9
Yu, M.Y.10
Choi, K.Y.11
Kim, K.Y.12
Hur, M.W.13
-
55
-
-
0033052233
-
Neu differentiation factor stimulates phosphorylation and activation of the Sp1 transcription factor
-
Alroy, I., Soussan, L., Seger, R., and Yarden, Y. (1999) Neu differentiation factor stimulates phosphorylation and activation of the Sp1 transcription factor. Mol. Cell. Biol. 19, 1961-1972
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 1961-1972
-
-
Alroy, I.1
Soussan, L.2
Seger, R.3
Yarden, Y.4
-
56
-
-
0030973394
-
Casein kinase II-mediated phosphorylation of the C terminus of Sp1 decreases its DNA binding activity
-
Armstrong, S. A., Barry, D. A., Leggett, R. W., and Mueller, C. R. (1997) Casein kinase II-mediated phosphorylation of the C terminus of Sp1 decreases its DNA binding activity. J. Biol. Chem. 272, 13489-13495
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13489-13495
-
-
Armstrong, S.A.1
Barry, D.A.2
Leggett, R.W.3
Mueller, C.R.4
-
57
-
-
0024276524
-
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif
-
Courey, A. J., and Tjian, R. (1988) Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell 55, 887-898
-
(1988)
Cell
, vol.55
, pp. 887-898
-
-
Courey, A.J.1
Tjian, R.2
-
58
-
-
0035887030
-
Cyclin A-CDK phosphorylates Sp1 and enhances Sp1-mediated transcription
-
Fojas, d. B., Collins, N. K., Du, P., Azizkhan-Clifford, J., and Mudryj, M. (2001) Cyclin A-CDK phosphorylates Sp1 and enhances Sp1-mediated transcription. EMBO J. 20, 5737-5747
-
(2001)
EMBO J.
, vol.20
, pp. 5737-5747
-
-
Fojas, D.B.1
Collins, N.K.2
Du, P.3
Azizkhan-Clifford, J.4
Mudryj, M.5
-
59
-
-
0034737501
-
Protein phosphatase 2A and phosphatidylinositol 3-kinase regulate the activity of Sp1-responsive promoters
-
Garcia, A., Cereghini, S., and Sontag, E. (2000) Protein phosphatase 2A and phosphatidylinositol 3-kinase regulate the activity of Sp1-responsive promoters. J. Biol. Chem. 275, 9385-9389
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9385-9389
-
-
Garcia, A.1
Cereghini, S.2
Sontag, E.3
|