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Volumn 14, Issue 4, 2010, Pages

Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; FLAGELLIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; MACROPHAGE MIGRATION INHIBITION FACTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 5; TUMOR NECROSIS FACTOR ALPHA; CXCL2 CHEMOKINE; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; PARP1 PROTEIN, MOUSE; TLR6 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 6; TREM1 PROTEIN, MOUSE;

EID: 77955795087     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc9235     Document Type: Article
Times cited : (47)

References (36)
  • 3
    • 33846829490 scopus 로고    scopus 로고
    • How flagellin and toll-like receptor 5 contribute to enteric infection
    • 10.1128/IAI.01506-06, 1828527, 17118981
    • Steiner TS. How flagellin and toll-like receptor 5 contribute to enteric infection. Infect Immun 2007, 75:545-552. 10.1128/IAI.01506-06, 1828527, 17118981.
    • (2007) Infect Immun , vol.75 , pp. 545-552
    • Steiner, T.S.1
  • 5
    • 0035863730 scopus 로고    scopus 로고
    • Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: I kappa B alpha degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunction
    • Eaves-Pyles T, Murthy K, Liaudet L, Virag L, Ross G, Soriano FG, Szabo C, Salzman AL. Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: I kappa B alpha degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunction. J Immunol 2001, 166:1248-1260.
    • (2001) J Immunol , vol.166 , pp. 1248-1260
    • Eaves-Pyles, T.1    Murthy, K.2    Liaudet, L.3    Virag, L.4    Ross, G.5    Soriano, F.G.6    Szabo, C.7    Salzman, A.L.8
  • 7
    • 33947323718 scopus 로고    scopus 로고
    • TLRs in the Gut. III. Immune responses to flagellin in Crohn's disease: good, bad, or irrelevant?
    • 10.1152/ajpgi.00347.2006, 17038626
    • Gewirtz AT. TLRs in the Gut. III. Immune responses to flagellin in Crohn's disease: good, bad, or irrelevant?. Am J Physiol Gastrointest Liver Physiol 2007, 292:G706-710. 10.1152/ajpgi.00347.2006, 17038626.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Gewirtz, A.T.1
  • 8
    • 27144547642 scopus 로고    scopus 로고
    • Peroxynitrite is a potent inhibitor of NF-{kappa}B activation triggered by inflammatory stimuli in cardiac and endothelial cell lines
    • 10.1074/jbc.M501977200, 2225482, 16079150
    • Levrand S, Pesse B, Feihl F, Waeber B, Pacher P, Rolli J, Schaller MD, Liaudet L. Peroxynitrite is a potent inhibitor of NF-{kappa}B activation triggered by inflammatory stimuli in cardiac and endothelial cell lines. J Biol Chem 2005, 280:34878-34887. 10.1074/jbc.M501977200, 2225482, 16079150.
    • (2005) J Biol Chem , vol.280 , pp. 34878-34887
    • Levrand, S.1    Pesse, B.2    Feihl, F.3    Waeber, B.4    Pacher, P.5    Rolli, J.6    Schaller, M.D.7    Liaudet, L.8
  • 9
    • 17844362213 scopus 로고    scopus 로고
    • Peroxynitrite activates ERK via Raf-1 and MEK, independently from EGF receptor and p21(Ras) in H9C2 cardiomyocytes
    • 10.1016/j.yjmcc.2005.02.020, 2254583, 15850570
    • Pesse B, Levrand S, Feihl F, Waeber B, Gavillet B, Pacher P, Liaudet L. Peroxynitrite activates ERK via Raf-1 and MEK, independently from EGF receptor and p21(Ras) in H9C2 cardiomyocytes. J Mol Cell Cardiol 2005, 38:765-775. 10.1016/j.yjmcc.2005.02.020, 2254583, 15850570.
    • (2005) J Mol Cell Cardiol , vol.38 , pp. 765-775
    • Pesse, B.1    Levrand, S.2    Feihl, F.3    Waeber, B.4    Gavillet, B.5    Pacher, P.6    Liaudet, L.7
  • 10
    • 19644362276 scopus 로고    scopus 로고
    • Tissue-specific mRNA expression profiles of human toll-like receptors and related genes
    • 10.1248/bpb.28.886, 15863899
    • Nishimura M, Naito S. Tissue-specific mRNA expression profiles of human toll-like receptors and related genes. Biol Pharm Bull 2005, 28:886-892. 10.1248/bpb.28.886, 15863899.
    • (2005) Biol Pharm Bull , vol.28 , pp. 886-892
    • Nishimura, M.1    Naito, S.2
  • 11
    • 78651226166 scopus 로고    scopus 로고
    • Bacterial flagellin is a potent mediator of myocardial inflammation and cardiac dysfunction
    • Rolli J, Levrand S, Waeber B, Feihl F, Liaudet L. Bacterial flagellin is a potent mediator of myocardial inflammation and cardiac dysfunction. Intensive Care Med 2007, 33:S35.
    • (2007) Intensive Care Med , vol.33
    • Rolli, J.1    Levrand, S.2    Waeber, B.3    Feihl, F.4    Liaudet, L.5
  • 12
    • 26444440067 scopus 로고    scopus 로고
    • Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation
    • 10.1073/pnas.0502174102, 1224619, 16157881
    • Rhee SH, Im E, Riegler M, Kokkotou E, O'Brien M, Pothoulakis C. Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation. Proc Natl Acad Sci USA 2005, 102:13610-13615. 10.1073/pnas.0502174102, 1224619, 16157881.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 13610-13615
    • Rhee, S.H.1    Im, E.2    Riegler, M.3    Kokkotou, E.4    O'Brien, M.5    Pothoulakis, C.6
  • 13
    • 40249109853 scopus 로고    scopus 로고
    • The IkappaB kinase - a bridge between inflammation and cancer
    • 10.1038/cr.2008.30, 18301380
    • Karin M. The IkappaB kinase - a bridge between inflammation and cancer. Cell Res 2008, 18:334-342. 10.1038/cr.2008.30, 18301380.
    • (2008) Cell Res , vol.18 , pp. 334-342
    • Karin, M.1
  • 14
    • 59649117667 scopus 로고    scopus 로고
    • Molecular biology of inflammation and sepsis: a primer
    • 10.1097/CCM.0b013e31819267fb, 19050640
    • Cinel I, Opal SM. Molecular biology of inflammation and sepsis: a primer. Crit Care Med 2009, 37:291-304. 10.1097/CCM.0b013e31819267fb, 19050640.
    • (2009) Crit Care Med , vol.37 , pp. 291-304
    • Cinel, I.1    Opal, S.M.2
  • 15
    • 2942668829 scopus 로고    scopus 로고
    • Peptidoglycan and lipoteichoic acid in gram-positive bacterial sepsis: receptors, signal transduction, biological effects, and synergism
    • 10.1097/01.shk.0000092268.01859.0d, 14560103
    • Wang JE, Dahle MK, McDonald M, Foster SJ, Aasen AO, Thiemermann C. Peptidoglycan and lipoteichoic acid in gram-positive bacterial sepsis: receptors, signal transduction, biological effects, and synergism. Shock 2003, 20:402-414. 10.1097/01.shk.0000092268.01859.0d, 14560103.
    • (2003) Shock , vol.20 , pp. 402-414
    • Wang, J.E.1    Dahle, M.K.2    McDonald, M.3    Foster, S.J.4    Aasen, A.O.5    Thiemermann, C.6
  • 16
    • 77952355889 scopus 로고    scopus 로고
    • Oxidants positively or negatively regulate nuclear factor kappa B in a context-dependent manner
    • 10.1074/jbc.M110.103259, 20299457
    • Loukili N, Rosenblatt-Velin N, Rolli J, Levrand S, Feihl F, Waeber B, Pacher P, Liaudet L. Oxidants positively or negatively regulate nuclear factor kappa B in a context-dependent manner. J Biol Chem 2010, 285:15746-15752. 10.1074/jbc.M110.103259, 20299457.
    • (2010) J Biol Chem , vol.285 , pp. 15746-15752
    • Loukili, N.1    Rosenblatt-Velin, N.2    Rolli, J.3    Levrand, S.4    Feihl, F.5    Waeber, B.6    Pacher, P.7    Liaudet, L.8
  • 17
    • 33744533883 scopus 로고    scopus 로고
    • Parthenolide has limited effects on nuclear factor-kappa beta increases and worsens survival in lipopolysaccharide-challenged C57BL/6J mice
    • 10.1016/j.cyto.2006.03.002, 16720096
    • Li X, Cui X, Li Y, Fitz Y, Hsu L, Eichacker PQ. Parthenolide has limited effects on nuclear factor-kappa beta increases and worsens survival in lipopolysaccharide-challenged C57BL/6J mice. Cytokine 2006, 33:299-308. 10.1016/j.cyto.2006.03.002, 16720096.
    • (2006) Cytokine , vol.33 , pp. 299-308
    • Li, X.1    Cui, X.2    Li, Y.3    Fitz, Y.4    Hsu, L.5    Eichacker, P.Q.6
  • 19
    • 63649108380 scopus 로고    scopus 로고
    • The roles of TLRs, RLRs and NLRs in pathogen recognition
    • 10.1093/intimm/dxp017, 2721684, 19246554
    • Kawai T, Akira S. The roles of TLRs, RLRs and NLRs in pathogen recognition. Int Immunol 2009, 21:317-337. 10.1093/intimm/dxp017, 2721684, 19246554.
    • (2009) Int Immunol , vol.21 , pp. 317-337
    • Kawai, T.1    Akira, S.2
  • 20
    • 33750047495 scopus 로고    scopus 로고
    • Management of sepsis
    • 10.1056/NEJMra043632, 17050894
    • Russell JA. Management of sepsis. N Engl J Med 2006, 355:1699-1713. 10.1056/NEJMra043632, 17050894.
    • (2006) N Engl J Med , vol.355 , pp. 1699-1713
    • Russell, J.A.1
  • 22
    • 61549104663 scopus 로고    scopus 로고
    • Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice
    • 10.1186/1465-9921-10-6, 2644669, 19173740
    • Savale L, Tu L, Rideau D, Izziki M, Maitre B, Adnot S, Eddahibi S. Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice. Respir Res 2009, 10:6. 10.1186/1465-9921-10-6, 2644669, 19173740.
    • (2009) Respir Res , vol.10 , pp. 6
    • Savale, L.1    Tu, L.2    Rideau, D.3    Izziki, M.4    Maitre, B.5    Adnot, S.6    Eddahibi, S.7
  • 25
    • 77949897456 scopus 로고    scopus 로고
    • Year in review 2008: Critical Care--sepsis
    • 10.1186/cc7945, 2784335, 19886974
    • Opal SM, LaRosa SP. Year in review 2008: Critical Care--sepsis. Crit Care 2009, 13:224. 10.1186/cc7945, 2784335, 19886974.
    • (2009) Crit Care , vol.13 , pp. 224
    • Opal, S.M.1    LaRosa, S.P.2
  • 26
    • 10644237032 scopus 로고    scopus 로고
    • A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis
    • 10.1084/jem.20040708, 2211948, 15557347
    • Gibot S, Kolopp-Sarda MN, Bene MC, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis. J Exp Med 2004, 200:1419-1426. 10.1084/jem.20040708, 2211948, 15557347.
    • (2004) J Exp Med , vol.200 , pp. 1419-1426
    • Gibot, S.1    Kolopp-Sarda, M.N.2    Bene, M.C.3    Bollaert, P.E.4    Lozniewski, A.5    Mory, F.6    Levy, B.7    Faure, G.C.8
  • 28
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • 10.1016/j.cell.2010.01.040, 20303873
    • Schroder K, Tschopp J. The inflammasomes. Cell 2010, 140:821-832. 10.1016/j.cell.2010.01.040, 20303873.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 29
    • 60749104683 scopus 로고    scopus 로고
    • The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
    • 10.1038/ni.1703, 2820724, 19221555
    • Franchi L, Eigenbrod T, Munoz-Planillo R, Nunez G. The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat Immunol 2009, 10:241-247. 10.1038/ni.1703, 2820724, 19221555.
    • (2009) Nat Immunol , vol.10 , pp. 241-247
    • Franchi, L.1    Eigenbrod, T.2    Munoz-Planillo, R.3    Nunez, G.4
  • 30
    • 34548679608 scopus 로고    scopus 로고
    • TLR5 and Ipaf: dual sensors of bacterial flagellin in the innate immune system
    • 10.1007/s00281-007-0078-z, 17690885
    • Miao EA, Andersen-Nissen E, Warren SE, Aderem A. TLR5 and Ipaf: dual sensors of bacterial flagellin in the innate immune system. Semin Immunopathol 2007, 29:275-288. 10.1007/s00281-007-0078-z, 17690885.
    • (2007) Semin Immunopathol , vol.29 , pp. 275-288
    • Miao, E.A.1    Andersen-Nissen, E.2    Warren, S.E.3    Aderem, A.4
  • 31
    • 33750288937 scopus 로고    scopus 로고
    • Apoptosis and caspases regulate death and inflammation in sepsis
    • 10.1038/nri1943, 17039247
    • Hotchkiss RS, Nicholson DW. Apoptosis and caspases regulate death and inflammation in sepsis. Nat Rev Immunol 2006, 6:813-822. 10.1038/nri1943, 17039247.
    • (2006) Nat Rev Immunol , vol.6 , pp. 813-822
    • Hotchkiss, R.S.1    Nicholson, D.W.2
  • 33
    • 0037012470 scopus 로고    scopus 로고
    • Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis
    • 10.1001/jama.287.13.1716, 11926897
    • Coopersmith CM, Stromberg PE, Dunne WM, Davis CG, Amiot DM, Buchman TG, Karl IE, Hotchkiss RS. Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis. JAMA 2002, 287:1716-1721. 10.1001/jama.287.13.1716, 11926897.
    • (2002) JAMA , vol.287 , pp. 1716-1721
    • Coopersmith, C.M.1    Stromberg, P.E.2    Dunne, W.M.3    Davis, C.G.4    Amiot, D.M.5    Buchman, T.G.6    Karl, I.E.7    Hotchkiss, R.S.8
  • 34
    • 33747598024 scopus 로고    scopus 로고
    • Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo
    • 10.1016/j.freeradbiomed.2006.04.034, 2228266, 16934671
    • Levrand S, Vannay-Bouchiche C, Pesse B, Pacher P, Feihl F, Waeber B, Liaudet L. Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo. Free Radic Biol Med 2006, 41:886-895. 10.1016/j.freeradbiomed.2006.04.034, 2228266, 16934671.
    • (2006) Free Radic Biol Med , vol.41 , pp. 886-895
    • Levrand, S.1    Vannay-Bouchiche, C.2    Pesse, B.3    Pacher, P.4    Feihl, F.5    Waeber, B.6    Liaudet, L.7
  • 36
    • 0031110570 scopus 로고    scopus 로고
    • Cecal ligation and puncture (CLP) induces apoptosis in thymus, spleen, lung, and gut by an endotoxin and TNF-independent pathway
    • 10.1097/00024382-199704000-00002, 9110409
    • Hiramatsu M, Hotchkiss RS, Karl IE, Buchman TG. Cecal ligation and puncture (CLP) induces apoptosis in thymus, spleen, lung, and gut by an endotoxin and TNF-independent pathway. Shock 1997, 7:247-253. 10.1097/00024382-199704000-00002, 9110409.
    • (1997) Shock , vol.7 , pp. 247-253
    • Hiramatsu, M.1    Hotchkiss, R.S.2    Karl, I.E.3    Buchman, T.G.4


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