Computational analysis of mTOR signaling pathway: Bifurcation, carcinogenesis, and drug discovery

Anticancer Research

Volumn 30, Issue 7, 2010, Pages 2683-2688

  Wang, Guanyu ^a   Krueger, Gerhard R F ^b  

^a GEORGE WASHINGTON UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Bistable switch; Drug composition; Mathematical model; Response curve

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PROTEIN KINASE B INHIBITOR;

ARTICLE; CARCINOGENESIS; COMPUTER SIMULATION; DRUG RESEARCH; ENZYME INHIBITION; GEOMETRY; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; NEGATIVE FEEDBACK; PATHOGENESIS; PHENOTYPE; POSITIVE FEEDBACK; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ALGORITHMS; ANTINEOPLASTIC AGENTS; CELL TRANSFORMATION, NEOPLASTIC; COMPUTER SIMULATION; DRUG DELIVERY SYSTEMS; DRUG DISCOVERY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 77955791932     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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