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Volumn 161, Issue 1, 2010, Pages 79-91

Selective inhibition of persistent sodium current by F 15845 prevents ischaemia-induced arrhythmias

Author keywords

anti arrhythmia agents; F 15845; ion channels; ischaemia, pharmacology

Indexed keywords

ACONITINE; ANTIANGINA PECTORIS AGENT; ANTIARRHYTHMIC AGENT; F 15845; SODIUM CHANNEL; UNCLASSIFIED DRUG; VERATRIDINE;

EID: 77955785877     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00884.x     Document Type: Article
Times cited : (31)

References (41)
  • 2
    • 33745368556 scopus 로고    scopus 로고
    • Inhibition of the late sodium current as a potential cardioprotective principle: Effects of the late sodium current inhibitor ranolazine
    • Belardinelli L, Shryock JC, Fraser H (2006). Inhibition of the late sodium current as a potential cardioprotective principle: effects of the late sodium current inhibitor ranolazine. Heart 92 (Suppl. IV iv6 iv14.
    • (2006) Heart , vol.92 , Issue.SUPPL. IV
    • Belardinelli, L.1    Shryock, J.C.2    Fraser, H.3
  • 3
    • 0029097799 scopus 로고
    • Molecular mechanism for an inherited cardiac arrhythmia
    • Bennett PB, Yazawa K, Makita N, George AL Jr. (1995). Molecular mechanism for an inherited cardiac arrhythmia. Nature 376 : 683 685.
    • (1995) Nature , vol.376 , pp. 683-685
    • Bennett, P.B.1    Yazawa, K.2    Makita, N.3    George, Jr.A.L.4
  • 4
    • 0027940003 scopus 로고
    • Early afterdepolarization formation in cardiac myocytes: Analysis of phase plane patterns, action potential, and membrane currents
    • Boutjdir M, Restivo M, Wei Y, Stergiopoulos K, El-Sherif N (1994). Early afterdepolarization formation in cardiac myocytes: analysis of phase plane patterns, action potential, and membrane currents. J Cardiovasc Electrophysiol 7 : 609 620.
    • (1994) J Cardiovasc Electrophysiol , vol.7 , pp. 609-620
    • Boutjdir, M.1    Restivo, M.2    Wei, Y.3    Stergiopoulos, K.4    El-Sherif, N.5
  • 5
    • 0023138096 scopus 로고
    • Slow inactivation of the sodium current in rabbit cardiac Purkinje fibres
    • Carmeliet E (1987). Slow inactivation of the sodium current in rabbit cardiac Purkinje fibres. Pflugers Arch 408 : 18 26.
    • (1987) Pflugers Arch , vol.408 , pp. 18-26
    • Carmeliet, E.1
  • 6
    • 0011125529 scopus 로고
    • Role of the 'Na window' current and other ionic currents in triggering early after-depolarizations and resulting re-excitation in Purkinje fibers
    • Zipes, D.P. Jalife, J. eds). Grune and Stratton. New York
    • Coulombe A, Coraboeuf E, Malecot C, Deroubaix E (1985). Role of the 'Na window' current and other ionic currents in triggering early after-depolarizations and resulting re-excitation in Purkinje fibers. In : Zipes DP, Jalife J (eds). Cardiac Electrophysiology and Arrhythmias. Grune and Stratton : New York, pp. 43 49.
    • (1985) Cardiac Electrophysiology and Arrhythmias. , pp. 43-49
    • Coulombe, A.1    Coraboeuf, E.2    Malecot, C.3    Deroubaix, E.4
  • 7
    • 33751337747 scopus 로고    scopus 로고
    • + channels promote pause-induced spontaneous diastolic activity in long QT syndrome Type 3 myocytes
    • + channels promote pause-induced spontaneous diastolic activity in long QT syndrome Type 3 myocytes. Circ Res 99 : 1225 1232.
    • (2006) Circ Res , vol.99 , pp. 1225-1232
    • Fredj, S.1    Lindegger, N.2    Sampson, K.J.3    Carmeliet, P.4    Kass, R.S.5
  • 8
    • 0021256845 scopus 로고
    • Slow inactivation of a tetrodotoxin-sensitive current in canine cardiac Purkinje fibers
    • Gintant GA, Datyner NB, Cohen IS (1984). Slow inactivation of a tetrodotoxin-sensitive current in canine cardiac Purkinje fibers. Biophys J 45 : 509 512.
    • (1984) Biophys J , vol.45 , pp. 509-512
    • Gintant, G.A.1    Datyner, N.B.2    Cohen, I.S.3
  • 9
    • 0028298795 scopus 로고
    • Sodium channel blockade reduces hypoxic sodium loading and sodium-dependent calcium loading
    • Haigney MC, Lakatta EG, Stern MD, Silverman HS (1994). Sodium channel blockade reduces hypoxic sodium loading and sodium-dependent calcium loading. Circulation 90 : 391 399.
    • (1994) Circulation , vol.90 , pp. 391-399
    • Haigney, M.C.1    Lakatta, E.G.2    Stern, M.D.3    Silverman, H.S.4
  • 11
    • 0036736366 scopus 로고    scopus 로고
    • Hypoxia and persistent sodium current
    • Hammarstrom AK, Gage PW (2002). Hypoxia and persistent sodium current. Eur Biophys J 31 : 323 330.
    • (2002) Eur Biophys J , vol.31 , pp. 323-330
    • Hammarstrom, A.K.1    Gage, P.W.2
  • 12
    • 41549102140 scopus 로고    scopus 로고
    • Mechanism of action of the new anti-ischaemia drug ranolazine
    • Hasenfuss G, Maier LS (2008). Mechanism of action of the new anti-ischaemia drug ranolazine. Clin Res Cardiol 97 : 222 226.
    • (2008) Clin Res Cardiol , vol.97 , pp. 222-226
    • Hasenfuss, G.1    Maier, L.S.2
  • 14
    • 0029952835 scopus 로고    scopus 로고
    • Hypoxia increases persistent sodium current in rat ventricular myocytes
    • Ju YK, Saint DA, Gage PW (1996). Hypoxia increases persistent sodium current in rat ventricular myocytes. J Physiol 497 : 337 341.
    • (1996) J Physiol , vol.497 , pp. 337-341
    • Ju, Y.K.1    Saint, D.A.2    Gage, P.W.3
  • 16
    • 0034115443 scopus 로고    scopus 로고
    • Lubeluzole-induced prolongation of cardiac action potential in rabbit Purkinje Fibres
    • Le Grand B, Dordain-Maffre M, John GW (2000). Lubeluzole-induced prolongation of cardiac action potential in rabbit Purkinje Fibres. Fundam Clin Pharmacol 14 : 159 162.
    • (2000) Fundam Clin Pharmacol , vol.14 , pp. 159-162
    • Le Grand, B.1    Dordain-Maffre, M.2    John, G.W.3
  • 17
    • 46849116203 scopus 로고    scopus 로고
    • Sodium late current blockers in ischaemia reperfusion: Is the bullet magic?
    • Le Grand B, Pignier C, Létienne R, Cuisiat F, Rolland F, Mas A et al. (2008). Sodium late current blockers in ischaemia reperfusion: is the bullet magic? J Med Chem 51 : 3856 3866.
    • (2008) J Med Chem , vol.51 , pp. 3856-3866
    • Le Grand, B.1    Pignier, C.2    Létienne, R.3    Cuisiat, F.4    Rolland, F.5    Mas, A.6
  • 18
    • 0017031594 scopus 로고
    • Transient inward current underlying arrhythmogenic effects of cardiotonic steroids in Purkinje fibers
    • Lederer WJ, Tsien RW (1976). Transient inward current underlying arrhythmogenic effects of cardiotonic steroids in Purkinje fibers. J Physiol 263 : 73 100.
    • (1976) J Physiol , vol.263 , pp. 73-100
    • Lederer, W.J.1    Tsien, R.W.2
  • 19
    • 42749091983 scopus 로고    scopus 로고
    • Late sodium current in failing heart: Friend or foe?
    • Maltsev VA, Undrovinas A (2008). Late sodium current in failing heart: friend or foe? Prog Biophys Mol Biol 96 : 421 451.
    • (2008) Prog Biophys Mol Biol , vol.96 , pp. 421-451
    • Maltsev, V.A.1    Undrovinas, A.2
  • 20
    • 33745392178 scopus 로고    scopus 로고
    • Late sodium current in the pathophysiology of cardiovascular disease: Consequences of sodium-calcium overload
    • Noble D, Noble PJ (2006). Late sodium current in the pathophysiology of cardiovascular disease: consequences of sodium-calcium overload. Heart 92 : iv1 iv5.
    • (2006) Heart , vol.92
    • Noble, D.1    Noble, P.J.2
  • 21
    • 35348865551 scopus 로고    scopus 로고
    • Direct protective effects of poly-unsaturated fatty acids, DHA and EPA, against activation of cardiac late sodium current: A mechanism for ischaemia selectivity
    • Pignier C, Revenaz C, Rauly-Lestienne I, Cussac D, Delhon A, Gardette J et al. (2007). Direct protective effects of poly-unsaturated fatty acids, DHA and EPA, against activation of cardiac late sodium current: a mechanism for ischaemia selectivity. Basic Res Cardiol 102 : 553 564.
    • (2007) Basic Res Cardiol , vol.102 , pp. 553-564
    • Pignier, C.1    Revenaz, C.2    Rauly-Lestienne, I.3    Cussac, D.4    Delhon, A.5    Gardette, J.6
  • 22
    • 44249103991 scopus 로고    scopus 로고
    • Protease-activated receptor-1 mediates thrombin-induced persistent sodium current in human cardiomyocytes
    • Pinet C, Algalarrondo V, Sablayrolles S, Le Grand B, Pignier C, Cussac D et al. (2008). Protease-activated receptor-1 mediates thrombin-induced persistent sodium current in human cardiomyocytes. Mol Pharmacol 73 : 1622 1631.
    • (2008) Mol Pharmacol , vol.73 , pp. 1622-1631
    • Pinet, C.1    Algalarrondo, V.2    Sablayrolles, S.3    Le Grand, B.4    Pignier, C.5    Cussac, D.6
  • 23
    • 40949122385 scopus 로고    scopus 로고
    • Inhibition of late sodium current to reduce electrical and mechanical dysfunction of ischaemic myocardium
    • Shryock JC, Belardinelli L (2008). Inhibition of late sodium current to reduce electrical and mechanical dysfunction of ischaemic myocardium. Br J Pharmacol 153 : 1128 1132.
    • (2008) Br J Pharmacol , vol.153 , pp. 1128-1132
    • Shryock, J.C.1    Belardinelli, L.2
  • 24
    • 3242778566 scopus 로고    scopus 로고
    • Antagonism by ranolazine of the pro-arrhythmic effect of increase late Ina in guinea pig ventricular myocytes
    • Song Y, Shryock JC, Wu L, Belardinelli L (2004). Antagonism by ranolazine of the pro-arrhythmic effect of increase late Ina in guinea pig ventricular myocytes. J Cardiovasc Pharmacol 44 : 192 199.
    • (2004) J Cardiovasc Pharmacol , vol.44 , pp. 192-199
    • Song, Y.1    Shryock, J.C.2    Wu, L.3    Belardinelli, L.4
  • 25
    • 33745251122 scopus 로고    scopus 로고
    • Blocking late sodium current reduces hydrogen peroxide-induced arrhythmogenic activity and contractile dysfunction
    • Song Y, Shryock JC, Wagner S, Maier LS, Belardinelli L (2006). Blocking late sodium current reduces hydrogen peroxide-induced arrhythmogenic activity and contractile dysfunction. J Pharmacol Exp Ther 318 : 214 222.
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 214-222
    • Song, Y.1    Shryock, J.C.2    Wagner, S.3    Maier, L.S.4    Belardinelli, L.5
  • 26
    • 44949176560 scopus 로고    scopus 로고
    • An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes
    • Song Y, Shryock JC, Belardinelli L (2008). An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes. Am J Physiol 294 : H2031 H2039.
    • (2008) Am J Physiol , vol.294
    • Song, Y.1    Shryock, J.C.2    Belardinelli, L.3
  • 27
    • 45549105581 scopus 로고    scopus 로고
    • Ranolazine improves dysfunction in isolated myocardium from failing human hearts: Role of late sodium current and intracellular ion accumulation
    • Sossalla S, Wagner S, Rasenack EC, Ruff H, Weber SL, Schöndube FA et al. (2008). Ranolazine improves dysfunction in isolated myocardium from failing human hearts: role of late sodium current and intracellular ion accumulation. J Mol Cell Cardiol 45 : 32 43.
    • (2008) J Mol Cell Cardiol , vol.45 , pp. 32-43
    • Sossalla, S.1    Wagner, S.2    Rasenack, E.C.3    Ruff, H.4    Weber, S.L.5    Schöndube, F.A.6
  • 29
    • 0036708255 scopus 로고    scopus 로고
    • Anti-ischaemic compound KC
    • 12291 prevents diastolic contracture in isolated atria by blockade of voltage-gated sodium channels
    • Tamareille S, Le Grand B, John GW, Feuvray D, Coulombe A (2002). Anti-ischaemic compound KC 12291 prevents diastolic contracture in isolated atria by blockade of voltage-gated sodium channels. J Cardiovasc Pharmacol 40 : 346 355.
    • (2002) J Cardiovasc Pharmacol , vol.40 , pp. 346-355
    • Tamareille, S.1    Le Grand, B.2    John, G.W.3    Feuvray, D.4    Coulombe, A.5
  • 30
    • 0025256097 scopus 로고
    • 2+ overload and impairs function in anoxic rat heart
    • 2+ overload and impairs function in anoxic rat heart. J Mol Cell Cardiol 22 : 57 72.
    • (1990) J Mol Cell Cardiol , vol.22 , pp. 57-72
    • Tani, M.1    Neely, J.R.2
  • 31
    • 0026666057 scopus 로고
    • Inward sodium current at resting potentials in single cardiac myocytes induced by the ischaemic metabolite lysophosphatidylcholine
    • Undrovinas AI, Fleidervish IA, Makielski JC (1992). Inward sodium current at resting potentials in single cardiac myocytes induced by the ischaemic metabolite lysophosphatidylcholine. Circ Res 71 : 1231 1241.
    • (1992) Circ Res , vol.71 , pp. 1231-1241
    • Undrovinas, A.I.1    Fleidervish, I.A.2    Makielski, J.C.3
  • 32
    • 33646007982 scopus 로고    scopus 로고
    • Ranolazine improves abnormal repolarization and contraction in left ventricular myocytes of dogs with heart failure by inhibiting late sodium current
    • Undrovinas AL, Belardinelli L, Undrovinas NA, Sabbah HN (2006). Ranolazine improves abnormal repolarization and contraction in left ventricular myocytes of dogs with heart failure by inhibiting late sodium current. J Cardiovasc Electrophysiol 17 : S169 S177.
    • (2006) J Cardiovasc Electrophysiol , vol.17
    • Undrovinas, A.L.1    Belardinelli, L.2    Undrovinas, N.A.3    Sabbah, H.N.4
  • 36
    • 85047679058 scopus 로고
    • The Lambeth Conventions: Guidelines for the study of arrhythmias in ischaemia infarction and reperfusion
    • Walker MJ, Curtis MJ, Hearse DJ, Campbell RW, Janse MJ, Yellon DM et al. (1988). The Lambeth Conventions: guidelines for the study of arrhythmias in ischaemia infarction and reperfusion. Cardiovasc Res 22 : 447 455.
    • (1988) Cardiovasc Res , vol.22 , pp. 447-455
    • Walker, M.J.1    Curtis, M.J.2    Hearse, D.J.3    Campbell, R.W.4    Janse, M.J.5    Yellon, D.M.6
  • 38
    • 0023902688 scopus 로고
    • Basis for tetrodotoxin and lidocaine effects on action potentials in dog ventricular myocytes
    • Wasserstrom JA, Salata JJ (1988). Basis for tetrodotoxin and lidocaine effects on action potentials in dog ventricular myocytes. Am J Physiol 254 : H1157 H1166.
    • (1988) Am J Physiol , vol.254
    • Wasserstrom, J.A.1    Salata, J.J.2
  • 39
    • 0028325970 scopus 로고
    • Palmitoyl carnitine modifies sodium currents and induces transient inward current in ventricular myocytes
    • Wu J, Corr PB (1994). Palmitoyl carnitine modifies sodium currents and induces transient inward current in ventricular myocytes. Am J Physiol 266 : H1034 H1046.
    • (1994) Am J Physiol , vol.266
    • Wu, J.1    Corr, P.B.2
  • 41
    • 50649110687 scopus 로고    scopus 로고
    • Pathophysiology and pharmacology of the cardiac 'late sodium current'
    • Zaza A, Belardinelli L, Shryock JC (2008). Pathophysiology and pharmacology of the cardiac 'late sodium current'. Pharmacol Ther 119 : 326 339.
    • (2008) Pharmacol Ther , vol.119 , pp. 326-339
    • Zaza, A.1    Belardinelli, L.2    Shryock, J.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.