메뉴 건너뛰기




Volumn 70, Issue 16, 2010, Pages 6497-6508

Genome-wide identification of PAX3-FKHR binding sites in rhabdomyosarcoma reveals candidate target genes important for development and cancer

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 4; HYBRID PROTEIN; SOMATOMEDIN C RECEPTOR; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR PAX3; ANAPLASTIC LYMPHOMA KINASE; FGFR4 PROTEIN, HUMAN; MYCN PROTEIN, HUMAN; MYOD PROTEIN; MYOD1 MYOGENIC DIFFERENTIATION PROTEIN; NUCLEAR PROTEIN; ONCOPROTEIN; PAX3-FKHR FUSION PROTEIN, HUMAN; PROTEIN TYROSINE KINASE;

EID: 77955739897     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-0582     Document Type: Article
Times cited : (187)

References (50)
  • 2
    • 36248952802 scopus 로고    scopus 로고
    • The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions
    • Buckingham M, Relaix F. The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions. Annu Rev Cell Dev Biol 2007;23:645-73.
    • (2007) Annu Rev Cell Dev Biol , vol.23 , pp. 645-673
    • Buckingham, M.1    Relaix, F.2
  • 3
    • 30144439616 scopus 로고    scopus 로고
    • A PANorama of PAX genes in cancer and development
    • Robson EJ, He SJ, Eccles MR. A PANorama of PAX genes in cancer and development. Nat Rev Cancer 2006;61:52-62.
    • (2006) Nat Rev Cancer , vol.61 , pp. 52-62
    • Robson, E.J.1    He, S.J.2    Eccles, M.R.3
  • 5
    • 34447287334 scopus 로고    scopus 로고
    • Skeletal muscle progenitor cells and the role of Pax genes
    • Buckingham M. Skeletal muscle progenitor cells and the role of Pax genes. C R Biol 2007;3306-7:530-3.
    • (2007) C R Biol , vol.3306-3307 , pp. 530-533
    • Buckingham, M.1
  • 6
    • 0035839886 scopus 로고    scopus 로고
    • Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma
    • Barr FG. Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma. Oncogene 2001;2040:5736-46.
    • (2001) Oncogene , vol.2040 , pp. 5736-5746
    • Barr, F.G.1
  • 7
    • 0020681679 scopus 로고
    • Incidence of childhood cancer: Experience of a decade in a population-based registry
    • Kramer S, Meadows AT, Jarrett P, Evans AE. Incidence of childhood cancer: experience of a decade in a population-based registry. J Natl Cancer Inst 1983;701:49-55.
    • (1983) J Natl Cancer Inst , vol.701 , pp. 49-55
    • Kramer, S.1    Meadows, A.T.2    Jarrett, P.3    Evans, A.E.4
  • 8
    • 0027521658 scopus 로고
    • Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma
    • Galili N, Davis RJ, Fredericks WJ, et al. Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma. Nat Genet 1993;53:230-5.
    • (1993) Nat Genet , vol.53 , pp. 230-235
    • Galili, N.1    Davis, R.J.2    Fredericks, W.J.3
  • 9
    • 0027534945 scopus 로고
    • Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma
    • Barr FG, Galili N, Holick J, Biegel JA, Rovera G, Emanuel BS. Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma. Nat Genet 1993;32:113-7.
    • (1993) Nat Genet , vol.32 , pp. 113-117
    • Barr, F.G.1    Galili, N.2    Holick, J.3    Biegel, J.A.4    Rovera, G.5    Emanuel, B.S.6
  • 10
    • 0028881603 scopus 로고
    • The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3
    • Fredericks WJ, Galili N, Mukhopadhyay S, et al. The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3. Mol Cell Biol 1995;153:1522-35.
    • (1995) Mol Cell Biol , vol.153 , pp. 1522-1535
    • Fredericks, W.J.1    Galili, N.2    Mukhopadhyay, S.3
  • 11
    • 0033614967 scopus 로고    scopus 로고
    • PAX3 and PAX7 exhibit conserved cis-acting transcription repression domains and utilize a common gain of function mechanism in alveolar rhabdomyosarcoma
    • Bennicelli JL, Advani S, Schafer BW, Barr FG. PAX3 and PAX7 exhibit conserved cis-acting transcription repression domains and utilize a common gain of function mechanism in alveolar rhabdomyosarcoma. Oncogene 1999;1830:4348-56.
    • (1999) Oncogene , vol.1830 , pp. 4348-4356
    • Bennicelli, J.L.1    Advani, S.2    Schafer, B.W.3    Barr, F.G.4
  • 12
    • 0347384010 scopus 로고    scopus 로고
    • The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo
    • Relaix F, Polimeni M, Rocancourt D, Ponzetto C, Schafer BW, Buckingham M. The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo. Genes Dev 2003;1723:2950-65.
    • (2003) Genes Dev , vol.1723 , pp. 2950-2965
    • Relaix, F.1    Polimeni, M.2    Rocancourt, D.3    Ponzetto, C.4    Schafer, B.W.5    Buckingham, M.6
  • 13
    • 7544243041 scopus 로고    scopus 로고
    • Alveolar rhabdomyosarcomas in conditional Pax3: Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function
    • Keller C, Arenkiel BR, Coffin CM, El-Bardeesy N, DePinho RA, Capecchi MR. Alveolar rhabdomyosarcomas in conditional Pax3: Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function. Genes Dev 2004;1821:2614-26.
    • (2004) Genes Dev , vol.1821 , pp. 2614-2626
    • Keller, C.1    Arenkiel, B.R.2    Coffin, C.M.3    El-Bardeesy, N.4    DePinho, R.A.5    Capecchi, M.R.6
  • 14
    • 0036605806 scopus 로고    scopus 로고
    • PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: A report from the Children's Oncology Group
    • Sorensen PH, Lynch JC, Qualman SJ, et al. PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group. J Clin Oncol 2002;2011:2672-9.
    • (2002) J Clin Oncol , vol.2011 , pp. 2672-2679
    • Sorensen, P.H.1    Lynch, J.C.2    Qualman, S.J.3
  • 15
    • 0026593562 scopus 로고
    • Regulatory elements that control the lineage-specific expression of myoD
    • Goldhamer DJ, Faerman A, Shani M, Emerson CP, Jr. Regulatory elements that control the lineage-specific expression of myoD. Science 1992;256:538-42.
    • (1992) Science , vol.256 , pp. 538-542
    • Goldhamer, D.J.1    Faerman, A.2    Shani, M.3    Emerson Jr., C.P.4
  • 16
    • 0028964343 scopus 로고
    • Embryonic activation of the myoD gene is regulated by a highly conserved distal control element
    • Goldhamer DJ, Brunk BP, Faerman A, King A, Shani M,Emerson CP, Jr. Embryonic activation of the myoD gene is regulated by a highly conserved distal control element. Development 1995;1213:637-49.
    • (1995) Development , vol.1213 , pp. 637-649
    • Goldhamer, D.J.1    Brunk, B.P.2    Faerman, A.3    King, A.4    Shani, M.5    Emerson Jr., C.P.6
  • 17
    • 33748281725 scopus 로고    scopus 로고
    • A novel genetic hierarchy functions during hypaxial myogenesis: Pax3 directly activates Myf5 in muscle progenitor cells in the limb
    • Bajard L, Relaix F, Lagha M, Rocancourt D, Daubas P, Buckingham ME. A novel genetic hierarchy functions during hypaxial myogenesis: Pax3 directly activates Myf5 in muscle progenitor cells in the limb. Genes Dev 2006;2017:2450-64.
    • (2006) Genes Dev , vol.2017 , pp. 2450-2464
    • Bajard, L.1    Relaix, F.2    Lagha, M.3    Rocancourt, D.4    Daubas, P.5    Buckingham, M.E.6
  • 18
    • 0033740047 scopus 로고    scopus 로고
    • Modular long-range regulation of Myf5 reveals unexpected heterogeneity between skeletal muscles in the mouse embryo
    • 12720
    • Hadchouel J, Tajbakhsh S, Primig M, et al. Modular long-range regulation of Myf5 reveals unexpected heterogeneity between skeletal muscles in the mouse embryo. Development 2000;12720:4455-67.
    • (2000) Development , pp. 4455-4467
    • Hadchouel, J.1    Tajbakhsh, S.2    Primig, M.3
  • 19
    • 54249157471 scopus 로고    scopus 로고
    • Addiction to elevated insulin-like growth factor I receptor and initial modulation of the AKT pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody
    • Cao L, Yu Y, Darko I, et al. Addiction to elevated insulin-like growth factor I receptor and initial modulation of the AKT pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody. Cancer Res 2008;6819:8039-48.
    • (2008) Cancer Res , vol.6819 , pp. 8039-8048
    • Cao, L.1    Yu, Y.2    Darko, I.3
  • 20
    • 33750442923 scopus 로고    scopus 로고
    • Genome-wide analysis of estrogen receptor binding sites
    • Carroll JS, Meyer CA, Song J, et al. Genome-wide analysis of estrogen receptor binding sites. Nat Genet 2006;3811:1289-97.
    • (2006) Nat Genet , vol.3811 , pp. 1289-1297
    • Carroll, J.S.1    Meyer, C.A.2    Song, J.3
  • 21
    • 30344478870 scopus 로고    scopus 로고
    • A global map of p53 transcription-factor binding sites in the human genome
    • Wei CL, Wu Q, Vega VB, et al. A global map of p53 transcription-factor binding sites in the human genome. Cell 2006;1241:207-19.
    • (2006) Cell , vol.1241 , pp. 207-219
    • Wei, C.L.1    Wu, Q.2    Vega, V.B.3
  • 22
    • 34247369851 scopus 로고    scopus 로고
    • A homeo-paired domain-binding motif directs Myf5 expression in progenitor cells of limb muscle
    • Buchberger A, Freitag D, Arnold HH. A homeo-paired domain-binding motif directs Myf5 expression in progenitor cells of limb muscle. Development 2007;1346:1171-80.
    • (2007) Development , vol.1346 , pp. 1171-1180
    • Buchberger, A.1    Freitag, D.2    Arnold, H.H.3
  • 23
    • 33746895755 scopus 로고    scopus 로고
    • Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas
    • Davicioni E, Finckenstein FG, Shahbazian V, Buckley JD, Triche TJ, Anderson MJ. Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas. Cancer Res 2006;6614:6936-46.
    • (2006) Cancer Res , vol.6614 , pp. 6936-6946
    • Davicioni, E.1    Finckenstein, F.G.2    Shahbazian, V.3    Buckley, J.D.4    Triche, T.J.5    Anderson, M.J.6
  • 24
    • 59649085853 scopus 로고    scopus 로고
    • Molecular classification of rhabdomyosarcoma-genotypic and phenotypic determinants of diagnosis: A report from the Children's Oncology Group
    • Davicioni E, Anderson MJ, Finckenstein FG, et al. Molecular classification of rhabdomyosarcoma-genotypic and phenotypic determinants of diagnosis: a report from the Children's Oncology Group. Am J Pathol 2009;1742:550-64.
    • (2009) Am J Pathol , vol.1742 , pp. 550-564
    • Davicioni, E.1    Anderson, M.J.2    Finckenstein, F.G.3
  • 25
    • 0025853876 scopus 로고
    • MyoD and the regulation of myogenesis by helix-loop-helix proteins
    • Tapscott SJ, Weintraub H. MyoD and the regulation of myogenesis by helix-loop-helix proteins. J Clin Invest 1991;874:1133-8.
    • (1991) J Clin Invest , vol.874 , pp. 1133-1138
    • Tapscott, S.J.1    Weintraub, H.2
  • 26
    • 0032967747 scopus 로고    scopus 로고
    • Fine-scale transgenic mapping of the MyoD core enhancer: MyoD is regulated by distinct but overlapping mechanisms in myotomal and non-myotomal muscle lineages
    • Kucharczuk KL, Love CM, Dougherty NM, Goldhamer DJ. Fine-scale transgenic mapping of the MyoD core enhancer: MyoD is regulated by distinct but overlapping mechanisms in myotomal and non-myotomal muscle lineages. Development 1999;1269:1957-65.
    • (1999) Development , vol.1269 , pp. 1957-1965
    • Kucharczuk, K.L.1    Love, C.M.2    Dougherty, N.M.3    Goldhamer, D.J.4
  • 27
    • 0030891169 scopus 로고    scopus 로고
    • Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD
    • Tajbakhsh S, Rocancourt D, Cossu G, Buckingham M. Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD. Cell 1997;891:127-38.
    • (1997) Cell , vol.891 , pp. 127-138
    • Tajbakhsh, S.1    Rocancourt, D.2    Cossu, G.3    Buckingham, M.4
  • 28
    • 13444273342 scopus 로고    scopus 로고
    • Identifying tissue-selective transcription factor binding sites in vertebrate promoters
    • Smith AD, Sumazin P, Zhang MQ. Identifying tissue-selective transcription factor binding sites in vertebrate promoters. Proc Natl Acad Sci U S A 2005;1025:1560-5.
    • (2005) Proc Natl Acad Sci U S A , vol.1025 , pp. 1560-1565
    • Smith, A.D.1    Sumazin, P.2    Zhang, M.Q.3
  • 29
    • 33748419667 scopus 로고    scopus 로고
    • Myogenic progenitor cells and skeletal myogenesis in vertebrates
    • Buckingham M. Myogenic progenitor cells and skeletal myogenesis in vertebrates. Curr Opin Genet Dev 2006;165:525-32.
    • (2006) Curr Opin Genet Dev , vol.165 , pp. 525-532
    • Buckingham, M.1
  • 30
    • 46249087227 scopus 로고    scopus 로고
    • Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic program
    • Lagha M, Kormish JD, Rocancourt D, et al. Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic program. Genes Dev 2008;2213:1828-37.
    • (2008) Genes Dev , vol.2213 , pp. 1828-1837
    • Lagha, M.1    Kormish, J.D.2    Rocancourt, D.3
  • 31
    • 70449450426 scopus 로고    scopus 로고
    • Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models
    • 11911
    • Taylor JG, Cheuk AT, Tsang PS, et al. Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models. J Clin Invest 2009;11911:3395-407.
    • (2009) J Clin Invest , pp. 3395-3407
    • Taylor, J.G.1    Cheuk, A.T.2    Tsang, P.S.3
  • 33
    • 20044391414 scopus 로고    scopus 로고
    • Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype
    • Williamson D, Lu YJ, Gordon T, et al. Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype. J Clin Oncol 2005;234:880-8.
    • (2005) J Clin Oncol , vol.234 , pp. 880-888
    • Williamson, D.1    Lu, Y.J.2    Gordon, T.3
  • 34
    • 54049118823 scopus 로고    scopus 로고
    • Oncogenic mutations of ALK kinase in neuroblastoma
    • Chen Y, Takita J, Choi YL, et al. Oncogenic mutations of ALK kinase in neuroblastoma. Nature 2008;455:971-4.
    • (2008) Nature , vol.455 , pp. 971-974
    • Chen, Y.1    Takita, J.2    Choi, Y.L.3
  • 35
    • 54049120220 scopus 로고    scopus 로고
    • Activating mutations in ALK provide a therapeutic target in neuroblastoma
    • George RE, Sanda T, Hanna M, et al. Activating mutations in ALK provide a therapeutic target in neuroblastoma. Nature 2008;455:975-8.
    • (2008) Nature , vol.455 , pp. 975-978
    • George, R.E.1    Sanda, T.2    Hanna, M.3
  • 36
    • 54049149961 scopus 로고    scopus 로고
    • Somatic and germ-line activating mutations of the ALK kinase receptor in neuroblastoma
    • Janoueix-Lerosey I, Lequin D, Brugieres L, et al. Somatic and germ-line activating mutations of the ALK kinase receptor in neuroblastoma. Nature 2008;455:967-70.
    • (2008) Nature , vol.455 , pp. 967-970
    • Janoueix-Lerosey, I.1    Lequin, D.2    Brugieres, L.3
  • 37
    • 54049094708 scopus 로고    scopus 로고
    • Identification of ALK as a major familial neuroblastoma predisposition gene
    • Mosse YP, Laudenslager M, Longo L, et al. Identification of ALK as a major familial neuroblastoma predisposition gene. Nature 2008;455:930-5.
    • (2008) Nature , vol.455 , pp. 930-935
    • Mosse, Y.P.1    Laudenslager, M.2    Longo, L.3
  • 38
    • 29944432793 scopus 로고    scopus 로고
    • Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells
    • Relaix F, Montarras D, Zaffran S, et al. Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells. J Cell Biol 2006;1721:91-102.
    • (2006) J Cell Biol , vol.1721 , pp. 91-102
    • Relaix, F.1    Montarras, D.2    Zaffran, S.3
  • 39
    • 20544441737 scopus 로고    scopus 로고
    • A Pax3/Pax7-dependent population of skeletal muscle progenitor cells
    • Relaix F, Rocancourt D, Mansouri A, Buckingham M. A Pax3/Pax7-dependent population of skeletal muscle progenitor cells. Nature 2005;435:948-53.
    • (2005) Nature , vol.435 , pp. 948-953
    • Relaix, F.1    Rocancourt, D.2    Mansouri, A.3    Buckingham, M.4
  • 40
    • 0033539498 scopus 로고    scopus 로고
    • cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene
    • Khan J, Bittner ML, Saal LH, et al. cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene. Proc Natl Acad Sci U S A 1999;9623:13264-9.
    • (1999) Proc Natl Acad Sci U S A , vol.9623 , pp. 13264-13269
    • Khan, J.1    Bittner, M.L.2    Saal, L.H.3
  • 41
    • 0036196163 scopus 로고    scopus 로고
    • Identification of target genes regulated by PAX3 and PAX3-FKHR in embryogenesis and alveolar rhabdomyosarcoma
    • Barber TD, Barber MC, Tomescu O, Barr FG, Ruben S, Friedman TB. Identification of target genes regulated by PAX3 and PAX3-FKHR in embryogenesis and alveolar rhabdomyosarcoma. Genomics 2002;793:278-84.
    • (2002) Genomics , vol.793 , pp. 278-284
    • Barber, T.D.1    Barber, M.C.2    Tomescu, O.3    Barr, F.G.4    Ruben, S.5    Friedman, T.B.6
  • 42
    • 16244385890 scopus 로고    scopus 로고
    • Cell-type-specific regulation of distinct sets of gene targets by Pax3 and Pax3/FKHR
    • Begum S, Emami N, Cheung A, Wilkins O, Der S, Hamel PA. Cell-type-specific regulation of distinct sets of gene targets by Pax3 and Pax3/FKHR. Oncogene 2005;2411:1860-72.
    • (2005) Oncogene , vol.2411 , pp. 1860-1872
    • Begum, S.1    Emami, N.2    Cheung, A.3    Wilkins, O.4    Hamel Pa, D.S.5
  • 43
    • 0031861728 scopus 로고    scopus 로고
    • Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor α receptor
    • Epstein JA, Song B, Lakkis M, Wang C. Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor α receptor. Mol Cell Biol 1998;187:4118-30.
    • (1998) Mol Cell Biol , vol.187 , pp. 4118-4130
    • Epstein, J.A.1    Song, B.2    Lakkis, M.3    Wang, C.4
  • 44
    • 75149142302 scopus 로고    scopus 로고
    • Regulation of expression of stromal-derived factor-1 receptors: CXCR4 and CXCR7 in human rhabdomyosarcomas
    • Tarnowski M, Grymula K, Reca R, et al. Regulation of expression of stromal-derived factor-1 receptors: CXCR4 and CXCR7 in human rhabdomyosarcomas. Mol Cancer Res 2010;81:1-14.
    • (2010) Mol Cancer Res , vol.81 , pp. 1-14
    • Tarnowski, M.1    Grymula, K.2    Reca, R.3
  • 45
    • 33947158748 scopus 로고    scopus 로고
    • Identification of a new class of PAX3-FKHR target promoters: A role of the Pax3 paired box DNA binding domain
    • Zhang L, Wang C. Identification of a new class of PAX3-FKHR target promoters: a role of the Pax3 paired box DNA binding domain. Oncogene 2007;2611:1595-605.
    • (2007) Oncogene , vol.2611 , pp. 1595-1605
    • Zhang, L.1    Wang, C.2
  • 46
    • 0027099864 scopus 로고
    • Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos
    • Candia AF, Hu J, Crosby J, et al. Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos. Development 1992;1164:1123-36.
    • (1992) Development , vol.1164 , pp. 1123-1136
    • Candia, A.F.1    Hu, J.2    Crosby, J.3
  • 47
    • 0033167972 scopus 로고    scopus 로고
    • Mox2 is a component of the genetic hierarchy controlling limb muscle development
    • Mankoo BS, Collins NS, Ashby P, et al. Mox2 is a component of the genetic hierarchy controlling limb muscle development. Nature 1999;400:69-73.
    • (1999) Nature , vol.400 , pp. 69-73
    • Mankoo, B.S.1    Collins, N.S.2    Ashby, P.3
  • 48
    • 0029026227 scopus 로고
    • The paired-like homeo box gene MHox is required for early events of skeletogenesis in multiple lineages
    • Martin JF, Bradley A, Olson EN. The paired-like homeo box gene MHox is required for early events of skeletogenesis in multiple lineages. Genes Dev 1995;910:1237-49.
    • (1995) Genes Dev , vol.910 , pp. 1237-1249
    • Martin, J.F.1    Bradley, A.2    Olson, E.N.3
  • 49
    • 0031040876 scopus 로고    scopus 로고
    • Pax3 is required for cardiac neural crest migration in the mouse: Evidence from the splotch (Sp2H) mutant
    • Conway SJ, Henderson DJ, Copp AJ. Pax3 is required for cardiac neural crest migration in the mouse: evidence from the splotch (Sp2H) mutant. Development 1997;1242:505-14.
    • (1997) Development , vol.1242 , pp. 505-514
    • Conway, S.J.1    Henderson, D.J.2    Copp, A.J.3
  • 50
    • 43049183354 scopus 로고    scopus 로고
    • Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: Focus on MYCN as a biologically relevant target
    • Mercado GE, Xia SJ, Zhang C, et al. Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: focus on MYCN as a biologically relevant target. Genes Chromosomes Cancer 2008;476:510-20.
    • (2008) Genes Chromosomes Cancer , vol.476 , pp. 510-520
    • Mercado, G.E.1    Xia, S.J.2    Zhang, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.