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Volumn 20, Issue 5, 2010, Pages 332-340

Efficacy of genistein aglycone on some cardiovascular risk factors and homocysteine levels: A follow-up study

Author keywords

Cardiovascular risk; Genistein; Homocysteine; Menopause

Indexed keywords

CALCIUM CARBONATE; COLECALCIFEROL; GENISTEIN; HOMOCYSTEINE; LIPID; OSTEOPROTEGERIN;

EID: 77955693086     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2009.04.012     Document Type: Article
Times cited : (61)

References (44)
  • 1
    • 34250772239 scopus 로고    scopus 로고
    • Sex hormones and the cardiovascular system: effects on arterial function in women
    • Teede H.J. Sex hormones and the cardiovascular system: effects on arterial function in women. Clin Exp Pharmacol Physiol 2007, 34:672-676.
    • (2007) Clin Exp Pharmacol Physiol , vol.34 , pp. 672-676
    • Teede, H.J.1
  • 2
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women's health initiative randomized controlled trial
    • Writing Group for the Women's Health Initiative Investigators
    • Rossouw J.E., Anderson G.L., Prentice R.L., LaCroix A.Z., Kooperberg C., Stefanick M.L., et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women's health initiative randomized controlled trial. JAMA 2002, 288:321-333. Writing Group for the Women's Health Initiative Investigators.
    • (2002) JAMA , vol.288 , pp. 321-333
    • Rossouw, J.E.1    Anderson, G.L.2    Prentice, R.L.3    LaCroix, A.Z.4    Kooperberg, C.5    Stefanick, M.L.6
  • 3
    • 41949105748 scopus 로고    scopus 로고
    • Treating cardiovascular disease in women
    • Taggu W., Lloyd G. Treating cardiovascular disease in women. Menopause Int 2007, 13:159-164.
    • (2007) Menopause Int , vol.13 , pp. 159-164
    • Taggu, W.1    Lloyd, G.2
  • 4
    • 0030976331 scopus 로고    scopus 로고
    • Phyto-oestrogens and Western diseases
    • Adlercreutz H., Mazur W. Phyto-oestrogens and Western diseases. Ann Med 1997, 29:95-120.
    • (1997) Ann Med , vol.29 , pp. 95-120
    • Adlercreutz, H.1    Mazur, W.2
  • 6
    • 36249025809 scopus 로고    scopus 로고
    • Isoflavones, equol and cardiovascular disease: pharmacological and therapeutic insights
    • Jackman K.A., Woodman O.L., Sobey C.G. Isoflavones, equol and cardiovascular disease: pharmacological and therapeutic insights. Curr Med Chem 2007, 14:2824-2830.
    • (2007) Curr Med Chem , vol.14 , pp. 2824-2830
    • Jackman, K.A.1    Woodman, O.L.2    Sobey, C.G.3
  • 7
    • 35548980921 scopus 로고    scopus 로고
    • Phytochemical genistein in the regulation of vascular function: new insights
    • Si H., Liu D. Phytochemical genistein in the regulation of vascular function: new insights. Curr Med Chem 2007, 14:2581-2589.
    • (2007) Curr Med Chem , vol.14 , pp. 2581-2589
    • Si, H.1    Liu, D.2
  • 8
    • 33751243628 scopus 로고    scopus 로고
    • Bioavailability of genistein and its glycoside genistin as measured in the portal vein of freely moving unanesthetized rats
    • Steensma A., Faassen-Peters M.A., Noteborn H.P., Rietjens I.M. Bioavailability of genistein and its glycoside genistin as measured in the portal vein of freely moving unanesthetized rats. J Agric Food Chem 2006, 54:8006-8012.
    • (2006) J Agric Food Chem , vol.54 , pp. 8006-8012
    • Steensma, A.1    Faassen-Peters, M.A.2    Noteborn, H.P.3    Rietjens, I.M.4
  • 9
    • 0035072990 scopus 로고    scopus 로고
    • Bioavailability of pure isoflavones in healthy humans and analysis of commercial soy isoflavone supplements
    • Setchell K.D., Brown N.M., Desai P., Zimmer-Nechemias L., Wolfe B.E., Brashear W.T. Bioavailability of pure isoflavones in healthy humans and analysis of commercial soy isoflavone supplements. J Nutr 2001, 131:1362S-1375S.
    • (2001) J Nutr , vol.131
    • Setchell, K.D.1    Brown, N.M.2    Desai, P.3    Zimmer-Nechemias, L.4    Wolfe, B.E.5    Brashear, W.T.6
  • 11
    • 34347383831 scopus 로고    scopus 로고
    • Effects of the phytoestrogen genistein on bone metabolism in osteopenic postmenopausal women: a randomized trial
    • Marini H., Minutoli L., Polito F., Bitto A., Altavilla D., Atteritano M., et al. Effects of the phytoestrogen genistein on bone metabolism in osteopenic postmenopausal women: a randomized trial. Ann Intern Med 2007, 146:839-847.
    • (2007) Ann Intern Med , vol.146 , pp. 839-847
    • Marini, H.1    Minutoli, L.2    Polito, F.3    Bitto, A.4    Altavilla, D.5    Atteritano, M.6
  • 12
    • 0036269245 scopus 로고    scopus 로고
    • The effect of the phytoestrogen genistein on plasma nitric oxide concentrations, endothelin-1 levels and endothelium dependent vasodilation in postmenopausal women
    • Squadrito F., Altavilla D., Morabito N., Crisafulli A., D'Anna R., Corrado F., et al. The effect of the phytoestrogen genistein on plasma nitric oxide concentrations, endothelin-1 levels and endothelium dependent vasodilation in postmenopausal women. Atherosclerosis 2002, 163:339-347.
    • (2002) Atherosclerosis , vol.163 , pp. 339-347
    • Squadrito, F.1    Altavilla, D.2    Morabito, N.3    Crisafulli, A.4    D'Anna, R.5    Corrado, F.6
  • 13
    • 34447300427 scopus 로고    scopus 로고
    • Effects of the phytoestrogen genistein on hot flushes, endometrium, and vaginal epithelium in postmenopausal women: a 1-year randomized, double-blind, placebo-controlled study
    • D'Anna R., Cannata M.L., Atteritano M., Cancellieri F., Corrado F., Baviera G., et al. Effects of the phytoestrogen genistein on hot flushes, endometrium, and vaginal epithelium in postmenopausal women: a 1-year randomized, double-blind, placebo-controlled study. Menopause 2007, 14:648-655.
    • (2007) Menopause , vol.14 , pp. 648-655
    • D'Anna, R.1    Cannata, M.L.2    Atteritano, M.3    Cancellieri, F.4    Corrado, F.5    Baviera, G.6
  • 14
    • 34547742675 scopus 로고    scopus 로고
    • Effects of the phytoestrogen genistein on some predictors of cardiovascular risk in osteopenic, postmenopausal women: a two-year randomized, double-blind, placebo-controlled study
    • Atteritano M., Marini H., Minutoli L., Polito F., Bitto A., Altavilla D., et al. Effects of the phytoestrogen genistein on some predictors of cardiovascular risk in osteopenic, postmenopausal women: a two-year randomized, double-blind, placebo-controlled study. J Clin Endocrinol Metab 2007, 92:3068-3075.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3068-3075
    • Atteritano, M.1    Marini, H.2    Minutoli, L.3    Polito, F.4    Bitto, A.5    Altavilla, D.6
  • 15
    • 57349142997 scopus 로고    scopus 로고
    • Breast safety and efficacy of genistein aglycone for post-menopausal bone loss: a follow-up study
    • Marini H., Bitto A., Altavilla D., Burnett B.P., Polito F., Di Stefano V., et al. Breast safety and efficacy of genistein aglycone for post-menopausal bone loss: a follow-up study. J Clin Endocrinol Metab 2008, 93:4787-4796.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 4787-4796
    • Marini, H.1    Bitto, A.2    Altavilla, D.3    Burnett, B.P.4    Polito, F.5    Di Stefano, V.6
  • 16
    • 33645213907 scopus 로고    scopus 로고
    • Isoflavones made simple-genistein's agonist activity for the beta-type estrogen receptor mediates their health benefits
    • McCarty M.F. Isoflavones made simple-genistein's agonist activity for the beta-type estrogen receptor mediates their health benefits. Med Hypotheses 2006, 66:1093-1114.
    • (2006) Med Hypotheses , vol.66 , pp. 1093-1114
    • McCarty, M.F.1
  • 17
    • 0031741906 scopus 로고    scopus 로고
    • Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones
    • Setchell K.D. Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones. Am J Clin Nutr 1998, 68:1333S-1346S.
    • (1998) Am J Clin Nutr , vol.68
    • Setchell, K.D.1
  • 18
    • 35448942379 scopus 로고    scopus 로고
    • Implications of phytoestrogen intake for breast cancer
    • Duffy C., Perez K., Partridge A. Implications of phytoestrogen intake for breast cancer. CA Cancer J Clin 2007, 57:260-277.
    • (2007) CA Cancer J Clin , vol.57 , pp. 260-277
    • Duffy, C.1    Perez, K.2    Partridge, A.3
  • 19
    • 33745078959 scopus 로고    scopus 로고
    • Phytoestrogens and cardiovascular disease
    • Cassidy A., Hooper L. Phytoestrogens and cardiovascular disease. J Br Menopause Soc 2006, 12:49-56.
    • (2006) J Br Menopause Soc , vol.12 , pp. 49-56
    • Cassidy, A.1    Hooper, L.2
  • 20
    • 33645050957 scopus 로고    scopus 로고
    • Soy protein, isoflavones, and cardiovascular health: an American Heart Association Science Advisory for professionals from the Nutrition Committee
    • American Heart Association Nutrition Committee
    • Sacks F.M., Lichtenstein A., Van Horn L., Harris W., Kris-Etherton P., Winston M. Soy protein, isoflavones, and cardiovascular health: an American Heart Association Science Advisory for professionals from the Nutrition Committee. Circulation 2006, 113:1034-1044. American Heart Association Nutrition Committee.
    • (2006) Circulation , vol.113 , pp. 1034-1044
    • Sacks, F.M.1    Lichtenstein, A.2    Van Horn, L.3    Harris, W.4    Kris-Etherton, P.5    Winston, M.6
  • 22
    • 0035854819 scopus 로고    scopus 로고
    • Genistein, a soy isoflavone, is a potent alpha-glucosidase inhibitor
    • Lee D.S., Lee S.H. Genistein, a soy isoflavone, is a potent alpha-glucosidase inhibitor. FEBS Lett 2001, 501:84-86.
    • (2001) FEBS Lett , vol.501 , pp. 84-86
    • Lee, D.S.1    Lee, S.H.2
  • 23
    • 38749085618 scopus 로고    scopus 로고
    • Genistein and daidzein prevent diabetes onset by elevating insulin level and altering hepatic gluconeogenic and lipogenic enzyme activities in non-obese diabetic (NOD) mice
    • Choi M.S., Jung U.J., Yeo J., Kim M.J., Lee M.K. Genistein and daidzein prevent diabetes onset by elevating insulin level and altering hepatic gluconeogenic and lipogenic enzyme activities in non-obese diabetic (NOD) mice. Diabetes Metab Res Rev 2008, 24:74-81.
    • (2008) Diabetes Metab Res Rev , vol.24 , pp. 74-81
    • Choi, M.S.1    Jung, U.J.2    Yeo, J.3    Kim, M.J.4    Lee, M.K.5
  • 24
    • 0034908730 scopus 로고    scopus 로고
    • Normalization of retinal vascular permeability in experimental diabetes with genistein
    • Nakajima M., Cooney M.J., Tu A.H., Chang K.Y., Cao J., Ando A., et al. Normalization of retinal vascular permeability in experimental diabetes with genistein. Invest Ophthalmol Vis Sci 2001, 42:2110-2114.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 2110-2114
    • Nakajima, M.1    Cooney, M.J.2    Tu, A.H.3    Chang, K.Y.4    Cao, J.5    Ando, A.6
  • 26
    • 33645641438 scopus 로고    scopus 로고
    • Soy-isoflavone-enriched foods and markers of lipid and glucose metabolism in postmenopausal women: interactions with genotype and equol production
    • Hall W.L., Vafeiadou K., Hallund J., Bugel S., Reimann M., Koebnick C., et al. Soy-isoflavone-enriched foods and markers of lipid and glucose metabolism in postmenopausal women: interactions with genotype and equol production. Am J Clin Nutr 2006, 83:592-600.
    • (2006) Am J Clin Nutr , vol.83 , pp. 592-600
    • Hall, W.L.1    Vafeiadou, K.2    Hallund, J.3    Bugel, S.4    Reimann, M.5    Koebnick, C.6
  • 27
    • 34347266963 scopus 로고    scopus 로고
    • The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis
    • Pittas A.G., Lau J., Hu F.B., Dawson-Hughes B. The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. J Clin Endocrinol Metab 2007, 92:2017-2029.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 2017-2029
    • Pittas, A.G.1    Lau, J.2    Hu, F.B.3    Dawson-Hughes, B.4
  • 29
    • 33644874487 scopus 로고    scopus 로고
    • Are tyrosine kinases involved in mediating contraction-stimulated muscle glucose transport?
    • Wright D.C., Geiger P.C., Han D.H., Holloszy J.O. Are tyrosine kinases involved in mediating contraction-stimulated muscle glucose transport?. Am J Physiol Endocrinol Metab 2006, 290:E123-E128.
    • (2006) Am J Physiol Endocrinol Metab , vol.290
    • Wright, D.C.1    Geiger, P.C.2    Han, D.H.3    Holloszy, J.O.4
  • 30
    • 0037428403 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR) as a molecular target for the soy phytoestrogen genistein
    • Dang Z.C., Audinot V., Papapoulos S.E., Boutin J.A., Löwik C.W. Peroxisome proliferator-activated receptor (PPAR) as a molecular target for the soy phytoestrogen genistein. J Biol Chem 2003, 278:962-967.
    • (2003) J Biol Chem , vol.278 , pp. 962-967
    • Dang, Z.C.1    Audinot, V.2    Papapoulos, S.E.3    Boutin, J.A.4    Löwik, C.W.5
  • 31
    • 14544279414 scopus 로고    scopus 로고
    • Meta-analysis of the effects of soy protein containing isoflavones on the lipid profile
    • Zhan S., Ho S.C. Meta-analysis of the effects of soy protein containing isoflavones on the lipid profile. Am J Clin Nutr 2005, 81:397-408.
    • (2005) Am J Clin Nutr , vol.81 , pp. 397-408
    • Zhan, S.1    Ho, S.C.2
  • 32
    • 0037015255 scopus 로고    scopus 로고
    • Serum osteoprotegerin levels are associated with the presence and severity of coronary artery disease
    • Jono S., Ikari Y., Shioi A., Mori K., Miki T., Hara K., et al. Serum osteoprotegerin levels are associated with the presence and severity of coronary artery disease. Circulation 2002, 106:1192-1194.
    • (2002) Circulation , vol.106 , pp. 1192-1194
    • Jono, S.1    Ikari, Y.2    Shioi, A.3    Mori, K.4    Miki, T.5    Hara, K.6
  • 33
    • 0034698926 scopus 로고    scopus 로고
    • Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis
    • Min H., Morony S., Sarosi I., Dunstan C.R., Capparelli C., Scully S., et al. Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis. J Exp Med 2000, 192:463-474.
    • (2000) J Exp Med , vol.192 , pp. 463-474
    • Min, H.1    Morony, S.2    Sarosi, I.3    Dunstan, C.R.4    Capparelli, C.5    Scully, S.6
  • 34
    • 0023644095 scopus 로고
    • Fibrinogen and the risk of cardiovascular disease: the Framingham Study
    • Kannel W.B., Wolf P.A., Castelli W.P., D'Agostino R.B. Fibrinogen and the risk of cardiovascular disease: the Framingham Study. J Am Med Assoc 1987, 258:1183-1186.
    • (1987) J Am Med Assoc , vol.258 , pp. 1183-1186
    • Kannel, W.B.1    Wolf, P.A.2    Castelli, W.P.3    D'Agostino, R.B.4
  • 35
    • 0036164830 scopus 로고    scopus 로고
    • Markers of inflammation and coronary artery disease
    • Saadeddin S.M., Habbab M.A., Ferns G.A. Markers of inflammation and coronary artery disease. Med Sci Monit 2002, 8:5-12.
    • (2002) Med Sci Monit , vol.8 , pp. 5-12
    • Saadeddin, S.M.1    Habbab, M.A.2    Ferns, G.A.3
  • 37
    • 0036071278 scopus 로고    scopus 로고
    • Effect of long-term hormone replacement therapy on plasma homocysteine in postmenopausal women: a randomized controlled study
    • Madsen J.S., Kristensen S.R., Klitgaard N.A., Bladbjerg E.M., Abrahamsen B., Stilgren L., et al. Effect of long-term hormone replacement therapy on plasma homocysteine in postmenopausal women: a randomized controlled study. Am J Obstet Gynecol 2002, 187:33-39.
    • (2002) Am J Obstet Gynecol , vol.187 , pp. 33-39
    • Madsen, J.S.1    Kristensen, S.R.2    Klitgaard, N.A.3    Bladbjerg, E.M.4    Abrahamsen, B.5    Stilgren, L.6
  • 38
    • 33750631885 scopus 로고    scopus 로고
    • Effects of soy isoflavones and phytate on homocysteine, C-reactive protein, and iron status in postmenopausal women
    • Hanson L.N., Engelman H.M., Alekel D.L., Schalinske K.L., Kohut M.L., Reddy M.B. Effects of soy isoflavones and phytate on homocysteine, C-reactive protein, and iron status in postmenopausal women. Am J Clin Nutr 2006, 84:774-780.
    • (2006) Am J Clin Nutr , vol.84 , pp. 774-780
    • Hanson, L.N.1    Engelman, H.M.2    Alekel, D.L.3    Schalinske, K.L.4    Kohut, M.L.5    Reddy, M.B.6
  • 39
    • 31544453293 scopus 로고    scopus 로고
    • Consumption of soy isoflavones does not affect plasma total homocysteine or asymmetric dimethylarginine concentrations in healthy postmenopausal women
    • Reimann M., Dierkes J., Carlsohn A., Talbot D., Ferrari M., Hallund J., et al. Consumption of soy isoflavones does not affect plasma total homocysteine or asymmetric dimethylarginine concentrations in healthy postmenopausal women. J Nutr 2006, 136:100-105.
    • (2006) J Nutr , vol.136 , pp. 100-105
    • Reimann, M.1    Dierkes, J.2    Carlsohn, A.3    Talbot, D.4    Ferrari, M.5    Hallund, J.6
  • 41
    • 3042635791 scopus 로고    scopus 로고
    • Endometrial effects of long-term treatment with phytoestrogens: a randomized, double-blind, placebo-controlled study
    • Unfer V., Casini M.L., Costabile L., Mignosa M., Gerli S., Di Renzo G.C. Endometrial effects of long-term treatment with phytoestrogens: a randomized, double-blind, placebo-controlled study. Fertil Steril 2004, 82:145-148.
    • (2004) Fertil Steril , vol.82 , pp. 145-148
    • Unfer, V.1    Casini, M.L.2    Costabile, L.3    Mignosa, M.4    Gerli, S.5    Di Renzo, G.C.6
  • 42
    • 2542553389 scopus 로고    scopus 로고
    • Soya food intake and risk of endometrial cancer among Chinese women in Shanghai: population based case-control study
    • Xu W.H., Zheng W., Xiang Y.B., Ruan Z.X., Cheng J.R., Dai Q., et al. Soya food intake and risk of endometrial cancer among Chinese women in Shanghai: population based case-control study. BMJ 2004, 328:1285.
    • (2004) BMJ , vol.328 , pp. 1285
    • Xu, W.H.1    Zheng, W.2    Xiang, Y.B.3    Ruan, Z.X.4    Cheng, J.R.5    Dai, Q.6


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