Transient expressions of doppel and its structural analog prionΔ32-121 in SH-SY5Y cells caused cytotoxicity possibly by triggering similar apoptosis pathway

Molecular Biology Reports

Volumn 37, Issue 5, 2010, Pages 2549-2558

  Xu, K ^a,b   Wang, X ^b   Tian, C ^b   Shi, S ^b   Wang, G R ^b   Shi, Q ^b   Li, P ^b   Zhou, R M ^b   Jiang, H Y ^b   Chu, Y L ^a   Dong, X P ^b  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

Apoptosis; Cytotoxicity; Dpl; Mitochondria; PrP 32 121

Indexed keywords

CELL MEMBRANE PROTEIN; DOPPEL; LIPOCORTIN 5; PRION PROTEIN; PROCASPASE 3; PROTEIN BCL 2; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL LEVEL; CONTROLLED STUDY; CYTOTOXICITY; GENE ACTIVITY; GENE DELETION; GENE SEQUENCE; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROBLASTOMA CELL; RECOMBINANT PLASMID; STRUCTURAL HOMOLOGY; TRANSIENT EXPRESSION;

ANNEXIN A5; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; GPI-LINKED PROTEINS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MUTANT PROTEINS; PRIONS; PROPIDIUM; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TRANSFECTION;

MAMMALIA;

EID: 77955659356     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-009-9772-3     Document Type: Article

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