Anti-α4β1 integrin antibody induces receptor internalization and does not impair the function of circulating neutrophilic leukocytes

Inflammation Research

Volumn 59, Issue 8, 2010, Pages 647-657

  Fleming, Jennifer C ^a,b   Bao, Feng ^a   Cepinskas, Gediminas ^b   Weaver, Lynne C ^a  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

Author keywords

4 1 integrin; Internalization; Monoclonal antibody; Oxidative activity; Phagocytosis; Spinal cord injury

Indexed keywords

ALPHA4 INTEGRIN; ALPHA4 INTEGRIN MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 4; VERY LATE ACTIVATION ANTIGEN 4 MONOCLONAL ANTIBODY; FORMYLMETHIONYLLEUCYLPHENYLALANINE; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY LABELING; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; INCUBATION TIME; INTERNALIZATION; LEUKOCYTE ACTIVATION; LEUKOCYTE FUNCTION; NEUTROPHIL; NONHUMAN; OXIDATION REDUCTION REACTION; PHAGOCYTOSIS; RAT; ANIMAL; CYTOLOGY; DRUG EFFECT; IMMUNOLOGY; METABOLISM; NEUTROPHIL CHEMOTAXIS; SPINAL CORD INJURY; WISTAR RAT;

ANIMALS; ANTIBODIES, MONOCLONAL; CHEMOTAXIS, LEUKOCYTE; FEMALE; INTEGRIN ALPHA4BETA1; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHIL ACTIVATION; NEUTROPHILS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SPINAL CORD INJURIES; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77955659095     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-010-0177-5     Document Type: Article

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