Blockade of signaling via the very late antigen (VLA-4) and its counterligand vascular cell adhesion molecule-1 (VCAM-1) causes increased T cell apoptosis in experimental autoimmune neuritis

Acta Neuropathologica

Volumn 103, Issue 2, 2002, Pages 131-136

  Leussink, V I ^a   Zettl, U K ^b   Jander, S ^c   Pepinsky, R B ^d   Lobb, R R ^d   Stoll, G ^c   Toyka, K V ^a   Gold, R ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF ROSTOCK   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

^d BIOGEN   (United States)

Author keywords

Apoptosis; Autoimmunity; Integrins; Neuritis; T lymphocyte

Indexed keywords

GAMMA INTERFERON; LEUKOCYTE ANTIGEN; LYMPHOCYTE ANTIBODY; MESSENGER RNA; MONOCLONAL ANTIBODY; NITRIC OXIDE SYNTHASE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ANTIGEN 4;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; FEMALE; LYMPHOCYTIC INFILTRATION; MOLECULAR INTERACTION; NEURITIS; NONHUMAN; PERFUSION; PRIORITY JOURNAL; RAT; RAT STRAIN; SCIATIC NERVE; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TIME;

ANIMALS; ANTI-ALLERGIC AGENTS; APOPTOSIS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; INTEGRIN ALPHA4BETA1; INTEGRINS; NEURITIS, AUTOIMMUNE, EXPERIMENTAL; RATS; RATS, INBRED LEW; RECEPTORS, LYMPHOCYTE HOMING; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TIME FACTORS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0036943329     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010100444     Document Type: Article

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