Future research in ITP: An ICIS consensus

Annals of Hematology

Volumn 89, Issue SUPPL. 1, 2010, Pages

  Zehnder, James L ^a   Semple, John W ^b   Imbach, Paul ^c   Neufeld, Ellis J ^d   Buchanan, George R ^e   Cines, Douglas B ^f  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF BASEL   (Switzerland)

^d HARVARD MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF TEXAS AT DALLAS   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Autoimmune diseases; Immune thrombocytopenia; ITP

Indexed keywords

DEXAMETHASONE; HEMOSTATIC AGENT; PREDNISONE; RITUXIMAB; THROMBOPOIETIN RECEPTOR AGONIST; UNCLASSIFIED DRUG;

AUTOIMMUNE THROMBOCYTOPENIA; CLINICAL FEATURE; CLINICAL RESEARCH; CONSENSUS DEVELOPMENT; DISEASE COURSE; DRUG MEGADOSE; DRUG TARGETING; HUMAN; IMMUNOLOGY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; QUALITY OF LIFE; REGISTER; REVIEW; SPLENECTOMY; TREATMENT OUTCOME; ADULT; AGE; ANIMAL; CHILD; COMPLICATION; DISEASE MODEL; HELICOBACTER INFECTION; HELICOBACTER PYLORI; MOLECULARLY TARGETED THERAPY; PATHOPHYSIOLOGY; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; TRENDS;

ADULT; AGE FACTORS; ANIMALS; CHILD; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MOLECULAR TARGETED THERAPY; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC;

EID: 77955657705     PISSN: 09395555     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00277-010-0917-1     Document Type: Review

References (29)

1. F Rodeghiero, et al. 2009 Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group Blood 113 11 2386 2393 10.1182/blood-2008-07-162503 1:CAS:528:DC%2BD1MXjsFKhurs%3D 19005182
2. PE Abrahamson, et al. 2009 The incidence of idiopathic thrombocytopenic purpura among adults: a population-based study and literature review Eur J Haematol 83 2 83 89 10.1111/j.1600-0609.2009.01247.x 19245532
3. DB Cines, et al. 2009 The ITP syndrome: pathogenic and clinical diversity Blood 113 26 6511 6521 10.1182/blood-2009-01-129155 1:CAS:528: DC%2BD1MXotlWrur0%3D 19395674
4. H Sukati, et al. 2007 Mapping helper T-cell epitopes on platelet membrane glycoprotein IIIa in chronic autoimmune thrombocytopenic purpura Blood 109 10 4528 4538 10.1182/blood-2006-09-044388 1:CAS:528:DC%2BD2sXls1amtr4%3D 17272505
5. XL Zhang J Peng JZ Sun JJ Liu CS Guo ZG Wang Y Yu Y Shi P Qin SG Li LN Zhang M Hou 2009 De novo induction of platelet-specific CD4(+)CD25(+) regulatory T cells from CD4(+)CD25(-) cells in patients with idiopathic thrombocytopenic purpura Blood 113 11 2568 2577 10.1182/blood-2008-03-148288 1:CAS:528: DC%2BD1MXjsFKgsrs%3D 19056692
6. ZX Guo, et al. 2009 The role of Th17 cells in adult patients with chronic idiopathic thrombocytopenic purpura Eur J Haematol 82 6 488 489 10.1111/j.1600-0609.2009.01229.x 1:CAS:528:DC%2BD1MXmtVyls7c%3D 19187277
7. Semple JW (2009) Infections, antigen-presenting cells,T cells, and immune tolerance: their role in the pathogenesis of immune thrombocytopenia. Hematol Oncol Clin N Am (in press)
8. B Olsson, et al. 2008 Recruitment of T cells into bone marrow of ITP patients possibly due to elevated expression of VLA-4 and CX3CR1 Blood 112 4 1078 1084 10.1182/blood-2008-02-139402 1:CAS:528:DC%2BD1cXpvVOksb0%3D 18519809
9. B Olsson P Andersson M Jernås S Jacobsson B Carlsson LM Carlsson H Wadenvik 2003 T-cell-mediated cytotoxicity toward platelets in chronic idiopathic thrombocytopenic purpura Nat Med 9 9 1123 1124 10.1038/nm921 1:CAS:528:DC%2BD3sXmvVWns78%3D 12937414
10. Liebman HA (2008) Immune thrombocytopenia (ITP): an historical perspective. Hematology Am Soc Hematol Educ Program, 205
11. W Zhang, et al. 2009 Role of molecular mimicry of hepatitis C virus protein with platelet GPIIIa in hepatitis C-related immunologic thrombocytopenia Blood 113 17 4086 4093 10.1182/blood-2008-09-181073 1:CAS:528: DC%2BD1MXlsVWrtro%3D 19023115
12. PJ Ballem, et al. 1992 Kinetic studies of the mechanism of thrombocytopenia in patients with human immunodeficiency virus infection N Engl J Med 327 25 1779 1784 1:STN:280:DyaK3s%2FmtlWgsw%3D%3D 1435932
13. T Burger J Schnell M Schmelczer 1979 Platelet turnover and megakaryocytopoiesis in ITP Acta Med Acad Sci Hung 36 1 45 51 1:STN:280:DyaL3c7gsFyntA%3D%3D 575013
14. R McMillan, et al. 2004 Suppression of in vitro megakaryocyte production by antiplatelet autoantibodies from adult patients with chronic ITP Blood 103 4 1364 1369 10.1182/blood-2003-08-2672 1:CAS:528:DC%2BD2cXhsVSltbw%3D 14576051
15. JB Bussel, et al. 2009 Safety and efficacy of long-term treatment with romiplostim in thrombocytopenic patients with chronic ITP Blood 113 10 2161 2171 10.1182/blood-2008-04-150078 1:CAS:528:DC%2BD1MXjt12nt7g%3D 18981291
16. JB Bussel, et al. 2009 Effect of eltrombopag on platelet counts and bleeding during treatment of chronic idiopathic thrombocytopenic purpura: a randomised, double-blind, placebo-controlled trial Lancet 373 9664 641 648 10.1016/S0140-6736(09)60402-5 1:CAS:528:DC%2BD1MXitFyrsLY%3D 19231632
17. Stasi R, Provan D (2008) Helicobacter pylori and chronic ITP. Hematology Am Soc Hematol Educ Program, 206-211
18. DM Arnold, et al. 2009 Platelet count response to H. pylori treatment in patients with immune thrombocytopenic purpura with and without H. pylori infection: a systematic review Haematologica 94 6 850 856 10.3324/haematol.2008. 005348 19483158
19. Z Li, et al. 2005 Role of molecular mimicry to HIV-1 peptides in HIV-1-related immunologic thrombocytopenia Blood 106 2 572 576 10.1182/blood-2005-01-0243 1:CAS:528:DC%2BD2MXmtleqtr0%3D 15774614
20. PJ Newman R Aster B Boylan 2007 Human platelets circulating in mice: applications for interrogating platelet function and survival, the efficacy of antiplatelet therapeutics, and the molecular basis of platelet immunological disorders J Thromb Haemost 5 Suppl 1 305 309 10.1111/j.1538-7836.2007.02466.x 17635741
21. R Sood W Wong J Gotlib M Jeng JL Zehnder 2008 Gene expression and pathway analysisof immune thrombocytopenia Br J Haematol 140 1 99 103 1:CAS:528:DC%2BD1cXitVOnt70%3D 18005267
22. MB Zhang R Sood C Jones W Wong M Jeng JL Zehnder 2008 Elevated vanin1 and advillin expression is associated with progression to chronic ITP in children Blood 112 397a 10.1182/blood-2008-03-147090
23. CB Foster, et al. 2001 Polymorphisms in inflammatory cytokines and Fcgamma receptors in childhood chronic immune thrombocytopenic purpura: a pilot study Br J Haematol 113 3 596 599 10.1046/j.1365-2141.2001.02807.x 1:CAS:528:DC%2BD3MXkvFehsLY%3D 11380443
24. MD Carcao, et al. 2003 Fcgamma receptor IIa and IIIa polymorphisms in childhood immune thrombocytopenic purpura Br J Haematol 120 1 135 141 10.1046/j.1365-2141.2003.04033.x 1:CAS:528:DC%2BD3sXhtlKgsL8%3D 12492589
25. R Tamminga, et al. 2009 Possible lower rate of chronic ITP after IVIG for acute childhood ITP: an analysis from registry I of the Intercontinental Cooperative ITP Study Group (ICIS) Br J Haematol 146 2 180 184 10.1111/j.1365-2141.2009.07743.x 19466971
26. T Kuhne, et al. 2000 Ethnicity and environment may affect the phenotype of immune thrombocytopenic purpura in children Pediatr Res 48 3 374 379 10.1203/00006450-200009000-00019 1:STN:280:DC%2BD3M7ht1SrtQ%3D%3D 10960506
27. CE Neunert, et al. 2009 Relationships among bleeding severity, health-related quality of life, and platelet count in children with immune thrombocytopenic purpura Pediatr Blood Cancer 53 4 652 654 10.1002/pbc.21978 19492316
28. Y Cheng, et al. 2003 Initial treatment of immune thrombocyopenic purpura with high-dose dexamethasone N Engl J Med 349 831 836 10.1056/NEJMoa030254 1:CAS:528:DC%2BD3sXmvVSnsLw%3D 12944568
29. MG Mazzucconi, et al. 2007 Therapy with high-dose dexamethasone (HD-DXM) in previously untreated patients affected by idiopathic thrombocytopenic purpura: a GIMEMA experience Blood 109 4 1401 1407 10.1182/blood-2005-12-015222 1:CAS:528:DC%2BD2sXjt1CgsrY%3D 17077333