TRIB3 R84 variant affects glucose homeostasis by altering the interplay between insulin sensitivity and secretion

Diabetologia

Volumn 53, Issue 7, 2010, Pages 1354-1361

  Prudente, S ^a   Baratta, R ^b   Andreozzi, F ^c   Morini, E ^a   Farina, M G ^b   Nigro, A ^b   Copetti, M ^a   Pellegrini, F ^a   Succurro, E ^c   Di Pietrantonio, L ^a   Brufani, C ^d   Barbetti, F ^d   Dallapiccola, B ^a   Sesti, G ^c   Trischitta, V ^a,d,e   Frittitta, L ^b  

^a CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^b UNIVERSITY OF CATANIA   (Italy)

^c UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^d BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Akt; Early type 2 diabetes; Inhibitors of insulin signalling

Indexed keywords

INSULIN; MAMMALIAN TRIBBLES HOMOLOGUE 3; PROTEIN TRIB3; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; EUROPE; FEMALE; GENETIC RISK; GENOTYPE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HETEROZYGOTE; HUMAN; INSULIN RELEASE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; CELL CYCLE PROTEINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GLUCOSE; HOMEOSTASIS; HUMANS; INSULIN; INSULIN RESISTANCE; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; PROTEIN-SERINE-THREONINE KINASES; REPRESSOR PROTEINS; YOUNG ADULT;

EID: 77955657265     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1749-1     Document Type: Article

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